-
2
-
-
1642323740
-
Protein kinase inhibitors: Insights into drug design from structure
-
Noble ME, Endicott JA, Johnson LN. Protein kinase inhibitors: insights into drug design from structure. Science 2004;303:1800-1805.
-
(2004)
Science
, vol.303
, pp. 1800-1805
-
-
Noble, M.E.1
Endicott, J.A.2
Johnson, L.N.3
-
3
-
-
33645802169
-
Cyclin-dependent kinase pathways as targets for cancer treatment
-
Shapiro GI. Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol 2006;24:1770-1783.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1770-1783
-
-
Shapiro, G.I.1
-
4
-
-
0027185999
-
CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15
-
Solomon MJ, Harper JW, Shuttleworth J. CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15: EMBO J 1993;12:3133-3142.
-
(1993)
EMBO J
, vol.12
, pp. 3133-3142
-
-
Solomon, M.J.1
Harper, J.W.2
Shuttleworth, J.3
-
5
-
-
0027007963
-
Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase
-
Solomon MJ, Lee T, Kirschner MW. Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol Biol Cell 1992;3:13-27.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 13-27
-
-
Solomon, M.J.1
Lee, T.2
Kirschner, M.W.3
-
6
-
-
0027296041
-
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues
-
Fesquet D, Labbe' J-C, Derancourt J, Capony J-P, Galas S, Girard F, Lorca T, Shuttleworth J, Doree M, Cavadore JC. The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues. EMBO J 1993;12:3111-3121.
-
(1993)
EMBO J
, vol.12
, pp. 3111-3121
-
-
Fesquet, D.1
Labbe', J.-C.2
Derancourt, J.3
Capony, J.-P.4
Galas, S.5
Girard, F.6
Lorca, T.7
Shuttleworth, J.8
Doree, M.9
Cavadore, J.C.10
-
7
-
-
0027251024
-
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2
-
Poon RYC, Yamashita K, Adamczewski JP, Hunt T, Shuttleworth J. The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2. EMBO J 1993;12:3123-3132.
-
(1993)
EMBO J
, vol.12
, pp. 3123-3132
-
-
Poon, R.Y.C.1
Yamashita, K.2
Adamczewski, J.P.3
Hunt, T.4
Shuttleworth, J.5
-
8
-
-
0027994603
-
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase
-
Fisher RP, Morgan DO. A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase. Cell 1994;78:713-724.
-
(1994)
Cell
, vol.78
, pp. 713-724
-
-
Fisher, R.P.1
Morgan, D.O.2
-
9
-
-
0028270189
-
Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
-
Kato J-Y, Matsuoka M, Storm DK, Sherr CJ. Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol Cell Biol 1994;14:2713-2721.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2713-2721
-
-
Kato, J.-Y.1
Matsuoka, M.2
Storm, D.K.3
Sherr, C.J.4
-
10
-
-
0027943714
-
Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase
-
Matsuoka M, Kato J-Y, Fisher RP, Morgan DO, Sherr CJ. Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol Cell Biol 1994;14:7265-7275.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7265-7275
-
-
Matsuoka, M.1
Kato, J.-Y.2
Fisher, R.P.3
Morgan, D.O.4
Sherr, C.J.5
-
11
-
-
0028856425
-
MAT1, a new RING-finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK
-
Devault A, Martinez AM, Fesquet D, Labbe' JC, Tassan JP, Nigg EA, Cavadore JC, Doree M. MAT1, a new RING-finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. EMBO J 1995;14:5027-5036.
-
(1995)
EMBO J
, vol.14
, pp. 5027-5036
-
-
Devault, A.1
Martinez, A.M.2
Fesquet, D.3
Labbe', J.C.4
Tassan, J.P.5
Nigg, E.A.6
Cavadore, J.C.7
Doree, M.8
-
12
-
-
0028807103
-
Alternative mechanism of CAK assembly require an assembly factor or an activating kinase
-
Fisher RP, Jin P, Chamberlin HM, Morgan DO. Alternative mechanism of CAK assembly require an assembly factor or an activating kinase. Cell 1995;83:47-57.
