메뉴 건너뛰기




Volumn 30, Issue 8, 2005, Pages 1511-1520

Olanzapine attenuates the okadaic acid-induced spatial memory impairment and hippocampal cell death in rats

Author keywords

Cell death; Hippocampus; Memory; Neuroprotection; Okadaic acid; Olanzapine

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; OKADAIC ACID; OLANZAPINE; URIDINE TRIPHOSPHATE;

EID: 23844547937     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300757     Document Type: Article
Times cited : (40)

References (61)
  • 1
    • 13844264900 scopus 로고    scopus 로고
    • Selective neurotoxic damage to the hippocampal formation impairs performance of the transverse patterning and location memory tasks in rhesus macaques
    • Alvarado MC, Bachevalier J (2005). Selective neurotoxic damage to the hippocampal formation impairs performance of the transverse patterning and location memory tasks in rhesus macaques. Hippocampus 15: 118-131.
    • (2005) Hippocampus , vol.15 , pp. 118-131
    • Alvarado, M.C.1    Bachevalier, J.2
  • 2
    • 0028786849 scopus 로고
    • Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A
    • Arendt T, Holzer M, Fruth R, Bruckner MK, Gartner U (1995). Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A. Neuroscience 69: 691-698.
    • (1995) Neuroscience , vol.69 , pp. 691-698
    • Arendt, T.1    Holzer, M.2    Fruth, R.3    Bruckner, M.K.4    Gartner, U.5
  • 3
    • 0031596660 scopus 로고    scopus 로고
    • Phosphorylation of tau, Aβ-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A
    • Arendt T, Holzer M, Fruth R, Bruckner MK, Gartner U (1998). Phosphorylation of tau, Aβ-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A. Neurobiol Aging 19: 3-13.
    • (1998) Neurobiol Aging , vol.19 , pp. 3-13
    • Arendt, T.1    Holzer, M.2    Fruth, R.3    Bruckner, M.K.4    Gartner, U.5
  • 4
    • 0032191966 scopus 로고    scopus 로고
    • The protein phosphatase inhibitor okadaic acid induces heat shock protein expression and neurodegeneration in rat hippocampus in vivo
    • Arias C, Becerra-Garcia F, Arrieta I, Tapia R (1998). The protein phosphatase inhibitor okadaic acid induces heat shock protein expression and neurodegeneration in rat hippocampus in vivo. Exp Neurol 153: 242-254.
    • (1998) Exp Neurol , vol.153 , pp. 242-254
    • Arias, C.1    Becerra-Garcia, F.2    Arrieta, I.3    Tapia, R.4
  • 5
    • 0027162369 scopus 로고
    • Okadaic acid induced early changes in microtubule-associated protein 2 and tau phosphorylation prior to neurodegeneration in cultured cortical neurons
    • Arias C, Sharma N, Davies P, Shafit-Zagardo B (1993). Okadaic acid induced early changes in microtubule-associated protein 2 and tau phosphorylation prior to neurodegeneration in cultured cortical neurons. J Neurochem 61: 673-682.
    • (1993) J Neurochem , vol.61 , pp. 673-682
    • Arias, C.1    Sharma, N.2    Davies, P.3    Shafit-Zagardo, B.4
  • 6
    • 0029757375 scopus 로고    scopus 로고
    • Recent advances in defining the neuropathology of schizophrenia
    • Arnold SE, Trojanowski JQ (1996). Recent advances in defining the neuropathology of schizophrenia. Acta Neuropathol 92: 217-231.
    • (1996) Acta Neuropathol , vol.92 , pp. 217-231
    • Arnold, S.E.1    Trojanowski, J.Q.2
  • 7
    • 0037215386 scopus 로고    scopus 로고
    • Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs
    • Bai O, Chlan-Fourney J, Bowen R, Keegan D, Li XM (2003). Expression of brain-derived neurotrophic factor mRNA in rat hippocampus after treatment with antipsychotic drugs. J Neurosci Res 71: 127-131.
