-
1
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2: 675-680, 2001.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
2
-
-
0034037949
-
Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: Evidence for capillary recruitment
-
Baron AD, Tarshoby M, Hook G, Lazaridis EN, Cronin J, Johnson A, Steinberg HO. Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment. Diabetes 49: 768-774, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 768-774
-
-
Baron, A.D.1
Tarshoby, M.2
Hook, G.3
Lazaridis, E.N.4
Cronin, J.5
Johnson, A.6
Steinberg, H.O.7
-
3
-
-
33646933064
-
TLR1-and TLR6-independent recognition of bacterial lipopeptides
-
Buwitt-Beckmann U, Heine H, Wiesmuller KH, Jung G, Brock R, Akira S, Ulmer AJ. TLR1-and TLR6-independent recognition of bacterial lipopeptides. J Biol Chem 281: 9049-9057, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 9049-9057
-
-
Buwitt-Beckmann, U.1
Heine, H.2
Wiesmuller, K.H.3
Jung, G.4
Brock, R.5
Akira, S.6
Ulmer, A.J.7
-
4
-
-
57449083385
-
Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet
-
Caricilli AM, Nascimento PH, Pauli JR, Tsukumo DM, Velloso LA, Carvalheira JB, Saad MJ. Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet. J Endocrinol 199: 399-406, 2008.
-
(2008)
J Endocrinol
, vol.199
, pp. 399-406
-
-
Caricilli, A.M.1
Nascimento, P.H.2
Pauli, J.R.3
Tsukumo, D.M.4
Velloso, L.A.5
Carvalheira, J.B.6
Saad, M.J.7
-
5
-
-
84855174006
-
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice
-
Caricilli AM, Picardi PK, de Abreu LL, Ueno M, Prada PO, Ropelle ER, Hirabara SM, Castoldi A, Vieira P, Camara NO, Curi R, Carvalheira JB, Saad MJ. Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice. PLoS Biol 9: e1001212, 2011.
-
(2011)
PLoS Biol
, vol.9
-
-
Caricilli, A.M.1
Picardi, P.K.2
de Abreu, L.L.3
Ueno, M.4
Prada, P.O.5
Ropelle, E.R.6
Hirabara, S.M.7
Castoldi, A.8
Vieira, P.9
Camara, N.O.10
Curi, R.11
Carvalheira, J.B.12
Saad, M.J.13
-
6
-
-
21344454662
-
Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model
-
Chen H, Sullivan G, Quon MJ. Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model. Diabetes 54: 1914-1925, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 1914-1925
-
-
Chen, H.1
Sullivan, G.2
Quon, M.J.3
-
7
-
-
77953060025
-
Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects
-
Dasu MR, Devaraj S, Park S, Jialal I. Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care 33: 861-868, 2010.
-
(2010)
Diabetes Care
, vol.33
, pp. 861-868
-
-
Dasu, M.R.1
Devaraj, S.2
Park, S.3
Jialal, I.4
-
8
-
-
78650762257
-
Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes
-
Davis JE, Braucher DR, Walker-Daniels J, Spurlock ME. Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes. J Nutr Biochem 22: 136-141, 2011.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 136-141
-
-
Davis, J.E.1
Braucher, D.R.2
Walker-Daniels, J.3
Spurlock, M.E.4
-
9
-
-
0035902547
-
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase
-
Duplain H, Burcelin R, Sartori C, Cook S, Egli M, Lepori M, Vollenweider P, Pedrazzini T, Nicod P, Thorens B, Scherrer U. Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase. Circulation 104: 342-345, 2001.
