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Volumn 25, Issue 7, 2011, Pages 1355-1366

Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain

Author keywords

Astrocyte; C jun n terminal kinase; Neuropathic pain; NMDA receptor; Spinal cord

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; 7 NITROINDAZOLE; DIZOCILPINE; IFENPRODIL; INTERLEUKIN 1BETA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NEURONAL NITRIC OXIDE SYNTHASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 80052730373     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2011.04.002     Document Type: Article
Times cited : (53)

References (40)
  • 3
    • 77951915235 scopus 로고    scopus 로고
    • Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition
    • Bessero A.C., Chiodini F., Rungger-Brandle E., Bonny C., Clarke P.G. Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition. J. Neurochem. 2010, 113:1307-1318.
    • (2010) J. Neurochem. , vol.113 , pp. 1307-1318
    • Bessero, A.C.1    Chiodini, F.2    Rungger-Brandle, E.3    Bonny, C.4    Clarke, P.G.5
  • 5
    • 33646947850 scopus 로고    scopus 로고
    • Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide
    • Brahmachari S., Fung Y.K., Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J. Neurosci. 2006, 26:4930-4939.
    • (2006) J. Neurosci. , vol.26 , pp. 4930-4939
    • Brahmachari, S.1    Fung, Y.K.2    Pahan, K.3
  • 6
    • 1642421156 scopus 로고    scopus 로고
    • The role of the N-methyl-d-aspartate receptor NR1 subunit in peripheral nerve injury-induced mechanical allodynia, glial activation and chemokine expression in the mouse
    • Bursztajn S., Rutkowski M.D., Deleo J.A. The role of the N-methyl-d-aspartate receptor NR1 subunit in peripheral nerve injury-induced mechanical allodynia, glial activation and chemokine expression in the mouse. Neuroscience 2004, 125:269-275.
    • (2004) Neuroscience , vol.125 , pp. 269-275
    • Bursztajn, S.1    Rutkowski, M.D.2    Deleo, J.A.3
  • 8
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: a maladaptive response of the nervous system to damage
    • Costigan M., Scholz J., Woolf C.J. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu. Rev. Neurosci. 2009, 32:1-32.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 9
    • 33644946435 scopus 로고    scopus 로고
    • Localization of soluble guanylyl cyclase in the superficial dorsal horn
    • Ding J.D., Weinberg R.J. Localization of soluble guanylyl cyclase in the superficial dorsal horn. J. Comp. Neurol. 2006, 495:668-678.
    • (2006) J. Comp. Neurol. , vol.495 , pp. 668-678
    • Ding, J.D.1    Weinberg, R.J.2
  • 10
    • 39349090970 scopus 로고    scopus 로고
    • NO/cGMP-dependent modulation of synaptic transmission
    • Feil R., Kleppisch T. NO/cGMP-dependent modulation of synaptic transmission. Handb. Exp. Pharmacol. 2008, 529:560.
    • (2008) Handb. Exp. Pharmacol. , vol.529 , pp. 560
    • Feil, R.1    Kleppisch, T.2
  • 11
    • 77950862981 scopus 로고    scopus 로고
    • Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis
    • Feng Q.X., Wang W., Feng X.Y., Mei X.P., Zhu C., Liu Z.C., Li Y.Q., Dou K.F., Zhao Q.C. Astrocytic activation in thoracic spinal cord contributes to persistent pain in rat model of chronic pancreatitis. Neuroscience 2010, 167:501-509.
    • (2010) Neuroscience , vol.167 , pp. 501-509
    • Feng, Q.X.1    Wang, W.2    Feng, X.Y.3    Mei, X.P.4    Zhu, C.5    Liu, Z.C.6    Li, Y.Q.7    Dou, K.F.8    Zhao, Q.C.9
  • 13
    • 43049176430 scopus 로고    scopus 로고
    • Activation of JNK pathway in persistent pain
    • Gao Y.J., Ji R.R. Activation of JNK pathway in persistent pain. Neurosci. Lett. 2008, 437:180-183.
