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Volumn 48, Issue 6, 2011, Pages 1319-1327

ZP2307, a novel, cyclic PTH(1-17) analog that augments bone mass in ovariectomized rats

Author keywords

Histomorphometry; Ionized free serum calcium; Osteoporosis; OVX; Parathyroid hormone analog

Indexed keywords

CALCIUM; PARATHYROID HORMONE DERIVATIVE; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE[1-34]; UNCLASSIFIED DRUG; ZP 2307;

EID: 79955916568     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.02.019     Document Type: Article
Times cited : (12)

References (35)
  • 1
    • 33646889773 scopus 로고    scopus 로고
    • Bone quality-the material and structural basis of bone strength and fragility
    • Seeman E., Delmas P.D. Bone quality-the material and structural basis of bone strength and fragility. N. Engl. J. Med. 2006, 354:2250-2261.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2250-2261
    • Seeman, E.1    Delmas, P.D.2
  • 3
    • 0028838352 scopus 로고
    • Osteoporosis: diagnosis and management today and tomorrow
    • Christiansen C. Osteoporosis: diagnosis and management today and tomorrow. Bone 1995, 17:513S-516S.
    • (1995) Bone , vol.17
    • Christiansen, C.1
  • 7
    • 0026039728 scopus 로고
    • Preexisting bone loss associated with ovariectomy in rats is reversed by parathyroid hormone
    • Liu C.C., Kalu D.N., Salerno E., Echon R., Hollis B.W., Ray M. Preexisting bone loss associated with ovariectomy in rats is reversed by parathyroid hormone. J. Bone Miner. Res. 1991, 6:1071-1080.
    • (1991) J. Bone Miner. Res. , vol.6 , pp. 1071-1080
    • Liu, C.C.1    Kalu, D.N.2    Salerno, E.3    Echon, R.4    Hollis, B.W.5    Ray, M.6
  • 8
    • 0034115133 scopus 로고    scopus 로고
    • Bone anabolic effects of PTH(1-34) and salmon calcitonin in ovariectomy- and ovariectomy-steroid-induced osteopenic rats: a histomorphometric and biomechanical study
    • Fukushima T., Nitta T., Furuichi H., Izumo N., Fukuyama T., Nakamuta H., Koida M. Bone anabolic effects of PTH(1-34) and salmon calcitonin in ovariectomy- and ovariectomy-steroid-induced osteopenic rats: a histomorphometric and biomechanical study. Jpn J. Pharmacol. 2000, 82:240-246.
    • (2000) Jpn J. Pharmacol. , vol.82 , pp. 240-246
    • Fukushima, T.1    Nitta, T.2    Furuichi, H.3    Izumo, N.4    Fukuyama, T.5    Nakamuta, H.6    Koida, M.7
  • 10
    • 3042535449 scopus 로고    scopus 로고
    • What's new with PTH in osteoporosis: where are we and where are we headed?
    • Rosen C.J. What's new with PTH in osteoporosis: where are we and where are we headed?. Trends Endocrinol. Metab. 2004, 15:229-233.
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 229-233
    • Rosen, C.J.1
  • 13
    • 13944269143 scopus 로고    scopus 로고
    • In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity
    • Murrills R.J., Matteo J.J., Samuel R.L., Andrews J.L., Bhat B.M., Coleburn V.E., Kharode Y.P., Bex F.J. In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity. Bone 2004, 35:1263-1272.
    • (2004) Bone , vol.35 , pp. 1263-1272
    • Murrills, R.J.1    Matteo, J.J.2    Samuel, R.L.3    Andrews, J.L.4    Bhat, B.M.5    Coleburn, V.E.6    Kharode, Y.P.7    Bex, F.J.8
  • 14
    • 33646254393 scopus 로고    scopus 로고
    • In vitro and in vivo effect of parathyroid hormone analogue (1-14) containing -amino-iso-butyric acid residue (Aib)1,3
    • Rhee Y., Lee W., Lee E.J., Ma S., Park S.Y., Lim S.K. In vitro and in vivo effect of parathyroid hormone analogue (1-14) containing -amino-iso-butyric acid residue (Aib)1,3. Yonsei Med. J. 2006, 47:214-222.
    • (2006) Yonsei Med. J. , vol.47 , pp. 214-222
    • Rhee, Y.1    Lee, W.2    Lee, E.J.3    Ma, S.4    Park, S.Y.5    Lim, S.K.6
  • 15
    • 42749095019 scopus 로고    scopus 로고
    • Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone
    • Goltzman D. Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone. Arch. Biochem. Biophys. 2008, 473:218-224.
