Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

Nature Structural and Molecular Biology

Volumn 19, Issue 6, 2012, Pages 628-632

  Ummat, Ajay ^a   Rechkoblit, Olga ^a   Jain, Rinku ^a   Roy Choudhury, Jayati ^b   Johnson, Robert E ^b   Silverstein, Timothy D ^a   Buku, Angeliki ^a   Lone, Samer ^a   Prakash, Louise ^b   Prakash, Satya ^b   Aggarwal, Aneel K ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DEOXYCYTIDINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE ETA; GUANINE; THYMINE;

ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; DNA DAMAGE; DNA STRAND; DRUG SPECIFICITY; GEOMETRY; NEOPLASM; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; CATALYTIC DOMAIN; CISPLATIN; CRYSTALLOGRAPHY, X-RAY; DEOXYCYTOSINE NUCLEOTIDES; DNA ADDUCTS; DNA-DIRECTED DNA POLYMERASE; HUMANS; MODELS, MOLECULAR; NEOPLASMS; SUBSTRATE SPECIFICITY;

EID: 84861887954     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2295     Document Type: Article

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