Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 4, 2009, Pages

  Zhang, Ruifeng ^a,d   Wu, Yingli ^c   Zhao, Meng ^c   Liu, Chuanxu ^c   Zhou, Lin ^b   Shen, Shaoming ^c   Liao, Shihua ^c   Yang, Kun ^a   Li, Qingyun ^a   Wan, Huanying ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Chinese Academy of Sciences   (China)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

Angiotensin II; Angiotensin converting enzyme 2; Hypoxia; Hypoxia inducible factor 1

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; BETA ACTIN; DIPEPTIDYL CARBOXYPEPTIDASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; ACE PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; HYPOXIA; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; REGULATORY MECHANISM; RNA INTERFERENCE; SMOOTH MUSCLE FIBER; TRANSACTIVATION; UPREGULATION; ANOXIA; CELL CULTURE; CELL MOTION; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANGIOTENSIN II; ANOXIA; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYPERTENSION, PULMONARY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PEPTIDYL-DIPEPTIDASE A; PULMONARY ARTERY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

EID: 70349774464     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90415.2008     Document Type: Article

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