Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells

Journal of Immunology

Volumn 183, Issue 12, 2009, Pages 7743-7751

  Placek, Katarzyna ^a   Gasparian, Sona ^a,b   Coffre, Maryaline ^a   Maiella, Sylvie ^a   Sechet, Emmanuel ^a   Bianchi, Elisabetta ^a   Rogge, Lars ^a  

^a CNRS   (France)

^b ZI Les Paluds   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CYCLOSPORIN A; CYTOKINE RECEPTOR; DEOXYRIBONUCLEASE I; DNA; GAMMA INTERFERON; HISTONE; INTERLEUKIN 12; MESSENGER RNA; STAT4 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR T BET; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; NFATC1 PROTEIN, HUMAN; SIGNAL PEPTIDE; T BOX TRANSCRIPTION FACTOR; T BOX TRANSCRIPTION FACTOR TBX21; T-BOX TRANSCRIPTION FACTOR TBX21;

ACETYLATION; ARTICLE; CD4+ T LYMPHOCYTE; CHROMATIN; CONTROLLED STUDY; DNA MODIFICATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE LOCUS; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; GENETICS; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; REGULATORY SEQUENCE; TH2 CELL;

ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CYTOKINES; DEOXYRIBONUCLEASE I; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; NFATC TRANSCRIPTION FACTORS; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS;

EID: 76249125198     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803812     Document Type: Article

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