    • (2003) J Neurosci Res , vol.71 , pp. 127-131
    • Bai, O.1    Chlan-Fourney, J.2    Bowen, R.3    Keegan, D.4    Li, X.M.5
  • 8
    • 2342451962 scopus 로고    scopus 로고
    • Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus
    • Bai O, Zhang H, Li XM (2004). Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus. Brain Res 1010: 81-86.
    • (2004) Brain Res , vol.1010 , pp. 81-86
    • Bai, O.1    Zhang, H.2    Li, X.M.3
  • 10
    • 1842330245 scopus 로고    scopus 로고
    • Efficacy of olanzapine: An overview of pivotal clinical trials
    • Beasley CM, Tollefson GD, Tran PV (1997). Efficacy of olanzapine: an overview of pivotal clinical trials. J Clin Psychiatry 58: 7-12.
    • (1997) J Clin Psychiatry , vol.58 , pp. 7-12
    • Beasley, C.M.1    Tollefson, G.D.2    Tran, P.V.3
  • 11
    • 0030873361 scopus 로고    scopus 로고
    • Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L)
    • Benito A, Lerga A, Silva M, Leon J, Fernandez-Luna JL (1997). Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L). Leukemia 11: 940-944.
    • (1997) Leukemia , vol.11 , pp. 940-944
    • Benito, A.1    Lerga, A.2    Silva, M.3    Leon, J.4    Fernandez-Luna, J.L.5
  • 13
    • 0036268294 scopus 로고    scopus 로고
    • Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder
    • Bilder RM, Goldman RS, Volavka J, Czobor P, Hoptman M, Sheitman B et al (2002). Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder. Am J Psychiatry 159: 1018-1028.
    • (2002) Am J Psychiatry , vol.159 , pp. 1018-1028
    • Bilder, R.M.1    Goldman, R.S.2    Volavka, J.3    Czobor, P.4    Hoptman, M.5    Sheitman, B.6
  • 14
    • 0025823502 scopus 로고
    • The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cell
    • Boe R, Gjertsen BT, Vintermyr OK, Houge G, Lanotte M, Doskeland SO (1991). The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cell. Exp Cell Res 195: 237-246.
    • (1991) Exp Cell Res , vol.195 , pp. 237-246
    • Boe, R.1    Gjertsen, B.T.2    Vintermyr, O.K.3    Houge, G.4    Lanotte, M.5    Doskeland, S.O.6
  • 15
    • 1542283580 scopus 로고    scopus 로고
    • Cytoskeletal disruption is the key factor that triggers apoptosis in okadaic acid-treated neuroblastoma cells
    • Cabado AG, Leira F, Vieytes MR, Vieites JM, Botana LM (2004). Cytoskeletal disruption is the key factor that triggers apoptosis in okadaic acid-treated neuroblastoma cells. Arch Toxicol 78: 74-85.
    • (2004) Arch Toxicol , vol.78 , pp. 74-85
    • Cabado, A.G.1    Leira, F.2    Vieytes, M.R.3    Vieites, J.M.4    Botana, L.M.5
  • 16
    • 0030093869 scopus 로고    scopus 로고
    • Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8 and H-9
    • Cagnolli CM, Kharlamov E, Atabay C, Uz T, Manev H (1996). Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8 and H-9. J Mol Neurosci 7: 65-76.
    • (1996) J Mol Neurosci , vol.7 , pp. 65-76
    • Cagnolli, C.M.1    Kharlamov, E.2    Atabay, C.3    Uz, T.4    Manev, H.5
  • 17
    • 0030816278 scopus 로고    scopus 로고
    • The relationship of pharmacology to side effects
    • Casey DE (1997). The relationship of pharmacology to side effects. J Clin Psychiatry 58: s55-s62.
    • (1997) J Clin Psychiatry , vol.58
    • Casey, D.E.1
  • 18
    • 0025181418 scopus 로고
    • Okadaic acid: A new probe for the study of cellular regulation
    • Cohen P, Holmes CF, Tsukitani Y (1990). Okadaic acid: a new probe for the study of cellular regulation. Trends Biol Sci 15: 98-102.
    • (1990) Trends Biol Sci , vol.15 , pp. 98-102
    • Cohen, P.1    Holmes, C.F.2    Tsukitani, Y.3
  • 19
    • 0035280269 scopus 로고    scopus 로고
    • Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: A longitudinal study
    • Cuesta MJ, Peralta V, Zarzuela A (2001). Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal study. Schizophr Res 48: 17-28.
