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Volumn 87, Issue 6, 2012, Pages

The role of hypoxia and hypoxia-inducible factor-1alpha in preeclampsia pathogenesis

Author keywords

Angiogenesis; Angiotensin II receptor type I autoimmune antibody; Endothelin ,1 hypoxia, hypoxia inducible factor 1 (HIF1A; HIF 1a); Preeclampsia; Soluble endoglin; Solublefms like tyrosine kinase 1 (sFLT 1)

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; AUTOANTIBODY; ENDOTHELIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; AGTR1 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; FLT1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; VASCULOTROPIN RECEPTOR 1;

EID: 84877666331     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.112.102723     Document Type: Short Survey
Times cited : (182)

References (104)
  • 1
    • 70349667016 scopus 로고    scopus 로고
    • The biology of preeclampsia
    • Kanasaki K, Kalluri R. The biology of preeclampsia. Kidney Int 2009; 76(8):831-837.
    • (2009) Kidney Int , vol.76 , Issue.8 , pp. 831-837
    • Kanasaki, K.1    Kalluri, R.2
  • 2
    • 0028879420 scopus 로고
    • Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia
    • Baker PN, Krasnow J, Roberts JM, Yeo KT. Elevated serum levels of vascular endothelial growth factor in patients with preeclampsia. Obstet Gynecol 1995; 86(5):815-821.
    • (1995) Obstet Gynecol , vol.86 , Issue.5 , pp. 815-821
    • Baker, P.N.1    Krasnow, J.2    Roberts, J.M.3    Yeo, K.T.4
  • 4
    • 0033669976 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth factor in preeclamptic and normotensive pregnancy
    • Hunter A, Aitkenhead M, Caldwell C, McCracken G, Wilson D, McClure N. Serum levels of vascular endothelial growth factor in preeclamptic and normotensive pregnancy. Hypertension 2000; 36(6): 965-969.
    • (2000) Hypertension , vol.36 , Issue.6 , pp. 965-969
    • Hunter, A.1    Aitkenhead, M.2    Caldwell, C.3    McCracken, G.4    Wilson, D.5    McClure, N.6
  • 5
    • 0035124911 scopus 로고    scopus 로고
    • Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance
    • Bosio PM, Wheeler T, Anthony F, Conroy R, O'Herlihy C, McKenna P. Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance. Am J Obstet Gynecol 2001; 184(2):146-152.
    • (2001) Am J Obstet Gynecol , vol.184 , Issue.2 , pp. 146-152
    • Bosio, P.M.1    Wheeler, T.2    Anthony, F.3    Conroy, R.4    O'Herlihy, C.5    McKenna, P.6
  • 6
    • 0031055186 scopus 로고    scopus 로고
    • Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and in preeclampsia
    • Lyall F, Greer IA, Boswell F, Fleming R. Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and in preeclampsia. Br J Obstet Gynaecol 1997; 104(2):223-228.
    • (1997) Br J Obstet Gynaecol , vol.104 , Issue.2 , pp. 223-228
    • Lyall, F.1    Greer, I.A.2    Boswell, F.3    Fleming, R.4
  • 7
    • 0001475562 scopus 로고    scopus 로고
    • Selective deficit of angiogenic growth factors characterizes pregnancies complicated by preeclampsia
    • Reuvekamp A, Velsing-Aarts FV, Poulina IE, Capello JJ, Duits AJ. Selective deficit of angiogenic growth factors characterizes pregnancies complicated by preeclampsia. Br J Obstet Gynaecol 1999; 106(10): 1019-1022.
    • (1999) Br J Obstet Gynaecol , vol.106 , Issue.10 , pp. 1019-1022
    • Reuvekamp, A.1    Velsing-Aarts, F.V.2    Poulina, I.E.3    Capello, J.J.4    Duits, A.J.5
  • 8
    • 0034524141 scopus 로고    scopus 로고
    • Reductions of vascular endothelial growth factor and placental growth factor concentrations in severe preeclampsia
    • Livingston JC, Chin R, Haddad B, McKinney ET, Ahokas R, Sibai BM. Reductions of vascular endothelial growth factor and placental growth factor concentrations in severe preeclampsia. Am J Obstet Gynecol 2000; 183(6):1554-1557.
    • (2000) Am J Obstet Gynecol , vol.183 , Issue.6 , pp. 1554-1557
    • Livingston, J.C.1    Chin, R.2    Haddad, B.3    McKinney, E.T.4    Ahokas, R.5    Sibai, B.M.6
  • 9
    • 0037245823 scopus 로고    scopus 로고
    • Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies
    • Taylor RN, Grimwood J, Taylor RS, McMaster MT, Fisher SJ, North RA. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol 2003; 188(1):177-182.
