메뉴 건너뛰기




Volumn 20, Issue 2, 2013, Pages 186-221

Assessment of the antineoplastic potential of chalcones in animal models

Author keywords

Angiogenesis; Animal Models; Antitumor Agents; Cancer; Cell Cycle; Chalcones; Chemoprevention; Cytotoxicity; In Vivo; Invasion; Metastasis; Mitosis; Natural Products; Phytochemicals; Xenograft Experiments

Indexed keywords

2',4' DIHYDROXY 6' METHOXY 3',5' DIMETHYLCHALCONE; 4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; 4' (PARA TOLUENESULFONAMIDO) 4 HYDROXYCHALCONE; 4' ACETAMIDO 4 HYDROXYCHALCONE; 4' PARA AMINOPHENYLSULFONAMIDO; 4' PARA METHOXYPHENYLSULFONAMIDO; ANGELICA KEISKEI EXTRACT; ANTINEOPLASTIC AGENT; CHALCONE; CHALCONE DERIVATIVE; CLEISTOCALYX OPERCULATUS EXTRACT; DOXORUBICIN; FLAVOKAWAIN A; FLAVOKAWAIN B; FLAVOKAWAIN C; FLAVONOID; GLYCYRRHIZA GLABRA EXTRACT; HELICHRYSUM MARACANDICUM EXTRACT; HUMULUS LUPULUS EXTRACT; ISOLIQUIRITIGENIN; KAVA EXTRACT; LONCHOCARPUS NEUROSCAPHA EXTRACT; LOPHIRA ALATA EXTRACT; PLANT EXTRACT; RUSCUS ACULEATUS EXTRACT; SAFFLOWER EXTRACT; SOFALCONE; SORAFENIB; SULFONAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHOANGELOL; XANTHOHUMOL;

EID: 84877960947     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986713804806630     Document Type: Review
Times cited : (12)

References (90)
  • 1
    • 84863981893 scopus 로고    scopus 로고
    • Exploration of the sar of anti-invasive chalcones: Synthesis and biological evaluation of conformationally restricted analogues
    • Roman, B.I.; De Ryck, T.; Dierickx, L.; Vanhoecke, B.W.A.; Katritzky, A.R.; Bracke, M.E.; Stevens, C.V. Exploration of the SAR of anti-invasive chalcones: synthesis and biological evaluation of conformationally restricted analogues. Bioorg. Med. Chem., 2012, 20, 4812-4819
    • (2012) Bioorg. Med. Chem. , vol.20 , pp. 4812-4819
    • Roman, B.I.1    De Ryck, T.2    Dierickx, L.3    Vanhoecke, B.W.A.4    Katritzky, A.R.5    Bracke, M.E.6    Stevens, C.V.7
  • 2
    • 37949045545 scopus 로고    scopus 로고
    • Traditional medicine
    • WHO
    • WHO, Traditional medicine, Fact sheet N134, 2008
    • (2008) Fact sheet , Issue.134
  • 3
    • 0035044430 scopus 로고    scopus 로고
    • The value of plants used in traditional medicine for drug discovery
    • Fabricant, D.S.; Farnsworth, N.R. The value of plants used in traditional medicine for drug discovery. Environ. Health Persp., 2001, 109, 69-75 (Pubitemid 32303231)
    • (2001) Environmental Health Perspectives , vol.109 , Issue.SUPPL. 1 , pp. 69-75
    • Fabricant, D.S.1    Farnsworth, N.R.2
  • 4
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • DOI 10.1021/np068054v
    • Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod., 2007, 70, 461-477 (Pubitemid 46595760)
    • (2007) Journal of Natural Products , vol.70 , Issue.3 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 5
    • 37649012447 scopus 로고    scopus 로고
    • Development trends for new cancer therapeutics and vaccines
    • Reichert, J.M.; Wenger, J.B. Development trends for new cancer therapeutics and vaccines. Drug Disc. Today, 2008, 13, 30-37
    • (2008) Drug Disc. Today , vol.13 , pp. 30-37
    • Reichert, J.M.1    Wenger, J.B.2
  • 6
    • 84877954247 scopus 로고    scopus 로고
    • Results from a search on 'chalcone' resp. ' chalcone' and 'cancer' in Scifinder (web edition), CAS American Chemical Society
    • Results from a search on 'chalcone' resp. 'chalcone' and 'cancer' in Scifinder (web edition), CAS, American Chemical Society, 2011
    • (2011)
  • 7
    • 84877953122 scopus 로고
    • For general reviews of the biological activities of chalcones, consult: (a) Dhar, D.N. The chemistry of chalcones and related compounds Wiley-Interscience: New York
    • For general reviews of the biological activities of chalcones, consult: (a) Dhar, D.N. The chemistry of chalcones and related compounds, Wiley-Interscience: New York, 1981
