-
1
-
-
0026598246
-
Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium
-
Abou-Samra AB, Jüppner H, Force T, Freeman MW, Kong XF, Schipani E, Urena P, Richards J, Bonventre JV, and Potts JT, Jr, et al. (1992) Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89:2732-2736.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2732-2736
-
-
Abou-Samra, A.B.1
Jüppner, H.2
Force, T.3
Freeman, M.W.4
Kong, X.F.5
Schipani, E.6
Urena, P.7
Richards, J.8
Bonventre, J.V.9
Potts Jr., J.T.10
-
2
-
-
84867290208
-
Measurements of b-arrestin recruitment to activated seven transmembrane receptors using enzyme complementation
-
Bassoni DL, Raab WJ, Achacoso PL, Loh CY, and Wehrman TS (2012) Measurements of b-arrestin recruitment to activated seven transmembrane receptors using enzyme complementation. Methods Mol Biol 897:181-203.
-
(2012)
Methods Mol Biol
, vol.897
, pp. 181-203
-
-
Bassoni, D.L.1
Raab, W.J.2
Achacoso, P.L.3
Loh, C.Y.4
Wehrman, T.S.5
-
3
-
-
0037064132
-
Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations
-
Bisello A, Chorev M, Rosenblatt M, Monticelli L, Mierke DF, and Ferrari SL (2002) Selective ligand-induced stabilization of active and desensitized parathyroid hormone type 1 receptor conformations. J Biol Chem 277:38524-38530.
-
(2002)
J Biol Chem
, vol.277
, pp. 38524-38530
-
-
Bisello, A.1
Chorev, M.2
Rosenblatt, M.3
Monticelli, L.4
Mierke, D.F.5
Ferrari, S.L.6
-
4
-
-
67349122041
-
Structure-function relationship studies of PTH(1-11) analogues containing Damino acids
-
Caporale A, Biondi B, Schievano E, Wittelsberger A, Mammi S, and Peggion E (2009) Structure-function relationship studies of PTH(1-11) analogues containing Damino acids. Eur J Pharmacol 611:1-7.
-
(2009)
Eur J Pharmacol
, vol.611
, pp. 1-7
-
-
Caporale, A.1
Biondi, B.2
Schievano, E.3
Wittelsberger, A.4
Mammi, S.5
Peggion, E.6
-
5
-
-
78449304780
-
Synthesis and structural studies of new analogues of PTH(1-11) containing Ca-tetra-substituted amino acids in position 8
-
Caporale A, Sturlese M, Schievano E, Mammi S, and Peggion E (2010) Synthesis and structural studies of new analogues of PTH(1-11) containing Ca-tetra-substituted amino acids in position 8. Amino Acids 39:1369-1379.
-
(2010)
Amino Acids
, vol.39
, pp. 1369-1379
-
-
Caporale, A.1
Sturlese, M.2
Schievano, E.3
Mammi, S.4
Peggion, E.5
-
6
-
-
27644521278
-
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism
-
Castro M, Nikolaev VO, Palm D, Lohse MJ, and Vilardaga JP (2005) Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. Proc Natl Acad Sci USA 102:16084-16089.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16084-16089
-
-
Castro, M.1
Nikolaev, V.O.2
Palm, D.3
Lohse, M.J.4
Vilardaga, J.P.5
-
7
-
-
0027716654
-
Anabolic actions of parathyroid hormone on bone
-
Dempster DW, Cosman F, Parisien M, Shen V, and Lindsay R (1993) Anabolic actions of parathyroid hormone on bone. Endocr Rev 14:690-709.
-
(1993)
Endocr Rev
, vol.14
, pp. 690-709
-
-
Dempster, D.W.1
Cosman, F.2
Parisien, M.3
Shen, V.4
Lindsay, R.5
-
8
-
-
15444367508
-
Bone response to intermittent parathyroid hormone is altered in mice null for beta-Arrestin2
-
Ferrari SL, Pierroz DD, Glatt V, Goddard DS, Bianchi EN, Lin FT, Manen D, and Bouxsein ML (2005) Bone response to intermittent parathyroid hormone is altered in mice null for beta-Arrestin2. Endocrinology 146:1854-1862.