    • (2001) Schizophr Res , vol.48 , pp. 17-28
    • Cuesta, M.J.1    Peralta, V.2    Zarzuela, A.3
  • 20
    • 0030798020 scopus 로고    scopus 로고
    • Schizophrenia as a chronic active brain process: A study of progressive brain structural change subsequent to the onset of schizophrenia
    • DeLisi LE, Sakuma M, Rew W, Kushner M, Hoff AL, Crimson R (1997). Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia. Psychiatry Res 74: 129-140.
    • (1997) Psychiatry Res , vol.74 , pp. 129-140
    • DeLisi, L.E.1    Sakuma, M.2    Rew, W.3    Kushner, M.4    Hoff, A.L.5    Crimson, R.6
  • 21
    • 0031016120 scopus 로고    scopus 로고
    • Olanzapine. A review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses
    • Fulton B, Goa KL (1997). Olanzapine. A review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses. Drugs 53: 281-298.
    • (1997) Drugs , vol.53 , pp. 281-298
    • Fulton, B.1    Goa, K.L.2
  • 22
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J cell Biol 119: 493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 23
    • 0029918481 scopus 로고    scopus 로고
    • What are the functional consequences of neurocognitive deficits in schizophrenia?
    • Green MF (1996). What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 153: 321-330.
    • (1996) Am J Psychiatry , vol.153 , pp. 321-330
    • Green, M.F.1
  • 25
    • 0342813507 scopus 로고    scopus 로고
    • Schizophrenia and related disorders in late life
    • Bellack AS, Hersen M (eds). Elsevier: Amsterdam
    • Harvey PD (1998). Schizophrenia and related disorders in late life. In: Bellack AS, Hersen M (eds). Comprehensive Clinical Psychology. Elsevier: Amsterdam. Vol 8, pp 74-86.
    • (1998) Comprehensive Clinical Psychology , vol.8 , pp. 74-86
    • Harvey, P.D.1
  • 26
    • 0141993537 scopus 로고    scopus 로고
    • Changes in cognitive functioning with risperidone and olanzapine treatment: A large-scale, double-blind, randomized study
    • Harvey PD, Green MF, McGurk SR, Meltzer HY (2003). Changes in cognitive functioning with risperidone and olanzapine treatment: a large-scale, double-blind, randomized study. Psychopharmacology 169: 404-411.
    • (2003) Psychopharmacology , vol.169 , pp. 404-411
    • Harvey, P.D.1    Green, M.F.2    McGurk, S.R.3    Meltzer, H.Y.4
  • 27
    • 3343019119 scopus 로고    scopus 로고
    • Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats
    • He J, Xu H, Yang Y, Zhang X, Li XM (2004). Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats. Brain Res 1018: 186-192.
    • (2004) Brain Res , vol.1018 , pp. 186-192
    • He, J.1    Xu, H.2    Yang, Y.3    Zhang, X.4    Li, X.M.5
  • 28
    • 0036150145 scopus 로고    scopus 로고
    • A role of Fos expression in the CA3 region of the hippocampus in spatial memory formation in rats
    • He J, Yamada K, Nabeshima T (2002a). A role of Fos expression in the CA3 region of the hippocampus in spatial memory formation in rats. Neuropsychopharmacology 26: 259-268.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 259-268
    • He, J.1    Yamada, K.2    Nabeshima, T.3
  • 29
    • 0035666080 scopus 로고    scopus 로고
    • Spatial memory deficit and neurodegeneration induced by the direct injection of okadaic acid into the hippocampus in rats
    • He J, Yamada K, Zou L, Nabeshima T (2001). Spatial memory deficit and neurodegeneration induced by the direct injection of okadaic acid into the hippocampus in rats. J Neural Transm 108: 1435-1443.
    • (2001) J Neural Transm , vol.108 , pp. 1435-1443
    • He, J.1    Yamada, K.2    Zou, L.3    Nabeshima, T.4
  • 30
    • 0037151266 scopus 로고    scopus 로고
    • Learning and memory in two different reward tasks in a radial arm maze in rats
    • He J, Yamada K, Zou L, Nakajima A, Kamei H, Nabeshima T (2002b). Learning and memory in two different reward tasks in a radial arm maze in rats. Behav Brain Res 134: 139-148.