    • (2003) Am J Obstet Gynecol , vol.188 , Issue.1 , pp. 177-182
    • Taylor, R.N.1    Grimwood, J.2    Taylor, R.S.3    McMaster, M.T.4    Fisher, S.J.5    North, R.A.6
  • 10
    • 0031771617 scopus 로고    scopus 로고
    • A vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation
    • Clark DE, Smith SK, He Y, Day KA, Licence DR, Corps AN, Lammoglia R, Charnock-Jones DS. A vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation. Biol Reprod 1998; 59(6):1540-1548.
    • (1998) Biol Reprod , vol.59 , Issue.6 , pp. 1540-1548
    • Clark, D.E.1    Smith, S.K.2    He, Y.3    Day, K.A.4    Licence, D.R.5    Corps, A.N.6    Lammoglia, R.7    Charnock-Jones, D.S.8
  • 11
    • 0033970164 scopus 로고    scopus 로고
    • Amniotic fluid-soluble vascular endothelial growth factor receptor-1 in preeclampsia
    • Vuorela P, Helske S, Hornig C, Alitalo K, Weich H, Halmesmaki E. Amniotic fluid-soluble vascular endothelial growth factor receptor-1 in preeclampsia. Obstet Gynecol 2000; 95(3):353-357.
    • (2000) Obstet Gynecol , vol.95 , Issue.3 , pp. 353-357
    • Vuorela, P.1    Helske, S.2    Hornig, C.3    Alitalo, K.4    Weich, H.5    Halmesmaki, E.6
  • 15
    • 1842532440 scopus 로고    scopus 로고
    • Prospective analysis of placenta growth factor (PlGF) concentrations in the plasma of women with normal pregnancy and pregnancies complicated by preeclampsia
    • Krauss T, Pauer HU, Augustin HG. Prospective analysis of placenta growth factor (PlGF) concentrations in the plasma of women with normal pregnancy and pregnancies complicated by preeclampsia. Hypertens Pregnancy 2004; 23(1):101-111.
    • (2004) Hypertens Pregnancy , vol.23 , Issue.1 , pp. 101-111
    • Krauss, T.1    Pauer, H.U.2    Augustin, H.G.3
  • 16
    • 48249090832 scopus 로고    scopus 로고
    • A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia
    • Sela S, Itin A, Natanson-Yaron S, Greenfield C, Goldman-Wohl D, Yagel S, Keshet E. A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia. Circ Res 2008; 102(12):1566-1574.
    • (2008) Circ Res , vol.102 , Issue.12 , pp. 1566-1574
    • Sela, S.1    Itin, A.2    Natanson-Yaron, S.3    Greenfield, C.4    Goldman-Wohl, D.5    Yagel, S.6    Keshet, E.7
  • 17
    • 67650248719 scopus 로고    scopus 로고
    • A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is upregulated in hypoxia and preeclampsia
    • Thomas CP, Andrews JI, Raikwar NS, Kelley EA, Herse F, Dechend R, Golos TG, Liu KZ. A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is upregulated in hypoxia and preeclampsia. J Clin Endocrinol Metab 2009; 94(7): 2524-2530.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.7 , pp. 2524-2530
    • Thomas, C.P.1    Andrews, J.I.2    Raikwar, N.S.3    Kelley, E.A.4    Herse, F.5    Dechend, R.6    Golos, T.G.7    Liu, K.Z.8
  • 20
    • 37849021866 scopus 로고    scopus 로고
    • A longitudinal study of angiogenic (placental growth factor) and antiangiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate
    • Romero R, Nien JK, Espinoza J, Todem D, Fu W, Chung H, Kusanovic JP, Gotsch F, Erez O, Mazaki-Tovi S, Gomez R, Edwin S, et al. A longitudinal study of angiogenic (placental growth factor) and antiangiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. J Matern Fetal Neonatal Med 2008; 21(1):9-23.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , Issue.1 , pp. 9-23
    • Romero, R.1    Nien, J.K.2    Espinoza, J.3    Todem, D.4    Fu, W.5    Chung, H.6    Kusanovic, J.P.7    Gotsch, F.8    Erez, O.9    Mazaki-Tovi, S.10    Gomez, R.11    Edwin, S.12
  • 21
    • 70350320956 scopus 로고    scopus 로고
    • A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia
    • Kusanovic JP, Romero R, Chaiworapongsa T, Erez O, Mittal P, Vaisbuch E, Mazaki-Tovi S, Gotsch F, Edwin SS, Gomez R, Yeo L, Conde-Agudelo A, et al. A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia. J Matern Fetal Neonatal Med 2009; 22(11): 1021-1038.
