Activation of CaMKII and ERK1/2 contributes to the time-dependent potentiation of Ca2+ response elicited by repeated application of capsaicin in rat DRG neurons

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 300, Issue 3, 2011, Pages

  Zhang, Xiulin ^a   Daugherty, Stephanie L ^a   de Groat, William C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium calmodulin dependent protein kinase II; Capsaicin; Dorsal root ganglion; Extracellular signal regulated kinase; Nociceptor; Rat; Sensitization

Indexed keywords

CALCINEURIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; CAPSAICIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DELTAMETHRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PROTEIN KINASE C; TACHYKININ RECEPTOR; VANILLOID RECEPTOR 1;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; INTRACELLULAR SIGNALING; LONG TERM POTENTIATION; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; SPINAL GANGLION; TACHYPHYLAXIS;

ANIMALS; BENZYLAMINES; BUTADIENES; CALCIUM SIGNALING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CAPSAICIN; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GANGLIA, SPINAL; MALE; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONAL PLASTICITY; NEURONS; NITRILES; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PYRETHRINS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SENSORY SYSTEM AGENTS; SUBSTANCE P; SULFONAMIDES; TACHYPHYLAXIS; TIME FACTORS; TRPV CATION CHANNELS;

EID: 79954497031     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00672.2010     Document Type: Article

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