In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity

Bone

Volumn 35, Issue 6, 2004, Pages 1263-1272

  Murrills, Richard J ^a   Matteo, Jeanne J ^a   Samuel, Rachelle L ^a   Andrews, Jennifer L ^a   Bhat, Bheem M ^a   Coleburn, Valerie E ^a   Kharode, Yogendra P ^a   Bex, Frederick J ^a  

^a PFIZER INC   (United States)

Author keywords

Bone mineral density; CRE; G protein signaling; Osteoblasts; PTH PTHrP

Indexed keywords

CALCITONIN; CYCLIC AMP; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; ISOPRENALINE; MODIFIED PARATHYROID HORMONE[1-21]; N PROPIONYLPARATHYROID HORMONE[2-34]; PARATHYROID HORMONE DERIVATIVE; PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE RELATED PROTEIN[1-16]; PARATHYROID HORMONE RELATED PROTEIN[1-34]; PARATHYROID HORMONE RELATED PROTEIN[7-34]; PARATHYROID HORMONE[1-27]; PARATHYROID HORMONE[1-28]; PARATHYROID HORMONE[1-29]; PARATHYROID HORMONE[1-30]; PARATHYROID HORMONE[1-31]; PARATHYROID HORMONE[1-34]; PARATHYROID HORMONE[2-34]; PARATHYROID HORMONE[2-38]; PARATHYROID HORMONE[28-48]; PARATHYROID HORMONE[3-34]; PROSTAGLANDIN E2; RS 25638; RS 66271; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

ARTICLE; BONE DEVELOPMENT; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; GENETIC TRANSFECTION; HORMONE ACTION; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN BINDING; RAT; RECEPTOR BINDING;

EID: 13944269143     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.08.015     Document Type: Article

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