메뉴 건너뛰기




Volumn 26, Issue 5, 2007, Pages 1211-1220

Rhomboid cleaves Star to regulate the levels of secreted Spitz

Author keywords

EGFR signaling; Intramembrane proteolysis; Rhomboid; Spitz; Star

Indexed keywords

CHAPERONE; EPIDERMAL GROWTH FACTOR RECEPTOR; MEMBRANE PROTEIN; PROTEINASE; RHOMBOID; SPI PROTEIN; STAR PROTEIN; UNCLASSIFIED DRUG;

EID: 33947178517     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601581     Document Type: Article
Times cited : (50)

References (36)
  • 1
    • 33846275257 scopus 로고    scopus 로고
    • Structural basis for intramembrane proteolysis by rhomboid serine proteases
    • Ben-Shem A, Fass D, Bibi E (2007) Structural basis for intramembrane proteolysis by rhomboid serine proteases. Proc Natl Acad Sci USA 104: 462-466
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 462-466
    • Ben-Shem, A.1    Fass, D.2    Bibi, E.3
  • 2
    • 0025060344 scopus 로고
    • rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster
    • Bier E, Jan LY, Jan YN (1990) rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev 4: 190-203
    • (1990) Genes Dev , vol.4 , pp. 190-203
    • Bier, E.1    Jan, L.Y.2    Jan, Y.N.3
  • 4
    • 0142115409 scopus 로고    scopus 로고
    • EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye
    • Brown KE, Freeman M (2003) EGFR signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130: 5401-5412
    • (2003) Development , vol.130 , pp. 5401-5412
    • Brown, K.E.1    Freeman, M.2
  • 5
    • 0030866482 scopus 로고    scopus 로고
    • In situ activation pattern of Drosophila EGF receptor pathway during development
    • Gabay L, Seger R, Shilo BZ (1997) In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277: 1103-1106
    • (1997) Science , vol.277 , pp. 1103-1106
    • Gabay, L.1    Seger, R.2    Shilo, B.Z.3
  • 6
    • 0036339998 scopus 로고    scopus 로고
    • Mechanism of activation of the Drosophila EGF receptor by the TGFalpha ligand Gurken during oogenesis
    • Ghiglione C, Bach EA, Paraiso Y, Carraway III KL, Noselli S, Perrimon N (2002) Mechanism of activation of the Drosophila EGF receptor by the TGFalpha ligand Gurken during oogenesis. Development 129: 175-186
    • (2002) Development , vol.129 , pp. 175-186
    • Ghiglione, C.1    Bach, E.A.2    Paraiso, Y.3    Carraway III, K.L.4    Noselli, S.5    Perrimon, N.6
  • 7
    • 33748432696 scopus 로고    scopus 로고
    • Soma-germline interactions coordinate homeostasis and growth in the Drosophila gonad
    • Gilboa L, Lehmann R (2006) Soma-germline interactions coordinate homeostasis and growth in the Drosophila gonad. Nature 443: 97-100
    • (2006) Nature , vol.443 , pp. 97-100
    • Gilboa, L.1    Lehmann, R.2
  • 8
    • 0029855245 scopus 로고    scopus 로고
    • The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
    • Golembo M, Raz E, Shilo BZ (1996) The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122: 3363-3370
    • (1996) Development , vol.122 , pp. 3363-3370
    • Golembo, M.1    Raz, E.2    Shilo, B.Z.3
  • 9
    • 0034667916 scopus 로고    scopus 로고
    • Brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling
    • Guichard A, Roark M, Ronshaugen M, Bier E (2000) Brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling. Dev Biol 226: 255-266
    • (2000) Dev Biol , vol.226 , pp. 255-266
    • Guichard, A.1    Roark, M.2    Ronshaugen, M.3    Bier, E.4
  • 10
    • 0025796847 scopus 로고
    • Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough
    • Heberlein U, Rubin GM (1991) Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough. Dev Biol 144: 353-361
    • (1991) Dev Biol , vol.144 , pp. 353-361
    • Heberlein, U.1    Rubin, G.M.2
  • 11
    • 0034889139 scopus 로고    scopus 로고
    • Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star
    • Hsiung F, Griffis ER, Pickup A, Powers MA, Moses K (2001) Function of the Drosophila TGF-alpha homolog Spitz is controlled by Star and interacts directly with Star. Mech Dev 107: 13-23
    • (2001) Mech Dev , vol.107 , pp. 13-23