-
(2001)
Circulation
, vol.104
, pp. 342-345
-
-
Duplain, H.1
Burcelin, R.2
Sartori, C.3
Cook, S.4
Egli, M.5
Lepori, M.6
Vollenweider, P.7
Pedrazzini, T.8
Nicod, P.9
Thorens, B.10
Scherrer, U.11
-
10
-
-
77950840619
-
Toll-like receptor 4 modulates skeletal muscle substrate metabolism
-
Frisard MI, McMillan RP, Marchand J, Wahlberg KA, Wu Y, Voelker KA, Heilbronn L, Haynie K, Muoio B, Li L, Hulver MW. Toll-like receptor 4 modulates skeletal muscle substrate metabolism. Am J Physiol Endocrinol Metab 298: E988-E998, 2010.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Frisard, M.I.1
McMillan, R.P.2
Marchand, J.3
Wahlberg, K.A.4
Wu, Y.5
Voelker, K.A.6
Heilbronn, L.7
Haynie, K.8
Muoio, B.9
Li, L.10
Hulver, M.W.11
-
11
-
-
40949126146
-
Resistin impairs insulin-evoked vasodilation
-
Gentile MT, Vecchione C, Marino G, Aretini A, Di Pardo A, Antenucci G, Maffei A, Cifelli G, Iorio L, Landolfi A, Frati G, Lembo G. Resistin impairs insulin-evoked vasodilation. Diabetes 57: 577-583, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 577-583
-
-
Gentile, M.T.1
Vecchione, C.2
Marino, G.3
Aretini, A.4
Di Pardo, A.5
Antenucci, G.6
Maffei, A.7
Cifelli, G.8
Iorio, L.9
Landolfi, A.10
Frati, G.11
Lembo, G.12
-
12
-
-
33748617142
-
PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function
-
Greene MW, Ruhoff MS, Roth RA, Kim JA, Quon MJ, Krause JA. PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function. Biochem Biophys Res Commun 349: 976-986, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 976-986
-
-
Greene, M.W.1
Ruhoff, M.S.2
Roth, R.A.3
Kim, J.A.4
Quon, M.J.5
Krause, J.A.6
-
13
-
-
58149484392
-
Inflammation and endoplasmic reticulum stress in obesity and diabetes
-
Hotamisligil GS. Inflammation and endoplasmic reticulum stress in obesity and diabetes. Int J Obes (Lond) 32, Suppl 7: S52-S54, 2008.
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.SUPPL. 7
-
-
Hotamisligil, G.S.1
-
14
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 271: 665-668, 1996.
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spiegelman, B.M.6
-
15
-
-
12344253633
-
Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species
-
Katakam PV, Tulbert CD, Snipes JA, Erdos B, Miller AW, Busija DW. Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species. Am J Physiol Heart Circ Physiol 288: H854-H860, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Katakam, P.V.1
Tulbert, C.D.2
Snipes, J.A.3
Erdos, B.4
Miller, A.W.5
Busija, D.W.6
-
16
-
-
34250169823
-
Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity
-
Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res 100: 1589-1596, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 1589-1596
-
-
Kim, F.1
Pham, M.2
Luttrell, I.3
Bannerman, D.D.4
Tupper, J.5
Thaler, J.6
Hawn, T.R.7
Raines, E.W.8
Schwartz, M.W.9
-
17
-
-
34250174411
-
Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn
-
Kim JA, Formoso G, Li Y, Potenza MA, Marasciulo FL, Montagnani M, Quon MJ. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. J Biol Chem 282: 13736-13745, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 13736-13745
-
-
Kim, J.A.1
Formoso, G.2
Li, Y.3
Potenza, M.A.4
Marasciulo, F.L.5
Montagnani, M.6
Quon, M.J.7
-
18
-
-
33646178955
-
Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
-
Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113: 1888-1904, 2006.
-
(2006)
Circulation
, vol.113
, pp. 1888-1904
-
-
Kim, J.A.1
Montagnani, M.2
Koh, K.K.3
Quon, M.J.4
-
19
-
-
20744448048
-
Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: Cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance
-
Kim JA, Yeh DC, Ver M, Li Y, Carranza A, Conrads TP, Veenstra TD, Harrington MA, Quon MJ. Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance. J Biol Chem 280: 23173-23183, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 23173-23183
-
-
Kim, J.A.1
Yeh, D.C.2
Ver, M.3
Li, Y.4
Carranza, A.5
Conrads, T.P.6
Veenstra, T.D.7
Harrington, M.A.8
Quon, M.J.9
-
20
-
-
9644268760
-
Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model
-
Kobayashi T, Taguchi K, Yasuhiro T, Matsumoto T, Kamata K. Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model. Hypertension 44: 956-962, 2004.