    • (1981)
  • 9
    • 20144367578 scopus 로고    scopus 로고
    • Chalcones: An update on cytotoxic and chemoprotective properties
    • Go, M.L.; Wu, X. and Liu, X.L. Chalcones: an update on cytotoxic and chemoprotective properties. Curr. Med. Chem., 2005, 12, 483-499 (Pubitemid 40305634)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.4 , pp. 483-499
    • Go, M.L.1    Wu, X.2    Liu, X.L.3
  • 12
    • 0141566685 scopus 로고    scopus 로고
    • Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models
    • Voskoglou-Nomikos, T.; Pater, J.L.; Seymour, L. Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models. Clin. Cancer Res., 2003, 9, 4227-4239 (Pubitemid 37204044)
    • (2003) Clinical Cancer Research , vol.9 , Issue.11 , pp. 4227-4239
    • Voskoglou-Nomikos, T.1    Pater, J.L.2    Seymour, L.3
  • 13
    • 26244450830 scopus 로고    scopus 로고
    • Beer constituents as potential cancer chemopreventive agents
    • DOI 10.1016/j.ejca.2005.04.012
    • Gerhäuser, C. Beer constituents as potential cancer chemopreventive agents. Eur. J. Canc., 2005, 41, 1941-1954 (Pubitemid 41557680)
    • (2005) European Journal of Cancer , vol.41 , Issue.13 , pp. 1941-1954
    • Gerhauser, C.1
  • 15
    • 17844405853 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2′,4′-dihydroxy-6′-methoxy- 3′,5′-dimethylchalcone), a component from Chinese herbal medicine
    • DOI 10.1124/mol.104.009894
    • Zhu, X.-F.; Xie, B.-F.; Zhou, J.-M.; Feng, G.-K.; Liu, Z.-C.; Wei, X.-Y.; Zhang, F.-X.; Liu M.-F.; Zeng, Y.-X. Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone), a component from Chinese herbal medicine. Mol. Pharmacol., 2005, 67, 1444-1450 (Pubitemid 40594143)
    • (2005) Molecular Pharmacology , vol.67 , Issue.5 , pp. 1444-1450
    • Zhu, X.-F.1    Xie, B.-F.2    Zhou, J.-M.3    Feng, G.-K.4    Liu, Z.-C.5    Wei, X.-Y.6    Zhang, F.-X.7    Liu, M.-F.8    Zeng, Y.-X.9
  • 16
    • 70949087763 scopus 로고    scopus 로고
    • Structure-Activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxy chalcone and its analogues as potent nuclear factor b inhibitors and their anticancer activities
    • Srinivasan, B.; Johnson, T.E.; Lad R.; Xing, C. Structure-Activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxy chalcone and its analogues as potent nuclear factor B inhibitors and their anticancer activities. J. Med. Chem., 2009, 52, 7228-7235
    • (2009) J. Med. Chem. , vol.52 , pp. 7228-7235
    • Srinivasan, B.1    Johnson, T.E.2    Lad, R.3    Xing, C.4
  • 17
    • 22244459203 scopus 로고    scopus 로고
    • In vitro and in vivo reversal of cancer cell multidrug resistance by 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone
    • Qian, G.; Ye, C.L.; Wei, D.Z.; Lu Y.H.; Yang, S.L. In vitro and in vivo reversal of cancer cell multidrug resistance by 2',4'-dihydroxy-6'-methoxy-3', 5'-dimethylchalcone. J. Chemother., 2005, 17, 309-314 (Pubitemid 40992270)
    • (2005) Journal of Chemotherapy , vol.17 , Issue.3 , pp. 309-314
    • Qian, F.1    Ye, C.L.2    Wei, D.Z.3    Lu, Y.H.4    Yang, S.L.5
  • 18
    • 21244444905 scopus 로고    scopus 로고
    • In vivo antitumor activity by 2′,4′-dihydroxy-6′- methoxy- 3′,5′-dimethylchalcone in a solid human carcinoma xenograft model
    • DOI 10.1007/s00280-004-0975-y
    • Ye, C.-L.; Liu, J.-W.; Wei, D.-Z.; Lu Y.-H.; F. Qian, In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model. Cancer Chemother. Pharmacol., 2005, 56, 70-74 (Pubitemid 41201758)
    • (2005) Cancer Chemotherapy and Pharmacology , vol.56 , Issue.1 , pp. 70-74
    • Ye, C.-L.1    Liu, J.-W.2    Wei, D.-Z.3    Lu, Y.-H.4    Qian, F.5
  • 19
    • 84877984719 scopus 로고    scopus 로고
    • Method for screening anti-cancer compounds inhibiting function of tm4sf5 and anti-cancer composition containing chalcone compounds