    • (2008) Arch. Biochem. Biophys. , vol.473 , pp. 218-224
    • Goltzman, D.1
  • 17
    • 0033304631 scopus 로고    scopus 로고
    • The (1-14) fragment of parathyroid hormone (PTH) activates intact and amino-terminally truncated PTH-1 receptors
    • Luck M.D., Carter P.H., Gardella T.J. The (1-14) fragment of parathyroid hormone (PTH) activates intact and amino-terminally truncated PTH-1 receptors. Mol. Endocrinol. 1999, 13:670-680.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 670-680
    • Luck, M.D.1    Carter, P.H.2    Gardella, T.J.3
  • 18
    • 12544259198 scopus 로고    scopus 로고
    • Amino-terminal parathyroid hormone fragment analogs containing alpha, alpha-di-alkyl amino acids at positions 1 and 3
    • Shimizu N., Dean T., Khatri A., Gardella T.J. Amino-terminal parathyroid hormone fragment analogs containing alpha, alpha-di-alkyl amino acids at positions 1 and 3. J. Bone Miner. Res. 2004, 19:2078-2086.
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 2078-2086
    • Shimizu, N.1    Dean, T.2    Khatri, A.3    Gardella, T.J.4
  • 19
    • 0034698165 scopus 로고    scopus 로고
    • Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor
    • Shimizu M., Potts J.T., Gardella T.J. Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor. J. Biol. Chem. 2000, 275:21836-21843.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21836-21843
    • Shimizu, M.1    Potts, J.T.2    Gardella, T.J.3
  • 20
    • 0035966121 scopus 로고    scopus 로고
    • Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor
    • Shimizu N., Guo J., Gardella T.J. Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor. J. Biol. Chem. 2001, 276:49003-49012.
    • (2001) J. Biol. Chem. , vol.276 , pp. 49003-49012
    • Shimizu, N.1    Guo, J.2    Gardella, T.J.3
  • 22
    • 0030740994 scopus 로고    scopus 로고
    • Cyclization by a specific lactam increases the ability of human parathyroid hormone (hPTH)-(1-31)NH2 to stimulate bone growth in ovariectomized rats
    • Whitfield J.F., Morley P., Willick G., Langille R., Ross V., MacLean S., Barbier J.R. Cyclization by a specific lactam increases the ability of human parathyroid hormone (hPTH)-(1-31)NH2 to stimulate bone growth in ovariectomized rats. J. Bone Miner. Res. 1997, 12:1246-1252.
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 1246-1252
    • Whitfield, J.F.1    Morley, P.2    Willick, G.3    Langille, R.4    Ross, V.5    MacLean, S.6    Barbier, J.R.7
  • 23
    • 0031698033 scopus 로고    scopus 로고
    • Comparison of the abilities of human parathyroid hormone (hPTH)-(1-34) and [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats
    • Whitfield J.F., Morley P., Willick G., MacLean S., Ross V., Isaacs R.J., Barbier J.R. Comparison of the abilities of human parathyroid hormone (hPTH)-(1-34) and [Leu27]-cyclo(Glu22-Lys26)-hPTH-(1-31)NH2 to stimulate femoral trabecular bone growth in ovariectomized rats. Calcif. Tissue Int. 1998, 63:423-428.
    • (1998) Calcif. Tissue Int. , vol.63 , pp. 423-428
    • Whitfield, J.F.1    Morley, P.2    Willick, G.3    MacLean, S.4    Ross, V.5    Isaacs, R.J.6    Barbier, J.R.7
  • 24
  • 26
    • 0042333459 scopus 로고    scopus 로고
    • Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure
    • Frolik C.A., Black E.C., Cain R.L., Satterwhite J.H., Brown-Augsburger P.L., Sato M., Hock J.M. Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure. Bone 2003, 33:372-379.
    • (2003) Bone , vol.33 , pp. 372-379
    • Frolik, C.A.1    Black, E.C.2    Cain, R.L.3    Satterwhite, J.H.4    Brown-Augsburger, P.L.5    Sato, M.6    Hock, J.M.7
  • 27
    • 0030987016 scopus 로고    scopus 로고
    • Mono- and bicyclic analogs of parathyroid hormone-related protein. 1. Synthesis and biological studies
    • Bisello A., Nakamoto C., Rosenblatt M., Chorev M. Mono- and bicyclic analogs of parathyroid hormone-related protein. 1. Synthesis and biological studies. Biochemistry 1997, 36:3293-3299.
