-
1
-
-
79959359494
-
Spondyloarthritis
-
Dougados M, Baeten D,. Spondyloarthritis. Lancet 2011; 377: 2127-37.
-
(2011)
Lancet
, vol.377
, pp. 2127-2137
-
-
Dougados, M.1
Baeten, D.2
-
2
-
-
35748981184
-
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
DOI 10.1038/ng.2007.17, PII NG200717
-
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007; 39: 1329-37. (Pubitemid 350041542)
-
(2007)
Nature Genetics
, vol.39
, Issue.11
, pp. 1329-1337
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
Kwiatkowski, D.P.7
McCarthy, M.I.8
Ouwehand, W.H.9
Samani, N.J.10
Todd, J.A.11
Donnelly, P.12
Barrett, J.C.13
Davison, D.14
Easton, D.15
Evans, D.M.16
Leung, H.-T.17
Marchini, J.L.18
Morris, A.P.19
Spencer, C.C.A.20
Tobin, M.D.21
Attwood, A.P.22
Boorman, J.P.23
Cant, B.24
Everson, U.25
Hussey, J.M.26
Jolley, J.D.27
Knight, A.S.28
Koch, K.29
Meech, E.30
Nutland, S.31
Prowse, C.V.32
Stevens, H.E.33
Taylor, N.C.34
Walters, G.R.35
Walker, N.M.36
Watkins, N.A.37
Winzer, T.38
Jones, R.W.39
McArdle, W.L.40
Ring, S.M.41
Strachan, D.P.42
Pembrey, M.43
Breen, G.44
Clair, D.St.45
Caesar, S.46
Gordon-Smith, K.47
Jones, L.48
Fraser, C.49
Green, E.K.50
Grozeva, D.51
Hamshere, M.L.52
Holmans, P.A.53
Jones, I.R.54
Kirov, G.55
Moskivina, V.56
Nikolov, I.57
O'Donovan, M.C.58
Owen, M.J.59
Collier, D.A.60
Elkin, A.61
Farmer, A.62
Williamson, R.63
McGuffin, P.64
Young, A.H.65
Ferrier, I.N.66
Ball, S.G.67
Balmforth, A.J.68
Barrett, J.H.69
Bishop, T.D.70
Iles, M.M.71
Maqbool, A.72
Yuldasheva, N.73
Hall, A.S.74
Braund, P.S.75
Dixon, R.J.76
Mangino, M.77
Stevens, S.78
Thompson, J.R.79
Bredin, F.80
Tremelling, M.81
Parkes, M.82
Drummond, H.83
Lees, C.W.84
Nimmo, E.R.85
Satsangi, J.86
Fisher, S.A.87
Forbes, A.88
Lewis, C.M.89
Onnie, C.M.90
more..
-
3
-
-
75749085686
-
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
-
Reveille JD, Sims AM, Danoy P, Evans DM, Leo P, Pointon JJ, et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet 2010; 42: 123-7.
-
(2010)
Nat Genet
, vol.42
, pp. 123-127
-
-
Reveille, J.D.1
Sims, A.M.2
Danoy, P.3
Evans, D.M.4
Leo, P.5
Pointon, J.J.6
-
4
-
-
78650711124
-
Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease
-
Danoy P, Pryce K, Hadler J, Bradbury LA, Farrar C, Pointon J, et al. Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease. PLoS Genet 2010; 6: e1001195.
-
(2010)
PLoS Genet
, vol.6
-
-
Danoy, P.1
Pryce, K.2
Hadler, J.3
Bradbury, L.A.4
Farrar, C.5
Pointon, J.6
-
5
-
-
79960899377
-
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
-
Evans DM, Spencer CC, Pointon JJ, Su Z, Harvey D, Kochan G, et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet 2011; 43: 761-7.
