Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 13, 2013, Pages 3850-3858

  Teiten, Marie Hélène ^a   MacK, Fabienne ^a   Debbab, Abdessamad ^b   Aly, Amal H ^b   Dicato, Mario ^a   Proksch, Peter ^b   Diederich, Marc ^c  

^a LABORATOIRE DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE DU CANCER   (Luxembourg)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c Seoul National University   (South Korea)

Author keywords

Altersolanol A; Cell death; Cell migration; Cell proliferation; Human cancer cells

Indexed keywords

ALTERSOLANOL A; AMPELANOL; ANTHRACENE DERIVATIVE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOTOXIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TETRAACETYLALTERSOLANOL A; TETRAHYDROALTERSOLANOL B; UNCLASSIFIED DRUG; ANTHRAQUINONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CHRONIC MYELOID LEUKEMIA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSTASIS; DRUG ACETYLATION; DRUG CYTOTOXICITY; DRUG EFFECT; ENDOPHYTE; ENZYME MODIFICATION; FUNGUS; HUMAN; HUMAN CELL; LIPOPHILICITY; LUNG CANCER; PROTEIN EXPRESSION; STEMPHYLIUM GLOBULIFERUM; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; ASCOMYCETES; CELL MOTION; CHEMISTRY; DRUG EFFECTS; IMMUNOLOGY; ISOLATION AND PURIFICATION; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LUNG; LUNG NEOPLASMS; MENTHA PULEGIUM; MICROBIOLOGY; PATHOLOGY; TUMOR CELL LINE;

FUNGI; LAMIACEAE; MENTHA PULEGIUM; STEMPHYLIUM GLOBULIFERUM;

ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASCOMYCOTA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LUNG; LUNG NEOPLASMS; MENTHA PULEGIUM; NF-KAPPA B; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878600634     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.04.024     Document Type: Article

References (58)