    • Park, K.H.; Lee, J.W.; Ryu, Y.B.; Ryu H.W.; Lee, S.-A. Method for screening anti-cancer compounds inhibiting function of TM4SF5 and anti-cancer composition containing chalcone compounds. WO 2008/069608 A1, 2008
    • (2008) WO 2008/069608 A1
    • Park, K.H.1    Lee, J.W.2    Ryu, Y.B.3    Ryu, H.W.4    Lee, S.-A.5
  • 20
    • 65449132740 scopus 로고    scopus 로고
    • Blockade of four-transmembrane l6 family member 5 (tm4sf5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative
    • Lee, S.-A.; Ryu, H.W.; Kim, Y.M.; Choi, S.; Lee, M.J.; Kwak, T.K.; Kim, H.J.; Cho, M.; Park, K.H.; Lee, J.W. Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative. Hepatology, 2009, 49, 1316-1325
    • (2009) Hepatology , vol.49 , pp. 1316-1325
    • Lee, S.-A.1    Ryu, H.W.2    Kim, Y.M.3    Choi, S.4    Lee, M.J.5    Kwak, T.K.6    Kim, H.J.7    Cho, M.8    Park, K.H.9    Lee, J.W.10
  • 21
    • 79951534453 scopus 로고    scopus 로고
    • Differential inhibition of transmembrane 4 l six family member 5 (tm4sf5)-mediated tumorigenesis by tsahc and sorafenib
    • Lee, S.-A.; Lee, M.-S.; Ryu, H.W.; Kwak, T.K.; Kim, H.; Kang, M.; Jung, O.; Kim, H.J.; Park, K.H.; Lee, J.W. Differential inhibition of transmembrane 4 L six family member 5 (TM4SF5)-mediated tumorigenesis by TSAHC and sorafenib. Cancer Biol. Ther., 2011, 11, 330-336
    • (2011) Cancer Biol. Ther. , vol.11 , pp. 330-336
    • Lee, S.-A.1    Lee, M.-S.2    Ryu, H.W.3    Kwak, T.K.4    Kim, H.5    Kang, M.6    Jung, O.7    Kim, H.J.8    Park, K.H.9    Lee, J.W.10
  • 22
    • 67249152036 scopus 로고    scopus 로고
    • Effects of hydroxy safflor yellow a on blood vessel and mrna expression with vegf and bfgf of transplantation tumor with gastric adenocarcinoma cell line bgc-823 in nude mice]
    • [Article written in Chinese]
    • Xi, S.; Zhang, Q.; Xie, H.; Liu, L.; Liu, C.; Gao, X.; Zhang, J.; Wu, L.; Qian, L.; Deng, X. [Effects of hydroxy safflor yellow A on blood vessel and mRNA expression with VEGF and bFGF of transplantation tumor with gastric adenocarcinoma cell line BGC-823 in nude mice]. Zhongguo Zhong Yao Za Zhi., 2009, 34, 605-610 [Article written in Chinese]
    • (2009) Zhongguo Zhong Yao Za Zhi. , vol.34 , pp. 605-610
    • Xi, S.1    Zhang, Q.2    Xie, H.3    Liu, L.4    Liu, C.5    Gao, X.6    Zhang, J.7    Wu, L.8    Qian, L.9    Deng, X.10
  • 23
    • 77956113476 scopus 로고    scopus 로고
    • Flavokawain b a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth. Int
    • Tang, Y.; Xuesen, L.; Liu, Z.; Simoneau, A.R.; Xie, J.; Zi, X. Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth. Int. J. Cancer, 2010, 127, 1758-1768
    • (2010) J. Cancer , vol.127 , pp. 1758-1768
    • Tang, Y.1    Xuesen, L.2    Liu, Z.3    Simoneau, A.R.4    Xie, J.5    Zi, X.6
  • 25
    • 17144400791 scopus 로고    scopus 로고
    • Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and tumor growth in mice
    • Zi, X.; Simoneau, A.R. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of bax proteindependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res., 2005, 65, 3479-3486 (Pubitemid 40524635)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3479-3486
    • Zi, X.1    Simoneau, A.R.2
  • 26
    • 61749083799 scopus 로고    scopus 로고
    • Effets of the kava chalcone flavokawain a differ in bladder cancer cells with wild-type versus mutant p53
    • Tang, Y.; Simoneau, A.R.; Xie, J.; Shahandeh, B.; Zi, X. Effets of the kava chalcone flavokawain a differ in bladder cancer cells with wild-type versus mutant p53. Cancer Prev. Res., 2008, 1, 439-451
    • (2008) Cancer Prev. Res. , vol.1 , pp. 439-451
    • Tang, Y.1    Simoneau, A.R.2    Xie, J.3    Shahandeh, B.4    Zi, X.5
  • 27
    • 84877986419 scopus 로고
    • Controlling the growth of certain tumor tissue with chalcone derivatives
