Structure and mechanism of rhomboid protease

Journal of Biological Chemistry

Volumn 288, Issue 22, 2013, Pages 15430-15436

  Ha, Ya ^a   Akiyama, Yoshinori ^b   Xue, Yi ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ASSAY; BIOLOGICAL FUNCTIONS; CATALYTIC MECHANISMS; CONFORMATIONAL CHANGE; CRYSTALLOGRAPHIC ANALYSIS; MEMBRANE PROTEINS; MEMBRANE-SPANNING SEGMENTS; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS; ESCHERICHIA COLI; SUBSTRATES;

BIOLOGICAL MEMBRANES;

3,4 DICHLOROISOCOUMARIN; CHYMOTRYPSIN; DIISOPROPYL FLUOROPHOSPHATASE; MEMBRANE PROTEIN; PROTEIN PRECURSOR; RHOMBOID PROTEASE; SERINE PROTEINASE; SPITZ PROTEIN; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR DELTA; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; DEACYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITOR COMPLEX; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME STRUCTURE; HYDROGEN BOND; HYDROPHILICITY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN MOTIF; REVIEW;

ENZYME MECHANISMS; MEMBRANE PROTEINS; PROTEIN STRUCTURE; RHOMBOID PROTEASE; SERINE PROTEASE;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; ENDOPEPTIDASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MEMBRANE PROTEINS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 84878404648     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R112.422378     Document Type: Review

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