-
1
-
-
0029071657
-
D-type cyclins
-
Sherr CJ, (1995) D-type cyclins. Trends Biochem Sci 20: 187-190.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 187-190
-
-
Sherr, C.J.1
-
2
-
-
0030561571
-
The retinoblastoma protein pathway and the restriction point
-
Bartek J, Bartkova J, Lukas J, (1996) The retinoblastoma protein pathway and the restriction point. Curr Opin Cell Biol 8: 805-814.
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 805-814
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
3
-
-
34248380561
-
Regulation of CDK4
-
Bockstaele L, Coulonval K, Kooken H, Paternot S, Roger PP, (2006) Regulation of CDK4. Cell Division 1: 25.
-
(2006)
Cell Division
, vol.1
, pp. 25
-
-
Bockstaele, L.1
Coulonval, K.2
Kooken, H.3
Paternot, S.4
Roger, P.P.5
-
4
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
Lundberg AS, Weinberg RA, (1998) Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol Cell Biol 18: 753-761.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 753-761
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
5
-
-
43149108161
-
A bistable Rb-E2F switch underlies the restriction point
-
Yao G, Lee TJ, Mori S, Nevins JR, You L, (2008) A bistable Rb-E2F switch underlies the restriction point. Nat Cell Biol 10: 476-482.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 476-482
-
-
Yao, G.1
Lee, T.J.2
Mori, S.3
Nevins, J.R.4
You, L.5
-
6
-
-
0033564697
-
CDK inhibitors: positive and negative regulators of G1-phase progression
-
Sherr CJ, Roberts JM, (1999) CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13: 1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
7
-
-
18344369616
-
Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues
-
Pei XH, Xiong Y, (2005) Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues. Oncogene 24: 2787-2795.
-
(2005)
Oncogene
, vol.24
, pp. 2787-2795
-
-
Pei, X.H.1
Xiong, Y.2
-
8
-
-
67649424560
-
p21 in cancer: intricate networks and multiple activities
-
Abbas T, Dutta A, (2009) p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 9: 400-414.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 400-414
-
-
Abbas, T.1
Dutta, A.2
-
9
-
-
0032535375
-
Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)
-
Hengst L, Gopfert U, Lashuel HA, Reed SI, (1998) Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1). Genes Dev 12: 3882-3888.
-
(1998)
Genes Dev
, vol.12
, pp. 3882-3888
-
-
Hengst, L.1
Gopfert, U.2
Lashuel, H.A.3
Reed, S.I.4
-
10
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
LaBaer J, Garrett MD, Stevenson LF, Slingerland JM, Sandhu C, et al. (1997) New functional activities for the p21 family of CDK inhibitors. Genes Dev 11: 847-862.
-
(1997)
Genes Dev
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
-
11
-
-
0030845187
-
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4
-
Blain SW, Montalvo E, Massague J, (1997) Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. J Biol Chem 272: 25863-25872.
-
(1997)
J Biol Chem
, vol.272
, pp. 25863-25872
-
-
Blain, S.W.1
Montalvo, E.2
Massague, J.3
-
12
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE, (1997) Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev 11: 1464-1478.
-
(1997)
Genes Dev
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
13
-
-
33846321913
-
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
-
Grimmler M, Wang Y, Mund T, Cilensek Z, Keidel EM, et al. (2007) Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell 128: 269-280.
-
(2007)
Cell
, vol.128
, pp. 269-280
-
-
Grimmler, M.1
Wang, Y.2
Mund, T.3
Cilensek, Z.4
Keidel, E.M.5
-
14
-
-
33846268807
-
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2
-
Chu I, Sun J, Arnaout A, Kahn H, Hanna W, et al. (2007) p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2. Cell 128: 281-294.
-
(2007)
Cell
, vol.128
, pp. 281-294
-
-
Chu, I.1
Sun, J.2
Arnaout, A.3
Kahn, H.4
Hanna, W.5
-
15
-
-
59449106702
-
p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes
-
Ray A, James MK, Larochelle S, Fisher RP, Blain SW, (2009) p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes. Mol Cell Biol 29: 986-999.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 986-999
-
-
Ray, A.1
James, M.K.2
Larochelle, S.3
Fisher, R.P.4
Blain, S.W.5
-
16
-
-
84860168892
-
Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1)
-
Ou L, Waddell MB, Kriwacki RW, (2012) Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1). ACS Chem Biol 7: 678-682.