1. M.S. Butler, D.J. Newman, Progres des recherches pharmaceutiques 65,2008, 1, 3-44.
2. M. Schumacher, C. Cerella, S. Eifes, S. Chateauvieux, F. Morceau, M. Jaspars, M. Dicato, and M. Diederich Biochem. Pharmacol. 79 2010 610
3. B. Orlikova, D. Tasdemir, F. Golais, M. Dicato, and M. Diederich Biochem. Pharmacol. 82 2011 620
4. T. Juncker, C. Cerella, M.H. Teiten, F. Morceau, M. Schumacher, J. Ghelfi, F. Gaascht, M. Schnekenburger, E. Henry, M. Dicato, and M. Diederich Biochem. Pharmacol. 81 2011 13
5. M.H. Teiten, S. Eifes, M. Dicato, and M. Diederich Toxins 2 2010 128
6. M. Karin, and F.R. Greten Nat. Rev. Immunol. 5 2005 749
7. S.I. Grivennikov, F.R. Greten, and M. Karin Cell 140 2010 883
8. M.M. Chaturvedi, B. Sung, V.R. Yadav, R. Kannappan, and B.B. Aggarwal Oncogene 30 2011 1615
9. G. Sethi, B. Sung, and B.B. Aggarwal Exp. Biol. Med. 233 2008 21
10. K.S. Ahn, G. Sethi, and B.B. Aggarwal Biochem. Pharmacol. 75 2008 907
11. S. Fulda Apoptosis 14 2009 409
12. S. Delhalle, R. Blasius, M. Dicato, and M. Diederich Ann. N.Y. Acad. Sci. 1030 2004 1
13. M.H. Teiten, F. Gaascht, S. Eifes, M. Dicato, and M. Diederich Genes Nutr. 5 2010 61
14. B. Orlikova, D. Tasdemir, F. Golais, M. Dicato, and M. Diederich Genes Nutr. 6 2011 125
15. C.J. Weng, and G.C. Yen Cancer Treat. Rev. 38 2012 76
16. F. Folmer, M. Jaspars, M. Dicato, and M. Diederich Biochem. Pharmacol. 75 2008 603
17. G.A. Strobel Crit. Rev. Biotechnol. 22 2002 315
18. H. Yu, L. Zhang, L. Li, C. Zheng, L. Guo, W. Li, P. Sun, and L. Qin Microbiol. Res. 165 2010 437
19. A.H. Aly, A. Debbab, J. Kjer, and P. Proksch Fungal Divers. 41 2010 1
20. A.H. Aly, A. Debbab, and P. Proksch Appl. Microbiol. Biotechnol. 90 2011 1829
21. A. Debbab, A.H. Aly, W.H. Lin, and P. Proksch Microb. Biotechnol. 3 2010 544
22. A. Debbab, A.H. Aly, and P. Proksch Fungal Divers. 49 2011 1
23. A. Debbab, A.H. Aly, R. Edrada-Ebel, V. Wray, W.E. Muller, F. Totzke, U. Zirrgiebel, C. Schachtele, M.H. Kubbutat, W.H. Lin, M. Mosaddak, A. Hakiki, P. Proksch, and R. Ebel J. Nat. Prod. 72 2009 626
24. S. Wang, X.M. Li, F. Teuscher, D.L. Li, A. Diesel, R. Ebel, P. Proksch, and B.G. Wang J. Nat. Prod. 69 2006 1622
25. A.H. Aly, R. Edrada-Ebel, V. Wray, W.E. Muller, S. Kozytska, U. Hentschel, P. Proksch, and R. Ebel Phytochemistry 69 2008 1716
26. A. Stoessl, C.H. Unwin, and J.B. Stothers Can. J. Chem. 61 1983 372
27. A.H. Aly, A. Debbab, R. Edrada-Ebel, W. Muller, M.H.G. Kubbutat, V. Wray, R. Ebel, and P. Proksch Mycosphere 1 2010 153
28. J.W. Gray, and P. Coffino Methods Enzymol. 58 1979 233
29. E. Schreiber, P. Matthias, M.M. Muller, and W. Schaffner Nucleic Acids Res. 17 1989 6419
30. A. Duvoix, S. Delhalle, R. Blasius, M. Schnekenburger, F. Morceau, M. Fougere, E. Henry, M.M. Galteau, M. Dicato, and M. Diederich Biochem. Pharmacol. 68 2004 1101
31. Y.J. Surh Nat. Rev. Cancer 3 2003 768
32. M.H. Pan, and C.T. Ho Chem. Soc. Rev. 37 2008 2558
33. R.G. Mehta, G. Murillo, R. Naithani, and X. Peng Pharm. Res. 27 2010 950
34. F. Javed, M.I. Qadir, K.H. Janbaz, and M. Ali Crit. Rev. Microbiol. 37 2011 245
35. G. Lazarovits, R.W. Steele, and A. Stoessl Z. Naturforsch. Sect. C 43c 1988 813
36. C.J. Porter, N.L. Trevaskis, and W.N. Charman Nat. Rev. Drug Disc. 6 2007 231
37. A. Begleiter Cancer Res. 43 1983 481
38. Z.S. Saify, N. Mushtaq, F. Noor, S. Takween, and M. Arif Pak. J. Pharm. Sci. 12 1999 21
39. V.R. Yadav, S. Prasad, B. Sung, and B.B. Aggarwal Int. Immunopharmacol. 11 2011 295
40. C.Y. Ma, W.T. Ji, F.S. Chueh, J.S. Yang, P.Y. Chen, C.C. Yu, and J.G. Chung J. Agric. Food Chem. 59 2011 9032
41. S. Reuter, S. Eifes, M. Dicato, B.B. Aggarwal, and M. Diederich Biochem. Pharmacol. 76 2008 1340
42. C. Akgul Cell. Mol. Life Sci. 66 2009 1326
43. P. Smolewski, and T. Robak Curr. Mol. Med. 11 2011 633
44. P.N. Kelly, and A. Strasser Cell Death Differ. 18 2011 1414
45. L.M. Coussens, and Z. Werb Nature 420 2002 860
46. T.D. Gilmore Oncogene 25 2006 6680
47. Y. Wu, and B.P. Zhou Br. J. Cancer 102 2010 639
48. K. Nabeshima, T. Inoue, Y. Shimao, and T. Sameshima Pathol. Int. 52 2002 255
49. C. Gialeli, A.D. Theocharis, and N.K. Karamanos FEBS J. 278 2011 16
50. A.K. Chaudhary, S. Pandya, K. Ghosh, and A. Nadkarni Mutat Res. 2013 10.1016/j.mrrev.2013.01.002
51. X.F. Yu, and Z.C. Han Histol. Histopathol. 21 2006 519
52. M. Stefanidakis, and E. Koivunen Blood 108 2006 1441
53. M. Bond, R.P. Fabunmi, A.H. Baker, and A.C. Newby FEBS Lett. 435 1998 29
54. H.J. Sung, Y. Kim, H. Kang, J.W. Sull, Y.S. Kim, S.W. Jang, and J. Ko Int. J. Mol. Med. 29 2012 245
55. S.J. Kao, J.L. Su, C.K. Chen, M.C. Yu, K.J. Bai, J.H. Chang, M.Y. Bien, S.F. Yang, and M.H. Chien Toxicol. Appl. Pharmacol. 261 2012 105
56. Y.S. Kim, J.W. Sull, and H.J. Sung Mol. Biol. Rep. 39 2012 8709
57. K.B. Harikumar, B. Sung, S.T. Tharakan, M.K. Pandey, B. Joy, S. Guha, S. Krishnan, and B.B. Aggarwal Mol. Cancer Res. 8 2010 751
58. S.C. Gupta, S. Prasad, S. Reuter, R. Kannappan, V.R. Yadav, J. Ravindran, P.S. Hema, M.M. Chaturvedi, M. Nair, and B.B. Aggarwal J. Biol. Chem. 285 2010 35406