    • Sunkara, S.P.; Edwards, M.L.; Stemerick, D.M. Controlling the growth of certain tumor tissue with chalcone derivatives. US Patent 4,904,697, 1990
    • (1990) US Patent 4 , vol.904 , pp. 697
    • Sunkara, S.P.1    Edwards, M.L.2    Stemerick, D.M.3
  • 28
    • 35448941897 scopus 로고    scopus 로고
    • Trans-4-lodo,4′-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo
    • DOI 10.1007/s11060-007-9395-2
    • Sasayama, T.; Tanaka, K.; Mizukawa, K.; Kawamura, A.; Kondoh, T.; Hosoda, K.; Kohmura, E. Trans-4-Iodo,4'-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo. J. Neurooncol., 2007, 85, 123-132 (Pubitemid 47629394)
    • (2007) Journal of Neuro-Oncology , vol.85 , Issue.2 , pp. 123-132
    • Sasayama, T.1    Tanaka, K.2    Mizukawa, K.3    Kawamura, A.4    Kondoh, T.5    Hosoda, K.6    Kohmura, E.7
  • 29
    • 78549242930 scopus 로고    scopus 로고
    • 4'-Acetoamido-4-hydroxychalcone, a chalcone derivative, inhibits glioma growth and invasion through regulation of the tropomyosin 1 gene
    • Ku, B.M.; Ryu, H.W.; Lee, Y.K.; Ryu, J.; Jeong, J.Y.; Choi, J.; Cho, H.J.; Park, K.H.; Kang, S.S. 4'-Acetoamido-4-hydroxychalcone, a chalcone derivative, inhibits glioma growth and invasion through regulation of the tropomyosin 1 gene. Biochem. Biophys. Res. Comm., 2010, 402, 525-530
    • (2010) Biochem. Biophys. Res. Comm. , vol.402 , pp. 525-530
    • Ku, B.M.1    Ryu, H.W.2    Lee, Y.K.3    Ryu, J.4    Jeong, J.Y.5    Choi, J.6    Cho, H.J.7    Park, K.H.8    Kang, S.S.9
  • 30
    • 33645814383 scopus 로고    scopus 로고
    • Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-κB and Akt as targets
    • DOI 10.1096/fj.05-5128fje
    • Albini, A.; Dell'Eva, R.; Vené, R.; Ferrari, N.; Buhler, D.R.; Noonan, D.M.; Fassina, G. Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-B and Akt as targets. Faseb J., 2006, 20, 527-529 (Pubitemid 46671238)
    • (2006) FASEB Journal , vol.20 , Issue.3 , pp. 527-529
    • Albini, A.1    Dell'Eva, R.2    Vene, R.3    Ferrari, N.4    Buhler, D.R.5    Noonan, D.M.6    Fassina, G.7
  • 31
    • 0041929913 scopus 로고
    • Lipoxygenase inhibition and tumor promotor inhibition by medicinal plant components.]
    • [article written in Japanese]
    • Kato, R.; Nakadate, A.; Yamamoto, S. [Lipoxygenase inhibition and tumor promotor inhibition by medicinal plant components.] Wakan Iyaku Gakkaishi, 1985, 2, 162-163 [article written in Japanese]
    • (1985) Wakan Iyaku Gakkaishi , vol.2 , pp. 162-163
    • Kato, R.1    Nakadate, A.2    Yamamoto, S.3
  • 32
    • 0022806652 scopus 로고
    • Inhibition of 12-otetradecanoylphorbol-13-Acetate-mediated epidermal ornithine decarboxylase induction and skin tumor promotion by new lipoxygenase inhibitors lacking protein kinase c inhibitory effects
    • Aizu, E.; Nakadate, T.; Yamamoto, S.; Kato R. Inhibition of 12-Otetradecanoylphorbol-13-Acetate-mediated epidermal ornithine decarboxylase induction and skin tumor promotion by new lipoxygenase inhibitors lacking protein kinase C inhibitory effects. Carcinogenesis, 1986, 7, 1809-1812
    • (1986) Carcinogenesis , vol.7 , pp. 1809-1812
    • Aizu, E.1    Nakadate, T.2    Yamamoto, S.3    Kato, R.4
  • 33
    • 0024417545 scopus 로고
    • Inhibition of lipoxygenase inhibitors of 7-bromomethylbenz[a]anthracene- caused epidermal ornithine decarboxylase induction and skin tumor promotion in mice
    • Nakadate, T.; Yamamoto, S.; Aizu, E.; Kato, R. Inhibition by lipoxygenase inhibitors of 7-bromomethylbenz[a]anthracene-caused epidermal ornithine decarboxylase induction and skin tumor promotion in mice. Carcinogenesis, 1989, 10, 2053-2057 (Pubitemid 19280485)
    • (1989) Carcinogenesis , vol.10 , Issue.11 , pp. 2053-2057
    • Nakadate, T.1    Yamamoto, S.2    Aizu, E.3    Kato, R.4
  • 37
    • 0026862630 scopus 로고
