메뉴 건너뛰기




Volumn 288, Issue 19, 2013, Pages 13748-13761

MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATOR PROTEIN-1; ALZHEIMER; ALZHEIMER DISEASE; METALLO-PROTEASE; MICRORNAS; NEGATIVE REGULATORS;

EID: 84877699276     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.381392     Document Type: Article
Times cited : (96)

References (70)
  • 2
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypothesis. A genetic perspective
    • Tanzi, R. E., and Bertram, L. (2005) Twenty years of the Alzheimer's disease amyloid hypothesis. A genetic perspective. Cell 120, 545-555
    • (2005) Cell , vol.120 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 4
    • 42149165496 scopus 로고    scopus 로고
    • A closer look at α-secretase
    • Postina, R. (2008) A closer look at α-secretase. Curr. Alzheimer Res 5, 179-186
    • (2008) Curr. Alzheimer Res , vol.5 , pp. 179-186
    • Postina, R.1
  • 6
    • 0346250096 scopus 로고    scopus 로고
    • Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome
    • Bernstein, H. G., Bukowska, A., Krell, D., Bogerts, B., Ansorge, S., and Lendeckel, U. (2003) Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome. J. Neurocytol. 32, 153-160
    • (2003) J. Neurocytol , vol.32 , pp. 153-160
    • Bernstein, H.G.1    Bukowska, A.2    Krell, D.3    Bogerts, B.4    Ansorge, S.5    Lendeckel, U.6
  • 9
    • 77956392552 scopus 로고    scopus 로고
    • ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
    • Kuhn, P. H., Wang, H., Dislich, B., Colombo, A., Zeitschel, U., Ellwart, J. W., Kremmer, E., Rossner, S., and Lichtenthaler, S. F. (2010) ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons. EMBO J. 29, 3020-3032
    • (2010) EMBO J , vol.29 , pp. 3020-3032
    • Kuhn, P.H.1    Wang, H.2    Dislich, B.3    Colombo, A.4    Zeitschel, U.5    Ellwart, J.W.6    Kremmer, E.7    Rossner, S.8    Lichtenthaler, S.F.9
  • 10
    • 0033987298 scopus 로고    scopus 로고
    • Levels of α-and β-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients
    • Sennvik, K., Fastbom, J., Blomberg, M., Wahlund, L. O., Winblad, B., and Benedikz, E. (2000) Levels of α-and β-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients. Neurosci. Lett. 278, 169-172
    • (2000) Neurosci. Lett , vol.278 , pp. 169-172
    • Sennvik, K.1    Fastbom, J.2    Blomberg, M.3    Wahlund, L.O.4    Winblad, B.5    Benedikz, E.6
  • 12
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs. Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. (2004) MicroRNAs. Genomics, biogenesis, mechanism, and function. Cell 116, 281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 13
    • 34247364093 scopus 로고    scopus 로고
    • Mechanisms of microRNA-mediated gene regulation in animal cells
    • Nilsen, T. W. (2007) Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet. 23, 243-249
    • (2007) Trends Genet , vol.23 , pp. 243-249
    • Nilsen, T.W.1
  • 14
    • 33747706117 scopus 로고    scopus 로고
    • Non-coding RNAs in the nervous system
    • Mehler, M. F., and Mattick, J. S. (2006) Non-coding RNAs in the nervous system. J. Physiol. 575, 333-341
    • (2006) J. Physiol , vol.575 , pp. 333-341
    • Mehler, M.F.1    Mattick, J.S.2
  • 16
    • 48849103603 scopus 로고    scopus 로고
    • MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation
    • Yu, J. Y., Chung, K. H., Deo, M., Thompson, R. C., and Turner, D. L. (2008) MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp. Cell Res. 314, 2618-2633
    • (2008) Exp. Cell Res , vol.314 , pp. 2618-2633
