Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 311, Issue 2, 2004, Pages 576-584

  Iyengar, Smriti ^a   Webster, Amy A ^a   Hemrick Luecke, Susan K ^a   Xu, Jimmy Yu ^a   Simmons, Rosa Maria A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA METHYL META TYROSINE; CHLORAMPHETAMINE; DESIPRAMINE; DULOXETINE; FORMALDEHYDE; GABAPENTIN; META TYROSINE; MILNACIPRAN; NISOXETINE; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; THIONISOXETINE; UNCLASSIFIED DRUG; VENLAFAXINE;

ALLODYNIA; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE MODEL; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; INHIBITION KINETICS; LIGATION; MALE; NEUROLOGIC DISEASE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; NORADRENALIN RELEASE; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SPINAL NERVE; TAIL FLICK TEST;

ACUTE DISEASE; AMINES; AMITRIPTYLINE; ANIMALS; CONSCIOUS SEDATION; CYCLOHEXANECARBOXYLIC ACIDS; CYCLOHEXANOLS; CYCLOPROPANES; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FLUOXETINE; FORMALDEHYDE; GAMMA-AMINOBUTYRIC ACID; MALE; METHYLTYROSINES; NEUROMUSCULAR JUNCTION; NOREPINEPHRINE; P-CHLOROAMPHETAMINE; PAIN; PAROXETINE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; THIOPHENES;

EID: 6244309292     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.070656     Document Type: Article

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