-
(2012)
ACS Chem Biol
, vol.7
, pp. 678-682
-
-
Ou, L.1
Waddell, M.B.2
Kriwacki, R.W.3
-
17
-
-
84861371005
-
Regulation of p27 (Kip1) by mitogen-induced tyrosine phosphorylation
-
Jakel H, Peschel I, Kunze C, Weinl C, Hengst L, (2012) Regulation of p27 (Kip1) by mitogen-induced tyrosine phosphorylation. Cell Cycle 11: 1910-1917.
-
(2012)
Cell Cycle
, vol.11
, pp. 1910-1917
-
-
Jakel, H.1
Peschel, I.2
Kunze, C.3
Weinl, C.4
Hengst, L.5
-
18
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr CJ, McCormick F, (2002) The RB and p53 pathways in cancer. Cancer Cell 2: 103-112.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
19
-
-
79960836823
-
Cyclin D as a therapeutic target in cancer
-
Musgrove EA, Caldon CE, Barraclough J, Stone A, Sutherland RL, (2011) Cyclin D as a therapeutic target in cancer. Nat Rev Cancer 11: 558-572.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 558-572
-
-
Musgrove, E.A.1
Caldon, C.E.2
Barraclough, J.3
Stone, A.4
Sutherland, R.L.5
-
20
-
-
4444307411
-
Mouse development and cell proliferation in the absence of D-cyclins
-
Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, et al. (2004) Mouse development and cell proliferation in the absence of D-cyclins. Cell 118: 477-491.
-
(2004)
Cell
, vol.118
, pp. 477-491
-
-
Kozar, K.1
Ciemerych, M.A.2
Rebel, V.I.3
Shigematsu, H.4
Zagozdzon, A.5
-
21
-
-
4344631708
-
Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues
-
Miliani de Marval PL, Macias E, Rounbehler R, Sicinski P, Kiyokawa H, et al. (2004) Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Mol Cell Biol 24: 7538-7547.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7538-7547
-
-
Miliani de Marval, P.L.1
Macias, E.2
Rounbehler, R.3
Sicinski, P.4
Kiyokawa, H.5
-
22
-
-
0036965836
-
Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation
-
Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, et al. (2002) Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. Am J Pathol 161: 405-411.
-
(2002)
Am J Pathol
, vol.161
, pp. 405-411
-
-
Rodriguez-Puebla, M.L.1
Miliani de Marval, P.L.2
LaCava, M.3
Moons, D.S.4
Kiyokawa, H.5
-
23
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
Malumbres M, Barbacid M, (2009) Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 9: 153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
24
-
-
77954279920
-
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma
-
Puyol M, Martin A, Dubus P, Mulero F, Pizcueta P, et al. (2010) A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma. Cancer Cell 18: 63-73.
-
(2010)
Cancer Cell
, vol.18
, pp. 63-73
-
-
Puyol, M.1
Martin, A.2
Dubus, P.3
Mulero, F.4
Pizcueta, P.5
-
25
-
-
84867618851
-
The requirement for cyclin D function in tumor maintenance
-
Choi YJ, Li X, Hydbring P, Sanda T, Stefano J, et al. (2012) The requirement for cyclin D function in tumor maintenance. Cancer Cell 22: 438-451.
-
(2012)
Cancer Cell
, vol.22
, pp. 438-451
-
-
Choi, Y.J.1
Li, X.2
Hydbring, P.3
Sanda, T.4
Stefano, J.5
-
26
-
-
34548838818
-
Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia
-
Wang L, Wang J, Blaser BW, Duchemin AM, Kusewitt DF, et al. (2007) Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia. Blood 110: 2075-2083.
-
(2007)
Blood
, vol.110
, pp. 2075-2083
-
-
Wang, L.1
Wang, J.2
Blaser, B.W.3
Duchemin, A.M.4
Kusewitt, D.F.5
-
27
-
-
33747872306
-
A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6
-
Baughn LB, Di Liberto M, Wu K, Toogood PL, Louie T, et al. (2006) A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6. Cancer Res 66: 7661-7667.
-
(2006)
Cancer Res
, vol.66
, pp. 7661-7667
-
-
Baughn, L.B.1
Di Liberto, M.2
Wu, K.3
Toogood, P.L.4
Louie, T.5
-
28
-
-
77951082119
-
Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts
-
Michaud K, Solomon DA, Oermann E, Kim JS, Zhong WZ, et al. (2010) Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts. Cancer Res 70: 3228-3238.