    • Chalcone tetramers, lophirachalcone and alatachalcone, from lophira alata as possible anti-tumor promoters. Biosci. Biotech
    • Murakami, A.; Tanaka, S.; Ohigashi, H.; Hirota, M.; Irie, R.; Takeda, N.; Tatematsu, A.; Koshimizu, K. Chalcone tetramers, lophirachalcone and alatachalcone, from Lophira alata as possible anti-tumor promoters. Biosci. Biotech. Biochem., 1992, 56, 769-772
    • (1992) Biochem. , vol.56 , pp. 769-772
    • Murakami, A.1    Tanaka, S.2    Ohigashi, H.3    Hirota, M.4    Irie, R.5    Takeda, N.6    Tatematsu, A.7    Koshimizu, K.8
  • 38
    • 0027520072 scopus 로고
    • Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis
    • DOI 10.1002/ijc.2910550330
    • Satomi, Y. Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis. Int. J. Cancer, 1993, 55, 506-514 (Pubitemid 23300606)
    • (1993) International Journal of Cancer , vol.55 , Issue.3 , pp. 506-514
    • Satomi, Y.1
  • 39
    • 0028012440 scopus 로고
    • Anti-tumorigenic chalcones
    • Shibata, S. Anti-tumorigenic chalcones. Stem Cells, 1994, 12, 44-52 (Pubitemid 24045785)
    • (1994) Stem Cells , vol.12 , Issue.1 , pp. 44-52
    • Shibata, S.1
  • 40
    • 0028071739 scopus 로고
    • Inhibition of tumour promotion and cell proliferation by plant polyphenols
    • Ramanathan, R.; Das, N.P.; Tan, C.H. Inhibition of tumor promotion and cell proliferation by plant polyphenols. Phytother. Res., 1994, 8, 293-296 (Pubitemid 24269747)
    • (1994) Phytotherapy Research , vol.8 , Issue.5 , pp. 293-296
    • Ramanathan, R.1    Das, N.P.2    Tan, C.H.3
  • 41
  • 42
    • 32644448421 scopus 로고    scopus 로고
    • Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects
    • DOI 10.1021/np058080d
    • Akihisa, T.; Tokuda, H.; Hasegawa, D.; Ukiya, M.; Kimura, Y.; Enjo, F.; Suzuki, T.; Nishino, H. Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. J. Nat. Prod., 2006, 69, 38-42 (Pubitemid 43241751)
    • (2006) Journal of Natural Products , vol.69 , Issue.1 , pp. 38-42
    • Akihisa, T.1    Tokuda, H.2    Hasegawa, D.3    Ukiya, M.4    Kimura, Y.5    Enjo, F.6    Suzuki, T.7    Nishino, H.8
  • 44
    • 0006274127 scopus 로고
    • Kinetic characteristics of the antineoplastic activity of chalcones on ehrlich's ascetic sarcoma
    • Kabiev, O.K.; Vermenichev, S.M. Kinetic characteristics of the antineoplastic activity of chalcones on Ehrlich's ascetic sarcoma. Izv. Akad. Nauk Kaz. SSR, Ser. Biol., 1971, 9, 72-75
    • (1971) Izv. Akad. Nauk Kaz. SSR, Ser. Biol. , vol.9 , pp. 72-75
    • Kabiev, O.K.1    Vermenichev, S.M.2
  • 46
    • 0025271454 scopus 로고
    • Methyl p-Hydroxyphenyllactate and nuclear type II binding sites in malignant cells: Metabolic fate and mammary tumor growth
    • Markaverich, B.M.; Gregory, R.R.; Alejandro, M.; Kittrell, F.S.; Medina, D.; Clark, J.H.; Varma, M.; Varma, R.S. Methyl p-hydroxyphenyllactate and nuclear type II binding sites in malignant cells: metabolic fate and mammary tumor growth. Cancer Res., 1990, 50, 1470-1478 (Pubitemid 20090457)
    • (1990) Cancer Research , vol.50 , Issue.5 , pp. 1470-1478
    • Markaverich, B.M.1    Gregory, R.R.2    Alejandro, M.3    Kittrell, F.S.4    Medina, D.5    Clark, J.H.6    Varma, M.7    Varma, R.S.8
  • 48
    • 0020594453 scopus 로고
    • Effects of combination estrogen:Cyclophosphamide treatment on the growth of the MXT transplantable mammary tumor in the mouse
    • Markaverich, B.M.; Medina, D.; Clark, J.H. Effects of combination estrogen: cyclophosphamide treatment on the growth of the MXT transplantable mammary tumor in the mouse. Cancer Res., 1983, 43, 3208-3211 (Pubitemid 13061574)
    • (1983) Cancer Research , vol.43 , Issue.7 , pp. 3208-3211
    • Markaverich, B.M.1    Medina, D.2    Clark, J.H.3
  • 49
    • 84877953208 scopus 로고
    • Combination therapy using bioflavonoid compounds with anti-cancer drugs