-
(2011)
Nat Genet
, vol.43
, pp. 761-767
-
-
Evans, D.M.1
Spencer, C.C.2
Pointon, J.J.3
Su, Z.4
Harvey, D.5
Kochan, G.6
-
6
-
-
33947177232
-
Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rβ2 expression during human Th1 cell differentiation
-
DOI 10.1038/sj.emboj.7601586, PII 7601586
-
Letimier FA, Passini N, Gasparian S, Bianchi E, Rogge L,. Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rβ2 expression during human Th1 cell differentiation. EMBO J 2007; 26: 1292-302. (Pubitemid 46398709)
-
(2007)
EMBO Journal
, vol.26
, Issue.5
, pp. 1292-1302
-
-
Letimier, F.A.1
Passini, N.2
Gasparian, S.3
Bianchi, E.4
Rogge, L.5
-
7
-
-
76249125198
-
Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells
-
Placek K, Gasparian S, Coffre M, Maiella S, Sechet E, Bianchi E, et al. Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells. J Immunol 2009; 183: 7743-51.
-
(2009)
J Immunol
, vol.183
, pp. 7743-7751
-
-
Placek, K.1
Gasparian, S.2
Coffre, M.3
Maiella, S.4
Sechet, E.5
Bianchi, E.6
-
8
-
-
77953917067
-
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
-
Wei L, Vahedi G, Sun HW, Watford WT, Takatori H, Ramos HL, et al. Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation. Immunity 2010; 32: 840-51.
-
(2010)
Immunity
, vol.32
, pp. 840-851
-
-
Wei, L.1
Vahedi, G.2
Sun, H.W.3
Watford, W.T.4
Takatori, H.5
Ramos, H.L.6
-
9
-
-
33846966636
-
H2 hypothesis of T cell-mediated tissue damage
-
[published erratum appears in Nat Med 2007;13:385]
-
H2 hypothesis of T cell-mediated tissue damage [published erratum appears in Nat Med 2007;13:385]. Nat Med 2007; 13: 139-45.
-
(2007)
Nat Med
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
10
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13: 715-25.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
-
11
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
DOI 10.1038/nature01355
-
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003; 421: 744-8. (Pubitemid 36227625)
-
(2003)
Nature
, vol.421
, Issue.6924
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
12
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233-40. (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
13
-
-
0346962972
-
Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
-
DOI 10.1084/jem.20030896
-
Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 2003; 198: 1951-7. (Pubitemid 38032126)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.12
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
14
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
DOI 10.1084/jem.20061099
-
Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med 2006; 203: 2473-83. (Pubitemid 44664617)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.11
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.S.6
Powrie, F.7
Maloy, K.J.8
-
15
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006; 116: 1310-6.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
-
16
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
DOI 10.1074/jbc.M207577200
-
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL,. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003; 278: 1910-4. (Pubitemid 36801431)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.3
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.-H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
17
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
DOI 10.1038/ni1254, PII N1254
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6: 1123-32. (Pubitemid 41541790)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
18
-
-
49449115544
-
Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
-
Jandus C, Bioley G, Rivals JP, Dudler J, Speiser D, Romero P,. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 2008; 58: 2307-17.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2307-2317
-
-
Jandus, C.1
Bioley, G.2
Rivals, J.P.3
Dudler, J.4
Speiser, D.5
Romero, P.6
-
19
-
-
40549138745
-
Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers
-
DOI 10.1002/art.23291
-
Nistala K, Moncrieffe H, Newton KR, Varsani H, Hunter P, Wedderburn LR,. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum 2008; 58: 875-87. (Pubitemid 351364887)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.3
, pp. 875-887
-
-
Nistala, K.1
Moncrieffe, H.2
Newton, K.R.3
Varsani, H.4
Hunter, P.5
Wedderburn, L.R.6
-
20
-
-
66449133523
-
Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
-
Shen H, Goodall JC, Hill Gaston JS,. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum 2009; 60: 1647-56.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1647-1656
-
-
Shen, H.1
Goodall, J.C.2
Hill Gaston, J.S.3
-
22
-
-
84858644639
-
Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis
-
Kenna TJ, Davidson SI, Duan R, Bradbury LA, McFarlane J, Smith M, et al. Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis. Arthritis Rheum 2012; 64: 1420-9.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1420-1429
-
-
Kenna, T.J.1
Davidson, S.I.2
Duan, R.3
Bradbury, L.A.4
McFarlane, J.5
Smith, M.6
-
23
-
-
46949086111
-
A rush to judgment on Th17
-
DOI 10.1084/jem.20072066
-
Steinman L,. A rush to judgment on Th17. J Exp Med 2008; 205: 1517-22. (Pubitemid 351962013)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.7
, pp. 1517-1522
-
-
Steinman, L.1
-
24
-
-
74049099080
-
Autoimmunity: Increasing suspects in the CD4+ T cell lineup
-
Palmer MT, Weaver CT,. Autoimmunity: increasing suspects in the CD4+ T cell lineup. Nat Immunol 2010; 11: 36-40.
