Biochemical analysis of active site mutations of human polymerase η

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 745-746, Issue , 2013, Pages 46-54

  Suarez, Samuel C ^a   Beardslee, Renee A ^a   Toffton, Shannon M ^a   McCulloch, Scott D ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

8 oxoG; DNA damage; DNA polymerase ; Mutagenesis; Thymine thymine CPD; Translesion synthesis

Indexed keywords

8 HYDROXYGUANINE; AMINO ACID; DNA; DNA DIRECTED DNA POLYMERASE ETA; MUTANT PROTEIN; PYRIMIDINE DIMER; THYMINE;

AMINO ACID SUBSTITUTION; ARTICLE; BIOCHEMISTRY; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION;

AMINO ACID SUBSTITUTION; BASE SEQUENCE; CATALYTIC DOMAIN; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PYRIMIDINE DIMERS; TEMPLATES, GENETIC;

EID: 84878226044     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2013.03.001     Document Type: Article

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