-
(2010)
Cancer Res
, vol.70
, pp. 3228-3238
-
-
Michaud, K.1
Solomon, D.A.2
Oermann, E.3
Kim, J.S.4
Zhong, W.Z.5
-
29
-
-
84859079523
-
Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
-
Roberts PJ, Bisi JE, Strum JC, Combest AJ, Darr DB, et al. (2012) Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy. J Natl Cancer Inst 104: 476-487.
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 476-487
-
-
Roberts, P.J.1
Bisi, J.E.2
Strum, J.C.3
Combest, A.J.4
Darr, D.B.5
-
30
-
-
0028270189
-
Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
-
Kato JY, Matsuoka M, Strom DK, Sherr CJ, (1994) Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol Cell Biol 14: 2713-2721.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2713-2721
-
-
Kato, J.Y.1
Matsuoka, M.2
Strom, D.K.3
Sherr, C.J.4
-
31
-
-
33745470981
-
Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"
-
Bockstaele L, Kooken H, Libert F, Paternot S, Dumont JE, et al. (2006) Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". Mol Cell Biol 26: 5070-5085.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5070-5085
-
-
Bockstaele, L.1
Kooken, H.2
Libert, F.3
Paternot, S.4
Dumont, J.E.5
-
32
-
-
0031686960
-
Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities
-
Kaldis P, Russo AA, Chou HS, Pavletich NP, Solomon MJ, (1998) Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities. Mol Biol Cell 9: 2545-2560.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2545-2560
-
-
Kaldis, P.1
Russo, A.A.2
Chou, H.S.3
Pavletich, N.P.4
Solomon, M.J.5
-
33
-
-
67651233668
-
Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation
-
Bockstaele L, Bisteau X, Paternot S, Roger PP, (2009) Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation. Mol Cell Biol 29: 4188-4200.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4188-4200
-
-
Bockstaele, L.1
Bisteau, X.2
Paternot, S.3
Roger, P.P.4
-
34
-
-
18344381018
-
Cyclin E in normal and neoplastic cell cycles
-
Hwang HC, Clurman BE, (2005) Cyclin E in normal and neoplastic cell cycles. Oncogene 24: 2776-2786.
-
(2005)
Oncogene
, vol.24
, pp. 2776-2786
-
-
Hwang, H.C.1
Clurman, B.E.2
-
35
-
-
77953153764
-
Rb inactivation in cell cycle and cancer: The puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase
-
Paternot S, Bockstaele L, Bisteau X, Kooken H, Coulonval K, et al. (2010) Rb inactivation in cell cycle and cancer: The puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase. Cell Cycle 9: 689-699.
-
(2010)
Cell Cycle
, vol.9
, pp. 689-699
-
-
Paternot, S.1
Bockstaele, L.2
Bisteau, X.3
Kooken, H.4
Coulonval, K.5
-
36
-
-
58149306363
-
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation
-
Rocha AS, Paternot S, Coulonval K, Dumont JE, Soares P, et al. (2008) Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation. Mol Biol Cell 19: 4814-4825.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4814-4825
-
-
Rocha, A.S.1
Paternot, S.2
Coulonval, K.3
Dumont, J.E.4
Soares, P.5
-
37
-
-
66349086978
-
Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation
-
Paternot S, Roger PP, (2009) Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation. Cancer Res 69: 4577-4581.
-
(2009)
Cancer Res
, vol.69
, pp. 4577-4581
-
-
Paternot, S.1
Roger, P.P.2
-
38
-
-
77954830905
-
Cyclic AMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4
-
Blancquaert S, Wang L, Paternot S, Coulonval K, Dumont JE, et al. (2010) Cyclic AMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4. Mol Endocrinol 24: 1453-1468.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1453-1468
-
-
Blancquaert, S.1
Wang, L.2
Paternot, S.3
Coulonval, K.4
Dumont, J.E.5
-
39
-
-
0038036033
-
Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells
-
Paternot S, Coulonval K, Dumont JE, Roger PP, (2003) Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells. J Biol Chem 278: 26533-26540.
-
(2003)
J Biol Chem
, vol.278
, pp. 26533-26540
-
-
Paternot, S.1
Coulonval, K.2
Dumont, J.E.3
Roger, P.P.4
-
40
-
-
0346101798
-
Phosphorylations of cyclin-dependent kinase 2 revisited using two-dimensional gel electrophoresis
-
Coulonval K, Bockstaele L, Paternot S, Roger PP, (2003) Phosphorylations of cyclin-dependent kinase 2 revisited using two-dimensional gel electrophoresis. J Biol Chem 278: 52052-52060.
