-
1
-
-
33846275257
-
Structural basis for intramembrane proteolysis by rhomboid serine proteases
-
Ben-Shem A, Fass D, Bibi E (2007) Structural basis for intramembrane proteolysis by rhomboid serine proteases. Proc Natl Acad Sci USA 104: 462-466
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 462-466
-
-
Ben-Shem, A.1
Fass, D.2
Bibi, E.3
-
2
-
-
0025060344
-
rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster
-
Bier E, Jan LY, Jan YN (1990) rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev 4: 190-203
-
(1990)
Genes Dev
, vol.4
, pp. 190-203
-
-
Bier, E.1
Jan, L.Y.2
Jan, Y.N.3
-
4
-
-
0142115409
-
EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye
-
Brown KE, Freeman M (2003) EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130: 5401-5412
-
(2003)
Development
, vol.130
, pp. 5401-5412
-
-
Brown, K.E.1
Freeman, M.2
-
5
-
-
0030866482
-
In situ activation pattern of Drosophila EGF receptor pathway during development
-
Gabay L, Seger R, Shilo BZ (1997) In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277: 1103-1106
-
(1997)
Science
, vol.277
, pp. 1103-1106
-
-
Gabay, L.1
Seger, R.2
Shilo, B.Z.3
-
6
-
-
0036339998
-
Mechanism of activation of the Drosophila EGF receptor by the TGFalpha ligand Gurken during oogenesis
-
Ghiglione C, Bach EA, Paraiso Y, Carraway III KL, Noselli S, Perrimon N (2002) Mechanism of activation of the Drosophila EGF receptor by the TGFalpha ligand Gurken during oogenesis. Development 129: 175-186
-
(2002)
Development
, vol.129
, pp. 175-186
-
-
Ghiglione, C.1
Bach, E.A.2
Paraiso, Y.3
Carraway III, K.L.4
Noselli, S.5
Perrimon, N.6
-
7
-
-
33748432696
-
Soma-germline interactions coordinate homeostasis and growth in the Drosophila gonad
-
Gilboa L, Lehmann R (2006) Soma-germline interactions coordinate homeostasis and growth in the Drosophila gonad. Nature 443: 97-100
-
(2006)
Nature
, vol.443
, pp. 97-100
-
-
Gilboa, L.1
Lehmann, R.2
-
8
-
-
0029855245
-
The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
-
Golembo M, Raz E, Shilo BZ (1996) The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122: 3363-3370
-
(1996)
Development
, vol.122
, pp. 3363-3370
-
-
Golembo, M.1
Raz, E.2
Shilo, B.Z.3
-
9
-
-
0034667916
-
Brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling
-
Guichard A, Roark M, Ronshaugen M, Bier E (2000) Brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling. Dev Biol 226: 255-266
-
(2000)
Dev Biol
, vol.226
, pp. 255-266
-
-
Guichard, A.1
Roark, M.2
Ronshaugen, M.3
Bier, E.4
-
10
-
-
0025796847
-
Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough
-
Heberlein U, Rubin GM (1991) Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough. Dev Biol 144: 353-361
-
(1991)
Dev Biol
, vol.144
, pp. 353-361
-
-
Heberlein, U.1
Rubin, G.M.2
-
11
-
-
0034889139
-
Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star
-
Hsiung F, Griffis ER, Pickup A, Powers MA, Moses K (2001) Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star. Mech Dev 107: 13-23
-
(2001)
Mech Dev
, vol.107
, pp. 13-23
-
-
Hsiung, F.1
Griffis, E.R.2
Pickup, A.3
Powers, M.A.4
Moses, K.5
-
12
-
-
0028363844
-
Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila
-
Kolodkin AL, Pickup AT, Lin DM, Goodman CS, Banerjee U (1994) Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila. Development 120: 1731-1745
-
(1994)
Development
, vol.120
, pp. 1731-1745
-
-
Kolodkin, A.L.1
Pickup, A.T.2
Lin, D.M.3
Goodman, C.S.4
Banerjee, U.5
-
13
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
-
Lee JR, Urban S, Garvey CF, Freeman M (2001) Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 107: 161-171
-
(2001)
Cell
, vol.107
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
14
-
-
2442543552
-
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
-
Loewer A, Soba P, Beyreuther K, Paro R, Merdes G (2004) Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development. EMBO Rep 5: 405-411
-
(2004)
EMBO Rep
, vol.5
, pp. 405-411
-
-
Loewer, A.1
Soba, P.2
Beyreuther, K.3
Paro, R.4
Merdes, G.5
-
15
-
-
8144229817
-
Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
-
Merdes G, Soba P, Loewer A, Bilic MV, Beyreuther K, Paro R (2004) Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. EMBO J 23: 4082-4095
-
(2004)
EMBO J
, vol.23
, pp. 4082-4095
-
-
Merdes, G.1
Soba, P.2
Loewer, A.3
Bilic, M.V.4
Beyreuther, K.5
Paro, R.6
-
16
-
-
0037102252
-
Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage
-
Reich A, Shilo BZ (2002) Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J 21: 4287-4296
-
(2002)
EMBO J
, vol.21
, pp. 4287-4296
-
-
Reich, A.1
Shilo, B.Z.2
-
17
-
-
0026687788
-
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis
-
Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N (1992) The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes Dev 6: 1503-1517
-
(1992)
Genes Dev
, vol.6
, pp. 1503-1517
-
-
Rutledge, B.J.1
Zhang, K.2
Bier, E.3
Jan, Y.N.4
Perrimon, N.5
-
18
-
-
5044249045
-
Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila
-
Schlesinger A, Kiger A, Perrimon N, Shilo BZ (2004) Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell 7: 535-545
-
