New 4-maleamic acid and 4-maleamide peptidyl chalcones as potential multitarget drugs for human prostate cancer

Pharmaceutical Research

Volumn 28, Issue 4, 2011, Pages 907-919

  Rodrigues, Juan ^a   Abramjuk, Claudia ^a   Vásquez, Luis ^b   Gamboa, Neira ^b   Domínguez, José ^b   Nitzsche, Bianca ^a,c   Höpfner, Michael ^a   Georgieva, Radostina ^a   Bäumler, Hans ^a   Stephan, Carsten ^a,c   Jung, Klaus ^a,c   Lein, Michael ^a,c   Rabien, Anja ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c Berlin Institute for Urologic Research   (Germany)

Author keywords

angiogenesis; chalcones; LNCaP and PC 3 xenografts; matrix metalloproteinase 9; prostate cancer

Indexed keywords

4 MALEAMIC ACID CHALCONE; 4 MALEAMIDE PEPTIDYLCHALCONE; CHALCONE DERIVATIVE; GELATINASE A; GELATINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL ADHESION; CELL CYCLE ARREST; CELL MIGRATION; CELL VIABILITY; CLONOGENESIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; TUMOR XENOGRAFT;

AMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CHALCONES; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MALEATES; MICE; MICE, NUDE; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PHYSIOLOGIC; PROSTATIC NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79955578453     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0347-8     Document Type: Article

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