Ginsenoside Rg1 attenuates okadaic acid induced spatial memory impairment by the GSK3β/tau signaling pathway and the Aβ formation prevention in rats

European Journal of Pharmacology

Volumn 710, Issue 1-3, 2013, Pages 29-38

  Song, Xiu Yun ^a   Hu, Jin Feng ^b   Chu, Shi Feng ^a   Zhang, Zhao ^a   Xu, Shuang ^a   Yuan, Yu He ^a   Han, Ning ^a   Liu, Yan ^a   Niu, Fei ^a   He, Xin ^a   Chen, Nai Hong ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study   (China)

Author keywords

A formation; Ginsenoside Rg1; GSK3 tau signaling pathway; Memory impairment; Morris water maze; Okadaic acid

Indexed keywords

AMYLOID BETA PROTEIN; DONEPEZIL; GINSENOSIDE RG 1; GLYCOGEN SYNTHASE KINASE 3; OKADAIC ACID; TAU PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MAZE TEST; MEMORY CONSOLIDATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; ORIENTATION; PARIETAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPATIAL MEMORY; WESTERN BLOTTING;

ALZHEIMER DISEASE; ANIMALS; GINSENOSIDES; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; NEUROPROTECTIVE AGENTS; OKADAIC ACID; PARIETAL LOBE; RATS; RATS, SPRAGUE-DAWLEY; TAU PROTEINS;

EID: 84878256457     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.03.051     Document Type: Article

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