    • (1997) Biochemistry , vol.36 , pp. 3293-3299
    • Bisello, A.1    Nakamoto, C.2    Rosenblatt, M.3    Chorev, M.4
  • 28
    • 58649123545 scopus 로고    scopus 로고
    • Prolonged treatments with anti-resorptive agents and PTH have different effects on bone strength and the degree of mineralization in old estrogen deficient osteoporotic rats
    • Cheng Z., Yao W., Zimmermann E.A., Busse C., Ritchie R.O., Lane N.E. Prolonged treatments with anti-resorptive agents and PTH have different effects on bone strength and the degree of mineralization in old estrogen deficient osteoporotic rats. J. Bone Miner. Res. 2009, 1-43.
    • (2009) J. Bone Miner. Res. , pp. 1-43
    • Cheng, Z.1    Yao, W.2    Zimmermann, E.A.3    Busse, C.4    Ritchie, R.O.5    Lane, N.E.6
  • 29
    • 0141785434 scopus 로고    scopus 로고
    • Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture
    • Lane N.E., Yao W., Kinney J.H., Modin G., Balooch M., Wronski T.J. Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture. J. Bone Miner. Res. 2003, 18:2105-2115.
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 2105-2115
    • Lane, N.E.1    Yao, W.2    Kinney, J.H.3    Modin, G.4    Balooch, M.5    Wronski, T.J.6
  • 30
    • 0032908602 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates cancellous bone formation at skeletal sites regardless of marrow composition in ovariectomized rats
    • Li M., Liang H., Shen Y., Wronski T.J. Parathyroid hormone stimulates cancellous bone formation at skeletal sites regardless of marrow composition in ovariectomized rats. Bone 1999, 24:95-100.
    • (1999) Bone , vol.24 , pp. 95-100
    • Li, M.1    Liang, H.2    Shen, Y.3    Wronski, T.J.4
  • 31
    • 29044446044 scopus 로고    scopus 로고
    • Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats
    • Yao W., Hadi T., Jiang Y., Lotz J., Wronski T.J., Lane N.E. Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats. Osteoporos. Int. 2005, 16:1939-1947.
    • (2005) Osteoporos. Int. , vol.16 , pp. 1939-1947
    • Yao, W.1    Hadi, T.2    Jiang, Y.3    Lotz, J.4    Wronski, T.J.5    Lane, N.E.6
  • 32
    • 0033916327 scopus 로고    scopus 로고
    • Six-month daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: a comparison of human parathyroid hormone 1-34, parathyroid hormone-related protein 1-36, and SDZ-parathyroid hormone 893
    • Stewart A.F., Cain R.L., Burr D.B., Jacob D., Turner C.H., Hock J.M. Six-month daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: a comparison of human parathyroid hormone 1-34, parathyroid hormone-related protein 1-36, and SDZ-parathyroid hormone 893. J. Bone Miner. Res. 2000, 15:1517-1525.
    • (2000) J. Bone Miner. Res. , vol.15 , pp. 1517-1525
    • Stewart, A.F.1    Cain, R.L.2    Burr, D.B.3    Jacob, D.4    Turner, C.H.5    Hock, J.M.6
  • 33
    • 33846932327 scopus 로고    scopus 로고
    • A comparative study of the bone-restorative efficacy of anabolic agents in aged ovariectomized rats
    • Iwaniec U.T., Moore K., Rivera M.F., Myers S.E., Vanegas S.M., Wronski T.J. A comparative study of the bone-restorative efficacy of anabolic agents in aged ovariectomized rats. Osteoporos. Int. 2007, 18:351-362.
    • (2007) Osteoporos. Int. , vol.18 , pp. 351-362
    • Iwaniec, U.T.1    Moore, K.2    Rivera, M.F.3    Myers, S.E.4    Vanegas, S.M.5    Wronski, T.J.6
  • 34
    • 23844555574 scopus 로고    scopus 로고
    • Raloxifene and teriparatide (hPTH 1-34) have complementary effects on the osteopenic skeleton of ovariectomized rats
    • Ma Y.L., Bryant H.U., Zeng Q., Schmidt A., Jee W.S., Sato M. Raloxifene and teriparatide (hPTH 1-34) have complementary effects on the osteopenic skeleton of ovariectomized rats. J. Bone Miner. Metab. 2005, 23(Suppl):62-68.
    • (2005) J. Bone Miner. Metab. , vol.23 , Issue.SUPPL. , pp. 62-68
    • Ma, Y.L.1    Bryant, H.U.2    Zeng, Q.3    Schmidt, A.4    Jee, W.S.5    Sato, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.