    • Yu, J.Y.1    Chung, K.H.2    Deo, M.3    Thompson, R.C.4    Turner, D.L.5
  • 19
    • 78649832226 scopus 로고    scopus 로고
    • A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation
    • Laneve, P., Gioia, U., Andriotto, A., Moretti, F., Bozzoni, I., and Caffarelli, E. (2010) A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation. Nucleic Acids Res. 38, 6895-6905
    • (2010) Nucleic Acids Res , vol.38 , pp. 6895-6905
    • Laneve, P.1    Gioia, U.2    Andriotto, A.3    Moretti, F.4    Bozzoni, I.5    Caffarelli, E.6
  • 20
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco, C., Otto, S., Han, J. J., and Mandel, G. (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U.S.A. 103, 2422-2427
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Mandel, G.4
  • 21
    • 63349094897 scopus 로고    scopus 로고
    • Alterations of the microRNA network cause neurodegenerative disease
    • Hébert, S. S., and De Strooper, B. (2009) Alterations of the microRNA network cause neurodegenerative disease. Trends Neurosci. 32, 199-206
    • (2009) Trends Neurosci , vol.32 , pp. 199-206
    • Hébert, S.S.1    De Strooper, B.2
  • 25
    • 77953319294 scopus 로고    scopus 로고
    • MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons
    • Vilardo, E., Barbato, C., Ciotti, M., Cogoni, C., and Ruberti, F. (2010) MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons. J. Biol. Chem. 285, 18344-18351
    • (2010) J. Biol. Chem , vol.285 , pp. 18344-18351
    • Vilardo, E.1    Barbato, C.2    Ciotti, M.3    Cogoni, C.4    Ruberti, F.5
  • 26
    • 79151483332 scopus 로고    scopus 로고
    • MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed
    • Long, J. M., and Lahiri, D. K. (2011) MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed. Biochem. Biophys. Res. Commun. 404, 889-895
    • (2011) Biochem. Biophys. Res. Commun , vol.404 , pp. 889-895
    • Long, J.M.1    Lahiri, D.K.2
  • 27
    • 84855806746 scopus 로고    scopus 로고
    • MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
    • Liu, W., Liu, C., Zhu, J., Shu, P., Yin, B., Gong, Y., Qiang, B., Yuan, J., and Peng, X. (2012) MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol. Aging 33, 522-534
    • (2012) Neurobiol. Aging , vol.33 , pp. 522-534
    • Liu, W.1    Liu, C.2    Zhu, J.3    Shu, P.4    Yin, B.5    Gong, Y.6    Qiang, B.7    Yuan, J.8    Peng, X.9
  • 28
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1
    • Wang, W. X., Rajeev, B. W., Stromberg, A. J., Ren, N., Tang, G., Huang, Q., Rigoutsos, I., and Nelson, P. T. (2008) The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor protein-cleaving enzyme 1. J. Neurosci. 28, 1213-1223
    • (2008) J. Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 30
    • 59049087888 scopus 로고    scopus 로고
    • MicroRNA-298 and microRNA-328 regulate expression of mouse β-amyloid precursor protein-converting enzyme 1
    • Boissonneault, V., Plante, I., Rivest, S., and Provost, P. (2009) MicroRNA-298 and microRNA-328 regulate expression of mouse β-amyloid precursor protein-converting enzyme 1. J. Biol. Chem. 284, 1971-1981
    • (2009) J. Biol. Chem , vol.284 , pp. 1971-1981
    • Boissonneault, V.1    Plante, I.2    Rivest, S.3    Provost, P.4
  • 32
    • 80053648859 scopus 로고    scopus 로고
    • Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis
    • Persengiev, S., Kondova, I., Otting, N., Koeppen, A. H., and Bontrop, R. E. (2011) Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis. Neurobiol. Aging 32, 2316.e2317-2316.e2327