    • Hsiung, F.1    Griffis, E.R.2    Pickup, A.3    Powers, M.A.4    Moses, K.5
  • 12
    • 0028363844 scopus 로고
    • Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila
    • Kolodkin AL, Pickup AT, Lin DM, Goodman CS, Banerjee U (1994) Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila. Development 120: 1731-1745
    • (1994) Development , vol.120 , pp. 1731-1745
    • Kolodkin, A.L.1    Pickup, A.T.2    Lin, D.M.3    Goodman, C.S.4    Banerjee, U.5
  • 13
    • 0035913906 scopus 로고    scopus 로고
    • Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
    • Lee JR, Urban S, Garvey CF, Freeman M (2001) Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 107: 161-171
    • (2001) Cell , vol.107 , pp. 161-171
    • Lee, J.R.1    Urban, S.2    Garvey, C.F.3    Freeman, M.4
  • 14
    • 2442543552 scopus 로고    scopus 로고
    • Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
    • Loewer A, Soba P, Beyreuther K, Paro R, Merdes G (2004) Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development. EMBO Rep 5: 405-411
    • (2004) EMBO Rep , vol.5 , pp. 405-411
    • Loewer, A.1    Soba, P.2    Beyreuther, K.3    Paro, R.4    Merdes, G.5
  • 15
    • 8144229817 scopus 로고    scopus 로고
    • Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
    • Merdes G, Soba P, Loewer A, Bilic MV, Beyreuther K, Paro R (2004) Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. EMBO J 23: 4082-4095
    • (2004) EMBO J , vol.23 , pp. 4082-4095
    • Merdes, G.1    Soba, P.2    Loewer, A.3    Bilic, M.V.4    Beyreuther, K.5    Paro, R.6
  • 16
    • 0037102252 scopus 로고    scopus 로고
    • Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage
    • Reich A, Shilo BZ (2002) Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J 21: 4287-4296
    • (2002) EMBO J , vol.21 , pp. 4287-4296
    • Reich, A.1    Shilo, B.Z.2
  • 17
    • 0026687788 scopus 로고
    • The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis
    • Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N (1992) The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes Dev 6: 1503-1517
    • (1992) Genes Dev , vol.6 , pp. 1503-1517
    • Rutledge, B.J.1    Zhang, K.2    Bier, E.3    Jan, Y.N.4    Perrimon, N.5
  • 18
    • 5044249045 scopus 로고    scopus 로고
    • Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila
    • Schlesinger A, Kiger A, Perrimon N, Shilo BZ (2004) Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell 7: 535-545
    • (2004) Dev Cell , vol.7 , pp. 535-545
    • Schlesinger, A.1    Kiger, A.2    Perrimon, N.3    Shilo, B.Z.4
  • 19
    • 0036796861 scopus 로고    scopus 로고
    • Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells
    • Schulz C, Wood CG, Jones DL, Tazuke SI, Fuller MT (2002) Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development 129: 4523-4534
    • (2002) Development , vol.129 , pp. 4523-4534
    • Schulz, C.1    Wood, C.G.2    Jones, D.L.3    Tazuke, S.I.4    Fuller, M.T.5
  • 20
    • 0029100254 scopus 로고
    • Inhibition of Drosophila EGF receptor activation by the secreted protein Argos
    • Schweitzer R, Howes R, Smith R, Shilo BZ, Freeman M (1995a) Inhibition of Drosophila EGF receptor activation by the secreted protein Argos. Nature 376: 699-702
    • (1995) Nature , vol.376 , pp. 699-702
    • Schweitzer, R.1    Howes, R.2    Smith, R.3    Shilo, B.Z.4    Freeman, M.5
  • 21
    • 0029015431 scopus 로고
    • Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination
    • Schweitzer R, Shaharabany M, Seger R, Shilo BZ (1995b) Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev 9: 1518-1529
    • (1995) Genes Dev , vol.9 , pp. 1518-1529
    • Schweitzer, R.1    Shaharabany, M.2    Seger, R.3    Shilo, B.Z.4
  • 22
    • 0242321269 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases
    • Seachrist JL, Ferguson SS (2003) Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases. Life Sci 74: 225-235
    • (2003) Life Sci , vol.74 , pp. 225-235
    • Seachrist, J.L.1    Ferguson, S.S.2
  • 23
    • 0037429688 scopus 로고    scopus 로고