    • (2002) Behav Brain Res , vol.134 , pp. 139-148
    • He, J.1    Yamada, K.2    Zou, L.3    Nakajima, A.4    Kamei, H.5    Nabeshima, T.6
  • 31
    • 0037032594 scopus 로고    scopus 로고
    • Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death
    • Hong HN, Yoon SY, Suh J, Lee JH, Kim D (2002). Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death. Neurosci lett 334: 63-67.
    • (2002) Neurosci Lett , vol.334 , pp. 63-67
    • Hong, H.N.1    Yoon, S.Y.2    Suh, J.3    Lee, J.H.4    Kim, D.5
  • 32
    • 0036176263 scopus 로고    scopus 로고
    • Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum
    • Ichikawa J, Dai J, O'Laughlin IA, Fowler WL, Meltzer HY (2002). Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum. Neuropsychopharmacology 26: 325-339.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 325-339
    • Ichikawa, J.1    Dai, J.2    O'Laughlin, I.A.3    Fowler, W.L.4    Meltzer, H.Y.5
  • 35
    • 0033118431 scopus 로고    scopus 로고
    • Differential effects of Olanzapine on the gene expression of superoxide dismutase and low affinity nerve growth factor receptor
    • Li X-M, Chlan-Fourney J, Bennett V, Shrikhande S, Juorio AV, Keegan D et al (1999). Differential effects of Olanzapine on the gene expression of superoxide dismutase and low affinity nerve growth factor receptor. J Neurosci Res 56: 72-75.
    • (1999) J Neurosci Res , vol.56 , pp. 72-75
    • Li, X.-M.1    Chlan-Fourney, J.2    Bennett, V.3    Shrikhande, S.4    Juorio, A.V.5    Keegan, D.6
  • 36
    • 5344262388 scopus 로고    scopus 로고
    • Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: Effect of chronic administration of olanzapine
    • Luo C, Xu H, Li XM (2004). Post-stress changes in BDNF and Bcl-2 immunoreactivities in hippocampal neurons: effect of chronic administration of olanzapine. Brain Res 1025: 194-202.
    • (2004) Brain Res , vol.1025 , pp. 194-202
    • Luo, C.1    Xu, H.2    Li, X.M.3
  • 37
    • 0032557458 scopus 로고    scopus 로고
    • Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1
    • Manna SK, Zhang HJ, Yan T, oberley LW, Aggarwal BB (1998). Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. J Biol Chem 273: 13245-13254.
    • (1998) J Biol Chem , vol.273 , pp. 13245-13254
    • Manna, S.K.1    Zhang, H.J.2    Yan, T.3    Oberley, L.W.4    Aggarwal, B.B.5
  • 38
    • 0032736395 scopus 로고    scopus 로고
    • Oxygen reactive radicals production in cell culture by okadaic acid and their implication in protein synthesis inhibition
    • Matias WG, Traore A, Bonini M, Sanni A, Creppy EE (1999). Oxygen reactive radicals production in cell culture by okadaic acid and their implication in protein synthesis inhibition. Hum Exp Toxicol 18: 634-639.
    • (1999) Hum Exp Toxicol , vol.18 , pp. 634-639
    • Matias, W.G.1    Traore, A.2    Bonini, M.3    Sanni, A.4    Creppy, E.E.5
  • 39
    • 0034666119 scopus 로고    scopus 로고
    • Involvement of BDNF in spatial memory formation and maintenance in a radial arm maze test in rats
    • Mizuno M, Yamada K, Olariu A, Nawa H, Nabeshima T (2000). Involvement of BDNF in spatial memory formation and maintenance in a radial arm maze test in rats. J Neurosci 20: 7116-7121.
    • (2000) J Neurosci , vol.20 , pp. 7116-7121
    • Mizuno, M.1    Yamada, K.2    Olariu, A.3    Nawa, H.4    Nabeshima, T.5
  • 40
    • 0032857099 scopus 로고    scopus 로고
    • Influence of olanzapine on cognitive functions and catalepsy in rats after single and chronic administration
    • Nowakowska E, Chodera A, Kus K (1999). Influence of olanzapine on cognitive functions and catalepsy in rats after single and chronic administration. Pol J Pharmacol 51: 295-300.