-
(2003)
J Biol Chem
, vol.278
, pp. 52052-52060
-
-
Coulonval, K.1
Bockstaele, L.2
Paternot, S.3
Roger, P.P.4
-
41
-
-
80655149445
-
Coupling of T161 and T14 phosphorylations protects cyclin B-CDK1 from premature activation
-
Coulonval K, Kooken H, Roger PP, (2011) Coupling of T161 and T14 phosphorylations protects cyclin B-CDK1 from premature activation. Mol Biol Cell 22: 3971-3985.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3971-3985
-
-
Coulonval, K.1
Kooken, H.2
Roger, P.P.3
-
42
-
-
0027994603
-
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase
-
Fisher RP, Morgan DO, (1994) A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase. Cell 78: 713-724.
-
(1994)
Cell
, vol.78
, pp. 713-724
-
-
Fisher, R.P.1
Morgan, D.O.2
-
43
-
-
0028807103
-
Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase
-
Fisher RP, Jin P, Chamberlin HM, Morgan DO, (1995) Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. Cell 83: 47-57.
-
(1995)
Cell
, vol.83
, pp. 47-57
-
-
Fisher, R.P.1
Jin, P.2
Chamberlin, H.M.3
Morgan, D.O.4
-
44
-
-
0033022375
-
The cdk-activating kinase (CAK): from yeast to mammals
-
Kaldis P, (1999) The cdk-activating kinase (CAK): from yeast to mammals. Cell Mol Life Sci 55: 284-296.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 284-296
-
-
Kaldis, P.1
-
45
-
-
0028089946
-
Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)
-
Tassan JP, Schultz SJ, Bartek J, Nigg EA, (1994) Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). J Cell Biol 127: 467-478.
-
(1994)
J Cell Biol
, vol.127
, pp. 467-478
-
-
Tassan, J.P.1
Schultz, S.J.2
Bartek, J.3
Nigg, E.A.4
-
46
-
-
0027943714
-
Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase
-
Matsuoka M, Kato JY, Fisher RP, Morgan DO, Sherr CJ, (1994) Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol Cell Biol 14: 7265-7275.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7265-7275
-
-
Matsuoka, M.1
Kato, J.Y.2
Fisher, R.P.3
Morgan, D.O.4
Sherr, C.J.5
-
47
-
-
33751522249
-
Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations of human thyrocytes by growth factors and TSH
-
Paternot S, Dumont JE, Roger PP, (2006) Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations of human thyrocytes by growth factors and TSH. Mol Endocrinol 20: 3279-3292.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3279-3292
-
-
Paternot, S.1
Dumont, J.E.2
Roger, P.P.3
-
48
-
-
0027973043
-
Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
-
Kato JY, Matsuoka M, Polyak K, Massague J, Sherr CJ, (1994) Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. Cell 79: 487-496.
-
(1994)
Cell
, vol.79
, pp. 487-496
-
-
Kato, J.Y.1
Matsuoka, M.2
Polyak, K.3
Massague, J.4
Sherr, C.J.5
-
49
-
-
30044438459
-
Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics
-
Larochelle S, Batliner J, Gamble MJ, Barboza NM, Kraybill BC, et al. (2006) Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nat Struct Mol Biol 13: 55-62.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 55-62
-
-
Larochelle, S.1
Batliner, J.2
Gamble, M.J.3
Barboza, N.M.4
Kraybill, B.C.5
-
50
-
-
29244468847
-
Secrets of a double agent: CDK7 in cell-cycle control and transcription
-
Fisher RP, (2005) Secrets of a double agent: CDK7 in cell-cycle control and transcription. J Cell Sci 118: 5171-5180.
-
(2005)
J Cell Sci
, vol.118
, pp. 5171-5180
-
-
Fisher, R.P.1
-
51
-
-
0034747803
-
Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop
-
Garrett S, Barton WA, Knights R, Jin P, Morgan DO, et al. (2001) Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop. Mol Cell Biol 21: 88-99.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 88-99
-
-
Garrett, S.1
Barton, W.A.2
Knights, R.3
Jin, P.4
Morgan, D.O.5
-
52
-
-
34248583324
-
Recognition of Cdk2 by Cdk7
-
Lolli G, Johnson LN, (2007) Recognition of Cdk2 by Cdk7. Proteins 67: 1048-1059.