    • (2009) J Matern Fetal Neonatal Med , vol.22 , Issue.11 , pp. 1021-1038
    • Kusanovic, J.P.1    Romero, R.2    Chaiworapongsa, T.3    Erez, O.4    Mittal, P.5    Vaisbuch, E.6    Mazaki-Tovi, S.7    Gotsch, F.8    Edwin, S.S.9    Gomez, R.10    Yeo, L.11    Conde-Agudelo, A.12
  • 22
    • 47749139356 scopus 로고    scopus 로고
    • Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors
    • Lim JH, Kim SY, Park SY, Yang JH, Kim MY, Ryu HM. Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors. Obstet Gynecol 2008; 111(6):1403-1409.
    • (2008) Obstet Gynecol , vol.111 , Issue.6 , pp. 1403-1409
    • Lim, J.H.1    Kim, S.Y.2    Park, S.Y.3    Yang, J.H.4    Kim, M.Y.5    Ryu, H.M.6
  • 23
    • 50349085834 scopus 로고    scopus 로고
    • First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia
    • Baumann MU, Bersinger NA, Mohaupt MG, Raio L, Gerber S, Surbek DV. First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia. Am J Obstet Gynecol 2008; 199(3):266.e1-266.e6.
    • (2008) Am J Obstet Gynecol , vol.199 , Issue.3
    • Baumann, M.U.1    Bersinger, N.A.2    Mohaupt, M.G.3    Raio, L.4    Gerber, S.5    Surbek, D.V.6
  • 25
    • 34047232484 scopus 로고    scopus 로고
    • Predictive value of maternal angiogenic factors in second trimester pregnancies with abnormal uterine perfusion
    • Stepan H, Unversucht A, Wessel N, Faber R. Predictive value of maternal angiogenic factors in second trimester pregnancies with abnormal uterine perfusion. Hypertension 2007; 49(4):818-824.
    • (2007) Hypertension , vol.49 , Issue.4 , pp. 818-824
    • Stepan, H.1    Unversucht, A.2    Wessel, N.3    Faber, R.4
  • 27
    • 84861094112 scopus 로고    scopus 로고
    • Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fmslike tyrosine kinase 1 and soluble endoglin in the prediction of preeclampsia: a systematic review and meta-analysis
    • Kleinrouweler CE, Wiegerinck MM, Ris-Stalpers C, Bossuyt PM, van der Post JA, von Dadelszen P, Mol BW, Pajkrt E. Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fmslike tyrosine kinase 1 and soluble endoglin in the prediction of preeclampsia: a systematic review and meta-analysis. BJOG 2012; 119(7):778-787.
    • (2012) BJOG , vol.119 , Issue.7 , pp. 778-787
    • Kleinrouweler, C.E.1    Wiegerinck, M.M.2    Ris-Stalpers, C.3    Bossuyt, P.M.4    van der Post, J.A.5    von Dadelszen, P.6    Mol, B.W.7    Pajkrt, E.8
  • 29
    • 77957340865 scopus 로고    scopus 로고
    • Screening for preeclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women
    • Audibert F, Boucoiran I, An N, Aleksandrov N, Delvin E, Bujold E, Rey E. Screening for preeclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women. Am J Obstet Gynecol 2010; 203(4):383.e1-383.e8.
    • (2010) Am J Obstet Gynecol , vol.203 , Issue.4
    • Audibert, F.1    Boucoiran, I.2    An, N.3    Aleksandrov, N.4    Delvin, E.5    Bujold, E.6    Rey, E.7
  • 31
    • 57349093026 scopus 로고    scopus 로고
    • Maternal serum placental growth factor at 11 + 0 to 13 + 6 weeks of gestation in the prediction of preeclampsia
    • Akolekar R, Zaragoza E, Poon LC, Pepes S, Nicolaides KH. Maternal serum placental growth factor at 11 + 0 to 13 + 6 weeks of gestation in the prediction of preeclampsia. Ultrasound Obstet Gynecol 2008; 32(6): 732-739.
    • (2008) Ultrasound Obstet Gynecol , vol.32 , Issue.6 , pp. 732-739
    • Akolekar, R.1    Zaragoza, E.2    Poon, L.C.3    Pepes, S.4    Nicolaides, K.H.5
  • 33
    • 62949129110 scopus 로고    scopus 로고
    • Intricacies of bevacizumab-induced toxicities and their management
    • Gressett SM, Shah SR. Intricacies of bevacizumab-induced toxicities and their management. Ann Pharmacother 2009; 43(3):490-501.