-
(1995)
Cell
, vol.83
, pp. 47-57
-
-
Fisher, R.P.1
Jin, P.2
Chamberlin, H.M.3
Morgan, D.O.4
-
13
-
-
0031016629
-
Dual phosphorylation of the T-loop in cdk7: Its role in controlling cyclin H binding and CAK activity
-
Martinez A-M, Afshar M, Martin F, Cavadore J-C, Labbé J-C, Doree M. Dual phosphorylation of the T-loop in cdk7: its role in controlling cyclin H binding and CAK activity. EMBO J 1997;16:343-354.
-
(1997)
EMBO J
, vol.16
, pp. 343-354
-
-
Martinez, A.-M.1
Afshar, M.2
Martin, F.3
Cavadore, J.-C.4
Labbé, J.-C.5
Doree, M.6
-
14
-
-
0034747803
-
Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop
-
Garrett S, Barton WA, Knights R, Jin P, Morgan DO, Fisher RP. Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop. Mol Cell Biol 2001;21:88-99.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 88-99
-
-
Garrett, S.1
Barton, W.A.2
Knights, R.3
Jin, P.4
Morgan, D.O.5
Fisher, R.P.6
-
15
-
-
0028540405
-
Use of an oriented peptide library to determine the optimal substrates of protein kinases
-
Songyang Z, Blechner S, Hoagland N, Hoekstra MF, Piwnica-Worms H, Cantley LC. Use of an oriented peptide library to determine the optimal substrates of protein kinases. Curr Biol 1994;4:973-982.
-
(1994)
Curr Biol
, vol.4
, pp. 973-982
-
-
Songyang, Z.1
Blechner, S.2
Hoagland, N.3
Hoekstra, M.F.4
Piwnica-Worms, H.5
Cantley, L.C.6
-
16
-
-
0033224309
-
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
-
Brown NR, Noble ME, Endicott JA, Johnson LN. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat Cell Biol 1999;1:438-443.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 438-443
-
-
Brown, N.R.1
Noble, M.E.2
Endicott, J.A.3
Johnson, L.N.4
-
17
-
-
0028983384
-
p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F
-
Zhu L, Harlow E, Dynlacht BD. p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev 1995;9:1740-1752.
-
(1995)
Genes Dev
, vol.9
, pp. 1740-1752
-
-
Zhu, L.1
Harlow, E.2
Dynlacht, B.D.3
-
18
-
-
0029928180
-
Analysis of wild-type and mutant p21WAF-1 gene activities
-
Lin J, Reichner C, Wu X, Levine AJ. Analysis of wild-type and mutant p21WAF-1 gene activities. Mol Cell Biol 1996;16:1786-1793.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1786-1793
-
-
Lin, J.1
Reichner, C.2
Wu, X.3
Levine, A.J.4
-
19
-
-
0030990095
-
Specific regulation of E2F family members by cyclin-dependent kinases
-
Dynlacht BD, Moberg K, Lees JA, Harlow E, Zhu L. Specific regulation of E2F family members by cyclin-dependent kinases. Mol Cell Biol 1997;17:3867-3875.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3867-3875
-
-
Dynlacht, B.D.1
Moberg, K.2
Lees, J.A.3
Harlow, E.4
Zhu, L.5
-
20
-
-
0347520938
-
Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A
-
Lowe ED, Tews I, Cheng KY, Brown NR, Gul S, Noble ME, Gamblin SJ, Johnson LN. Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. Biochemistry 2002;41:15625-15634.
-
(2002)
Biochemistry
, vol.41
, pp. 15625-15634
-
-
Lowe, E.D.1
Tews, I.2
Cheng, K.Y.3
Brown, N.R.4
Gul, S.5
Noble, M.E.6
Gamblin, S.J.7
Johnson, L.N.8
-
21
-
-
0032929012
-
Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes
-
Adams PD, Li X, Sellers WR, Baker KB, Leng X, Harper JW, Taya Y, Kaelin WG Jr. Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes. Mol Cell Biol 1999;19:1068-1080.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1068-1080
-
-
Adams, P.D.1
Li, X.2
Sellers, W.R.3
Baker, K.B.4
Leng, X.5
Harper, J.W.6
Taya, Y.7
Kaelin Jr., W.G.8
-
22
-
-
0034647433
-
The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A
-
Luciani MG, Hutchins JR, Zheleva D, Hupp TR. The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A. J Mol Biol 2000;300:503-518.
