Global kinetic analysis of proteolysis via quantitative targeted proteomics

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 6, 2012, Pages 1913-1918

  Agard, Nicholas J ^a,b   Mahrus, Sami ^a,c   Trinidad, Jonathan C ^a   Lynn, Aenoch ^a,d   Burlingame, Alma L ^a   Wells, James A ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b R and D Project Development and Management   (United States)

^c GENENTECH INC   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Caspase; Enzymology; Mass spectrometry; Selected reaction monitoring

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; PEPTIDE; STAUROSPORINE;

APOPTOSIS; ARTICLE; CATALYSIS; CELL LYSATE; CELL STRUCTURE; HYDROLYSIS; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN TARGETING; PROTEOMICS; QUANTITATIVE ANALYSIS;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASES; CELL SURVIVAL; ENDOCYTOSIS; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; KINETICS; MICRORNAS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEOLYSIS; PROTEOMICS; RNA PROCESSING, POST-TRANSCRIPTIONAL; STAUROSPORINE; SUBSTRATE SPECIFICITY; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84857129576     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1117158109     Document Type: Article

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