    • (2009) Ann Pharmacother , vol.43 , Issue.3 , pp. 490-501
    • Gressett, S.M.1    Shah, S.R.2
  • 35
    • 84870996755 scopus 로고    scopus 로고
    • Bevacizumab-mediated interference with VEGF signaling is sufficient to induce a preeclampsia-like syndrome in nonpregnant women
    • Cross SN, Ratner E, Rutherford TJ, Schwartz PE, Norwitz ER. Bevacizumab-mediated interference with VEGF signaling is sufficient to induce a preeclampsia-like syndrome in nonpregnant women. Rev Obstet Gynecol 2012; 5(1):2-8.
    • (2012) Rev Obstet Gynecol , vol.5 , Issue.1 , pp. 2-8
    • Cross, S.N.1    Ratner, E.2    Rutherford, T.J.3    Schwartz, P.E.4    Norwitz, E.R.5
  • 36
    • 0142023866 scopus 로고    scopus 로고
    • Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
    • Rajagopalan S, Mohler ER III, Lederman RJ, Mendelsohn FO, Saucedo JF, Goldman CK, Blebea J, Macko J, Kessler PD, Rasmussen HS, Annex BH. Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation 2003; 108(16):1933-1938.
    • (2003) Circulation , vol.108 , Issue.16 , pp. 1933-1938
    • Rajagopalan, S.1    Mohler, E.R.2    Lederman, R.J.3    Mendelsohn, F.O.4    Saucedo, J.F.5    Goldman, C.K.6    Blebea, J.7    Macko, J.8    Kessler, P.D.9    Rasmussen, H.S.10    Annex, B.H.11
  • 38
    • 0026740533 scopus 로고
    • Renin-aldosterone relationships in pregnancy-induced hypertension
    • Brown MA, Zammit VC, Mitar DA, Whitworth JA. Renin-aldosterone relationships in pregnancy-induced hypertension. Am J Hypertens 1992; 5(6 pt 1):366-371.
    • (1992) Am J Hypertens , vol.5 , Issue.6 PART 1 , pp. 366-371
    • Brown, M.A.1    Zammit, V.C.2    Mitar, D.A.3    Whitworth, J.A.4
  • 39
    • 0034755027 scopus 로고    scopus 로고
    • Management of hypertensive crises: the scientific basis for treatment decisions
    • Blumenfeld JD, Laragh JH. Management of hypertensive crises: the scientific basis for treatment decisions. Am J Hypertens 2001; 14(11 pt 1):1154-1167.
    • (2001) Am J Hypertens , vol.14 , Issue.11 PART 1 , pp. 1154-1167
    • Blumenfeld, J.D.1    Laragh, J.H.2
  • 40
    • 0015820627 scopus 로고
    • A study of angiotensin II pressor response throughout primigravid pregnancy
    • Gant NF, Daley GL, Chand S, Whalley PJ, MacDonald PC. A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest 1973; 52(11):2682-2689.
    • (1973) J Clin Invest , vol.52 , Issue.11 , pp. 2682-2689
    • Gant, N.F.1    Daley, G.L.2    Chand, S.3    Whalley, P.J.4    MacDonald, P.C.5
  • 42
    • 0037317090 scopus 로고    scopus 로고
    • Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells
    • Xia Y, Wen H, Bobst S, Day MC, Kellems RE. Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells. J Soc Gynecol Investig 2003; 10(2):82-93.
    • (2003) J Soc Gynecol Investig , vol.10 , Issue.2 , pp. 82-93
    • Xia, Y.1    Wen, H.2    Bobst, S.3    Day, M.C.4    Kellems, R.E.5
  • 43
    • 4644342247 scopus 로고    scopus 로고
    • Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation
    • Thway TM, Shlykov SG, Day MC, Sanborn BM, Gilstrap LC III, Xia Y, Kellems RE. Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation. Circulation 2004; 110(12):1612-1619.
    • (2004) Circulation , vol.110 , Issue.12 , pp. 1612-1619
    • Thway, T.M.1    Shlykov, S.G.2    Day, M.C.3    Sanborn, B.M.4    Gilstrap, L.C.5    Xia, Y.6    Kellems, R.E.7
  • 45
    • 74949106574 scopus 로고    scopus 로고
    • Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severity
    • Siddiqui AH, Irani RA, Blackwell SC, Ramin SM, Kellems RE, Xia Y. Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severity. Hypertension 2010; 55(2):386-393.
    • (2010) Hypertension , vol.55 , Issue.2 , pp. 386-393
    • Siddiqui, A.H.1    Irani, R.A.2    Blackwell, S.C.3    Ramin, S.M.4    Kellems, R.E.5    Xia, Y.6
  • 46
    • 33846178237 scopus 로고    scopus 로고
    • Angiotensin II induces soluble fms-like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy
    • Zhou CC, Ahmad S, Mi T, Xia L, Abbasi S, Hewett PW, Sun C, Ahmed A, Kellems RE, Xia Y. Angiotensin II induces soluble fms-like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy. Circ Res 2007; 100(1):88-95.