    • (2011) Neurobiol. Aging , vol.32
    • Persengiev, S.1    Kondova, I.2    Otting, N.3    Koeppen, A.H.4    Bontrop, R.E.5
  • 34
    • 70450285075 scopus 로고    scopus 로고
    • MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
    • Bai, S., Nasser, M. W., Wang, B., Hsu, S. H., Datta, J., Kutay, H., Yadav, A., Nuovo, G., Kumar, P., and Ghoshal, K. (2009) MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J. Biol. Chem. 284, 32015-32027
    • (2009) J. Biol. Chem , vol.284 , pp. 32015-32027
    • Bai, S.1    Nasser, M.W.2    Wang, B.3    Hsu, S.H.4    Datta, J.5    Kutay, H.6    Yadav, A.7    Nuovo, G.8    Kumar, P.9    Ghoshal, K.10
  • 39
    • 0023771685 scopus 로고
    • C-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities
    • Halazonetis, T. D., Georgopoulos, K., Greenberg, M. E., and Leder, P. (1988) c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell 55, 917-924
    • (1988) Cell , vol.55 , pp. 917-924
    • Halazonetis, T.D.1    Georgopoulos, K.2    Greenberg, M.E.3    Leder, P.4
  • 40
    • 0024201551 scopus 로고
    • Fos and Jun bind cooperatively to the AP-1 site. Reconstitution in vitro
    • Rauscher, F. J., 3rd, Voulalas, P. J., Franza, B. R., Jr., and Curran, T. (1988) Fos and Jun bind cooperatively to the AP-1 site. Reconstitution in vitro. Genes Dev. 2, 1687-1699
    • (1988) Genes Dev , vol.2 , pp. 1687-1699
    • Rauscher III, F.J.1    Voulalas, P.J.2    Franza Jr., B.R.3    Curran, T.4
  • 41
    • 0023782359 scopus 로고
    • The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes
    • Chiu, R., Boyle, W. J., Meek, J., Smeal, T., Hunter, T., and Karin, M. (1988) The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54, 541-552
    • (1988) Cell , vol.54 , pp. 541-552
    • Chiu, R.1    Boyle, W.J.2    Meek, J.3    Smeal, T.4    Hunter, T.5    Karin, M.6
  • 42
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated transacting factor
    • Angel, P., Imagawa, M., Chiu, R., Stein, B., Imbra, R. J., Rahmsdorf, H. J., Jonat, C., Herrlich, P., and Karin, M. (1987) Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated transacting factor. Cell 49, 729-739
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 43
    • 0023611441 scopus 로고
    • Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
    • Lee, W., Mitchell, P., and Tjian, R. (1987) Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49, 741-752
    • (1987) Cell , vol.49 , pp. 741-752
    • Lee, W.1    Mitchell, P.2    Tjian, R.3
  • 44
    • 0029133850 scopus 로고
    • Differential induction of immediate early gene proteins in cultured neurons by β-amyloid (Aβ). Association of c-Jun with A β-induced apoptosis
    • Anderson, A. J., Pike, C. J., and Cotman, C. W. (1995) Differential induction of immediate early gene proteins in cultured neurons by β-amyloid (Aβ). Association of c-Jun with A β-induced apoptosis. J. Neurochem. 65, 1487-1498
    • (1995) J. Neurochem , vol.65 , pp. 1487-1498
    • Anderson, A.J.1    Pike, C.J.2    Cotman, C.W.3
  • 47
    • 62249200515 scopus 로고    scopus 로고
    • Expression of inflammatory genes induced by β-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
    • Vukic, V., Callaghan, D., Walker, D., Lue, L. F., Liu, Q. Y., Couraud, P. O., Romero, I. A., Weksler, B., Stanimirovic, D. B., and Zhang, W. (2009) Expression of inflammatory genes induced by β-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiol. Dis. 34, 95-106
    • (2009) Neurobiol. Dis , vol.34 , pp. 95-106