-
(2005)
Endocrinology
, vol.146
, pp. 1854-1862
-
-
Ferrari, S.L.1
Pierroz, D.D.2
Glatt, V.3
Goddard, D.S.4
Bianchi, E.N.5
Lin, F.T.6
Manen, D.7
Bouxsein, M.L.8
-
9
-
-
0001163236
-
-
(Bilezikian JP, Raisz LG, and Rodan GA, eds, ed), Academic Press, Inc., San Diego, CA
-
Fitzpatrick LA and Bilezikian JP (1996) Principles of Bone Biology (Bilezikian JP, Raisz LG, and Rodan GA, eds, ed) pp 339-346, Academic Press, Inc., San Diego, CA.
-
(1996)
Principles of Bone Biology
, pp. 339-346
-
-
Fitzpatrick, L.A.1
Bilezikian, J.P.2
-
10
-
-
0035405802
-
Molecular properties of the PTH/PTHrP receptor
-
Gardella TJ and Jüppner H (2001) Molecular properties of the PTH/PTHrP receptor. Trends Endocrinol Metab 12:210-217.
-
(2001)
Trends Endocrinol Metab
, vol.12
, pp. 210-217
-
-
Gardella, T.J.1
Jüppner, H.2
-
11
-
-
13444274543
-
Parathyroid hormone and parathyroid hormone-related peptide, and their receptors
-
Gensure RC, Gardella TJ, and Jüppner H (2005) Parathyroid hormone and parathyroid hormone-related peptide, and their receptors. Biochem Biophys Res Commun 328:666-678.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 666-678
-
-
Gensure, R.C.1
Gardella, T.J.2
Jüppner, H.3
-
12
-
-
33744957160
-
Distinct beta-arrestin-and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
-
Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, Wang S, Eckhardt AE, Cowan CL, Spurney RF, and Luttrell LM, et al. (2006) Distinct beta-arrestin-and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J Biol Chem 281:10856-10864.
-
(2006)
J Biol Chem
, vol.281
, pp. 10856-10864
-
-
Gesty-Palmer, D.1
Chen, M.2
Reiter, E.3
Ahn, S.4
Nelson, C.D.5
Wang, S.6
Eckhardt, A.E.7
Cowan, C.L.8
Spurney, R.F.9
Luttrell, L.M.10
-
13
-
-
73949084919
-
A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation
-
Gesty-Palmer D, Flannery P, Yuan L, Corsino L, Spurney R, Lefkowitz RJ, and Lutrell LM (2009) A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med 1:1-20.
-
(2009)
Sci Transl Med
, vol.1
, pp. 1-20
-
-
Gesty-Palmer, D.1
Flannery, P.2
Yuan, L.3
Corsino, L.4
Spurney, R.5
Lefkowitz, R.J.6
Lutrell, L.M.7
-
14
-
-
77954923592
-
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology 15
-
Guo J, Liu M, Yang D, Bouxsein ML, Thomas CC, Schipani E, Bringhurst FR, and Kronenberg HM (2010) Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology 15. Endocrinology 151:3502-3513.
-
(2010)
Endocrinology
, vol.151
, pp. 3502-3513
-
-
Guo, J.1
Liu, M.2
Yang, D.3
Bouxsein, M.L.4
Thomas, C.C.5
Schipani, E.6
Bringhurst, F.R.7
Kronenberg, H.M.8
-
15
-
-
0029855956
-
Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo
-
Hilliker S, Wergedal JE, Gruber HE, Bettica P, and Baylink DJ (1996) Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo. Bone 19: 469-477.
-
(1996)
Bone
, vol.19
, pp. 469-477
-
-
Hilliker, S.1
Wergedal, J.E.2
Gruber, H.E.3
Bettica, P.4
Baylink, D.J.5
-
16
-
-
0026584625
-
Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
-
Hock JM and Gera I (1992) Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone. J Bone Miner Res 7:65-72.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 65-72
-
-
Hock, J.M.1
Gera, I.2
-
17
-
-
34248577022
-
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
-
Jilka RL (2007) Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 40:1434-1446.
-
(2007)
Bone
, vol.40
, pp. 1434-1446
-
-
Jilka, R.L.1
-
19
-
-
36348946976
-
Functional selectivity through protean and biased agonism: Who steers the ship?
