Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 21, 2013, Pages 8477-8482

  Thomsen, Nathan D ^a   Koerber, James T ^a   Wells, James A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allostery; Cell death; Fab; Phage display; Protease

Indexed keywords

CASPASE; ENZYME PRECURSOR; HETERODIMER; PROCASPASE 3; PROCASPASE 7; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; PRIORITY JOURNAL;

ALLOSTERY; CELL DEATH; FAB; PHAGE DISPLAY; PROTEASE;

APOPTOSIS; CASPASE 3; CASPASE 7; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878145247     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306759110     Document Type: Article

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