    • (1999) Pol J Pharmacol , vol.51 , pp. 295-300
    • Nowakowska, E.1    Chodera, A.2    Kus, K.3
  • 44
    • 0034095251 scopus 로고    scopus 로고
    • Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol
    • Purdon SE, Jones BDW, Stip E, Labelle A, Addington D, David SR et al (2000). Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol. Arch Gen Psychiatry 57: 249-258.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 249-258
    • Purdon, S.E.1    Jones, B.D.W.2    Stip, E.3    Labelle, A.4    Addington, D.5    David, S.R.6
  • 46
    • 16244388972 scopus 로고    scopus 로고
    • BDNF protects against stress-induced impairments in spatial learning and memory and LTP
    • Radecki DT, Brown LM, Martinez J, Teyler TJ (2005). BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus 15: 246-253.
    • (2005) Hippocampus , vol.15 , pp. 246-253
    • Radecki, D.T.1    Brown, L.M.2    Martinez, J.3    Teyler, T.J.4
  • 47
    • 0141705359 scopus 로고    scopus 로고
    • Epilepsy, neurodegeneration, and extracellular glutamate in the hippocampus of awake and anesthetized rats treated with okadaic acid
    • Ramirez-Munguia N, Vera G, Tapia R (2003). Epilepsy, neurodegeneration, and extracellular glutamate in the hippocampus of awake and anesthetized rats treated with okadaic acid. Neurochem Res 28: 1517-1524.
    • (2003) Neurochem Res , vol.28 , pp. 1517-1524
    • Ramirez-Munguia, N.1    Vera, G.2    Tapia, R.3
  • 48
    • 0032544721 scopus 로고    scopus 로고
    • Okadaic acid-induced apoptosis of HL60 leukemia cells is preceded by destabilization of bcl-2 mRNA and down-regulation of bcl-2 protein
    • Riordan FA, Foroni L, Hoffbrand AV, Mehta AB, Wickremasinghe RG. (1998). Okadaic acid-induced apoptosis of HL60 leukemia cells is preceded by destabilization of bcl-2 mRNA and down-regulation of bcl-2 protein. FEBS Lett 435: 195-198.
    • (1998) FEBS Lett , vol.435 , pp. 195-198
    • Riordan, F.A.1    Foroni, L.2    Hoffbrand, A.V.3    Mehta, A.B.4    Wickremasinghe, R.G.5
  • 49
    • 0036201186 scopus 로고    scopus 로고
    • Effects of typical and atypical antipsychotics and receptor selective compounds on acetycholine efflux in the hippocampus of the rat
    • Shirazi-Southall S, Rodriguez DE, Nomikos GG (2002). Effects of typical and atypical antipsychotics and receptor selective compounds on acetycholine efflux in the hippocampus of the rat. Neuropsychopharmacology 26: 583-594.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 583-594
    • Shirazi-Southall, S.1    Rodriguez, D.E.2    Nomikos, G.G.3
  • 50
    • 3142658612 scopus 로고    scopus 로고
    • Hippocampal function in cognition
    • Sweatt JD (2004). Hippocampal function in cognition. Psychopharmacology 174: 99-110.
    • (2004) Psychopharmacology , vol.174 , pp. 99-110
    • Sweatt, J.D.1
  • 51
    • 2942642325 scopus 로고    scopus 로고
    • Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit
    • Tian Q, Lin Z-Q, Wang X-C, Chen J, Wang Q, Gong C-X et al (2004). Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit. Neuroscience 126: 277-284.
    • (2004) Neuroscience , vol.126 , pp. 277-284
    • Tian, Q.1    Lin, Z.-Q.2    Wang, X.-C.3    Chen, J.4    Wang, Q.5    Gong, C.-X.6
  • 52
    • 0031777135 scopus 로고    scopus 로고
    • Acute or chronic administration of okadaic acid to rats induces brain damage rather than Alzheimer-like neuropathology
    • Van Dam A-M, Bol JGJM, Binnekade R, Van Muiswinkel FL (1998). Acute or chronic administration of okadaic acid to rats induces brain damage rather than Alzheimer-like neuropathology. Neuroscience 85: 1333-1335.