-
Kenakin T (2007) Functional selectivity through protean and biased agonism: Who steers the ship? Mol Pharmacol 72:1393-1401.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1393-1401
-
-
Kenakin, T.1
-
20
-
-
78751498756
-
Functional selectivity and biased receptor signaling
-
Kenakin T (2011) Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 336:296-302.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 296-302
-
-
Kenakin, T.1
-
21
-
-
0034878897
-
Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation
-
Ma YL, Cain RL, Halladay DL, Yang X, Zeng Q, Miles RR, Chandrasekhar S, Martin TJ, and Onyia JE (2001) Catabolic effects of continuous human PTH (1-38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation. Endocrinology 142:4047-4054.
-
(2001)
Endocrinology
, vol.142
, pp. 4047-4054
-
-
Ma, Y.L.1
Cain, R.L.2
Halladay, D.L.3
Yang, X.4
Zeng, Q.5
Miles, R.R.6
Chandrasekhar, S.7
Martin, T.J.8
Onyia, J.E.9
-
22
-
-
58849083281
-
Characterizing cannabinoid CB2 receptor ligands using DiscoveRx Path-Hunter beta-arrestin assay
-
McGuinness D, Malikzay A, Visconti R, Lin K, Bayne M, Monsma F, and Lunn CA (2009) Characterizing cannabinoid CB2 receptor ligands using DiscoveRx Path-Hunter beta-arrestin assay. J Biomol Screen 14:49-58.
-
(2009)
J Biomol Screen
, vol.14
, pp. 49-58
-
-
McGuinness, D.1
Malikzay, A.2
Visconti, R.3
Lin, K.4
Bayne, M.5
Monsma, F.6
Lunn, C.A.7
-
23
-
-
13944269143
-
In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity
-
Murrills RJ, Matteo JJ, Samuel RL, Andrews JL, Bhat BM, Coleburn VE, Kharode YP, and Bex FJ (2004) In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity. Bone 35:1263-1272.
-
(2004)
Bone
, vol.35
, pp. 1263-1272
-
-
Murrills, R.J.1
Matteo, J.J.2
Samuel, R.L.3
Andrews, J.L.4
Bhat, B.M.5
Coleburn, V.E.6
Kharode, Y.P.7
Bex, F.J.8
-
24
-
-
79955916568
-
ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats
-
Neerup TS, Stahlhut M, Petersen JS, Daugaard JR, Jensen JE, Peng Z, Morko J, and Thorkildsen C (2011) ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats. Bone 48:1319-1327.
-
(2011)
Bone
, vol.48
, pp. 1319-1327
-
-
Neerup, T.S.1
Stahlhut, M.2
Petersen, J.S.3
Daugaard, J.R.4
Jensen, J.E.5
Peng, Z.6
Morko, J.7
Thorkildsen, C.8
-
25
-
-
79960902373
-
Understanding the effect of different assay formats on agonist parameters: A study using the m-opioid receptor
-
Nickolls SA, Waterfield A, Williams RE, and Kinloch RA (2011) Understanding the effect of different assay formats on agonist parameters: A study using the m-opioid receptor. J Biomol Screen 16:706-716.
-
(2011)
J Biomol Screen
, vol.16
, pp. 706-716
-
-
Nickolls, S.A.1
Waterfield, A.2
Williams, R.E.3
Kinloch, R.A.4
-
26
-
-
79953859677
-
G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone
-
Ogata N, Shinoda Y, Wettschureck N, Offermanns S, Takeda S, Nakamura K, Segre GV, Chung UI, and Kawaguchi H (2011) G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone. J Biol Chem 286: 13733-13740.