-
(2010)
Nat Immunol
, vol.11
, pp. 36-40
-
-
Palmer, M.T.1
Weaver, C.T.2
-
25
-
-
0021272107
-
Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria
-
Van der Linden S, Valkenburg HA, Cats A,. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 1984; 27: 361-8. (Pubitemid 14134775)
-
(1984)
Arthritis and Rheumatism
, vol.27
, Issue.4
, pp. 361-368
-
-
Van Der Linden, S.1
Valkenburg, H.A.2
Cats, A.3
-
26
-
-
0025377351
-
Criteria of the classification of spondylarthropathies
-
In French
-
Amor B, Dougados M, Mijiyawa M,. Criteria of the classification of spondylarthropathies. Rev Rhum Mal Osteoartic 1990; 57: 85-9. In French.
-
(1990)
Rev Rhum Mal Osteoartic
, vol.57
, pp. 85-89
-
-
Amor, B.1
Dougados, M.2
Mijiyawa, M.3
-
27
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
DOI 10.1007/s00439-007-0397-0
-
Capon F, Di Meglio P, Szaub J, Prescott NJ, Dunster C, Baumber L, et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet 2007; 122: 201-6. (Pubitemid 47241785)
-
(2007)
Human Genetics
, vol.122
, Issue.2
, pp. 201-206
-
-
Capon, F.1
Di Meglio, P.2
Szaub, J.3
Prescott, N.J.4
Dunster, C.5
Baumber, L.6
Timms, K.7
Gutin, A.8
Abkevic, V.9
Burden, A.D.10
Lanchbury, J.11
Barker, J.N.12
Trembath, R.C.13
Nestle, F.O.14
-
28
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
DOI 10.1086/511051
-
Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007; 80: 273-90. (Pubitemid 46175676)
-
(2007)
American Journal of Human Genetics
, vol.80
, Issue.2
, pp. 273-290
-
-
Cargill, M.1
Schrodi, S.J.2
Chang, M.3
Garcia, V.E.4
Brandon, R.5
Callis, K.P.6
Matsunami, N.7
Ardlie, K.G.8
Civello, D.9
Catanese, J.J.10
Leong, D.U.11
Panko, J.M.12
McAllister, L.B.13
Hansen, C.B.14
Papenfuss, J.15
Prescott, S.M.16
White, T.J.17
Leppert, M.F.18
Krueger, G.G.19
Begovich, A.B.20
more..
-
29
-
-
43249083380
-
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
-
Liu Y, Helms C, Liao W, Zaba LC, Duan S, Gardner J, et al. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet 2008; 4: e1000041.
-
(2008)
PLoS Genet
, vol.4
-
-
Liu, Y.1
Helms, C.2
Liao, W.3
Zaba, L.C.4
Duan, S.5
Gardner, J.6
-
30
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-62.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
31
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
DOI 10.1038/ni1467, PII NI1467
-
Acosta-Rodriguez EV, Rivino L, Geginat J, Jarrossay D, Gattorno M, Lanzavecchia A, et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007; 8: 639-46. (Pubitemid 46785128)
-
(2007)
Nature Immunology
, vol.8
, Issue.6
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
32
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
DOI 10.1084/jem.20070663
-
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, et al. Phenotypic and functional features of human Th17 cells. J Exp Med 2007; 204: 1849-61. (Pubitemid 47240944)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.8
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Fili, L.8
Ferri, S.9
Frosali, F.10
Giudici, F.11
Romagnani, P.12
Parronchi, P.13
Tonelli, F.14
Maggi, E.15
Romagnani, S.16
-
33
-
-
61949463911
-
IL-17 and Th17 cells
-
Korn T, Bettelli E, Oukka M, Kuchroo VK,. IL-17 and Th17 cells. Annu Rev Immunol 2009; 27: 485-517.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
34
-
-
34548427925
-
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
-
DOI 10.1056/NEJMoa073003
-
Remmers EF, Plenge RM, Lee AT, Graham RR, Hom G, Behrens TW, et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med 2007; 357: 977-86. (Pubitemid 47367077)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.10
, pp. 977-986
-
-
Remmers, E.F.1
Plenge, R.M.2
Lee, A.T.3
Graham, R.R.4
Hom, G.5
Behrens, T.W.6
De Bakker, P.I.W.7
Le, J.M.8
Lee, H.-S.9
Batliwalla, F.10
Li, W.11
Masters, S.L.12
Booty, M.G.13
Carulli, J.P.14
Padyukov, L.15
Alfredsson, L.16
Klareskog, L.17
Chen, W.V.18
Amos, C.I.19
Criswell, L.A.20
Seldin, M.F.21
Kastner, D.L.22
Gregersen, P.K.23
more..