-
(2004)
Hypertension
, vol.44
, pp. 956-962
-
-
Kobayashi, T.1
Taguchi, K.2
Yasuhiro, T.3
Matsumoto, T.4
Kamata, K.5
-
21
-
-
77149175962
-
Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3
-
Kopp A, Buechler C, Bala M, Neumeier M, Scholmerich J, Schaffler A. Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3. Endocrinology 151: 1097-1108, 2010.
-
(2010)
Endocrinology
, vol.151
, pp. 1097-1108
-
-
Kopp, A.1
Buechler, C.2
Bala, M.3
Neumeier, M.4
Scholmerich, J.5
Schaffler, A.6
-
22
-
-
63049112908
-
Innate immunity and adipocyte function: Ligandspecific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes
-
Kopp A, Buechler C, Neumeier M, Weigert J, Aslanidis C, Scholmerich J, Schaffler A. Innate immunity and adipocyte function: ligandspecific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes. Obesity (Silver Spring) 17: 648-656, 2009.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 648-656
-
-
Kopp, A.1
Buechler, C.2
Neumeier, M.3
Weigert, J.4
Aslanidis, C.5
Scholmerich, J.6
Schaffler, A.7
-
23
-
-
79952142784
-
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle
-
Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T. Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab 13: 294-307, 2011.
-
(2011)
Cell Metab
, vol.13
, pp. 294-307
-
-
Kubota, T.1
Kubota, N.2
Kumagai, H.3
Yamaguchi, S.4
Kozono, H.5
Takahashi, T.6
Inoue, M.7
Itoh, S.8
Takamoto, I.9
Sasako, T.10
Kumagai, K.11
Kawai, T.12
Hashimoto, S.13
Kobayashi, T.14
Sato, M.15
Tokuyama, K.16
Nishimura, S.17
Tsunoda, M.18
Ide, T.19
Murakami, K.20
Yamazaki, T.21
Ezaki, O.22
Kawamura, K.23
Masuda, H.24
Moroi, M.25
Sugi, K.26
Oike, Y.27
Shimokawa, H.28
Yanagihara, N.29
Tsutsui, M.30
Terauchi, Y.31
Tobe, K.32
Nagai, R.33
Kamata, K.34
Inoue, K.35
Kodama, T.36
Ueki, K.37
Kadowaki, T.38
more..
-
24
-
-
79953653547
-
Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse
-
Kuo LH, Tsai PJ, Jiang MJ, Chuang YL, Yu L, Lai KT, Tsai YS. Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse. Diabetologia 54: 168-179, 2011.
-
(2011)
Diabetologia
, vol.54
, pp. 168-179
-
-
Kuo, L.H.1
Tsai, P.J.2
Jiang, M.J.3
Chuang, Y.L.4
Yu, L.5
Lai, K.T.6
Tsai, Y.S.7
-
25
-
-
75149162956
-
PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells
-
Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E, Willems F. PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells. Eur J Immunol 40: 505-515, 2010.