    • Signaling by the Drosophila epidermal growth factor receptor pathway during development
    • Shilo BZ (2003) Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp Cell Res 284: 140-149
    • (2003) Exp Cell Res , vol.284 , pp. 140-149
    • Shilo, B.Z.1
  • 24
    • 26444536535 scopus 로고    scopus 로고
    • Regulating the dynamics of EGF receptor signaling in space and time
    • Shilo BZ (2005) Regulating the dynamics of EGF receptor signaling in space and time. Development 132: 4017-4027
    • (2005) Development , vol.132 , pp. 4017-4027
    • Shilo, B.Z.1
  • 25
    • 0034625074 scopus 로고    scopus 로고
    • LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator
    • Szuts D, Bienz M (2000) LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator. Proc Natl Acad Sci USA 97: 5351-5356
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5351-5356
    • Szuts, D.1    Bienz, M.2
  • 26
    • 0037080869 scopus 로고    scopus 로고
    • Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz
    • Tsruya R, Schlesinger A, Reich A, Gabay L, Sapir A, Shilo BZ (2002) Intracellular trafficking by Star regulates cleavage of the Drosophila EGF receptor ligand Spitz. Genes Dev 16: 222-234
    • (2002) Genes Dev , vol.16 , pp. 222-234
    • Tsruya, R.1    Schlesinger, A.2    Reich, A.3    Gabay, L.4    Sapir, A.5    Shilo, B.Z.6
  • 27
    • 0036777494 scopus 로고    scopus 로고
    • Intramembrane proteolysis controls diverse signalling pathways throughout evolution
    • Urban S, Freeman M (2002) Intramembrane proteolysis controls diverse signalling pathways throughout evolution. Curr Opin Genet Dev 12: 512-518
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 512-518
    • Urban, S.1    Freeman, M.2
  • 28
    • 0038771224 scopus 로고    scopus 로고
    • Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
    • Urban S, Freeman M (2003) Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Mol Cell 11: 1425-1434
    • (2003) Mol Cell , vol.11 , pp. 1425-1434
    • Urban, S.1    Freeman, M.2
  • 29
    • 0035913908 scopus 로고    scopus 로고
    • Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases
    • Urban S, Lee JR, Freeman M (2001) Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases. Cell 107: 173-182
    • (2001) Cell , vol.107 , pp. 173-182
    • Urban, S.1    Lee, J.R.2    Freeman, M.3
  • 30
    • 0037102238 scopus 로고    scopus 로고
    • A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands
    • Urban S, Lee JR, Freeman M (2002) A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO J 21: 4277-4286
    • (2002) EMBO J , vol.21 , pp. 4277-4286
    • Urban, S.1    Lee, J.R.2    Freeman, M.3
  • 31
    • 33750886311 scopus 로고    scopus 로고
    • Crystal structure of a rhomboid family intramembrane protease
    • Wang Y, Zhang Y, Ha Y (2006) Crystal structure of a rhomboid family intramembrane protease. Nature 444: 179-180
    • (2006) Nature , vol.444 , pp. 179-180
    • Wang, Y.1    Zhang, Y.2    Ha, Y.3
  • 32
    • 0034234250 scopus 로고    scopus 로고
    • A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling
    • Wasserman JD, Urban S, Freeman M (2000) A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling. Genes Dev 14: 1651-1663
    • (2000) Genes Dev , vol.14 , pp. 1651-1663
    • Wasserman, J.D.1    Urban, S.2    Freeman, M.3
  • 33
    • 4143084775 scopus 로고    scopus 로고
    • Intramembrane proteolysis: Theme and variations
    • Wolfe MS, Kopan R (2004) Intramembrane proteolysis: theme and variations. Science 305: 1119-1123
    • (2004) Science , vol.305 , pp. 1119-1123
    • Wolfe, M.S.1    Kopan, R.2
  • 35
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110: 489-500
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 36
    • 0035257013 scopus 로고    scopus 로고
    • Rab proteins as membrane organizers
    • Zerial M, McBride H (2001) Rab proteins as membrane organizers. Nat Rev Mol Cell Biol 2: 107-117
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 107-117
    • Zerial, M.1    McBride, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.