    • (2007) Circ Res , vol.100 , Issue.1 , pp. 88-95
    • Zhou, C.C.1    Ahmad, S.2    Mi, T.3    Xia, L.4    Abbasi, S.5    Hewett, P.W.6    Sun, C.7    Ahmed, A.8    Kellems, R.E.9    Xia, Y.10
  • 47
    • 76649118070 scopus 로고    scopus 로고
    • Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsia
    • Zhou CC, Irani RA, Zhang Y, Blackwell SC, Mi T, Wen J, Shelat H, Geng YJ, Ramin SM, Kellems RE, Xia Y. Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsia. Circulation 2010; 121(3):436-444.
    • (2010) Circulation , vol.121 , Issue.3 , pp. 436-444
    • Zhou, C.C.1    Irani, R.A.2    Zhang, Y.3    Blackwell, S.C.4    Mi, T.5    Wen, J.6    Shelat, H.7    Geng, Y.J.8    Ramin, S.M.9    Kellems, R.E.10    Xia, Y.11
  • 50
    • 0032005060 scopus 로고    scopus 로고
    • Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsia
    • Langer B, Grima M, Coquard C, Bader AM, Schlaeder G, Imbs JL. Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsia. Obstet Gynecol 1998; 91(2):196-202.
    • (1998) Obstet Gynecol , vol.91 , Issue.2 , pp. 196-202
    • Langer, B.1    Grima, M.2    Coquard, C.3    Bader, A.M.4    Schlaeder, G.5    Imbs, J.L.6
  • 53
    • 84858698421 scopus 로고    scopus 로고
    • The relationship between circulating endothelin-1, soluble fms-like tyrosine kinase-1 and soluble endoglin in preeclampsia
    • Aggarwal PK, Chandel N, Jain V, Jha V. The relationship between circulating endothelin-1, soluble fms-like tyrosine kinase-1 and soluble endoglin in preeclampsia. J Hum Hypertens 2012; 26(4):236-241.
    • (2012) J Hum Hypertens , vol.26 , Issue.4 , pp. 236-241
    • Aggarwal, P.K.1    Chandel, N.2    Jain, V.3    Jha, V.4
  • 54
    • 0035090181 scopus 로고    scopus 로고
    • Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure
    • Alexander BT, Rinewalt AN, Cockrell KL, Massey MB, Bennett WA, Granger JP. Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure. Hypertension 2001; 37(2 pt 2):485-489.
    • (2001) Hypertension , vol.37 , Issue.2 PART 2 , pp. 485-489
    • Alexander, B.T.1    Rinewalt, A.N.2    Cockrell, K.L.3    Massey, M.B.4    Bennett, W.A.5    Granger, J.P.6
  • 55
    • 74949098555 scopus 로고    scopus 로고
    • Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant rats
    • Murphy SR, LaMarca BB, Cockrell K, Granger JP. Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant rats. Hypertension 2010; 55(2):394-398.
    • (2010) Hypertension , vol.55 , Issue.2 , pp. 394-398
    • Murphy, S.R.1    LaMarca, B.B.2    Cockrell, K.3    Granger, J.P.4
  • 57
    • 0020319027 scopus 로고
    • Uteroplacental blood flow in preeclampsia measurements with indium-113m and a computer-linked gamma camera
    • Lunell NO, Nylund LE, Lewander R, Sarby B. Uteroplacental blood flow in preeclampsia measurements with indium-113m and a computer-linked gamma camera. Clin Exp Hypertens B 1982; 1(1):105-117.
    • (1982) Clin Exp Hypertens B , vol.1 , Issue.1 , pp. 105-117
    • Lunell, N.O.1    Nylund, L.E.2    Lewander, R.3    Sarby, B.4
  • 58
    • 57549083868 scopus 로고    scopus 로고
    • The placenta in preeclampsia and intrauterine growth restriction
    • Roberts DJ, Post MD. The placenta in preeclampsia and intrauterine growth restriction. J Clin Pathol 2008; 61(12):1254-1260.
    • (2008) J Clin Pathol , vol.61 , Issue.12 , pp. 1254-1260
    • Roberts, D.J.1    Post, M.D.2
  • 59
    • 34447303822 scopus 로고    scopus 로고
    • Human placental hypoxia-inducible factor-1alpha expression correlates with clinical outcomes in chronic hypoxia in vivo
    • Zamudio S, Wu Y, Ietta F, Rolfo A, Cross A, Wheeler T, Post M, Illsley NP, Caniggia I. Human placental hypoxia-inducible factor-1alpha expression correlates with clinical outcomes in chronic hypoxia in vivo. Am J Pathol 2007; 170(6):2171-2179.
