Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway

American Journal of Respiratory Cell and Molecular Biology

Volumn 40, Issue 5, 2009, Pages 610-619

  Zhu, Lingxiang ^a   Lee, Pak Kei ^a   Lee, Wai Ming ^b   Zhao, Yuhua ^a   Yu, Dongfang ^a   Chen, Yin ^a,c  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

Airway epithelium; Mucin; Rhinovirus; TLR3

Indexed keywords

ACTIN; AMPHIREGULIN; DOUBLE STRANDED RNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN; MUCIN 5AC; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSFORMING GROWTH FACTOR ALPHA; EPIDERMAL GROWTH FACTOR; LIGAND; MUC5AC PROTEIN, HUMAN; MYD88 PROTEIN, HUMAN; TICAM1 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN; VIRUS RNA;

AIRWAY OBSTRUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; AUTOCRINE EFFECT; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; GENE INDUCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; METAPLASIA; MOUSE; MUCOCILIARY CLEARANCE; NONHUMAN; PARACRINE SIGNALING; PATHOGENESIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; RHINOVIRUS; SIGNAL TRANSDUCTION; SYMPTOMATOLOGY; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION REGULATION; HELA CELL; METABOLISM; PHYSIOLOGY; RESPIRATORY SYSTEM; VIROLOGY;

RHINOVIRUS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; AUTOCRINE COMMUNICATION; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MICE; MUCIN 5AC; MYELOID DIFFERENTIATION FACTOR 88; PARACRINE COMMUNICATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY SYSTEM; RHINOVIRUS; RNA, VIRAL; TOLL-LIKE RECEPTOR 3;

EID: 65349121396     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0223OC     Document Type: Article

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