Sulfur-containing amino acids in 7TMRs: Molecular gears for pharmacology and function

Trends in Pharmacological Sciences

Volumn 34, Issue 6, 2013, Pages 320-331

  Cordomí, Arnau ^a   Gómez Tamayo, José C ^a   Gigoux, Véronique ^b   Fourmy, Daniel ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

crystal structure; GPCR; molecular modeling; site directed mutagenesis

Indexed keywords

ADENOSINE A2A RECEPTOR; ANGIOTENSIN 1 RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CHEMOKINE RECEPTOR CX3CR1; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CYSTEINE; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; METHIONINE; RHODOPSIN; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SULFUR AMINO ACID; THYROTROPIN RECEPTOR;

ALLOSTERISM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DISULFIDE BOND; HUMAN; HYDROGEN BOND; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; REVIEW; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACIDS, SULFUR; ANIMALS; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84878558448     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2013.03.008     Document Type: Review

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