    • Markaverich, B.M.; Varma, R.S. Combination therapy using bioflavonoid compounds with anti-cancer drugs. WO 93/01824, 1993
    • (1993) WO 93/01824
    • Markaverich, B.M.1    Varma, R.S.2
  • 51
    • 0027956067 scopus 로고
    • Inhibition of carcinogen-induced pulmonary and mammary carcinogenesis by chalcone administered subsequent to carcinogen exposure
    • DOI 10.1016/0304-3835(94)90314-X
    • Wattenberg, L.W.; Coccia, J.B.; Galbraith, A.R. Inhibition of carcinogeninduced pulmonary and mammary carcinogenesis by chalcone administered subsequent to carcinogen exposure. Cancer Lett., 1994, 83, 165-169 (Pubitemid 24253533)
    • (1994) Cancer Letters , vol.83 , Issue.1-2 , pp. 165-169
    • Lee, W.W.1    Coccia, J.B.2    Galbraith, A.R.3
  • 52
    • 0000543460 scopus 로고    scopus 로고
    • Inhibitory effect of dibenzoylmethane (dbm) on 7,12-dimethylbenz[a] anthracene (dmba)-induced mammary tumorigenesis in rodents. Proc. Am. Assoc
    • Lou, Y.-R.; Lu, Y.-P.; Xie, J.-G.; Zhu, B.T.; Thomas, P.E.; Newmark, H.L.; Haung, M.-T. Inhibitory effect of dibenzoylmethane (DBM) on 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis in rodents. Proc. Am. Assoc. Cancer Res., 1999, 40, 652
    • (1999) Cancer Res. , vol.40 , pp. 652
    • Lou, Y.-R.1    Lu, Y.-P.2    Xie, J.-G.3    Zhu, B.T.4    Thomas, P.E.5    Newmark, H.L.6    Haung, M.-T.7
  • 53
    • 0035954823 scopus 로고    scopus 로고
    • Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice
    • DOI 10.1016/S0304-3835(01)00506-7, PII S0304383501005067
    • Lin, C.-C.; Lu, Y.-P.; Lou, Y.-R.; Ho, C.-T.; Newmark, H.H.; MacDonald, C.; Singelatary, K.W.; Huang, M.-T. Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice. Cancer Lett., 2001, 168, 125-132 (Pubitemid 32524273)
    • (2001) Cancer Letters , vol.168 , Issue.2 , pp. 125-132
    • Lin, C.-C.1    Lu, Y.-P.2    Lou, Y.-R.3    Ho, C.-T.4    Newmark, H.H.5    MacDonald, C.6    Singletary, K.W.7    Huang, M.-T.8
  • 54
    • 0031658361 scopus 로고    scopus 로고
    • Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice
    • DOI 10.1093/carcin/19.9.1697
    • Huang, M.-T.; Lou, Y.-R.; Xie, J.G.; Ma, W.; Lu, Y.-P.; Yen, P.; Zhu, B.T.; Newmark, H.; Ho, C.-T. Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethyulbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. Carcinogenesis, 1998, 19, 1697-1700 (Pubitemid 28441876)
    • (1998) Carcinogenesis , vol.19 , Issue.9 , pp. 1697-1700
    • Huang, M.-T.1    Lou, Y.-R.2    Xie, J.G.3    Ma, W.4    Lu, Y.-P.5    Yen, P.6    Zhu, B.T.7    Newmark, H.8    Ho, C.-T.9
  • 55
    • 33645993864 scopus 로고    scopus 로고
    • Quinone reductase induction as a biomarker for cancer chemoprevention
    • Cuendet, M.; Oteham, C.P.; Moon, R.C.; Pezzuto, J.M. Quinone reductase induction as a biomarker for cancer chemoprevention. J. Nat. Prod., 2006, 69, 460-463
    • (2006) J. Nat. Prod. , vol.69 , pp. 460-463
    • Cuendet, M.1    Oteham, C.P.2    Moon, R.C.3    Pezzuto, J.M.4
  • 58
    • 9944237767 scopus 로고    scopus 로고
    • Studies on cancer chemoprevention by traditional folk medicines XXV. Inhibitory effect of isoliquiritigenin on azoxymethane-induced murine colon aberrant crypt focus formation and carcinogenesis
    • DOI 10.1248/bpb.25.247
    • Baba, M.; Asano, R.; Takigami, I.; Takahashi, T.; Ohmura, M.; Okada, Y.; Sugimoto, H.; Arika, T.; Nishino, H.; Okuyama, T. Studies on cancer Chemoprevention by Traditional Folk Medicines XXV. Inhibitory effect of isoliquiritigenin on azoxymethane-induced murine colon aberrant crypt focus formation and carcinogenesis. Biol. Pharm. Bull., 2002, 25, 247-250 (Pubitemid 39592115)
    • (2002) Biological and Pharmaceutical Bulletin , vol.25 , Issue.2 , pp. 247-250
    • Baba, M.1    Asano, R.2    Takigami, I.3    Takahashi, T.4    Ohmura, M.5    Okada, Y.6    Sugimoto, H.7    Arika, T.8    Nishino, H.9    Okuyama, T.10