-
(2010)
Eur J Immunol
, vol.40
, pp. 505-515
-
-
Langlet, C.1
Springael, C.2
Johnson, J.3
Thomas, S.4
Flamand, V.5
Leitges, M.6
Goldman, M.7
Aksoy, E.8
Willems, F.9
-
26
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 276: 16683-16689, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
27
-
-
38949125499
-
Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice
-
Lee S, Muniyappa R, Yan X, Chen H, Yue LQ, Hong EG, Kim JK, Quon MJ. Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice. Am J Physiol Endocrinol Metab 294: E261-E270, 2008.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Lee, S.1
Muniyappa, R.2
Yan, X.3
Chen, H.4
Yue, L.Q.5
Hong, E.G.6
Kim, J.K.7
Quon, M.J.8
-
28
-
-
0037408393
-
Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment
-
Lim YC, Garcia-Cardena G, Allport JR, Zervoglos M, Connolly AJ, Gimbrone MA Jr, Luscinskas FW. Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment. Am J Pathol 162: 1591-1601, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 1591-1601
-
-
Lim, Y.C.1
Garcia-Cardena, G.2
Allport, J.R.3
Zervoglos, M.4
Connolly, A.J.5
Gimbrone Jr., M.A.6
Luscinskas, F.W.7
-
29
-
-
84863940277
-
Protein kinase C and toll-like receptor signaling
-
Loegering DJ, Lennartz MR. Protein kinase C and toll-like receptor signaling. Enzyme Res 2011: 537821, 2011.
-
(2011)
Enzyme Res
, vol.2011
, pp. 537821
-
-
Loegering, D.J.1
Lennartz, M.R.2
-
30
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F, Chen X, Lee AH, Glimcher LH. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol 11: 411-418, 2010.
-
(2010)
Nat Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
Glimcher, L.H.4
-
32
-
-
0033826624
-
Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects
-
Mott DM, Hoyt C, Caspari R, Stone K, Pratley R, Bogardus C. Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects. Am J Physiol Endocrinol Metab 279: E561-E569, 2000.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Mott, D.M.1
Hoyt, C.2
Caspari, R.3
Stone, K.4
Pratley, R.5
Bogardus, C.6
-
33
-
-
58149240784
-
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling
-
Moynagh PN. The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling. Trends Immunol 30: 33-42, 2009.
-
(2009)
Trends Immunol
, vol.30
, pp. 33-42
-
-
Moynagh, P.N.1
-
34
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 282: 35279-35292, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
35
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Gorgun CZ, Hotamisligil GS. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313: 1137-1140, 2006.
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
36
-
-
78650054500
-
Regulation of fasting fuel metabolism by toll-like receptor 4
-
Pang S, Tang H, Zhuo S, Zang YQ, Le Y. Regulation of fasting fuel metabolism by toll-like receptor 4. Diabetes 59: 3041-3048, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 3041-3048
-
-
Pang, S.1
Tang, H.2
Zhuo, S.3
Zang, Y.Q.4
Le, Y.5
-
37
-
-
0030669392
-
A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
-
Paz K, Hemi R, LeRoith D, Karasik A, Elhanany E, Kanety H, Zick Y. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 272: 29911-29918, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 29911-29918
-
-
Paz, K.1
Hemi, R.2
LeRoith, D.3
Karasik, A.4
Elhanany, E.5
Kanety, H.6
Zick, Y.7
-
38
-
-
33746234763
-
Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome
-
Picchi A, Gao X, Belmadani S, Potter BJ, Focardi M, Chilian WM, Zhang C. Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome. Circ Res 99: 69-77, 2006.
-
(2006)
Circ Res
, vol.99
, pp. 69-77
-
-
Picchi, A.1
Gao, X.2
Belmadani, S.3
Potter, B.J.4
Focardi, M.5
Chilian, W.M.6
Zhang, C.7
-
39
-
-
34247884376
-
C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
-
Poggi M, Bastelica D, Gual P, Iglesias MA, Gremeaux T, Knauf C, Peiretti F, Verdier M, Juhan-Vague I, Tanti JF, Burcelin R, Alessi MC. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 50: 1267-1276, 2007.
