The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons

Journal of Clinical Investigation

Volumn 118, Issue 2, 2008, Pages 763-776

  Leffler, Andreas ^a   Fischer, Michael J ^a   Rehner, Dietlinde ^a   Kienel, Stephanie ^a   Kistner, Katrin ^a   Sauer, Susanne K ^a   Gavva, Narender R ^b   Reeh, Peter W ^a   Nau, Carla ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; LIDOCAINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; DEPLETION; EXCITATION; LOCAL ANESTHESIA; MOUSE; NEUROGENIC INFLAMMATION; NEUROTOXICITY; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SECRETION; SENSITIVITY ANALYSIS; SENSORY NERVE CELL; SKIN; SPINAL GANGLION;

ANESTHETICS, LOCAL; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CALCIUM CHANNELS; CAPSAICIN; CELL LINE; EVOKED POTENTIALS; HUMANS; LIDOCAINE; NEURONS, AFFERENT; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SENSORY SYSTEM AGENTS; TRPV CATION CHANNELS;

EID: 38849094740     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI32751     Document Type: Article

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