-
(2007)
Proteins
, vol.67
, pp. 1048-1059
-
-
Lolli, G.1
Johnson, L.N.2
-
53
-
-
33947424005
-
Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells
-
Larochelle S, Merrick KA, Terret ME, Wohlbold L, Barboza NM, et al. (2007) Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol Cell 25: 839-850.
-
(2007)
Mol Cell
, vol.25
, pp. 839-850
-
-
Larochelle, S.1
Merrick, K.A.2
Terret, M.E.3
Wohlbold, L.4
Barboza, N.M.5
-
54
-
-
26444470797
-
Control of cell division and transcription by cyclin-dependent kinase-activating kinases in plants
-
Umeda M, Shimotohno A, Yamaguchi M, (2005) Control of cell division and transcription by cyclin-dependent kinase-activating kinases in plants. Plant Cell Physiol 46: 1437-1442.
-
(2005)
Plant Cell Physiol
, vol.46
, pp. 1437-1442
-
-
Umeda, M.1
Shimotohno, A.2
Yamaguchi, M.3
-
55
-
-
0033919678
-
Analysis of CAK activities from human cells
-
Kaldis P, Solomon MJ, (2000) Analysis of CAK activities from human cells. Eur J Biochem 267: 4213-4221.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4213-4221
-
-
Kaldis, P.1
Solomon, M.J.2
-
56
-
-
0032004973
-
The role of Cdk7 in CAK function, a retro-retrospective
-
Harper JW, Elledge SJ, (1998) The role of Cdk7 in CAK function, a retro-retrospective. Genes Dev 12: 285-289.
-
(1998)
Genes Dev
, vol.12
, pp. 285-289
-
-
Harper, J.W.1
Elledge, S.J.2
-
57
-
-
84864390302
-
Why minimal is not optimal: Driving the mammalian cell cycle-and drug discovery-with a physiologic CDK control network
-
Merrick KA, Fisher RP, (2012) Why minimal is not optimal: Driving the mammalian cell cycle-and drug discovery-with a physiologic CDK control network. Cell Cycle 11: 2600-2605.
-
(2012)
Cell Cycle
, vol.11
, pp. 2600-2605
-
-
Merrick, K.A.1
Fisher, R.P.2
-
58
-
-
0033559264
-
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
-
Cheng M, Olivier P, Diehl JA, Fero M, Roussel MF, et al. (1999) The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J 18: 1571-1583.
-
(1999)
EMBO J
, vol.18
, pp. 1571-1583
-
-
Cheng, M.1
Olivier, P.2
Diehl, J.A.3
Fero, M.4
Roussel, M.F.5
-
59
-
-
0141529760
-
P27Kip1 and p21Cip1 are not required for the formation of active D cyclin-cdk4 complexes
-
Bagui TK, Mohapatra S, Haura E, Pledger WJ, (2003) P27Kip1 and p21Cip1 are not required for the formation of active D cyclin-cdk4 complexes. Mol Cell Biol 23: 7285-7290.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7285-7290
-
-
Bagui, T.K.1
Mohapatra, S.2
Haura, E.3
Pledger, W.J.4
-
60
-
-
0037153424
-
Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1)
-
Sugimoto M, Martin N, Wilks DP, Tamai K, Huot TJ, et al. (2002) Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1). Oncogene 21: 8067-8074.
-
(2002)
Oncogene
, vol.21
, pp. 8067-8074
-
-
Sugimoto, M.1
Martin, N.2
Wilks, D.P.3
Tamai, K.4
Huot, T.J.5
-
61
-
-
23844462834
-
Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif
-
Zhu H, Nie L, Maki CG, (2005) Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif. J Biol Chem 280: 29282-29288.
-
(2005)
J Biol Chem
, vol.280
, pp. 29282-29288
-
-
Zhu, H.1
Nie, L.2
Maki, C.G.3
-
62
-
-
0038152755
-
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase
-
Bornstein G, Bloom J, Sitry-Shevah D, Nakayama K, Pagano M, et al. (2003) Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. J Biol Chem 278: 25752-25757.
-
(2003)
J Biol Chem
, vol.278
, pp. 25752-25757
-
-
Bornstein, G.1
Bloom, J.2
Sitry-Shevah, D.3
Nakayama, K.4
Pagano, M.5
-
63
-
-
1642378661
-
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
-
Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M, (2004) Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature 428: 190-193.