    • (2008) Neurosci. Lett. , vol.437 , pp. 180-183
    • Gao, Y.J.1    Ji, R.R.2
  • 14
    • 77649274037 scopus 로고    scopus 로고
    • Chemokines, neuronal-glial interactions, and central processing of neuropathic pain
    • Gao Y.J., Ji R.R. Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. Pharmacol. Ther. 2010, 126:56-68.
    • (2010) Pharmacol. Ther. , vol.126 , pp. 56-68
    • Gao, Y.J.1    Ji, R.R.2
  • 15
    • 74849124570 scopus 로고    scopus 로고
    • The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition
    • Gao Y.J., Xu Z.Z., Liu Y.C., Wen Y.R., Decosterd I. The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition. Pain 2010, 148:309-319.
    • (2010) Pain , vol.148 , pp. 309-319
    • Gao, Y.J.1    Xu, Z.Z.2    Liu, Y.C.3    Wen, Y.R.4    Decosterd, I.5
  • 16
    • 30844451008 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: NR2B receptor antagonists
    • Gogas K.R. Glutamate-based therapeutic approaches: NR2B receptor antagonists. Curr. Opin. Pharmacol. 2006, 6:68-74.
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 68-74
    • Gogas, K.R.1
  • 18
    • 70350571696 scopus 로고    scopus 로고
    • NMDA receptors are involved in upstream of the spinal JNK activation in morphine antinociceptive tolerance
    • Guo R.X., Zhang M., Liu W., Zhao C.M., Cui Y., Wang C.H., Feng J.Q., Chen P.X. NMDA receptors are involved in upstream of the spinal JNK activation in morphine antinociceptive tolerance. Neurosci. Lett. 2009, 467:95-99.
    • (2009) Neurosci. Lett. , vol.467 , pp. 95-99
    • Guo, R.X.1    Zhang, M.2    Liu, W.3    Zhao, C.M.4    Cui, Y.5    Wang, C.H.6    Feng, J.Q.7    Chen, P.X.8
  • 20
    • 28244472816 scopus 로고    scopus 로고
    • Role of neuronal NR2B subunit-containing NMDA receptor-mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes
    • Kato H., Narita M., Miyatake M., Yajima Y., Suzuki T. Role of neuronal NR2B subunit-containing NMDA receptor-mediated Ca2+ influx and astrocytic activation in cultured mouse cortical neurons and astrocytes. Synapse 2006, 59:10-17.
    • (2006) Synapse , vol.59 , pp. 10-17
    • Kato, H.1    Narita, M.2    Miyatake, M.3    Yajima, Y.4    Suzuki, T.5
  • 21
    • 34548255825 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger
    • Kawasaki T., Kitao T., Nakagawa K., Fujisaki H., Takegawa Y., Koda K., Ago Y., Baba A., Matsuda T. Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger. Glia 2007, 55:1325-1333.
    • (2007) Glia , vol.55 , pp. 1325-1333
    • Kawasaki, T.1    Kitao, T.2    Nakagawa, K.3    Fujisaki, H.4    Takegawa, Y.5    Koda, K.6    Ago, Y.7    Baba, A.8    Matsuda, T.9
  • 22
    • 33644826773 scopus 로고    scopus 로고
    • NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes
    • Lalo U., Pankratov Y., Kirchhoff F., North R.A., Verkhratsky A. NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J. Neurosci. 2006, 26:2673-2683.
    • (2006) J. Neurosci. , vol.26 , pp. 2673-2683
    • Lalo, U.1    Pankratov, Y.2    Kirchhoff, F.3    North, R.A.4    Verkhratsky, A.5
  • 23
    • 79956133332 scopus 로고    scopus 로고
    • Synaptic plasticity and pain: role of ionotropic glutamate receptors
    • Larsson M., Broman J. Synaptic plasticity and pain: role of ionotropic glutamate receptors. Neuroscientist 2010, 10.1177/1073858409349913.
    • (2010) Neuroscientist
    • Larsson, M.1    Broman, J.2
  • 24
    • 0030864283 scopus 로고    scopus 로고
    • Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies
    • Laurie D.J., Bartke I., Schoepfer R., Naujoks K., Seeburg P.H. Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies. Brain Res. Mol. Brain Res. 1997, 51:23-32.