(2004)
Dev Cell
, vol.7
, pp. 535-545
-
-
Schlesinger, A.1
Kiger, A.2
Perrimon, N.3
Shilo, B.Z.4
-
19
-
-
0036796861
-
Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells
-
Schulz C, Wood CG, Jones DL, Tazuke SI, Fuller MT (2002) Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development 129: 4523-4534
-
(2002)
Development
, vol.129
, pp. 4523-4534
-
-
Schulz, C.1
Wood, C.G.2
Jones, D.L.3
Tazuke, S.I.4
Fuller, M.T.5
-
20
-
-
0029100254
-
Inhibition of Drosophila EGF receptor activation by the secreted protein Argos
-
Schweitzer R, Howes R, Smith R, Shilo BZ, Freeman M (1995a) Inhibition of Drosophila EGF receptor activation by the secreted protein Argos. Nature 376: 699-702
-
(1995)
Nature
, vol.376
, pp. 699-702
-
-
Schweitzer, R.1
Howes, R.2
Smith, R.3
Shilo, B.Z.4
Freeman, M.5
-
21
-
-
0029015431
-
Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination
-
Schweitzer R, Shaharabany M, Seger R, Shilo BZ (1995b) Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev 9: 1518-1529
-
(1995)
Genes Dev
, vol.9
, pp. 1518-1529
-
-
Schweitzer, R.1
Shaharabany, M.2
Seger, R.3
Shilo, B.Z.4
-
22
-
-
0242321269
-
Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases
-
Seachrist JL, Ferguson SS (2003) Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases. Life Sci 74: 225-235
-
(2003)
Life Sci
, vol.74
, pp. 225-235
-
-
Seachrist, J.L.1
Ferguson, S.S.2
-
23
-
-
0037429688
-
Signaling by the Drosophila epidermal growth factor receptor pathway during development
-
Shilo BZ (2003) Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp Cell Res 284: 140-149
-
(2003)
Exp Cell Res
, vol.284
, pp. 140-149
-
-
Shilo, B.Z.1
-
24
-
-
26444536535
-
Regulating the dynamics of EGF receptor signaling in space and time
-
Shilo BZ (2005) Regulating the dynamics of EGF receptor signaling in space and time. Development 132: 4017-4027
-
(2005)
Development
, vol.132
, pp. 4017-4027
-
-
Shilo, B.Z.1
-
25
-
-
0034625074
-
LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator
-
Szuts D, Bienz M (2000) LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator. Proc Natl Acad Sci USA 97: 5351-5356
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5351-5356
-
-
Szuts, D.1
Bienz, M.2
-
26
-
-
0037080869
-
Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz
-
Tsruya R, Schlesinger A, Reich A, Gabay L, Sapir A, Shilo BZ (2002) Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes Dev 16: 222-234
-
(2002)
Genes Dev
, vol.16
, pp. 222-234
-
-
Tsruya, R.1
Schlesinger, A.2
Reich, A.3
Gabay, L.4
Sapir, A.5
Shilo, B.Z.6
-
27
-
-
0036777494
-
Intramembrane proteolysis controls diverse signalling pathways throughout evolution
-
Urban S, Freeman M (2002) Intramembrane proteolysis controls diverse signalling pathways throughout evolution. Curr Opin Genet Dev 12: 512-518
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 512-518
-
-
Urban, S.1
Freeman, M.2
-
28
-
-
0038771224
-
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
Urban S, Freeman M (2003) Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Mol Cell 11: 1425-1434
-
(2003)
Mol Cell
, vol.11
, pp. 1425-1434
-
-
Urban, S.1
Freeman, M.2
-
29
-
-
0035913908
-
Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases
-
Urban S, Lee JR, Freeman M (2001) Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases. Cell 107: 173-182
-
(2001)
Cell
, vol.107
, pp. 173-182
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
30
-
-
0037102238
-
A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands
-
Urban S, Lee JR, Freeman M (2002) A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO J 21: 4277-4286
-
(2002)
EMBO J
, vol.21
, pp. 4277-4286
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
31
-
-
33750886311
-
Crystal structure of a rhomboid family intramembrane protease
-
Wang Y, Zhang Y, Ha Y (2006) Crystal structure of a rhomboid family intramembrane protease. Nature 444: 179-180
-
(2006)
Nature
, vol.444
, pp. 179-180
-
-
Wang, Y.1
Zhang, Y.2
Ha, Y.3
-
32
-
-
0034234250
-
A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling
-
Wasserman JD, Urban S, Freeman M (2000) A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling. Genes Dev 14: 1651-1663
-
(2000)
Genes Dev
, vol.14
, pp. 1651-1663
-
-
Wasserman, J.D.1
Urban, S.2
Freeman, M.3
-
33
-
-
4143084775
-
Intramembrane proteolysis: Theme and variations
-
Wolfe MS, Kopan R (2004) Intramembrane proteolysis: theme and variations. Science 305: 1119-1123
-
(2004)
Science
, vol.305
, pp. 1119-1123
-
-
Wolfe, M.S.1
Kopan, R.2
-
34
-
-
33845365770
-
Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry
-
Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y (2006) Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol 13: 1084-1091
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 1084-1091
-
-
Wu, Z.1
Yan, N.2
Feng, L.3
Oberstein, A.4
Yan, H.5
Baker, R.P.6
Gu, L.7
Jeffrey, P.D.8
Urban, S.9
Shi, Y.10
-
35
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110: 489-500
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
Espenshade, P.J.2
Wright, M.E.3
Yabe, D.4
Gong, Y.5
Aebersold, R.6
Goldstein, J.L.7
Brown, M.S.8
|