    • Vukic, V.1    Callaghan, D.2    Walker, D.3    Lue, L.F.4    Liu, Q.Y.5    Couraud, P.O.6    Romero, I.A.7    Weksler, B.8    Stanimirovic, D.B.9    Zhang, W.10
  • 49
    • 0037112194 scopus 로고    scopus 로고
    • Amyloid-β induces Smac release via AP-1/Bim activation in cerebral endothelial cells
    • Yin, K. J., Lee, J. M., Chen, S. D., Xu, J., and Hsu, C. Y. (2002) Amyloid-β induces Smac release via AP-1/Bim activation in cerebral endothelial cells. J. Neurosci. 22, 9764-9770
    • (2002) J. Neurosci , vol.22 , pp. 9764-9770
    • Yin, K.J.1    Lee, J.M.2    Chen, S.D.3    Xu, J.4    Hsu, C.Y.5
  • 50
    • 0027332081 scopus 로고
    • β-amyloid-(1-42) is a major component of cerebrovascular amyloid deposits. Implications for the pathology of Alzheimer disease
    • Roher, A. E., Lowenson, J. D., Clarke, S., Woods, A. S., Cotter, R. J., Gowing, E., and Ball, M. J. (1993) β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits. Implications for the pathology of Alzheimer disease. Proc. Natl. Acad. Sci. U.S.A. 90, 10836-10840
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10836-10840
    • Roher, A.E.1    Lowenson, J.D.2    Clarke, S.3    Woods, A.S.4    Cotter, R.J.5    Gowing, E.6    Ball, M.J.7
  • 51
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease. Genes, proteins, and therapy
    • Selkoe, D. J. (2001) Alzheimer's disease. Genes, proteins, and therapy. Physiol. Rev. 81, 741-766
    • (2001) Physiol. Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 53
    • 77957225240 scopus 로고    scopus 로고
    • Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death
    • Zhang, X., Wang, X., Zhu, H., Zhu, C., Wang, Y., Pu, W. T., Jegga, A. G., and Fan, G. C. (2010) Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J. Mol. Cell. Cardiol. 49, 841-850
    • (2010) J. Mol. Cell. Cardiol , vol.49 , pp. 841-850
    • Zhang, X.1    Wang, X.2    Zhu, H.3    Zhu, C.4    Wang, Y.5    Pu, W.T.6    Jegga, A.G.7    Fan, G.C.8
  • 54
    • 0034624781 scopus 로고    scopus 로고
    • A century of cognitive decline
    • Yankner, B. A. (2000) A century of cognitive decline. Nature 404, 125
    • (2000) Nature , vol.404 , pp. 125
    • Yankner, B.A.1
  • 55
    • 84856496197 scopus 로고    scopus 로고
    • Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
    • de la Monte, S. M. (2012) Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Curr. Alzheimer Res. 9, 35-66
    • (2012) Curr. Alzheimer Res , vol.9 , pp. 35-66
    • De La Monte, S.M.1
  • 56
    • 79960932477 scopus 로고    scopus 로고
    • MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus
    • Karolina, D. S., Armugam, A., Tavintharan, S., Wong, M. T., Lim, S. C., Sum, C. F., and Jeyaseelan, K. (2011) MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus. PLoS One 6, e22839
    • (2011) PLoS One , vol.6
    • Karolina, D.S.1    Armugam, A.2    Tavintharan, S.3    Wong, M.T.4    Lim, S.C.5    Sum, C.F.6    Jeyaseelan, K.7
  • 57
    • 24644483112 scopus 로고    scopus 로고
    • Genomic structure and functional characterization of the human ADAM10 promoter
    • Prinzen, C., Müller, U., Endres, K., Fahrenholz, F., and Postina, R. (2005) Genomic structure and functional characterization of the human ADAM10 promoter. FASEB J. 19, 1522-1524
    • (2005) FASEB J , vol.19 , pp. 1522-1524
    • Prinzen, C.1    Müller, U.2    Endres, K.3    Fahrenholz, F.4    Postina, R.5
  • 58
    • 77955046461 scopus 로고    scopus 로고
    • SIRT1 suppresses β-amyloid production by activating the α-secretase gene ADAM10