  • 59
    • 33749048583 scopus 로고    scopus 로고
    • Prevention of colonic aberrant crypt foci by dietary feeding of chalcone and 2-hydroxychalcone in male f344 rats
    • Kohno, H.; Yamaguchi, K.; Taima, M.; Tanaka, T. Prevention of colonic aberrant crypt foci by dietary feeding of chalcone and 2-hydroxychalcone in male F344 rats. J. Toxicol. Pathol., 2002, 15, 137-143
    • (2002) J. Toxicol. Pathol. , vol.15 , pp. 137-143
    • Kohno, H.1    Yamaguchi, K.2    Taima, M.3    Tanaka, T.4
  • 61
    • 3042545271 scopus 로고    scopus 로고
    • 2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development
    • DOI 10.1111/j.1349-7006.2004.tb03230.x
    • Takahashi, T.; Takasuka, N.; Iigo, M.; Baba, M.; Nishino, H.; Tsuda, H.; Okuyama, T. Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development. Cancer Sci. 2004, 95, 448-453 (Pubitemid 38832690)
    • (2004) Cancer Science , vol.95 , Issue.5 , pp. 448-453
    • Takahashi, T.1    Takasuka, N.2    Iigo, M.3    Baba, M.4    Nishino, H.5    Tsuda, H.6    Okuyama, T.7
  • 65
    • 0029946420 scopus 로고    scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin
    • Makita, H.; Tanaka, T.; Fujitsuka, H.; Tatematsu, N.; Satoh, K.; Hara, A.; Mori, H. Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercitin. Cancer Res., 1996, 56, 4904-4909 (Pubitemid 26374427)
    • (1996) Cancer Research , vol.56 , Issue.21 , pp. 4904-4909
    • Makita, H.1    Tanaka, T.2    Fujitsuka, H.3    Tatematsu, N.4    Satoh, K.5    Hara, A.6    Mori, H.7
  • 66
    • 84877990842 scopus 로고    scopus 로고
    • Effects of isoliquirithigenin on the development of preneoplastic liver lesions caused by a cholinedeficient, l-Amino acid-defined diet and on the urinary bladder carcinogenesis by n-butyl-n-(4-hydroxybutyl)nitrosamine in rats
    • Denda, A.; Kitayama, W.; Puatanachokchai, R.; Tsutsumi, M.; Konishi, Y.; Kuniyasu, H.; Baba, M.; Okuyama, T.; Nishino, H. Effects of isoliquirithigenin on the development of preneoplastic liver lesions caused by a cholinedeficient, l-Amino acid-defined diet and on the urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats. J. Toxicol. Pathol., 2003, 16, 201-207
    • (2003) J. Toxicol. Pathol. , vol.16 , pp. 201-207
    • Denda, A.1    Kitayama, W.2    Puatanachokchai, R.3    Tsutsumi, M.4    Konishi, Y.5    Kuniyasu, H.6    Baba, M.7    Okuyama, T.8    Nishino, H.9
  • 68
    • 0038166888 scopus 로고    scopus 로고
    • Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol
    • DOI 10.1002/ijc.11256
    • Kimura, Y.; Baba, K. Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: isolation of an active substance, xanthoangelol. Int. J. Cancer, 2003, 106, 429-437 (Pubitemid 36870408)
    • (2003) International Journal of Cancer , vol.106 , Issue.3 , pp. 429-437
    • Kimura, Y.1    Baba, K.2
  • 69
    • 1842536365 scopus 로고    scopus 로고
    • Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots
    • DOI 10.1055/s-2004-815537
    • Kimura, Y.; Taniguchi, M.; Baba, K. Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots. Planta Med., 2004, 70, 211-219 (Pubitemid 38445186)
    • (2004) Planta Medica , vol.70 , Issue.3 , pp. 211-219
    • Kimura, Y.1    Taniguchi, M.2    Baba, K.3
  • 70
    • 33646440301 scopus 로고    scopus 로고
    • Antiangiogenic and anti-tumor activities of 2'-hydroxy-4'-methoxychalcone
    • Lee, Y.S.; Lim, S.S.; Shin, K.H.; Kim, Y.S.; Ohuchi, K.; Jung, S.H. Antiangiogenic and anti-tumor activities of 2'-hydroxy-4'-methoxychalcone. Biol. Pharm. Bull., 2006, 29, 1028-1031
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1028-1031
    • Lee, Y.S.1    Lim, S.S.2    Shin, K.H.3    Kim, Y.S.4    Ohuchi, K.5    Jung, S.H.6
  • 71
    • 84878001826 scopus 로고    scopus 로고
    • Flavokawains a and b: Chemopreventive constituents of kava against lung tumorigenesis