    • (2007) Am J Pathol , vol.170 , Issue.6 , pp. 2171-2179
    • Zamudio, S.1    Wu, Y.2    Ietta, F.3    Rolfo, A.4    Cross, A.5    Wheeler, T.6    Post, M.7    Illsley, N.P.8    Caniggia, I.9
  • 61
    • 34248631970 scopus 로고    scopus 로고
    • Effects of reduced uterine perfusion pressure on blood pressure and metabolic factors in pregnant rats
    • Gilbert J, Dukes M, LaMarca B, Cockrell K, Babcock S, Granger J. Effects of reduced uterine perfusion pressure on blood pressure and metabolic factors in pregnant rats. Am J Hypertens 2007; 20(6):686-691.
    • (2007) Am J Hypertens , vol.20 , Issue.6 , pp. 686-691
    • Gilbert, J.1    Dukes, M.2    LaMarca, B.3    Cockrell, K.4    Babcock, S.5    Granger, J.6
  • 63
    • 0027964281 scopus 로고
    • A study of placental bed spiral arteries and trophoblast invasion in normal and severe preeclamptic pregnancies
    • Meekins JW, Pijnenborg R, Hanssens M, McFadyen IR, van Asshe A. A study of placental bed spiral arteries and trophoblast invasion in normal and severe preeclamptic pregnancies. Br J Obstet Gynaecol 1994; 101(8): 669-674.
    • (1994) Br J Obstet Gynaecol , vol.101 , Issue.8 , pp. 669-674
    • Meekins, J.W.1    Pijnenborg, R.2    Hanssens, M.3    McFadyen, I.R.4    van Asshe, A.5
  • 64
    • 59849106572 scopus 로고    scopus 로고
    • Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression
    • Gilbert JS, Gilbert SA, Arany M, Granger JP. Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression. Hypertension 2009; 53(2):399-403.
    • (2009) Hypertension , vol.53 , Issue.2 , pp. 399-403
    • Gilbert, J.S.1    Gilbert, S.A.2    Arany, M.3    Granger, J.P.4
  • 65
    • 36448996940 scopus 로고    scopus 로고
    • Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression
    • Gilbert JS, Babcock SA, Granger JP. Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression. Hypertension 2007; 50(6): 1142-1147.
    • (2007) Hypertension , vol.50 , Issue.6 , pp. 1142-1147
    • Gilbert, J.S.1    Babcock, S.A.2    Granger, J.P.3
  • 66
    • 57449102345 scopus 로고    scopus 로고
    • Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats
    • LaMarca B, Wallukat G, Llinas M, Herse F, Dechend R, Granger JP. Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats. Hypertension 2008; 52(6):1168-1172.
    • (2008) Hypertension , vol.52 , Issue.6 , pp. 1168-1172
    • LaMarca, B.1    Wallukat, G.2    Llinas, M.3    Herse, F.4    Dechend, R.5    Granger, J.P.6
  • 68
    • 4644281668 scopus 로고    scopus 로고
    • Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae
    • Rajakumar A, Brandon HM, Daftary A, Ness R, Conrad KP. Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae. Placenta 2004; 25(10): 763-769.
    • (2004) Placenta , vol.25 , Issue.10 , pp. 763-769
    • Rajakumar, A.1    Brandon, H.M.2    Daftary, A.3    Ness, R.4    Conrad, K.P.5
  • 69
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001; 294(5545):1337-1340.
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 71
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J 2001; 20(18): 5197-5206.
    • (2001) EMBO J , vol.20 , Issue.18 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 73
    • 0036469038 scopus 로고    scopus 로고
    • Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
    • Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML. Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 2002; 295(5556):858-861.
    • (2002) Science , vol.295 , Issue.5556 , pp. 858-861
    • Lando, D.1    Peet, D.J.2    Whelan, D.A.3    Gorman, J.J.4    Whitelaw, M.L.5
  • 74
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon PC, Hirota K, Semenza GL. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 2001; 15(20):2675-2686.
    • (2001) Genes Dev , vol.15 , Issue.20 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 75
    • 0034100836 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)
    • Caniggia I, Mostachfi H, Winter J, Gassmann M, Lye SJ, Kuliszewski M, Post M. Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3). J Clin Invest 2000; 105(5):577-587.
    • (2000) J Clin Invest , vol.105 , Issue.5 , pp. 577-587
    • Caniggia, I.1    Mostachfi, H.2    Winter, J.3    Gassmann, M.4    Lye, S.J.5    Kuliszewski, M.6    Post, M.7
  • 76
    • 0033873636 scopus 로고    scopus 로고
    • Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta
    • Rajakumar A, Conrad KP. Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod 2000; 63(2):559-569.
