A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 50, 2012, Pages 20401-20406

  Markkanen, Enni ^a   Castrec, Benoît ^a   Villani, Giuseppe ^b   Hübscher, Ulrich ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

DNA polymerase switch; DNA repair; DNA replication

Indexed keywords

8 HYDROXYGUANINE; ADENINE; CYTOSINE; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE KAPPA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA REPAIR; EMBRYO; EMBRYO DEVELOPMENT; ENZYME SPECIFICITY; ERROR; ERROR FREE BYPASS; FIBROBLAST; GENE MUTATION; GENE REPLICATION; GENE SWITCHING; HELA CELL; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; SYNTHESIS; TRANSLESION SYNTHESIS;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA; DNA POLYMERASE BETA; DNA POLYMERASE III; DNA REPAIR; DNA REPLICATION; GUANINE; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; RNA, SMALL INTERFERING;

EID: 84870880802     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211532109     Document Type: Article

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