-
35
-
-
79959335758
-
Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses
-
Sarin R, Wu X, Abraham C,. Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses. Proc Natl Acad Sci U S A 2011; 108: 9560-5.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9560-9565
-
-
Sarin, R.1
Wu, X.2
Abraham, C.3
-
36
-
-
79952066088
-
The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans
-
Di Meglio P, Di Cesare A, Laggner U, Chu CC, Napolitano L, Villanova F, et al. The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans. PLoS One 2011; 6: e17160.
-
(2011)
PLoS One
, vol.6
-
-
Di Meglio, P.1
Di Cesare, A.2
Laggner, U.3
Chu, C.C.4
Napolitano, L.5
Villanova, F.6
-
37
-
-
80053991071
-
Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q
-
Pidasheva S, Trifari S, Phillips A, Hackney JA, Ma Y, Smith A, et al. Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q. PLoS One 2011; 6: e25038.
-
(2011)
PLoS One
, vol.6
-
-
Pidasheva, S.1
Trifari, S.2
Phillips, A.3
Hackney, J.A.4
Ma, Y.5
Smith, A.6
-
38
-
-
49449087247
-
IL-23 and IL-12 responses in activated human T cells retrovirally transduced with IL-23 receptor variants
-
De Paus RA, van de Wetering D, van Dissel JT, van de Vosse E,. IL-23 and IL-12 responses in activated human T cells retrovirally transduced with IL-23 receptor variants. Mol Immunol 2008; 45: 3889-95.
-
(2008)
Mol Immunol
, vol.45
, pp. 3889-3895
-
-
De Paus, R.A.1
Van De Wetering, D.2
Van Dissel, J.T.3
Van De Vosse, E.4
-
39
-
-
80052325959
-
Pervasive sharing of genetic effects in autoimmune disease
-
Cotsapas C, Voight BF, Rossin E, Lage K, Neale BM, Wallace C, et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet 2011; 7: e1002254.
-
(2011)
PLoS Genet
, vol.7
-
-
Cotsapas, C.1
Voight, B.F.2
Rossin, E.3
Lage, K.4
Neale, B.M.5
Wallace, C.6
-
40
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
-
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R. J Immunol 2002; 168: 5699-708. (Pubitemid 34556153)
-
(2002)
Journal of Immunology
, vol.168
, Issue.11
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
To, W.11
Wagner, J.12
O'Farrell, A.-M.13
McClanahan, T.14
Zurawski, S.15
Hannum, C.16
Gorman, D.17
Rennick, D.M.18
Kastelein, R.A.19
De Waal Malefyt, R.20
Moore, K.W.21
more..
-
42
-
-
35348960378
-
STAT3 mutations in the hyper-IgE syndrome
-
DOI 10.1056/NEJMoa073687
-
Holland SM, DeLeo FR, Elloumi HZ, Hsu AP, Uzel G, Brodsky N, et al. STAT3 mutations in the hyper-IgE syndrome. N Engl J Med 2007; 357: 1608-19. (Pubitemid 47598403)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.16
, pp. 1608-1619
-
-
Holland, S.M.1
DeLeo, F.R.2
Elloumi, H.Z.3
Hsu, A.P.4
Uzel, G.5
Brodsky, N.6
Freeman, A.F.7
Demidowich, A.8
Davis, J.9
Turner, M.L.10
Anderson, V.L.11
Darnell, D.N.12
Welch, P.A.13
Kuhns, D.B.14
Frucht, D.M.15
Malech, H.L.16
Gallin, J.I.17
Kobayashi, S.D.18
Whitney, A.R.19
Voyich, J.M.20
Musser, J.M.21
Woellner, C.22
Schaffer, A.A.23
Puck, J.M.24
Grimbacher, B.25
more..
