Mathematical analysis of binary activation of a cell cycle kinase which down-regulates its own inhibitor

Biophysical Chemistry

Volumn 79, Issue 2, 1999, Pages 95-106

  Thron, C D ^a  

^a NONE   (United States)

Author keywords

Biochemical switch; Bistability; Cyclin dependent kinase inhibitor; Saddle node bifurcation

Indexed keywords

CYCLIN E; PROTEIN P27;

ARTICLE; CELL CYCLE; ENZYME ACTIVATION; ENZYME ACTIVITY; FEEDBACK SYSTEM; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL;

ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME STABILITY; HUMANS; KINETICS; MATHEMATICS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 0033532558     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(99)00041-1     Document Type: Article

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