-
(2000)
J Mol Biol
, vol.300
, pp. 503-518
-
-
Luciani, M.G.1
Hutchins, J.R.2
Zheleva, D.3
Hupp, T.R.4
-
24
-
-
0029973557
-
Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
-
Adams PD, Sellers WR, Sharma SK, Wu AD, Nalin CM, Kaelin WG Jr. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol Cell Biol 1996;16:6623-6633.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6623-6633
-
-
Adams, P.D.1
Sellers, W.R.2
Sharma, S.K.3
Wu, A.D.4
Nalin, C.M.5
Kaelin Jr., W.G.6
-
25
-
-
0029784513
-
Cyclin-binding motifs are essential for the function of p21CIP1
-
Chen J, Saha P, Kornbluth S, Dynlacht BD, Dutta A. Cyclin-binding motifs are essential for the function of p21CIP1. Mol Cell Biol 1996;16:4673-4682.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4673-4682
-
-
Chen, J.1
Saha, P.2
Kornbluth, S.3
Dynlacht, B.D.4
Dutta, A.5
-
26
-
-
33747359918
-
The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition
-
Cheng KY, Noble ME, Skamnaki V, Brown NR, Lowe ED, Kontogiannis L, Shen K, Cole PA, Siligardi G, Johnson LN. The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition. J Biol Chem 2006;281:23167-23179.
-
(2006)
J Biol Chem
, vol.281
, pp. 23167-23179
-
-
Cheng, K.Y.1
Noble, M.E.2
Skamnaki, V.3
Brown, N.R.4
Lowe, E.D.5
Kontogiannis, L.6
Shen, K.7
Cole, P.A.8
Siligardi, G.9
Johnson, L.N.10
-
27
-
-
0032167631
-
Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A
-
Schulman BA, Lindstrom DL, Harlow E. Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A. Proc Natl Acad Sci USA 1998;95:10453-10458.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10453-10458
-
-
Schulman, B.A.1
Lindstrom, D.L.2
Harlow, E.3
-
28
-
-
7944231428
-
The crystal structure of human CDK7 and its protein recognition properties
-
Lolli G, Lowe ED, Brown NR, Johnson LN. The crystal structure of human CDK7 and its protein recognition properties. Structure 2004;12:2067-2079.
-
(2004)
Structure
, vol.12
, pp. 2067-2079
-
-
Lolli, G.1
Lowe, E.D.2
Brown, N.R.3
Johnson, L.N.4
-
29
-
-
0034725689
-
Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcrition activities
-
Busso D, Keriel A, Sandrock B, Poterszman A, Gileadi O, Egly J-M. Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcrition activities. J Biol Chem 2000;275:22815-22823.
-
(2000)
J Biol Chem
, vol.275
, pp. 22815-22823
-
-
Busso, D.1
Keriel, A.2
Sandrock, B.3
Poterszman, A.4
Gileadi, O.5
Egly, J.-M.6
-
30
-
-
0032400516
-
Modelling repressor proteins docking to DNA
-
Aloy P, Moont G, Gabb HA, Querol E, Aviles FX, Sternberg MJ. Modelling repressor proteins docking to DNA. Proteins 1998;33:535-549.
-
(1998)
Proteins
, vol.33
, pp. 535-549
-
-
Aloy, P.1
Moont, G.2
Gabb, H.A.3
Querol, E.4
Aviles, F.X.5
Sternberg, M.J.6
-
31
-
-
0033562633
-
Use of pair potentials across protein interfaces in screening predicted docked complexes
-
Moont G, Gabb HA, Sternberg MJ. Use of pair potentials across protein interfaces in screening predicted docked complexes. Proteins 1999;35:364-373.
