Intrathecal tramadol added to bupivacaine as spinal anesthetic increases analgesic effect of the spinal blockade after major gynecological surgeries

Indian Journal of Pharmacology

Volumn 40, Issue 4, 2008, Pages 180-182

  Chakraborty, Susmita ^a   Chakrabarti, Jayanta ^b   Bhattacharya, Dipasri ^c  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b BANGUR INSTITUTE OF NEUROLOGY   (India)

^c BANKURA SAMMILANI MEDICAL COLLEGE   (India)

Author keywords

Bupivacaine; Gynecological surgeries; Intrathecal administration; Post operative analgesia; Tramadol

Indexed keywords

BUPIVACAINE; TRAMADOL;

ADD ON THERAPY; ADULT; ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; GYNECOLOGIC SURGERY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTENSION; NAUSEA; OBSTETRIC ANALGESIA; PAIN ASSESSMENT; PATIENT MONITORING; POSTOPERATIVE PAIN; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SCORING SYSTEM; SEDATION; SOMNOLENCE; SPINAL ANESTHESIA; VISUAL ANALOG SCALE; VOMITING; XEROSTOMIA;

EID: 53849086840     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.43166     Document Type: Article

References (11)

1. Jacobson L, Chabal C, Brody MC. A dose-response study of intrathecal morphine: Efficacy, duration, optimal dose and side effects. Anesth Analg 1988;67:1082-8.
2. Vickers MD, O.Flaherty D, Szekely SM, Read M, Yoshizumi J. Tramadol: Pain relief by opioid without depression of respiration. Anaesthesia 1992;47:291-6.
3. Tarkkila P, Tuominen M, Lindgren L. Comparison of respiratory effects of tramadol and pethidine. Eur J Anaesthesiol 1998;15:64-8.
4. Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther 1992;260:275-85.
5. Scott LJ, Perry CM. Tramadol: A review of its use in perioperative pain. Drugs 2000;60:139-76.
6. Tsai YC, Chang PJ, Jou IM. Direct tramadol application on sciatic nerve inhibits spinal somatosensory evoked potentials in rats. Anesth Analg 2001;92:1547-51.
7. Crone LA, Conly JM, Clark KM, Crichlow AC, Wardell GC, Zbitnew A, et al. Recurrent herpes simplex virus labialis and the use of epidural morphine in obstetric patients. Anesth Analg 1988;67:318-23.
8. Etches RC, Sandier AN, Daley MD. Respiratory depression and spinal opioids. Can J Anaesth 1989;36:165-85.
9. Morgan M. The rational use of intrathecal and extradural opioids. Br J Anaesth 1989;63:165-88.
10. Prosser DP, Davis A, Booker PD, Murray A. Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery. Br J Anaesth 1997;79:293-6.
11. Bhattacharya R, Dutta B. Postoperative analgesia with local anaesthetic and opioid combinations, using double space CSE technique. Indian J Anaesth 2007;51:409-14.