-
(2004)
Nature
, vol.428
, pp. 190-193
-
-
Bashir, T.1
Dorrello, N.V.2
Amador, V.3
Guardavaccaro, D.4
Pagano, M.5
-
64
-
-
0029784513
-
Cyclin-binding motifs are essential for the function of p21CIP1
-
Chen J, Saha P, Kornbluth S, Dynlacht BD, Dutta A, (1996) Cyclin-binding motifs are essential for the function of p21CIP1. Mol Cell Biol 16: 4673-4682.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4673-4682
-
-
Chen, J.1
Saha, P.2
Kornbluth, S.3
Dynlacht, B.D.4
Dutta, A.5
-
65
-
-
0037155824
-
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
-
Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeler S, (2002) Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. J Biol Chem 277: 9684-9689.
-
(2002)
J Biol Chem
, vol.277
, pp. 9684-9689
-
-
Rossig, L.1
Badorff, C.2
Holzmann, Y.3
Zeiher, A.M.4
Dimmeler, S.5
-
66
-
-
24744437350
-
Roscovitine targets, protein kinases and pyridoxal kinase
-
Bach S, Knockaert M, Reinhardt J, Lozach O, Schmitt S, et al. (2005) Roscovitine targets, protein kinases and pyridoxal kinase. J Biol Chem 280: 31208-31219.
-
(2005)
J Biol Chem
, vol.280
, pp. 31208-31219
-
-
Bach, S.1
Knockaert, M.2
Reinhardt, J.3
Lozach, O.4
Schmitt, S.5
-
67
-
-
74049087952
-
Impact of roscovitine, a selective CDK inhibitor, on cancer cells: bi-functionality increases its therapeutic potential
-
Wesierska-Gadek J, Borza A, Komina O, Maurer M, (2009) Impact of roscovitine, a selective CDK inhibitor, on cancer cells: bi-functionality increases its therapeutic potential. Acta Biochim Pol 56: 495-501.
-
(2009)
Acta Biochim Pol
, vol.56
, pp. 495-501
-
-
Wesierska-Gadek, J.1
Borza, A.2
Komina, O.3
Maurer, M.4
-
68
-
-
53249149292
-
CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases
-
Bettayeb K, Oumata N, Echalier A, Ferandin Y, Endicott JA, et al. (2008) CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene 27: 5797-5807.
-
(2008)
Oncogene
, vol.27
, pp. 5797-5807
-
-
Bettayeb, K.1
Oumata, N.2
Echalier, A.3
Ferandin, Y.4
Endicott, J.A.5
-
69
-
-
0038157142
-
Xpd/Ercc2 regulates CAK activity and mitotic progression
-
Chen J, Larochelle S, Li X, Suter B, (2003) Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424: 228-232.
-
(2003)
Nature
, vol.424
, pp. 228-232
-
-
Chen, J.1
Larochelle, S.2
Li, X.3
Suter, B.4
-
70
-
-
20244365948
-
Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6
-
Toogood PL, Harvey PJ, Repine JT, Sheehan DJ, VanderWel SN, et al. (2005) Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6. J Med Chem 48: 2388-2406.
-
(2005)
J Med Chem
, vol.48
, pp. 2388-2406
-
-
Toogood, P.L.1
Harvey, P.J.2
Repine, J.T.3
Sheehan, D.J.4
VanderWel, S.N.5
-
71
-
-
79952959945
-
Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21
-
Wang Y, Fisher JC, Mathew R, Ou L, Otieno S, et al. (2011) Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21. Nat Chem Biol 7: 214-221.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 214-221
-
-
Wang, Y.1
Fisher, J.C.2
Mathew, R.3
Ou, L.4
Otieno, S.5
-
72
-
-
84876860706
-
A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression
-
Merzel Schachter M, Merrick KA, Larochelle S, Hirschi A, Zhang C, et al. (2013) A Cdk7-Cdk4 T-Loop Phosphorylation Cascade Promotes G1 Progression. Mol Cell 50: 250-260.
-
(2013)
Mol Cell
, vol.50
, pp. 250-260
-
-
Merzel Schachter, M.1
Merrick, K.A.2
Larochelle, S.3
Hirschi, A.4
Zhang, C.5
-
73
-
-
56849109923
-
Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells
-
Merrick KA, Larochelle S, Zhang C, Allen JJ, Shokat KM, et al. (2008) Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells. Mol Cell 32: 662-672.
