메뉴 건너뛰기




Volumn 109, Issue 7, 2013, Pages 1704-1712

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

Author keywords

Capsaicin; Dorsal root ganglion; Sodium channel

Indexed keywords

CAPSAICIN; ION CHANNEL; LIDOCAINE ETHOBROMIDE; PANNEXIN CHANNEL; SODIUM ION; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

EID: 84878507220     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00012.2013     Document Type: Article
Times cited : (73)

References (51)
  • 1
    • 0019821241 scopus 로고
    • Block of endplate channels by permeant cations in frog skeletal muscle
    • Adams DJ, Nonner W, Dwyer TM, Hille B. Block of endplate channels by permeant cations in frog skeletal muscle. J Gen Physiol 78: 593-615, 1981.
    • (1981) J Gen Physiol , vol.78 , pp. 593-615
    • Adams, D.J.1    Nonner, W.2    Dwyer, T.M.3    Hille, B.4
  • 2
    • 0036901847 scopus 로고    scopus 로고
    • Voltage-dependent priming of rat vanilloid receptor: Effects of agonist and protein kinase C activation
    • Ahern GP, Premkumar LS. Voltage-dependent priming of rat vanilloid receptor: effects of agonist and protein kinase C activation. J Physiol 545: 441-451, 2002.
    • (2002) J Physiol , vol.545 , pp. 441-451
    • Ahern, G.P.1    Premkumar, L.S.2
  • 3
    • 33646845297 scopus 로고    scopus 로고
    • Polyamines are potent ligands for the capsaicin receptor TRPV1
    • Ahern GP, Wang X, Miyares RL. Polyamines are potent ligands for the capsaicin receptor TRPV1. J Biol Chem 281: 8991-8995, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 8991-8995
    • Ahern, G.P.1    Wang, X.2    Miyares, R.L.3
  • 4
    • 77952650740 scopus 로고    scopus 로고
    • Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation
    • Banke TG, Chaplan SR, Wickenden AD. Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am J Physiol Cell Physiol 298: C1457-C1468, 2010.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Banke, T.G.1    Chaplan, S.R.2    Wickenden, A.D.3
  • 5
    • 34948819283 scopus 로고    scopus 로고
    • Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
    • Binshtok AM, Bean BP, Woolf CJ. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature 449: 607-610, 2007.
    • (2007) Nature , vol.449 , pp. 607-610
    • Binshtok, A.M.1    Bean, B.P.2    Woolf, C.J.3
  • 7
    • 0028832290 scopus 로고
    • Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties
    • Cardenas CG, Del Mar LP, Scroggs RS. Variation in serotonergic inhibition of calcium channel currents in four types of rat sensory neurons differentiated by membrane properties. J Neurophysiol 74: 1870-1879, 1995.
    • (1995) J Neurophysiol , vol.74 , pp. 1870-1879
    • Cardenas, C.G.1    Del Mar, L.P.2    Scroggs, R.S.3
  • 8
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: A molecular gateway to the pain pathway
    • Caterina MJ, Julius D. The vanilloid receptor: a molecular gateway to the pain pathway. Annu Rev Neurosci 24: 487-517, 2001.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 11
    • 42649095142 scopus 로고    scopus 로고
    • TRPV1 shows dynamic ionic selectivity during agonist stimulation
    • Chung MK, Güler AD, Caterina MJ. TRPV1 shows dynamic ionic selectivity during agonist stimulation. Nat Neurosci 11: 555-564, 2008.
    • (2008) Nat Neurosci , vol.11 , pp. 555-564
    • Chung, M.K.1    Güler, A.D.2    Caterina, M.J.3
  • 12
    • 1342323323 scopus 로고    scopus 로고
    • Mitogenactivated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells
    • Donnelly-Roberts DL, Namovic MT, Faltynek CR, Jarvis MF. Mitogenactivated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells. J Pharmacol Exp Ther 308: 1053-1061, 2004.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 1053-1061
    • Donnelly-Roberts, D.L.1    Namovic, M.T.2    Faltynek, C.R.3    Jarvis, M.F.4
  • 13
    • 0018826901 scopus 로고
    • The permeability of the endplate channel to organic cations in frog muscle
    • Dwyer TM, Adams DJ, Hille B. The permeability of the endplate channel to organic cations in frog muscle. J Gen Physiol 75: 469-492, 1980.
    • (1980) J Gen Physiol , vol.75 , pp. 469-492
    • Dwyer, T.M.1    Adams, D.J.2    Hille, B.3
  • 14
    • 77953871931 scopus 로고    scopus 로고
    • Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells
    • Faria RX, Cascabulho CM, Reis RA, Alves LA. Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells. Naunyn Schmiedebergs Arch Pharmacol 382: 73-87, 2010.
    • (2010) Naunyn Schmiedebergs Arch Pharmacol , vol.382 , pp. 73-87