-
(2007)
Diabetologia
, vol.50
, pp. 1267-1276
-
-
Poggi, M.1
Bastelica, D.2
Gual, P.3
Iglesias, M.A.4
Gremeaux, T.5
Knauf, C.6
Peiretti, F.7
Verdier, M.8
Juhan-Vague, I.9
Tanti, J.F.10
Burcelin, R.11
Alessi, M.C.12
-
40
-
-
23744511665
-
Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production
-
Potenza MA, Marasciulo FL, Chieppa DM, Brigiani GS, Formoso G, Quon MJ, Montagnani M. Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production. Am J Physiol Heart Circ Physiol 289: H813-H822, 2005.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Potenza, M.A.1
Marasciulo, F.L.2
Chieppa, D.M.3
Brigiani, G.S.4
Formoso, G.5
Quon, M.J.6
Montagnani, M.7
-
41
-
-
33845516684
-
Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance
-
Potenza MA, Marasciulo FL, Tarquinio M, Quon MJ, Montagnani M. Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance. Diabetes 55: 3594-3603, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 3594-3603
-
-
Potenza, M.A.1
Marasciulo, F.L.2
Tarquinio, M.3
Quon, M.J.4
Montagnani, M.5
-
42
-
-
0036173913
-
QUICKI is a useful and accurate index of insulin sensitivity
-
Quon MJ. QUICKI is a useful and accurate index of insulin sensitivity. J Clin Endocrinol Metab 87: 949-951, 2002.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 949-951
-
-
Quon, M.J.1
-
43
-
-
77955292064
-
Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice
-
Rask-Madsen C, Li Q, Freund B, Feather D, Abramov R, Wu IH, Chen K, Yamamoto-Hiraoka J, Goldenbogen J, Sotiropoulos KB, Clermont A, Geraldes P, Dall'Osso C, Wagers AJ, Huang PL, Rekhter M, Scalia R, Kahn CR, King GL. Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice. Cell Metab 11: 379-389, 2010.
-
(2010)
Cell Metab
, vol.11
, pp. 379-389
-
-
Rask-Madsen, C.1
Li, Q.2
Freund, B.3
Feather, D.4
Abramov, R.5
Wu, I.H.6
Chen, K.7
Yamamoto-Hiraoka, J.8
Goldenbogen, J.9
Sotiropoulos, K.B.10
Clermont, A.11
Geraldes, P.12
Dall'Osso, C.13
Wagers, A.J.14
Huang, P.L.15
Rekhter, M.16
Scalia, R.17
Kahn, C.R.18
King, G.L.19
-
44
-
-
77950909714
-
Reduced NO-cGMP signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding
-
Rizzo NO, Maloney E, Pham M, Luttrell I, Wessells H, Tateya S, Daum G, Handa P, Schwartz MW, Kim F. Reduced NO-cGMP signaling contributes to vascular inflammation and insulin resistance induced by high-fat feeding. Arterioscler Thromb Vasc Biol 30: 758-765, 2010.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 758-765
-
-
Rizzo, N.O.1
Maloney, E.2
Pham, M.3
Luttrell, I.4
Wessells, H.5
Tateya, S.6
Daum, G.7
Handa, P.8
Schwartz, M.W.9
Kim, F.10
-
47
-
-
77958532945
-
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
-
Seimon TA, Nadolski MJ, Liao X, Magallon J, Nguyen M, Feric NT, Koschinsky ML, Harkewicz R, Witztum JL, Tsimikas S, Golenbock D, Moore KJ, Tabas I. Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab 12: 467-482, 2010.
-
(2010)
Cell Metab
, vol.12
, pp. 467-482
-
-
Seimon, T.A.1
Nadolski, M.J.2
Liao, X.3
Magallon, J.4
Nguyen, M.5
Feric, N.T.6
Koschinsky, M.L.7
Harkewicz, R.8
Witztum, J.L.9
Tsimikas, S.10
Golenbock, D.11
Moore, K.J.12
Tabas, I.13
-
48
-
-
33748755008
-
Toll-like receptor-2 is essential for the development of palmitateinduced insulin resistance in myotubes
-
Senn JJ. Toll-like receptor-2 is essential for the development of palmitateinduced insulin resistance in myotubes. J Biol Chem 281: 26865-26875, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 26865-26875
-
-
Senn, J.J.1
-
49
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116: 3015-3025, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
50
-
-
48749088352
-
Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages
-
Shin DM, Yang CS, Lee JY, Lee SJ, Choi HH, Lee HM, Yuk JM, Harding CV, Jo EK. Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages. Cell Microbiol 10: 1893-1905, 2008.
