Combination of tramadol with minocycline exerted synergistic effects on a rat model of nerve injury-induced neuropathic pain

NeuroSignals

Volumn 21, Issue 3-4, 2013, Pages 184-196

  Mei, Xiao Peng ^a   Chen, Lei ^a   Wang, Wei ^a   Wu, Dan ^a   Wang, Li Ying ^a   Zhang, Ting ^a   Zhang, Hui ^a   Xu, Li Xian ^a   Li, Yun Qing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Analgesic; Antiallodynia; Microglia; Spinal cord; Spinal nerve ligation

Indexed keywords

MEMBRANE PROTEIN; MINOCYCLINE; OX 42 PROTEIN; PROTEIN FOS; TRAMADOL; UNCLASSIFIED DRUG; OX42 PROTEIN; PROTEIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR PARAMETERS; CONTROLLED STUDY; DOWN REGULATION; GLIAL ACTIVATION; HUMAN; HYPOTHESIS; IMMUNOFLUORESCENCE; MALE; NERVE CELL ACTIVATION; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PERIPHERAL NERVE INJURY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; ROTAROD TEST; SPINAL CORD DORSAL HORN; SPINAL NERVE; TREATMENT OUTCOME; ANALGESIA; ANIMAL BEHAVIOR; ANIMAL TISSUE; COMPARATIVE EFFECTIVENESS; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENTIATION; GLIA; LOCOMOTION; MONOTHERAPY; MOTOR PERFORMANCE; NERVE CELL; NEUROMODULATION; SPINAL NERVE LIGATION INJURY; TREATMENT RESPONSE;

ANALGESICS, OPIOID; ANIMALS; ANTI-BACTERIAL AGENTS; ASTROCYTES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HYPERALGESIA; MALE; MICROGLIA; MINOCYCLINE; NEURALGIA; PAIN MEASUREMENT; PERIPHERAL NERVE INJURIES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; ROTAROD PERFORMANCE TEST; SPINAL CORD; TRAMADOL;

EID: 84878018918     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000338049     Document Type: Article

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