    • Devision of Medicinal Chemistry, Philadelphia, USA
    • Johnson, T.E. Flavokawains A and B: Chemopreventive constituents of kava against lung tumorigenesis. Poster presented at the 236th ACS National Meeting, Devision of Medicinal Chemistry, Philadelphia, USA, 2008
    • (2008) Poster presented at the 236th ACS National Meeting
    • Johnson, T.E.1
  • 78
    • 0342749274 scopus 로고    scopus 로고
    • Effect of e-2-(4'-methoxybenzylidene)-1-benzosuberone on the 7,12-dimethylbenz[a]anthracene-induced onco/ suppressor gene action in vivo i: A 24-hour experiment
    • Perjési, P.; Bayer, Z.; Ember I. Effect of E-2-(4'- methoxybenzylidene)-1-benzosuberone on the 7,12-dimethylbenz[a]anthracene- induced onco/ suppressor gene action in vivo I: a 24-hour experiment. Anticancer Res., 2000, 20, 475-482
    • (2000) Anticancer Res. , vol.20 , pp. 475-482
    • Perjési, P.1    Bayer, Z.2    Ember, I.3
  • 79
    • 0033856684 scopus 로고    scopus 로고
    • Effect of E-2-(4'-methoxybenzylidene)-1-benzosuberone on the 7,12-dimethylbenz[a] anthracene-induced onco/suppressor gene action in vivo II: A 48-hour experiment
    • Perjési, P.; Gyöngyi, Z.; Z. Bayer Effect of E-2-(4'-methoxybenzylidene)-1-benzosuberone on the 7,12-dimethylbenz[a] anthracene-induced onco/ suppressor gene action in vivo II: a 48-hour experiment. Anticancer Res., 2000, 20, 1839-1848 (Pubitemid 30628210)
    • (2000) Anticancer Research , vol.20 , Issue.3 A , pp. 1839-1848
    • Perjesi, P.1    Gyongyi, Z.2    Bayer, Z.3
  • 80
    • 0034327338 scopus 로고    scopus 로고
    • The correlation between cancer incidence and kava consumption
    • Steiner, G.G. The correlation between cancer incidence and kava consumption. Hawaii Med. J., 2000, 59, 420-422
    • (2000) Hawaii Med. J. , vol.59 , pp. 420-422
    • Steiner, G.G.1
  • 81
    • 56349138698 scopus 로고    scopus 로고
    • Kava hepatotoxicity: A clinical survey and critical analysis of 26 suspected cases
    • Teschke, R.; Schwarzenboeck, A.; Hennermann, K.H. Kava hepatotoxicity: a clinical survey and critical analysis of 26 suspected cases. Eur. J. Gastroenterol. Hepatol., 2008, 20, 1182-1193
    • (2008) Eur. J. Gastroenterol. Hepatol. , vol.20 , pp. 1182-1193
    • Teschke, R.1    Schwarzenboeck, A.2    Hennermann, K.H.3
  • 82
    • 61749084029 scopus 로고    scopus 로고
    • Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone plus benzo[a] pyrene-induced lung tumorigenesis in a/j mice
    • Johnson, T.E.; Kassie, F.; O'Sullivan, M.G.; Negia, M.; Hanson, T.E.; Upadhyaya, P.; Ruvolo, P.P.; Hecht, S.S.; Xing, C. Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a] pyrene-induced lung tumorigenesis in A/J mice. Cancer Prev. Res., 2008, 1, 430-438
    • (2008) Cancer Prev. Res. , vol.1 , pp. 430-438
    • Johnson, T.E.1    Kassie, F.2    O'Sullivan, M.G.3    Negia, M.4    Hanson, T.E.5    Upadhyaya, P.6    Ruvolo, P.P.7    Hecht, S.S.8    Xing, C.9
  • 86
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer, C.L.; Weinberg, R.A. A perspective on cancer cell metastasis. Science, 2011, 331, 1559-1564
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 88
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw, S.; Nihal, M.; Ahmad, N. Dose translation from animal to human studies revisited. Faseb J., 2007, 22, 659-661
    • (2007) Faseb J. , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 90
    • 10344262032 scopus 로고    scopus 로고
    • Recent advances in therapeutic chalcones
    • DOI 10.1517/13543776.14.12.1669
    • Ni, L.; Meng, C.Q.; Sikorski, J.A. Recent advances in therapeutic chalcones. Expert Opin. Ther. Patents, 2004, 14, 1669-1691 (Pubitemid 39625100)
    • (2004) Expert Opinion on Therapeutic Patents , vol.14 , Issue.12 , pp. 1669-1691
    • Ni, L.1    Meng, C.Q.2    Sikorski, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.