    • (2000) Biol Reprod , vol.63 , Issue.2 , pp. 559-569
    • Rajakumar, A.1    Conrad, K.P.2
  • 77
    • 0032746177 scopus 로고    scopus 로고
    • Inhibition of TGF-beta 3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies
    • Caniggia I, Grisaru-Gravnosky S, Kuliszewsky M, Post M, Lye SJ. Inhibition of TGF-beta 3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies. J Clin Invest 1999; 103(12): 1641-1650.
    • (1999) J Clin Invest , vol.103 , Issue.12 , pp. 1641-1650
    • Caniggia, I.1    Grisaru-Gravnosky, S.2    Kuliszewsky, M.3    Post, M.4    Lye, S.J.5
  • 80
    • 34347262653 scopus 로고    scopus 로고
    • High-altitude hypoxia and preeclampsia
    • Zamudio S. High-altitude hypoxia and preeclampsia. Front Biosci 2007; 12:2967-2977.
    • (2007) Front Biosci , vol.12 , pp. 2967-2977
    • Zamudio, S.1
  • 82
    • 0033936370 scopus 로고    scopus 로고
    • Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element
    • Minchenko A, Caro J. Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element. Mol Cell Biochem 2000; 208(1-2):53-62.
    • (2000) Mol Cell Biochem , vol.208 , Issue.1-2 , pp. 53-62
    • Minchenko, A.1    Caro, J.2
  • 83
    • 0037113959 scopus 로고    scopus 로고
    • Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways
    • Sanchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabeu C. Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 2002; 277(46):43799-43808.
    • (2002) J Biol Chem , vol.277 , Issue.46 , pp. 43799-43808
    • Sanchez-Elsner, T.1    Botella, L.M.2    Velasco, B.3    Langa, C.4    Bernabeu, C.5
  • 84
    • 38749144767 scopus 로고    scopus 로고
    • Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-beta 3
    • Yinon Y, Nevo O, Xu J, Many A, Rolfo A, Todros T, Post M, Caniggia I. Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-beta 3. Am J Pathol 2008; 172(1):77-85.
    • (2008) Am J Pathol , vol.172 , Issue.1 , pp. 77-85
    • Yinon, Y.1    Nevo, O.2    Xu, J.3    Many, A.4    Rolfo, A.5    Todros, T.6    Post, M.7    Caniggia, I.8
  • 86
    • 78650222706 scopus 로고    scopus 로고
    • Effects of hypoxia-inducible factor-1alpha overexpression in pregnant mice: possible implications for preeclampsia and intrauterine growth restriction
    • Tal R, Shaish A, Barshack I, Polak-Charcon S, Afek A, Volkov A, Feldman B, Avivi C, Harats D. Effects of hypoxia-inducible factor-1alpha overexpression in pregnant mice: possible implications for preeclampsia and intrauterine growth restriction. Am J Pathol 2010; 177(6):2950-2962.
    • (2010) Am J Pathol , vol.177 , Issue.6 , pp. 2950-2962
    • Tal, R.1    Shaish, A.2    Barshack, I.3    Polak-Charcon, S.4    Afek, A.5    Volkov, A.6    Feldman, B.7    Avivi, C.8    Harats, D.9
  • 88
    • 76149146741 scopus 로고    scopus 로고
    • Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions
    • Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R. Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions. Am J Pathol 2010; 176(2):710-720.
    • (2010) Am J Pathol , vol.176 , Issue.2 , pp. 710-720
    • Lee, S.B.1    Wong, A.P.2    Kanasaki, K.3    Xu, Y.4    Shenoy, V.K.5    McElrath, T.F.6    Whitesides, G.M.7    Kalluri, R.8
  • 89
    • 79959377658 scopus 로고    scopus 로고
    • Severe early-onset preeclampsia is not associated with a change in placental catechol O-methyltransferase (COMT) expression
    • Palmer K, Saglam B, Whitehead C, Stock O, Lappas M, Tong S. Severe early-onset preeclampsia is not associated with a change in placental catechol O-methyltransferase (COMT) expression. Am J Pathol 2011; 178(6):2484-2488.
    • (2011) Am J Pathol , vol.178 , Issue.6 , pp. 2484-2488
    • Palmer, K.1    Saglam, B.2    Whitehead, C.3    Stock, O.4    Lappas, M.5    Tong, S.6
  • 90
  • 91
    • 33745703902 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase, cognition, and psychosis: Val158Met and beyond
    • Tunbridge EM, Harrison PJ, Weinberger DR. Catechol-O-methyltransferase, cognition, and psychosis: Val158Met and beyond. Biol Psychiatry 2006; 60(2):141-151.