    • Faria, R.X.1    Cascabulho, C.M.2    Reis, R.A.3    Alves, L.A.4
  • 15
    • 4444357289 scopus 로고    scopus 로고
    • Probing the pore of the auditory hair cell mechanotransducer channel in turtle
    • Farris HE, LeBlanc CL, Goswami J, Ricci AJ. Probing the pore of the auditory hair cell mechanotransducer channel in turtle. J Physiol 558: 769-792, 2004.
    • (2004) J Physiol , vol.558 , pp. 769-792
    • Farris, H.E.1    Leblanc, C.L.2    Goswami, J.3    Ricci, A.J.4
  • 16
    • 70349560369 scopus 로고    scopus 로고
    • Defining features of the hair cell mechanoelectrical transducer channel
    • Fettiplace R. Defining features of the hair cell mechanoelectrical transducer channel. Pflügers Arch 458: 1115-1123, 2009.
    • (2009) Pflügers Arch , vol.458 , pp. 1115-1123
    • Fettiplace, R.1
  • 17
    • 0014704033 scopus 로고
    • The site of action and active form of local anesthetics. II. Experiments with quaternary compounds
    • Frazier DT, Narahashi T, Yamada M. The site of action and active form of local anesthetics. II. Experiments with quaternary compounds. J Pharmacol Exp Ther 171: 45-51, 1970.
    • (1970) J Pharmacol Exp Ther , vol.171 , pp. 45-51
    • Frazier, D.T.1    Narahashi, T.2    Yamada, M.3
  • 18
  • 20
    • 0019176153 scopus 로고
    • Asymmetry of the acetylcholine channel revealed by quaternary anesthetics
    • Horn R, Brodwick MS, Dickey WD. Asymmetry of the acetylcholine channel revealed by quaternary anesthetics. Science 210: 205-207, 1980.
    • (1980) Science , vol.210 , pp. 205-207
    • Horn, R.1    Brodwick, M.S.2    Dickey, W.D.3
  • 21
    • 59449083489 scopus 로고    scopus 로고
    • Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums
    • Jara-Oseguera A, Llorente I, Rosenbaum T, Islas LD. Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums. J Gen Physiol 132: 547-562, 2008.
    • (2008) J Gen Physiol , vol.132 , pp. 547-562
    • Jara-Oseguera, A.1    Llorente, I.2    Rosenbaum, T.3    Islas, L.D.4
  • 22
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius D, Basbaum AI. Molecular mechanisms of nociception. Nature 413: 203-210, 2001.
    • (2001) Nature , vol.413 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 26
    • 84865279306 scopus 로고    scopus 로고
    • TRPA1 mediates mechanical sensitization in nociceptors during inflammation
    • Lennertz RC, Kossyreva EA, Smith AK, Stucky CL. TRPA1 mediates mechanical sensitization in nociceptors during inflammation. PLoS One 7: e43597, 2012.
    • (2012) PLoS One , vol.7
    • Lennertz, R.C.1    Kossyreva, E.A.2    Smith, A.K.3    Stucky, C.L.4
  • 27
    • 84555205265 scopus 로고    scopus 로고
    • Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensoryspecific analgesic effects
    • Liu H, Zhang HX, Hou HY, Lu XF, Wei JQ, Wang CG, Zhang LC, Zeng YM, Wu YP, Cao JL. Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensoryspecific analgesic effects. PLoS One 6: e29395, 2011.
    • (2011) PLoS One , vol.6
    • Liu, H.1    Zhang, H.X.2    Hou, H.Y.3    Lu, X.F.4    Wei, J.Q.5    Wang, C.G.6    Zhang, L.C.7    Zeng, Y.M.8    Wu, Y.P.9    Cao, J.L.10
  • 28
    • 36649016621 scopus 로고    scopus 로고
    • Voltage is a partial activator of rat thermosensitive TRP channels
    • Matta JA, Ahern GP. Voltage is a partial activator of rat thermosensitive TRP channels. J Physiol 585: 469-482, 2007.
    • (2007) J Physiol , vol.585 , pp. 469-482
    • Matta, J.A.1    Ahern, G.P.2
  • 30
    • 17144397173 scopus 로고    scopus 로고
    • 2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase
    • 2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase. J Biol Chem 280: 13424-13432, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 13424-13432
    • Mohapatra, D.P.1    Nau, C.2
  • 32
    • 0026687922 scopus 로고
    • Correction for liquid junction potentials in patch clamp experiments
    • Neher E. Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol 207: 123-131, 1992.
    • (1992) Methods Enzymol , vol.207 , pp. 123-131
    • Neher, E.1
  • 33
    • 0017905087 scopus 로고
    • Local anaesthetics transiently block currents through single acetylcholine-receptor channels
    • Neher E, Steinbach JH. Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J Physiol 277: 153-176, 1978.
    • (1978) J Physiol , vol.277 , pp. 153-176
    • Neher, E.1    Steinbach, J.H.2
  • 37
    • 0031772578 scopus 로고    scopus 로고
    • Delimiting the binding site for quaternary ammonium lidocaine derivatives in the acetylcholine receptor channel
