Expression of Concern: “p27Kip1 Inhibits Cyclin D–Cyclin-Dependent Kinase 4 by Two Independent Modes” (Mol Cell Biol, 29, 4, (986-999), 10.1128/MCB.00898-08);P27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes

Molecular and Cellular Biology

Volumn 29, Issue 4, 2009, Pages 986-999

  Ray, Arpita ^a   James, Melissa K ^a   Larochelle, Stéphane ^b   Fisher, Robert P ^b   Blain, Stacy W ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; CYCLIN D; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE ACTIVATING KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; TYROSINE; CYCLIN DEPENDENT KINASE; CYCLIN H; CYCLIN-DEPENDENT KINASE-ACTIVATING KINASE; CYCLINE; MUTANT PROTEIN; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL CELL; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MINK; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; AMINO ACID SUBSTITUTION; ANIMAL; CATALYSIS; DRUG ANTAGONISM; METABOLISM; MOUSE; PHOSPHORYLATION;

SCHIZOSACCHAROMYCETACEAE;

AMINO ACID SUBSTITUTION; ANIMALS; CATALYSIS; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME ACTIVATION; G0 PHASE; MICE; MUTANT PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; TYROSINE;

EID: 59449106702     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/mcb.00324-22     Document Type: Erratum

References (39)

