Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics

Nature Structural and Molecular Biology

Volumn 13, Issue 1, 2006, Pages 55-62

  Larochelle, Stéphane ^a   Batliner, Jasmin ^a,b   Gamble, Matthew J ^a   Barboza, Nora M ^a   Kraybill, Brian C ^c   Blethrow, Justin D ^c   Shokat, Kevan M ^c   Fisher, Robert P ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE ACTIVATING KINASE; PEPTIDE; PROTEIN SPT5; RNA POLYMERASE II; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; CELL CYCLE REGULATION; CHEMICAL GENETICS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBUNIT; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; TRANSCRIPTION REGULATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CELL EXTRACTS; CELL NUCLEUS; CONSERVED SEQUENCE; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 30044438459     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb1028     Document Type: Article

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