    • Pascual JM, Karlin A. Delimiting the binding site for quaternary ammonium lidocaine derivatives in the acetylcholine receptor channel. J Gen Physiol 112: 611-621, 1998.
    • (1998) J Gen Physiol , vol.112 , pp. 611-621
    • Pascual, J.M.1    Karlin, A.2
  • 38
    • 33750473352 scopus 로고    scopus 로고
    • Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
    • Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J 25: 5071-5082, 2006.
    • (2006) EMBO J , vol.25 , pp. 5071-5082
    • Pelegrin, P.1    Surprenant, A.2
  • 39
    • 0033739591 scopus 로고    scopus 로고
    • Subclassified acutely dissociated cells of rat DRG: Histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents
    • Petruska JC, Napaporn J, Johnson RD, Gu JG, Cooper BY. Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents. J Neurophysiol 84: 2365-2379, 2000.
    • (2000) J Neurophysiol , vol.84 , pp. 2365-2379
    • Petruska, J.C.1    Napaporn, J.2    Johnson, R.D.3    Gu, J.G.4    Cooper, B.Y.5
  • 40
    • 0037112377 scopus 로고    scopus 로고
    • Single-channel properties of native and cloned rat vanilloid receptors
    • Premkumar LS, Agarwal S, Steffen D. Single-channel properties of native and cloned rat vanilloid receptors. J Physiol 545: 107-117, 2002.
    • (2002) J Physiol , vol.545 , pp. 107-117
    • Premkumar, L.S.1    Agarwal, S.2    Steffen, D.3
  • 41
    • 85027936054 scopus 로고    scopus 로고
    • The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro
    • Rivera-Acevedo RE, Pless SA, Ahern CA, Schwarz SK. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology 114: 1425-1434, 2011.
    • (2011) Anesthesiology , vol.114 , pp. 1425-1434
    • Rivera-Acevedo, R.E.1    Pless, S.A.2    Ahern, C.A.3    Schwarz, S.K.4
  • 42
    • 84869808324 scopus 로고    scopus 로고
    • Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes
    • Rivera-Acevedo RE, Pless SA, Schwarz SK, Ahern CA. Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes. Mol Pharmacol 82: 1129-1135, 2012.
    • (2012) Mol Pharmacol , vol.82 , pp. 1129-1135
    • Rivera-Acevedo, R.E.1    Pless, S.A.2    Schwarz, S.K.3    Ahern, C.A.4
  • 43
    • 79960180415 scopus 로고    scopus 로고
    • Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: A systematic study and review
    • Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ. Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. Br J Pharmacol 164: 48-58, 2011.
    • (2011) Br J Pharmacol , vol.164 , pp. 48-58
    • Roberson, D.P.1    Binshtok, A.M.2    Blasl, F.3    Bean, B.P.4    Woolf, C.J.5
  • 44
    • 0015784454 scopus 로고
    • The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine
    • Strichartz GR. The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J Gen Physiol 62: 37-57, 1973.
    • (1973) J Gen Physiol , vol.62 , pp. 37-57
    • Strichartz, G.R.1
  • 47
    • 4043077669 scopus 로고    scopus 로고
    • The principle of temperature-dependent gating in coldand heat-sensitive TRP channels
    • Voets T, Droogmans G, Wissenbach U, Janssens A, Flockerzi V, Nilius B. The principle of temperature-dependent gating in coldand heat-sensitive TRP channels. Nature 430: 748-754, 2004.
    • (2004) Nature , vol.430 , pp. 748-754
    • Voets, T.1    Droogmans, G.2    Wissenbach, U.3    Janssens, A.4    Flockerzi, V.5    Nilius, B.6
  • 48
    • 34547184022 scopus 로고    scopus 로고
    • Nociceptors-noxious stimulus detectors
    • Woolf CJ, Ma Q. Nociceptors-noxious stimulus detectors. Neuron 55: 353-364, 2007.
    • (2007) Neuron , vol.55 , pp. 353-364
    • Woolf, C.J.1    Ma, Q.2
  • 49
    • 24044532892 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated calcium channels through calciumdependent calcineurin in sensory neurons
    • Wu ZZ, Chen SR, Pan HL. Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated calcium channels through calciumdependent calcineurin in sensory neurons. J Biol Chem 280: 18142-18151, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 18142-18151
    • Wu, Z.Z.1    Chen, S.R.2    Pan, H.L.3
  • 50
    • 77958530854 scopus 로고    scopus 로고
    • Experimental characterization and mathematical modeling of P2X7 receptor channel gating
    • Yan Z, Khadra A, Li S, Tomic M, Sherman A, Stojilkovic SS. Experimental characterization and mathematical modeling of P2X7 receptor channel gating. J Neurosci 30: 14213-14224, 2010.
    • (2010) J Neurosci , vol.30 , pp. 14213-14224
    • Yan, Z.1    Khadra, A.2    Li, S.3    Tomic, M.4    Sherman, A.5    Stojilkovic, S.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.