    • (1997) Brain Res. Mol. Brain Res. , vol.51 , pp. 23-32
    • Laurie, D.J.1    Bartke, I.2    Schoepfer, R.3    Naujoks, K.4    Seeburg, P.H.5
  • 25
    • 65949086600 scopus 로고    scopus 로고
    • Inhibiting astrocytic activation: a novel analgesic mechanism of ketamine at the spinal level?
    • Mei X., Wang W., Li Y., Zhang H., Wu S., Xu L. Inhibiting astrocytic activation: a novel analgesic mechanism of ketamine at the spinal level?. J. Neurochem. 2009, 109:1691-1700.
    • (2009) J. Neurochem. , vol.109 , pp. 1691-1700
    • Mei, X.1    Wang, W.2    Li, Y.3    Zhang, H.4    Wu, S.5    Xu, L.6
  • 26
    • 70349481938 scopus 로고    scopus 로고
    • Treatment of neuropathic pain: an overview of recent guidelines
    • O'Connor A.B., Dworkin R.H. Treatment of neuropathic pain: an overview of recent guidelines. Am. J. Med. 2009, 122:S22-S32.
    • (2009) Am. J. Med. , vol.122
    • O'Connor, A.B.1    Dworkin, R.H.2
  • 27
    • 6944257065 scopus 로고    scopus 로고
    • The ultrastructural localisation of the N-methyl-d-aspartate NR2B receptor subunit in rat lumbar spinal cord
    • O'Donnell R., Molon-Noblot S., Laroque P., Rigby M., Smith D. The ultrastructural localisation of the N-methyl-d-aspartate NR2B receptor subunit in rat lumbar spinal cord. Neurosci. Lett. 2004, 371:24-29.
    • (2004) Neurosci. Lett. , vol.371 , pp. 24-29
    • O'Donnell, R.1    Molon-Noblot, S.2    Laroque, P.3    Rigby, M.4    Smith, D.5
  • 28
    • 33846920665 scopus 로고    scopus 로고
    • NMDA receptor subunits: function and pharmacology
    • Paoletti P., Neyton J. NMDA receptor subunits: function and pharmacology. Curr. Opin. Pharmacol. 2007, 7:39-47.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 39-47
    • Paoletti, P.1    Neyton, J.2
  • 29
    • 33745149283 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase (nNOS) modulates the JNK1 activity through redox mechanism: a cGMP independent pathway
    • Park H.S., Huh S.H., Kim M.S., Kim D.Y., Gwag B.J., Cho S.G., Choi E.J. Neuronal nitric oxide synthase (nNOS) modulates the JNK1 activity through redox mechanism: a cGMP independent pathway. Biochem. Biophys. Res. Commun. 2006, 346:408-414.
    • (2006) Biochem. Biophys. Res. Commun. , vol.346 , pp. 408-414
    • Park, H.S.1    Huh, S.H.2    Kim, M.S.3    Kim, D.Y.4    Gwag, B.J.5    Cho, S.G.6    Choi, E.J.7
  • 30
    • 48749124859 scopus 로고    scopus 로고
    • Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus
    • Pei D.S., Song Y.J., Yu H.M., Hu W.W., Du Y., Zhang G.Y. Exogenous nitric oxide negatively regulates c-Jun N-terminal kinase activation via inhibiting endogenous NO-induced S-nitrosylation during cerebral ischemia and reperfusion in rat hippocampus. J. Neurochem. 2008, 106:1952-1963.
    • (2008) J. Neurochem. , vol.106 , pp. 1952-1963
    • Pei, D.S.1    Song, Y.J.2    Yu, H.M.3    Hu, W.W.4    Du, Y.5    Zhang, G.Y.6
  • 33
    • 33646087668 scopus 로고    scopus 로고
    • Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat
    • Ultenius C., Linderoth B., Meyerson B.A., Wallin J. Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. Neurosci. Lett. 2006, 399:85-90.