-
(2008)
Mol Cell
, vol.32
, pp. 662-672
-
-
Merrick, K.A.1
Larochelle, S.2
Zhang, C.3
Allen, J.J.4
Shokat, K.M.5
-
74
-
-
84861871242
-
Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion
-
Ganuza M, Saiz-Ladera C, Canamero M, Gomez G, Schneider R, et al. (2012) Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. EMBO J 31: 2498-2510.
-
(2012)
EMBO J
, vol.31
, pp. 2498-2510
-
-
Ganuza, M.1
Saiz-Ladera, C.2
Canamero, M.3
Gomez, G.4
Schneider, R.5
-
75
-
-
63149111417
-
The structure of CDK4/cyclin D3 has implications for models of CDK activation
-
Takaki T, Echalier A, Brown NR, Hunt T, Endicott JA, et al. (2009) The structure of CDK4/cyclin D3 has implications for models of CDK activation. Proc Natl Acad Sci U S A 106: 4171-4176.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4171-4176
-
-
Takaki, T.1
Echalier, A.2
Brown, N.R.3
Hunt, T.4
Endicott, J.A.5
-
76
-
-
0028099631
-
Cloning, expression and subcellular localization of the human homolog of p40MO15 catalytic subunit of cdk-activating kinase
-
Darbon JM, Devault A, Taviaux S, Fesquet D, Martinez AM, et al. (1994) Cloning, expression and subcellular localization of the human homolog of p40MO15 catalytic subunit of cdk-activating kinase. Oncogene 9: 3127-3138.
-
(1994)
Oncogene
, vol.9
, pp. 3127-3138
-
-
Darbon, J.M.1
Devault, A.2
Taviaux, S.3
Fesquet, D.4
Martinez, A.M.5
-
77
-
-
0030714114
-
Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes
-
Muller D, Bouchard C, Rudolph B, Steiner P, Stuckmann I, et al. (1997) Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes. Oncogene 15: 2561-2576.
-
(1997)
Oncogene
, vol.15
, pp. 2561-2576
-
-
Muller, D.1
Bouchard, C.2
Rudolph, B.3
Steiner, P.4
Stuckmann, I.5
-
78
-
-
0041836324
-
Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation
-
Kamura T, Hara T, Kotoshiba S, Yada M, Ishida N, et al. (2003) Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation. Proc Natl Acad Sci U S A 100: 10231-10236.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10231-10236
-
-
Kamura, T.1
Hara, T.2
Kotoshiba, S.3
Yada, M.4
Ishida, N.5
-
79
-
-
33644747700
-
Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest
-
Jarviluoma A, Child ES, Sarek G, Sirimongkolkasem P, Peters G, et al. (2006) Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest. Mol Cell Biol 26: 2430-2440.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2430-2440
-
-
Jarviluoma, A.1
Child, E.S.2
Sarek, G.3
Sirimongkolkasem, P.4
Peters, G.5
-
80
-
-
0028169236
-
p21-containing cyclin kinases exist in both active and inactive states
-
Zhang H, Hannon GJ, Beach D, (1994) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 8: 1750-1758.
-
(1994)
Genes Dev
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
Hannon, G.J.2
Beach, D.3
-
81
-
-
0029928180
-
Analysis of wild-type and mutant p21WAF-1 gene activities
-
Lin J, Reichner C, Wu X, Levine AJ, (1996) Analysis of wild-type and mutant p21WAF-1 gene activities. Mol Cell Biol 16: 1786-1793.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1786-1793
-
-
Lin, J.1
Reichner, C.2
Wu, X.3
Levine, A.J.4
-
82
-
-
34247577963
-
Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo
-
Zhan J, Easton JB, Huang S, Mishra A, Xiao L, et al. (2007) Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo. Mol Cell Biol 27: 3530-3541.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3530-3541
-
-
Zhan, J.1
Easton, J.B.2
Huang, S.3
Mishra, A.4
Xiao, L.5
-
83
-
-
0033532558
-
Mathematical analysis of binary activation of a cell cycle kinase which down-regulates its own inhibitor
-
Thron CD, (1999) Mathematical analysis of binary activation of a cell cycle kinase which down-regulates its own inhibitor. Biophys Chem 79: 95-106.