    • Donmez, G., Wang, D., Cohen, D. E., and Guarente, L. (2010) SIRT1 suppresses β-amyloid production by activating the α-secretase gene ADAM10. Cell 142, 320-332
    • (2010) Cell , vol.142 , pp. 320-332
    • Donmez, G.1    Wang, D.2    Cohen, D.E.3    Guarente, L.4
  • 59
    • 80755187822 scopus 로고    scopus 로고
    • The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma
    • Doberstein, K., Pfeilschifter, J., and Gutwein, P. (2011) The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma. Carcinogenesis 32, 1713-1723
    • (2011) Carcinogenesis , vol.32 , pp. 1713-1723
    • Doberstein, K.1    Pfeilschifter, J.2    Gutwein, P.3
  • 63
    • 0037113352 scopus 로고    scopus 로고
    • Levels of β-secretase BACE and α-secretase ADAM10 mRNAs in Alzheimer hippocampus
    • Gatta, L. B., Albertini, A., Ravid, R., and Finazzi, D. (2002) Levels of β-secretase BACE and α-secretase ADAM10 mRNAs in Alzheimer hippocampus. Neuroreport 13, 2031-2033
    • (2002) Neuroreport , vol.13 , pp. 2031-2033
    • Gatta, L.B.1    Albertini, A.2    Ravid, R.3    Finazzi, D.4
  • 64
    • 79951469197 scopus 로고    scopus 로고
    • AP-1-dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells
    • Misawa, A., Katayama, R., Koike, S., Tomida, A., Watanabe, T., and Fujita, N. (2010) AP-1-dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells. Oncol. Res. 19, 23-33
    • (2010) Oncol. Res , vol.19 , pp. 23-33
    • Misawa, A.1    Katayama, R.2    Koike, S.3    Tomida, A.4    Watanabe, T.5    Fujita, N.6
  • 65
    • 84863236989 scopus 로고    scopus 로고
    • MiR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma
    • Zhu, Q., Wang, Z., Hu, Y., Li, J., Li, X., Zhou, L., and Huang, Y. (2012) miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma. Oncol. Rep. 27, 1660-1668
    • (2012) Oncol. Rep , vol.27 , pp. 1660-1668
    • Zhu, Q.1    Wang, Z.2    Hu, Y.3    Li, J.4    Li, X.5    Zhou, L.6    Huang, Y.7
  • 66
    • 79954987841 scopus 로고    scopus 로고
    • NF-κB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells
    • Galardi, S., Mercatelli, N., Farace, M. G., and Ciafrè, S. A. (2011) NF-κB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. Nucleic Acids Res. 39, 3892-3902
    • (2011) Nucleic Acids Res , vol.39 , pp. 3892-3902
    • Galardi, S.1    Mercatelli, N.2    Farace, M.G.3    Ciafrè, S.A.4
  • 67
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu, X., Raina, A. K., Rottkamp, C. A., Aliev, G., Perry, G., Boux, H., and Smith, M. A. (2001) Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76, 435-441
    • (2001) J. Neurochem , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7
  • 68
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death. Identification of c-jun as necessary for neuronal apoptosis
    • Estus, S., Zaks, W. J., Freeman, R. S., Gruda, M., Bravo, R., and Johnson, E. M., Jr. (1994) Altered gene expression in neurons during programmed cell death. Identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727
    • (1994) J. Cell Biol , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson Jr., E.M.6
  • 69
    • 0029012476 scopus 로고
    • A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
    • Ham, J., Babij, C., Whitfield, J., Pfarr, C. M., Lallemand, D., Yaniv, M., and Rubin, L. L. (1995) A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14, 927-939
    • (1995) Neuron , vol.14 , pp. 927-939
    • Ham, J.1    Babij, C.2    Whitfield, J.3    Pfarr, C.M.4    Lallemand, D.5    Yaniv, M.6    Rubin, L.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.