    • (2006) Neurosci. Lett. , vol.399 , pp. 85-90
    • Ultenius, C.1    Linderoth, B.2    Meyerson, B.A.3    Wallin, J.4
  • 34
    • 43149108624 scopus 로고    scopus 로고
    • Temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain
    • Wang W., Wang W., Wang Y.Y., Huang J., Wu S.X., Li Y.Q. Temporal changes of astrocyte activation and glutamate transporter-1 expression in the spinal cord after spinal nerve ligation-induced neuropathic pain. Anat. Rec. (Hoboken) 2008, 291:513-518.
    • (2008) Anat. Rec. (Hoboken) , vol.291 , pp. 513-518
    • Wang, W.1    Wang, W.2    Wang, Y.Y.3    Huang, J.4    Wu, S.X.5    Li, Y.Q.6
  • 35
    • 70349171800 scopus 로고    scopus 로고
    • Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain
    • Wang W., Wang W., Mei X.P., Huang J., Wei Y.Y., Wang Y.Y., Wu S.X., Li Y.Q. Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain. PLoS ONE 2009, 4:e6973.
    • (2009) PLoS ONE , vol.4
    • Wang, W.1    Wang, W.2    Mei, X.P.3    Huang, J.4    Wei, Y.Y.5    Wang, Y.Y.6    Wu, S.X.7    Li, Y.Q.8
  • 36
    • 25644454237 scopus 로고    scopus 로고
    • NMDA receptor antagonist treatment at the time of nerve injury prevents injury-induced changes in spinal NR1 and NR2B subunit expression and increases the sensitivity of residual pain behaviours to subsequently administered NMDA receptor antagonists
    • Wilson J.A., Garry E.M., Anderson H.A., Rosie R., Colvin L.A., Mitchell R., Fleetwood-Walker S.M. NMDA receptor antagonist treatment at the time of nerve injury prevents injury-induced changes in spinal NR1 and NR2B subunit expression and increases the sensitivity of residual pain behaviours to subsequently administered NMDA receptor antagonists. Pain 2005, 117:421-432.
    • (2005) Pain , vol.117 , pp. 421-432
    • Wilson, J.A.1    Garry, E.M.2    Anderson, H.A.3    Rosie, R.4    Colvin, L.A.5    Mitchell, R.6    Fleetwood-Walker, S.M.7
  • 37
    • 77952955691 scopus 로고    scopus 로고
    • The synaptic connectivity that underlies the noxious transmission and modulation within the superficial dorsal horn of the spinal cord
    • Wu S.X., Wang W., Li H., Wang Y.Y., Feng Y.P., Li Y.Q. The synaptic connectivity that underlies the noxious transmission and modulation within the superficial dorsal horn of the spinal cord. Prog. Neurobiol. 2010, 91:38-54.
    • (2010) Prog. Neurobiol. , vol.91 , pp. 38-54
    • Wu, S.X.1    Wang, W.2    Li, H.3    Wang, Y.Y.4    Feng, Y.P.5    Li, Y.Q.6
  • 38
    • 40049094003 scopus 로고    scopus 로고
    • IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats
    • Zhang R.X., Li A., Liu B., Wang L., Ren K., Zhang H., Berman B.M., Lao L. IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats. Pain 2008, 135:232-239.
    • (2008) Pain , vol.135 , pp. 232-239
    • Zhang, R.X.1    Li, A.2    Liu, B.3    Wang, L.4    Ren, K.5    Zhang, H.6    Berman, B.M.7    Lao, L.8
  • 39
    • 33645460235 scopus 로고    scopus 로고
    • A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
    • Zhuang Z.Y., Wen Y.R., Zhang D.R., Borsello T., Bonny C., Strichartz G.R., Decosterd I., Ji R.R. A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. J. Neurosci. 2006, 26:3551-3560.
    • (2006) J. Neurosci. , vol.26 , pp. 3551-3560
    • Zhuang, Z.Y.1    Wen, Y.R.2    Zhang, D.R.3    Borsello, T.4    Bonny, C.5    Strichartz, G.R.6    Decosterd, I.7    Ji, R.R.8
  • 40
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.