-
(1999)
Biophys Chem
, vol.79
, pp. 95-106
-
-
Thron, C.D.1
-
84
-
-
0030767422
-
Bistable biochemical switching and the control of the events of the cell cycle
-
Thron CD, (1997) Bistable biochemical switching and the control of the events of the cell cycle. Oncogene 15: 317-325.
-
(1997)
Oncogene
, vol.15
, pp. 317-325
-
-
Thron, C.D.1
-
85
-
-
32244445684
-
Distinct Specificities of pRb Phosphorylation by CDK4 Activated by Cyclin D1 or Cyclin D3: Differential Involvement in the Distinct Mitogenic Modes of Thyroid Epithelial Cells
-
Paternot S, Arsenijevic T, Coulonval K, Bockstaele L, Dumont JE, et al. (2006) Distinct Specificities of pRb Phosphorylation by CDK4 Activated by Cyclin D1 or Cyclin D3: Differential Involvement in the Distinct Mitogenic Modes of Thyroid Epithelial Cells. Cell Cycle 5: 61-70.
-
(2006)
Cell Cycle
, vol.5
, pp. 61-70
-
-
Paternot, S.1
Arsenijevic, T.2
Coulonval, K.3
Bockstaele, L.4
Dumont, J.E.5
-
86
-
-
67649205804
-
Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1
-
Hwang CY, Lee C, Kwon KS, (2009) Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1. Mol Cell Biol 29: 3379-3389.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3379-3389
-
-
Hwang, C.Y.1
Lee, C.2
Kwon, K.S.3
-
87
-
-
76749104377
-
Targeting the RB-pathway in cancer therapy
-
Knudsen ES, Wang JY, (2010) Targeting the RB-pathway in cancer therapy. Clin Cancer Res 16: 1094-1099.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1094-1099
-
-
Knudsen, E.S.1
Wang, J.Y.2
-
88
-
-
84870289371
-
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
-
Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, et al. (2012) Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med 18: 1503-1510.
-
(2012)
Nat Med
, vol.18
, pp. 1503-1510
-
-
Kwong, L.N.1
Costello, J.C.2
Liu, H.3
Jiang, S.4
Helms, T.L.5
-
89
-
-
0242365407
-
The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis
-
Coulonval K, Bockstaele L, Paternot S, Dumont JE, Roger PP, (2003) The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis. Exp Cell Res 291: 135-149.
-
(2003)
Exp Cell Res
, vol.291
, pp. 135-149
-
-
Coulonval, K.1
Bockstaele, L.2
Paternot, S.3
Dumont, J.E.4
Roger, P.P.5
-
90
-
-
0029957947
-
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation
-
Clurman BE, Sheaff RJ, Thress K, Groudine M, Roberts JM, (1996) Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes Dev 10: 1979-1990.
-
(1996)
Genes Dev
, vol.10
, pp. 1979-1990
-
-
Clurman, B.E.1
Sheaff, R.J.2
Thress, K.3
Groudine, M.4
Roberts, J.M.5
-
91
-
-
0035848706
-
Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence
-
Lin J, Jinno S, Okayama H, (2001) Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. Oncogene 20: 2000-2009.
-
(2001)
Oncogene
, vol.20
, pp. 2000-2009
-
-
Lin, J.1
Jinno, S.2
Okayama, H.3
-
92
-
-
0035898652
-
T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity
-
Larochelle S, Chen J, Knights R, Pandur J, Morcillo P, et al. (2001) T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity. EMBO J 20: 3749-3759.
-
(2001)
EMBO J
, vol.20
, pp. 3749-3759
-
-
Larochelle, S.1
Chen, J.2
Knights, R.3
Pandur, J.4
Morcillo, P.5
-
93
-
-
70350442978
-
TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II
-
Glover-Cutter K, Larochelle S, Erickson B, Zhang C, Shokat K, et al. (2009) TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II. Mol Cell Biol 29: 5455-5464.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5455-5464
-
-
Glover-Cutter, K.1
Larochelle, S.2
Erickson, B.3
Zhang, C.4
Shokat, K.5
-
94
-
-
79952837100
-
CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells
-
Bettayeb K, Baunbaek D, Delehouze C, Loaec N, Hole AJ, et al. (2010) CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells. Genes Cancer 1: 369-380.
-
(2010)
Genes Cancer
, vol.1
, pp. 369-380
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Bettayeb, K.1
Baunbaek, D.2
Delehouze, C.3
Loaec, N.4
Hole, A.J.5
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