-
(2011)
J Biol Chem
, vol.286
, pp. 13733-13740
-
-
Ogata, N.1
Shinoda, Y.2
Wettschureck, N.3
Offermanns, S.4
Takeda, S.5
Nakamura, K.6
Segre, G.V.7
Chung, U.I.8
Kawaguchi, H.9
-
27
-
-
55949089800
-
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation
-
Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT, Jr, and Gardella TJ (2008) Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci USA 105:16525-16530.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16525-16530
-
-
Okazaki, M.1
Ferrandon, S.2
Vilardaga, J.P.3
Bouxsein, M.L.4
Potts Jr., J.T.5
Gardella, T.J.6
-
28
-
-
34147207553
-
Beta galactosidase complementation: A cell-based luminescent assay platform for drug discovery
-
Olson KR and Eglen RM (2007) Beta galactosidase complementation: A cell-based luminescent assay platform for drug discovery. Assay Drug Dev Technol 5:137-144.
-
(2007)
Assay Drug Dev Technol
, vol.5
, pp. 137-144
-
-
Olson, K.R.1
Eglen, R.M.2
-
29
-
-
65949091145
-
Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice
-
Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, and BouxseinML, et al. (2009) Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. J Bone Miner Res 24:775-784.
-
(2009)
J Bone Miner Res
, vol.24
, pp. 775-784
-
-
Pierroz, D.D.1
Rufo, A.2
Bianchi, E.N.3
Glatt, V.4
Capulli, M.5
Rucci, N.6
Cavat, F.7
Rizzoli, R.8
Teti, A.9
Bouxsein, M.L.10
-
30
-
-
42449160533
-
Molecular recognition of parathyroid hormone by its G protein-coupled receptor
-
Pioszak AA and Xu HE (2008) Molecular recognition of parathyroid hormone by its G protein-coupled receptor. Proc Natl Acad Sci USA 105:5034-5039.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5034-5039
-
-
Pioszak, A.A.1
Xu, H.E.2
-
31
-
-
70350504319
-
Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides
-
Pioszak AA, Parker NR, Gardella TJ, and Xu HE (2009) Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides. J Biol Chem 284:28382-28391.
-
(2009)
J Biol Chem
, vol.284
, pp. 28382-28391
-
-
Pioszak, A.A.1
Parker, N.R.2
Gardella, T.J.3
Xu, H.E.4
-
32
-
-
80051979129
-
Quantifying ligand bias at seventransmembrane receptors
-
Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, and Lefkowitz RJ (2011) Quantifying ligand bias at seventransmembrane receptors. Mol Pharmacol 80:367-377.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 367-377
-
-
Rajagopal, S.1
Ahn, S.2
Rominger, D.H.3
Gowen-MacDonald, W.4
Lam, C.M.5
Dewire, S.M.6
Violin, J.D.7
Lefkowitz, R.J.8
-
33
-
-
84855901533
-
Molecular mechanism of b-arrestin-biased agonism at seven-transmembrane receptors
-
Reiter E, Ahn S, Shukla AK, and Lefkowitz RJ (2012) Molecular mechanism of b-arrestin-biased agonism at seven-transmembrane receptors. Annu Rev Pharmacol Toxicol 52:179-197.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 179-197
-
-
Reiter, E.1
Ahn, S.2
Shukla, A.K.3
Lefkowitz, R.J.4
-
34
-
-
33646254393
-
In vitro and in vivo effect of parathyroid hormone analogue (1-14 containing-amino-iso-butyric acid residue (Aib)13
-
Rhee Y, Lee W, Lee EJ, Ma S, Park SY, and Lim SK (2006) In vitro and in vivo effect of parathyroid hormone analogue (1-14) containing-amino-iso-butyric acid residue (Aib)1,3. Yonsei Med J 47:214-222.
-
(2006)
Yonsei Med J
, vol.47
, pp. 214-222
-
-
Rhee, Y.1
Lee, W.2
Lee, E.J.3
Ma, S.4
Park, S.Y.5
Lim, S.K.6
-
35
-
-
0027941168
-
Parathyroid hormone fragments may stimulate bone growth in ovariectomized rats by activating adenylyl cyclase
-
Rixon RH, Whitfield JF, Gagnon L, Isaacs RJ, Maclean S, Chakravarthy B, Durkin JP, Neugebauer W, Ross V, and Sung W, et al. (1994) Parathyroid hormone fragments may stimulate bone growth in ovariectomized rats by activating adenylyl cyclase. J Bone Miner Res 9:1179-1189.