    • (2006) Biol Psychiatry , vol.60 , Issue.2 , pp. 141-151
    • Tunbridge, E.M.1    Harrison, P.J.2    Weinberger, D.R.3
  • 92
  • 93
    • 67649354548 scopus 로고    scopus 로고
    • JunD and HIF-1alpha mediate transcriptional activation of angiotensinogen by TGF-beta1 in human lung fibroblasts
    • Abdul-Hafez A, Shu R, Uhal BD. JunD and HIF-1alpha mediate transcriptional activation of angiotensinogen by TGF-beta1 in human lung fibroblasts. FASEB J 2009; 23(6):1655-1662.
    • (2009) FASEB J , vol.23 , Issue.6 , pp. 1655-1662
    • Abdul-Hafez, A.1    Shu, R.2    Uhal, B.D.3
  • 95
    • 24144469144 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney
    • Sanchez-Lopez E, Lopez AF, Esteban V, Yague S, Egido J, Ruiz-Ortega M, Alvarez-Arroyo MV. Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney. Antioxid Redox Signal 2005; 7(9-10): 1275-1284.
    • (2005) Antioxid Redox Signal , vol.7 , Issue.9-10 , pp. 1275-1284
    • Sanchez-Lopez, E.1    Lopez, A.F.2    Esteban, V.3    Yague, S.4    Egido, J.5    Ruiz-Ortega, M.6    Alvarez-Arroyo, M.V.7
  • 97
    • 77953811161 scopus 로고    scopus 로고
    • Upregulation of urotensin II receptor in preeclampsia causes in vitro placental release of soluble vascular endothelial growth factor receptor 1 in hypoxia
    • Gould PS, Gu M, Liao J, Ahmad S, Cudmore MJ, Ahmed A, Vatish M. Upregulation of urotensin II receptor in preeclampsia causes in vitro placental release of soluble vascular endothelial growth factor receptor 1 in hypoxia. Hypertension 2010; 56(1):172-178.
    • (2010) Hypertension , vol.56 , Issue.1 , pp. 172-178
    • Gould, P.S.1    Gu, M.2    Liao, J.3    Ahmad, S.4    Cudmore, M.J.5    Ahmed, A.6    Vatish, M.7
  • 98
    • 77955676942 scopus 로고    scopus 로고
    • Hypoxia and preeclampsia: increased expression of urocortin 2 and urocortin 3
    • Imperatore A, Rolfo A, Petraglia F, Challis JR, Caniggia I. Hypoxia and preeclampsia: increased expression of urocortin 2 and urocortin 3. Reprod Sci 2010; 17(9):833-843.
    • (2010) Reprod Sci , vol.17 , Issue.9 , pp. 833-843
    • Imperatore, A.1    Rolfo, A.2    Petraglia, F.3    Challis, J.R.4    Caniggia, I.5
  • 100
    • 40649093020 scopus 로고    scopus 로고
    • Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIFalpha proteins
    • Rajakumar A, Michael HM, Daftary A, Jeyabalan A, Gilmour C, Conrad KP. Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIFalpha proteins. Placenta 2008; 29(3):290-299.
    • (2008) Placenta , vol.29 , Issue.3 , pp. 290-299
    • Rajakumar, A.1    Michael, H.M.2    Daftary, A.3    Jeyabalan, A.4    Gilmour, C.5    Conrad, K.P.6
  • 101
    • 33645058904 scopus 로고    scopus 로고
    • Expression of von Hippel-Lindau (pVHL) protein in placentae from normal pregnant women and women with preeclampsia
    • Rajakumar A, Doty K, Daftary A, Markovic N, Conrad KP. Expression of von Hippel-Lindau (pVHL) protein in placentae from normal pregnant women and women with preeclampsia. Placenta 2006; 27(4-5):411-421.
    • (2006) Placenta , vol.27 , Issue.4-5 , pp. 411-421
    • Rajakumar, A.1    Doty, K.2    Daftary, A.3    Markovic, N.4    Conrad, K.P.5
  • 103
    • 84865751885 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha (HIF-1alpha) gene polymorphisms in Korean patients with preeclampsia
    • Kim SY, Park SY, Lim JH, Lee BY, Yang JH, Ryu HM. Hypoxia inducible factor-1alpha (HIF-1alpha) gene polymorphisms in Korean patients with preeclampsia. J Endocrinol Invest 2012; 35(7):670-675.
    • (2012) J Endocrinol Invest , vol.35 , Issue.7 , pp. 670-675
    • Kim, S.Y.1    Park, S.Y.2    Lim, J.H.3    Lee, B.Y.4    Yang, J.H.5    Ryu, H.M.6


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