-
(2008)
Cell Microbiol
, vol.10
, pp. 1893-1905
-
-
Shin, D.M.1
Yang, C.S.2
Lee, J.Y.3
Lee, S.J.4
Choi, H.H.5
Lee, H.M.6
Yuk, J.M.7
Harding, C.V.8
Jo, E.K.9
-
51
-
-
65649147143
-
Innate immunity, Toll-like receptors, and atherosclerosis: Mouse models and methods
-
Sorrentino R, Arditi M. Innate immunity, Toll-like receptors, and atherosclerosis: mouse models and methods. Methods Mol Biol 517: 381-399, 2009.
-
(2009)
Methods Mol Biol
, vol.517
, pp. 381-399
-
-
Sorrentino, R.1
Arditi, M.2
-
52
-
-
0028030813
-
Insulinmediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
-
Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulinmediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 94: 1172-1179, 1994.
-
(1994)
J Clin Invest
, vol.94
, pp. 1172-1179
-
-
Steinberg, H.O.1
Brechtel, G.2
Johnson, A.3
Fineberg, N.4
Baron, A.D.5
-
53
-
-
0029977757
-
Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
-
Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 97: 2601-2610, 1996.
-
(1996)
J Clin Invest
, vol.97
, pp. 2601-2610
-
-
Steinberg, H.O.1
Chaker, H.2
Leaming, R.3
Johnson, A.4
Brechtel, G.5
Baron, A.D.6
-
54
-
-
70350435712
-
Macrophage apoptosis in advanced atherosclerosis
-
Tabas I, Seimon T, Timmins J, Li G, Lim W. Macrophage apoptosis in advanced atherosclerosis. Ann NY Acad Sci 1173, Suppl 1: E40-E45, 2009.
-
(2009)
Ann NY Acad Sci
, vol.1173
, Issue.SUPPL. 1
-
-
Tabas, I.1
Seimon, T.2
Timmins, J.3
Li, G.4
Lim, W.5
-
55
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents dietinduced obesity and insulin resistance
-
Tsukumo DM, Carvalho-Filho MA, Carvalheira JB, Prada PO, Hirabara SM, Schenka AA, Araujo EP, Vassallo J, Curi R, Velloso LA, Saad MJ. Loss-of-function mutation in Toll-like receptor 4 prevents dietinduced obesity and insulin resistance. Diabetes 56: 1986-1998, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.3
Prada, P.O.4
Hirabara, S.M.5
Schenka, A.A.6
Araujo, E.P.7
Vassallo, J.8
Curi, R.9
Velloso, L.A.10
Saad, M.J.11
-
56
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389: 610-614, 1997.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
57
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ. Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101: 1539-1545, 2000.
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
Cong, L.N.4
Kirby, M.5
Mostowski, H.6
Quon, M.J.7
-
58
-
-
0029789432
-
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
-
Zeng G, Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J Clin Invest 98: 894-898, 1996.
-
(1996)
J Clin Invest
, vol.98
, pp. 894-898
-
-
Zeng, G.1
Quon, M.J.2
-
59
-
-
31544440725
-
Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles
-
Zhang C, Hein TW, Wang W, Ren Y, Shipley RD, Kuo L. Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles. J Mol Cell Cardiol 40: 247-257, 2006.
-
(2006)
J Mol Cell Cardiol
, vol.40
, pp. 247-257
-
-
Zhang, C.1
Hein, T.W.2
Wang, W.3
Ren, Y.4
Shipley, R.D.5
Kuo, L.6
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