-
(1994)
J Bone Miner Res
, vol.9
, pp. 1179-1189
-
-
Rixon, R.H.1
Whitfield, J.F.2
Gagnon, L.3
Isaacs, R.J.4
Maclean, S.5
Chakravarthy, B.6
Durkin, J.P.7
Neugebauer, W.8
Ross, V.9
Sung, W.10
-
36
-
-
0035966121
-
Parathyroid hormone (PTH)-(1-14) and-(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor
-
Shimizu N, Guo J, and Gardella TJ (2001) Parathyroid hormone (PTH)-(1-14) and-(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. J Biol Chem 276:49003-49012.
-
(2001)
J Biol Chem
, vol.276
, pp. 49003-49012
-
-
Shimizu, N.1
Guo, J.2
Gardella, T.J.3
-
37
-
-
12544259198
-
Amino-terminal parathyroid hormone fragment analogs containing alpha,alpha-di-alkyl amino acids at positions 1 and 3
-
Shimizu N, Dean T, Khatri A, and Gardella TJ (2004) Amino-terminal parathyroid hormone fragment analogs containing alpha,alpha-di-alkyl amino acids at positions 1 and 3. J Bone Miner Res 19:2078-2086.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 2078-2086
-
-
Shimizu, N.1
Dean, T.2
Khatri, A.3
Gardella, T.J.4
-
38
-
-
2542484525
-
Ligand-selective dissociation of activation and internalization of the parathyroid hormone (PTH) receptor: Conditional efficacy of PTH peptide fragments
-
Sneddon WB, Magyar CE, Willick GE, Syme CA, Galbiati F, Bisello A, and Friedman PA (2004) Ligand-selective dissociation of activation and internalization of the parathyroid hormone (PTH) receptor: Conditional efficacy of PTH peptide fragments. Endocrinology 145:2815-2823.
-
(2004)
Endocrinology
, vol.145
, pp. 2815-2823
-
-
Sneddon, W.B.1
Magyar, C.E.2
Willick, G.E.3
Syme, C.A.4
Galbiati, F.5
Bisello, A.6
Friedman, P.A.7
-
39
-
-
15744405759
-
Parathyroid hormone receptor trafficking contributes to the activation of extracellular signal-regulated kinases but is not required for regulation of cAMP signaling
-
Syme CA, Friedman PA, and Bisello A (2005) Parathyroid hormone receptor trafficking contributes to the activation of extracellular signal-regulated kinases but is not required for regulation of cAMP signaling. J Biol Chem 280:11281-11288.
-
(2005)
J Biol Chem
, vol.280
, pp. 11281-11288
-
-
Syme, C.A.1
Friedman, P.A.2
Bisello, A.3
-
40
-
-
0032918004
-
Dual signaling and ligand selectivity of the human PTH/PTHrP receptor
-
Takasu H, Guo J, and Bringhurst FR (1999) Dual signaling and ligand selectivity of the human PTH/PTHrP receptor. J Bone Miner Res 14:11-20.
-
(1999)
J Bone Miner Res
, vol.14
, pp. 11-20
-
-
Takasu, H.1
Guo, J.2
Bringhurst, F.R.3
-
41
-
-
0020064261
-
Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: Differential effects of intermittent and continuous administration
-
Tam CS, Heersche JN, Murray TM, and Parsons JA (1982) Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: Differential effects of intermittent and continuous administration. Endocrinology 110: 506-512.
-
(1982)
Endocrinology
, vol.110
, pp. 506-512
-
-
Tam, C.S.1
Heersche, J.N.2
Murray, T.M.3
Parsons, J.A.4
-
42
-
-
84856269291
-
From parathyroid hormone to cytosolic Ca21 signals
-
Taylor CW and Tovey SC (2012) From parathyroid hormone to cytosolic Ca21 signals. Biochem Soc Trans 40:147-152.
-
(2012)
Biochem Soc Trans
, vol.40
, pp. 147-152
-
-
Taylor, C.W.1
Tovey, S.C.2
-
43
-
-
80053287704
-
Monitoring Gq-coupled receptor response through inositol phosphate quantification with the IP-One assay
-
Trinquet E, Bouhelal R, and Dietz M (2011) Monitoring Gq-coupled receptor response through inositol phosphate quantification with the IP-One assay. Expert Opin Drug Discov 6:981-994.