-
(1999)
Proteins
, vol.35
, pp. 364-373
-
-
Moont, G.1
Gabb, H.A.2
Sternberg, M.J.3
-
32
-
-
0031565730
-
Modelling protein docking using shape complementarity, electrostatics and biochemical information
-
Gabb HA, Jackson RM, Sternberg MJ. Modelling protein docking using shape complementarity, electrostatics and biochemical information. J Mol Biol 1997;272:106-120.
-
(1997)
J Mol Biol
, vol.272
, pp. 106-120
-
-
Gabb, H.A.1
Jackson, R.M.2
Sternberg, M.J.3
-
33
-
-
0035789518
-
GROMACS 3.0: A package for molecular simulation and trajectory analysis
-
Lindahl E, Hess B, van der Spoel D. GROMACS 3.0: a package for molecular simulation and trajectory analysis. J Mol Mod 2001;7:306-317.
-
(2001)
J Mol Mod
, vol.7
, pp. 306-317
-
-
Lindahl, E.1
Hess, B.2
van der Spoel, D.3
-
34
-
-
0028103275
-
The CCP4 (collaborative computational project number 4) suite: Programmes for protein crystallography. Acta Cryst D Biol Crystallogr
-
4
-
CCP4. The CCP4 (collaborative computational project number 4) suite: programmes for protein crystallography. Acta Cryst D Biol Crystallogr 1994;50:760-763.
-
(1994)
, vol.50
, pp. 760-763
-
-
CCP1
-
35
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey PD, Russo AA, Polyak K, Gibbs E, Hurwitz J, Massague J, Pavletich NP. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 1995;376:313-320.
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
Russo, A.A.2
Polyak, K.3
Gibbs, E.4
Hurwitz, J.5
Massague, J.6
Pavletich, N.P.7
-
36
-
-
0035265679
-
Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2
-
Song H, Hanlon N, Brown NR, Noble ME, Johnson LN, Barford D. Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol Cell 2001;7:615-626.
-
(2001)
Mol Cell
, vol.7
, pp. 615-626
-
-
Song, H.1
Hanlon, N.2
Brown, N.R.3
Noble, M.E.4
Johnson, L.N.5
Barford, D.6
-
37
-
-
33646195686
-
Detection of protein assemblies in crystals
-
Berthold MR, Glen R, Diederichs K, Kohlbacher O, Fischer I, editors, Berlin, Heidelberg: Springer-Verlag;
-
Krissinel E, Henrick K. Detection of protein assemblies in crystals. In: Berthold MR, Glen R, Diederichs K, Kohlbacher O, Fischer I., editors. Lecture Notes in Computer Science, CompLife, Vol.3695. Berlin, Heidelberg: Springer-Verlag; 2005. pp 163-174.
-
(2005)
Lecture Notes in Computer Science, CompLife
, vol.3695
, pp. 163-174
-
-
Krissinel, E.1
Henrick, K.2
-
38
-
-
0030598848
-
Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
-
Mohammadi M, Schlessinger J, Hubbard SR. Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism. Cell 1996;86:577-587.
-
(1996)
Cell
, vol.86
, pp. 577-587
-
-
Mohammadi, M.1
Schlessinger, J.2
Hubbard, S.R.3
-
39
-
-
0035045092
-
Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation
-
Lindauer K, Loerting T, Liedl KR, Kroemer RT. Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation. Protein Eng 2001;14:27-37.
-
(2001)
Protein Eng
, vol.14
, pp. 27-37
-
-
Lindauer, K.1
Loerting, T.2
Liedl, K.R.3
Kroemer, R.T.4
-
40
-
-
16644397843
-
Developments in the CCP4 molecular-graphics project
-
Potterton L, McNicholas S, Krissinel E, Gruber J, Cowtan K, Emsley P, Murshudov GN, Cohen S, Perrakis A, Noble M. Developments in the CCP4 molecular-graphics project. Acta Crystallogr D Biol Crystallogr 2004;60:2288-2294.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 2288-2294
-
-
Potterton, L.1
McNicholas, S.2
Krissinel, E.3
Gruber, J.4
Cowtan, K.5
Emsley, P.6
Murshudov, G.N.7
Cohen, S.8
Perrakis, A.9
Noble, M.10
-
41
-
-
0031547966
-
Electrostatic complementarity at protein/protein interfaces
-
McCoy AJ, Chandana Epa V, Colman PM. Electrostatic complementarity at protein/protein interfaces. J Mol Biol 1997;268:570-584.