1. Adams, P. D., X. Li, W. R. Sellers, K. B. Baker, X. Leng, J. W. Harper, Y. Taya, and W. G. Kaelin, Jr. 1999. Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes. Mol. Cell. Biol. 19:1068-1080.
2. Adams, P. D., W. R. Sellers, S. K. Sharma, A. D. Wu, C. M. Nalin, and W. G. Kaelin, Jr. 1996. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol. Cell. Biol. 16:6623-6633.
3. Cip1 promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export. J. Biol. Chem. 277:8517-8523.
4. Aprelikova, O., Y. Xiong, and E. T. Liu. 1995. Both p16 and p21 families of cyclin-dependent kinase inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J. Biol. Chem. 270:18195-18197.
5. Bagui, T. K., S. Mohapatra, E. Haura, and W. J. Pledger. 2003. p27Kip1 and p21Cip1 are not required for the formation of active cyclin D-cdk4 complexes. Mol. Biol. Cell 23:7285-7290.
6. Blain, S. W. 2008. Switching cyclin D-cdk4 kinase activity on and off. Cell Cycle 7:892-898.
7. Blain, S. W., E. Montalvo, and J. Massague. 1997. Differential interaction of the cyclin-dependent kinase (cdk) inhibitor p27 with cyclin A-cdk2 and cyclin D2-cdk4. J. Biol. Chem. 272:25863-25872.
8. Bockstaele, L., K. Coulonval, H. Kooken, S. Paternot, and P. P. Roger. 2006. Regulation of CDK4. Cell Div. 1:25.
9. Bockstaele, L., H. Kooken, F. Libert, S. Paternot, J. E. Dumont, Y. de Launoit, P. P. Roger, and K. Coulonval. 2006. Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4 (CDK4): its relationship with cyclins and CDK "inhibitors". Mol. Cell. Biol. 26:5070-5085.
10. Buck, V., P. Russell, and J. B. A. Millar. 1995. Identification of a cdk activating kinase in fission yeast. EMBO J. 14:6173-6183.
11. Kip1 CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1571-1583.
12. Cheng, M., V. Sexl, C. J. Sherr, and M. Roussel. 1998. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc. Natl. Acad. Sci. USA 95:1091-1096.
13. Chu, I., J. Sun, A. Arnaout, H. Kahn, W. Hanna, S. Narod, P. Sun, C. K. Tan, L. Hengst, and J. M. Slingerland. 2007. p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2. Cell 128:281-294.
14. Chu, I. M., L. Hengst, and J. M. Slingerland. 2008. The cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat. Rev. Cancer 8:253-267.
15. Cismowski, M. J., G. M. Laff, M. J. Solomon, and S. I. Reed. 1995. KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Mol. Cell. Biol. 15:2983-2992.
16. Coulonval, K., L. Bockstaele, S. Paternot, J. E. Dumont, and P. P. Roger. 2003. The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its sub-units demonstrated by two-dimensional gel electrophoresis. Exp. Cell Res. 291:135-149.
17. Fisher, R. P. 2005. Secrets of a double agent: cdk7 in cell cycle control and transcription. J. Cell Sci. 118:5171-5180.
18. Fisher, R. P. 1997. Reconstitution of mammalian cdk activating kinase. Methods Enzymol. 283:256-270.
19. Gladden, A. B., and J. A. Diehl. 2005. Location, location, location: the role of cyclin D1 nuclear localization in cancer. J. Cell. Biochem. 96:906-913.
20. Grimmler, M., Y. Wang, T. Mund, Z. Cilensek, E. M. Keidel, M. B. Waddell, H. Jakel, M. Kullmann, R. W. Kriwacki, and L. Hengst. 2007. Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell 128:269-280.
21. Hermand, D., A. Pihlak, T. Westerling, V. Damagnez, J. Vandenhaute, G. Cottarel, and T. P. Makela. 1998. Fission yeast Csk1 is a CAK-activating kinase (CAKAK). EMBO J. 17:7230-7238.
22. Kip1 controls its cyclin D-cdk4 activity. Mol. Cell. Biol. 28:498-510.
23. Kato, J., M. Matsuoka, K. Polyak, J. Massagué, and C. J. Sherr. 1994. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase-4 activation. Cell 79:487-496.
24. Kato, J.-Y., M. Matsuoka, D. K Strom, and C. J. Sherr. 1994. Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase. Mol. Cell. Biol. 14:2713-2721.
25. LaBaer, J., M. D. Garrett, L. F. Stevenson, J. M. Slingerland, C. Sandhu, H. S. Chou, A. Fattaey, and E. Harlow. 1997. New functional activities for the p21 family of CDK inhibitors. Genes Dev. 11:847-862.
26. Larochelle, S., J. Batliner, M. J. Gamble, N. M. Barboza, B. C. Kraybill, J. D. Blethrow, K. M. Shokat, and R. P. Fisher. 2006. Dichotomous but stringent substrate selection by dual function cdk7 complex revealed by chemical genetics. Nat. Struct. Mol. Biol. 13:55-62.
27. Larochelle, S., K. A. Merrick, M. E. Terret, L. Wohlbold, N. M. Barboza, C. Zhang, K. M. Shokat, P. V. Jallepalli, and R. P. Fisher. 2007. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol. Cell 25:839-850.
28. Lee, K. M., J. E. Saiz, W. A. Barton, and R. P. Fisher. 1999. Cdc2 activation in fission yeast depends on Mcs6 and Csk1, two partially redundant cdk-activating kinases. Curr. Biol. 9:441-444.
29. Malumbres, M., and M. Barbacid. 2001. To cycle or not to cycle: a critical decision in cancer. Nat. Rev. Cancer 1:222-231.
30. Matsuoka, M., J.-Y. Kato, R. P. Fisher, D. O. Morgan, and C. J. Sherr. 1994. Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol. Cell. Biol. 14:7265-7275.
31. Paternot, S., K. Coulonval, J. E. Dumont, and P. P. Roger. 2003. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells. J. Biol. Chem. 278:26533-26540.
32. Pavletich, N. P. 1999. Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J. Mol. Biol. 287:821-828.
33. Kip1, a cyclin-cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8:9-22.
34. Russo, A. A., P. D. Jeffrey, and N. Pavletich. 1996. Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat. Struct. Biol. 3:696-700.
35. Saiz, J. E., and R. P. Fisher. 2002. A CDK-activating kinase network is required in cell cycle control and transcription in fission yeast. Curr. Biol. 12:1100-1105.
36. Sherr, C. J., and J. M. Roberts. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
37. Soos, T. J., H. Kiyokawa, J. S. Yan, M. S. Rubin, A. Giordano, A. DeBlasio, S. Bottega, B. Wong, J. Mendelsohn, and A. Koff. 1996. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ. 7:135-146.
38. Sugimoto, M., T. Nakamura, N. Ohtani, L. Hampson, I. N. Hampson, A. Shimamoto, Y. Furuichi, K. Okumura, S. Niwa, Y. Taya, and E. Hara. 1999. Regulation of CDK4 activity by a novel CDK4-binding protein, p34 (SEI-1). Genes Dev. 13:3027-3033.
39. Wallace, M., and K. L. Ball. 2004. Docking-dependent regulation of the Rb tumor suppressor protein by Cdk4. Mol. Cell. Biol. 12:5606-5619.