-
43
-
-
46949086109
-
Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells
-
DOI 10.1084/jem.20080321
-
De Beaucoudrey L, Puel A, Filipe-Santos O, Cobat A, Ghandil P, Chrabieh M, et al. Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells. J Exp Med 2008; 205: 1543-50. (Pubitemid 351962017)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.7
, pp. 1543-1550
-
-
De Beaucoudtey, L.1
Puel, A.2
Filipe-Santos, O.3
Cobat, A.4
Ghandil, P.5
Chrabieh, M.6
Felnberg, J.7
Von Bernuth, H.8
Samarina, A.9
Janniere, L.10
Fieschi, C.11
Stephan, J.-L.12
Boileau, C.13
Lyonnet, S.14
Jondeau, G.15
Cormier-Daire, V.16
Le Merrer, M.17
Hoarau, C.18
Lebranchu, Y.19
Lortholary, O.20
Chandesris, M.-O.21
Tron, F.22
Gambineri, E.23
Bianchi, L.24
Rodriguez-Gallego, C.25
Zitnik, S.E.26
Vasconcelos, J.27
Guedes, M.28
Vitor, A.B.29
Marodi, L.30
Chapel, H.31
Reid, B.32
Roifman, C.33
Nadal, D.34
Reichenbach, J.35
Caragol, I.36
Garty, B.-Z.37
Dogu, F.38
Camcioglu, Y.39
Gulle, S.40
Sanal, O.41
Fischer, A.42
Abel, L.43
Stockinger, B.44
Picard, C.45
Casanova, J.-L.46
more..
-
44
-
-
41449110468
-
H17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
-
DOI 10.1038/nature06764, PII NATURE06764
-
H17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008; 452: 773-6. (Pubitemid 351521078)
-
(2008)
Nature
, vol.452
, Issue.7188
, pp. 773-776
-
-
Milner, J.D.1
Brenchley, J.M.2
Laurence, A.3
Freeman, A.F.4
Hill, B.J.5
Elias, K.M.6
Kanno, Y.7
Spalding, C.8
Elloumi, H.Z.9
Paulson, M.L.10
Davis, J.11
Hsu, A.12
Asher, A.I.13
O'Shea, J.14
Holland, S.M.15
Paul, W.E.16
Douek, D.C.17
-
45
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity
-
Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH,. Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity. Immunity 2009; 31: 331-41.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
46
-
-
77955890952
-
Interleukin-23 drives intestinal inflammation through direct activity on T cells
-
Ahern PP, Schiering C, Buonocore S, McGeachy MJ, Cua DJ, Maloy KJ, et al. Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity 2010; 33: 279-88.
-
(2010)
Immunity
, vol.33
, pp. 279-288
-
-
Ahern, P.P.1
Schiering, C.2
Buonocore, S.3
McGeachy, M.J.4
Cua, D.J.5
Maloy, K.J.6
-
47
-
-
77951636478
-
Mast cells express IL-17A in rheumatoid arthritis synovium
-
Hueber AJ, Asquith DL, Miller AM, Reilly J, Kerr S, Leipe J, et al. Mast cells express IL-17A in rheumatoid arthritis synovium. J Immunol 2010; 184: 3336-40.
-
(2010)
J Immunol
, vol.184
, pp. 3336-3340
-
-
Hueber, A.J.1
Asquith, D.L.2
Miller, A.M.3
Reilly, J.4
Kerr, S.5
Leipe, J.6
-
48
-
-
84855291352
-
Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis
-
Noordenbos T, Yeremenko N, Gofita I, van de Sande M, Tak PP, Canete JD, et al. Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. Arthritis Rheum 2012; 64: 99-109.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 99-109
-
-
Noordenbos, T.1
Yeremenko, N.2
Gofita, I.3
Van De Sande, M.4
Tak, P.P.5
Canete, J.D.6
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