Activation of the small G-protein Rac by human rhinovirus attenuates the TLR3/IFN-α axis while promoting CCL2 release in human monocyte-lineage cells

Innate Immunity

Volumn 19, Issue 3, 2013, Pages 278-289

  Schreiber, Michael T ^a   Schuler, Bryce ^a   Li, Luyuan ^a   Hall, David J ^a  

^a LAWRENCE UNIVERSITY   (United States)

Author keywords

CCL2; CCL5; IFN ; MCP 1; Rac; RANTES; TLR3

Indexed keywords

ALPHA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; RAC PROTEIN; RANTES; TOLL LIKE RECEPTOR 3; AUTACOID; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL FUNCTION; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN RHINOVIRUS; INFLAMMATION; MACROPHAGE; MICROENVIRONMENT; MONOCYTE; SEROTYPE; UPREGULATION; CELL CULTURE; IMMUNOLOGY; METABOLISM; PICORNAVIRUS INFECTION; RHINOVIRUS; SIGNAL TRANSDUCTION; VIROLOGY;

CELL LINEAGE; CELLS, CULTURED; CHEMOKINE CCL2; HUMANS; INFLAMMATION MEDIATORS; INTERFERON-ALPHA; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MONOCYTES; MONOMERIC GTP-BINDING PROTEINS; PICORNAVIRIDAE INFECTIONS; RAC GTP-BINDING PROTEINS; RHINOVIRUS; TOLL-LIKE RECEPTOR 3;

EID: 84877786068     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425912460709     Document Type: Article

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