-
(1997)
J Mol Biol
, vol.268
, pp. 570-584
-
-
McCoy, A.J.1
Chandana Epa, V.2
Colman, P.M.3
-
42
-
-
14844307019
-
The structure of cyclin E1/CDK2: Implications for CDK2 activation and CDK2-independent roles
-
Honda R, Lowe ED, Dubinina E, Skamnaki V, Cook A, Brown NR, Johnson LN. The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles. EMBO J 2005;24:452-463.
-
(2005)
EMBO J
, vol.24
, pp. 452-463
-
-
Honda, R.1
Lowe, E.D.2
Dubinina, E.3
Skamnaki, V.4
Cook, A.5
Brown, N.R.6
Johnson, L.N.7
-
43
-
-
0034630762
-
The N-terminal domains of cyclin-dependent kinase inhibitory proteins block the phosphorylation of cdk2/Cyclin E by the CDK-activating kinase
-
Rank KB, Evans DB, Sharma SK. The N-terminal domains of cyclin-dependent kinase inhibitory proteins block the phosphorylation of cdk2/Cyclin E by the CDK-activating kinase. Biochem Biophys Res Commun 2000;271:469-473.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 469-473
-
-
Rank, K.B.1
Evans, D.B.2
Sharma, S.K.3
-
46
-
-
0242353366
-
Cdk7 functions as a cdk5 activating kinase in brain
-
Rosales J, Han B, Lee KY. Cdk7 functions as a cdk5 activating kinase in brain. Cell Physiol Biochem 2003;13:285-296.
-
(2003)
Cell Physiol Biochem
, vol.13
, pp. 285-296
-
-
Rosales, J.1
Han, B.2
Lee, K.Y.3
-
47
-
-
0034786018
-
Structure and regulation of the CDK5-p25(nck5a) complex
-
Tarricone C, Dhavan R, Peng J, Areces LB, Tsai LH, Musacchio A. Structure and regulation of the CDK5-p25(nck5a) complex. Mol Cell 2001;8:657-669.
-
(2001)
Mol Cell
, vol.8
, pp. 657-669
-
-
Tarricone, C.1
Dhavan, R.2
Peng, J.3
Areces, L.B.4
Tsai, L.H.5
Musacchio, A.6
-
48
-
-
0032541640
-
Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d
-
Brotherton DH, Dhanaraj V, Wick S, Brizuela L, Domaille PJ, Volyanik E, Xu X, Parisini E, Smith BO, Archer SJ, Serrano M, Brenner SL, Blundell TL, Laue ED. Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d. Nature 1998;395:244-250.
-
(1998)
Nature
, vol.395
, pp. 244-250
-
-
Brotherton, D.H.1
Dhanaraj, V.2
Wick, S.3
Brizuela, L.4
Domaille, P.J.5
Volyanik, E.6
Xu, X.7
Parisini, E.8
Smith, B.O.9
Archer, S.J.10
Serrano, M.11
Brenner, S.L.12
Blundell, T.L.13
Laue, E.D.14
-
49
-
-
0029147732
-
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
-
Aprelikova O, Xiong Y, Liu ET. Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J Biol Chem 1995;270:18195-18197.
-
(1995)
J Biol Chem
, vol.270
, pp. 18195-18197
-
-
Aprelikova, O.1
Xiong, Y.2
Liu, E.T.3
-
50
-
-
0029665852
-
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
-
Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 1996;382:325-331.
-
(1996)
Nature
, vol.382
, pp. 325-331
-
-
Russo, A.A.1
Jeffrey, P.D.2
Patten, A.K.3
Massague, J.4
Pavletich, N.P.5
|