-
(2011)
Expert Opin Drug Discov
, vol.6
, pp. 981-994
-
-
Trinquet, E.1
Bouhelal, R.2
Dietz, M.3
-
44
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, and Sexton PM, et al. (2007) Functional selectivity and classical concepts of quantitative pharmacology. J Pharmacol Exp Ther 320: 1-13.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 1-13
-
-
Urban, J.D.1
Clarke, W.P.2
Von Zastrow, M.3
Nichols, D.E.4
Kobilka, B.5
Weinstein, H.6
Javitch, J.A.7
Roth, B.L.8
Christopoulos, A.9
Sexton, P.M.10
-
45
-
-
84875109836
-
B-Arrestin-biased signaling of PTH analogs of the type 1 parathyroid hormone receptor
-
van der Lee MM, Verkaar F, Wat JW, van Offenbeek J, Timmerman M, Voorneveld L, van Lith LH, and Zaman GJ (2013) b-Arrestin-biased signaling of PTH analogs of the type 1 parathyroid hormone receptor. Cell Signal 25:527-538.
-
(2013)
Cell Signal
, vol.25
, pp. 527-538
-
-
Van Der Lee, M.M.1
Verkaar, F.2
Wat, J.W.3
Van Offenbeek, J.4
Timmerman, M.5
Voorneveld, L.6
Van Lith, L.H.7
Zaman, G.J.8
-
46
-
-
78650968168
-
Molecular basis of parathyroid hormone receptor signaling and trafficking: A family B GPCR paradigm
-
Vilardaga JP, Romero G, Friedman PA, and Gardella TJ (2011) Molecular basis of parathyroid hormone receptor signaling and trafficking: A family B GPCR paradigm. Cell Mol Life Sci 68:1-13.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 1-13
-
-
Vilardaga, J.P.1
Romero, G.2
Friedman, P.A.3
Gardella, T.J.4
-
47
-
-
78649803293
-
Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Ga(12) or constitutively active RhoA
-
Wang J and Stern PH (2010) Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Ga(12) or constitutively active RhoA. J Cell Biochem 111:1531-1536.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1531-1536
-
-
Wang, J.1
Stern, P.H.2
-
48
-
-
0030031878
-
Stimulation of the growth of femoral trabecular bone in ovariectomized rats by the novel parathyroid hormone fragment, hPTH-(1-31) NH2 (Ostabolin
-
Whitfield JF, Morley P, Willick GE, Ross V, Barbier JR, Isaacs RJ, and Ohannessian-Barry L (1996) Stimulation of the growth of femoral trabecular bone in ovariectomized rats by the novel parathyroid hormone fragment, hPTH-(1-31)NH2 (Ostabolin). Calcif Tissue Int 58:81-87.
-
(1996)
Calcif Tissue Int
, vol.58
, pp. 81-87
-
-
Whitfield, J.F.1
Morley, P.2
Willick, G.E.3
Ross, V.4
Barbier, J.R.5
Isaacs, R.J.6
Ohannessian-Barry, L.7
-
49
-
-
34249075203
-
Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone
-
Yang D, Singh R, Divieti P, Guo J, Bouxsein ML, and Bringhurst FR (2007) Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone. Bone 40: 1453-1461.
-
(2007)
Bone
, vol.40
, pp. 1453-1461
-
-
Yang, D.1
Singh, R.2
Divieti, P.3
Guo, J.4
Bouxsein, M.L.5
Bringhurst, F.R.6
-
50
-
-
66449121455
-
Lipid G protein-coupled receptor ligand identification using betaarrestin PathHunter assay
-
Yin H, Chu A, Li W, Wang B, Shelton F, Otero F, Nguyen DG, Caldwell JS, and Chen YA (2009) Lipid G protein-coupled receptor ligand identification using betaarrestin PathHunter assay. J Biol Chem 284:12328-12338.
-
(2009)
J Biol Chem
, vol.284
, pp. 12328-12338
-
-
Yin, H.1
Chu, A.2
Li, W.3
Wang, B.4
Shelton, F.5
Otero, F.6
Nguyen, D.G.7
Caldwell, J.S.8
Chen, Y.A.9
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