    • (1998) Neuroscience , vol.85 , pp. 1333-1335
    • Van Dam, A.-M.1    Bol, J.G.J.M.2    Binnekade, R.3    Van Muiswinkel, F.L.4
  • 53
    • 0026091823 scopus 로고
    • The age differences of MRI abnormalities in schizophrenia suggest early ventricular enlargement but later prominence of cortical atrophy
    • Waddington JL, O'Callaghan E, Buckley P, Larkin C, Redmond O, Stack J et al (1991). The age differences of MRI abnormalities in schizophrenia suggest early ventricular enlargement but later prominence of cortical atrophy. Schizophr Res 5: 188-189.
    • (1991) Schizophr Res , vol.5 , pp. 188-189
    • Waddington, J.L.1    O'Callaghan, E.2    Buckley, P.3    Larkin, C.4    Redmond, O.5    Stack, J.6
  • 54
    • 0033945357 scopus 로고    scopus 로고
    • Mechanisms of AT-methyl-D-aspartate-induced apoptosis in phencyclidine-treated cultured forebrain neurons
    • Wang C, Kaufmann JA, Sanchez-Ross MG, Johnson KM (2000). Mechanisms of AT-methyl-D-aspartate-induced apoptosis in phencyclidine-treated cultured forebrain neurons. J Pharmacol Exp Ther 294: 287-295.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 287-295
    • Wang, C.1    Kaufmann, J.A.2    Sanchez-Ross, M.G.3    Johnson, K.M.4
  • 55
    • 0043173819 scopus 로고    scopus 로고
    • Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide
    • Wei Z, Bai O, Richardson JS, Mousseau DD, Li X-M (2003a). Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide. J Neurosci Res 73: 364-368.
    • (2003) J Neurosci Res , vol.73 , pp. 364-368
    • Wei, Z.1    Bai, O.2    Richardson, J.S.3    Mousseau, D.D.4    Li, X.-M.5
  • 57
    • 0041737724 scopus 로고    scopus 로고
    • Comparison of the effects of antipsychotics on a delayed radial maze task in the rat
    • Wolff MC, Leander JD (2003). Comparison of the effects of antipsychotics on a delayed radial maze task in the rat. Psychopharmacology 168: 410-416.
    • (2003) Psychopharmacology , vol.168 , pp. 410-416
    • Wolff, M.C.1    Leander, J.D.2
  • 58
    • 0025062555 scopus 로고
    • Progressive ventricular enlargement in schizophrenia: Comparison to bipolar disorder and correlation with clinical course
    • Woods BT, Yurgelun-Todd D, Benes FM, Frankenburg FR, Pope HG, McSparren J (1990). Progressive ventricular enlargement in schizophrenia: comparison to bipolar disorder and correlation with clinical course. Biol Psychiatry 27: 341-352.
    • (1990) Biol Psychiatry , vol.27 , pp. 341-352
    • Woods, B.T.1    Yurgelun-Todd, D.2    Benes, F.M.3    Frankenburg, F.R.4    Pope, H.G.5    McSparren, J.6
  • 60
    • 0028936252 scopus 로고
    • The impairment of long-term memory formation by the phosphatase inhibitor okadaic acid
    • Zhao WQ, Bennett P, Sedman GL (1995). The impairment of long-term memory formation by the phosphatase inhibitor okadaic acid. Brain Res Bull 36: 557-561.
    • (1995) Brain Res Bull , vol.36 , pp. 557-561
    • Zhao, W.Q.1    Bennett, P.2    Sedman, G.L.3
  • 61
    • 0032029111 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats
    • Zou L-B, Yamada K, Tanaka K, Kameyama T, Nabeshima T (1998). Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in rats. Neuropharmacology 37: 323-330.
    • (1998) Neuropharmacology , vol.37 , pp. 323-330
    • Zou, L.-B.1    Yamada, K.2    Tanaka, K.3    Kameyama, T.4    Nabeshima, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.