First Trimester Placental Growth Factor and Soluble Fms-Like Tyrosine Kinase 1 and Risk for Preeclampsia

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 2, 2004, Pages 770-775

  Thadhani, Ravi ^a   Mutter, Walter P ^b   Wolf, Myles ^a   Levine, Richard J ^c   Taylor, Robert N ^d   Sukhatme, Vikas P ^b   Ecker, Jeffrey ^a   Karumanchi, S Ananth ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; GROWTH FACTOR; ISOENZYME; PROTEIN TYROSINE KINASE;

ADULT; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DELIVERY; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; MATERNAL HYPERTENSION; MULTIVARIATE ANALYSIS; NEWBORN; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN LOCALIZATION; RISK ASSESSMENT; RISK FACTOR; SERUM; SOLUBILITY; STATISTICAL SIGNIFICANCE;

ADULT; CASE-CONTROL STUDIES; FEMALE; HUMANS; HYPERTENSION; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; MULTIVARIATE ANALYSIS; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; PREGNANCY PROTEINS; PREGNANCY TRIMESTER, FIRST; PROSPECTIVE STUDIES; RISK ASSESSMENT; SOLUBILITY; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 1442303327     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031244     Document Type: Article

References (55)

1. 2000 Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 183:S1-S22
2. Sibai BM, Caritis SN, Thom E, Klebanoff M, McNellis D, Rocco L, Paul RH, Romero R, Witter F 1993 Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. N Engl J Med 329:1213-1218
3. Caritis S, Sibai B, Hauth J, Lindheimer M, VanDorsten P, Klebanoff M, Thom E, Landon M, Paul R, Miodovnik M, Meis P, Dombrowski M, Thurnau G, Walsh S, McNellis D, Roberts JM 1998 Low-dose aspirin to prevent preeclampsia in women at high risk. N Engl J Med 338:701-705
4. CLASP Collaborative Group 1994 CLASP: a randomized trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women. Lancet 343:619-629
5. Sibai BM 1996 Treatment of hypertension in pregnant women. N Engl J Med 335:257-265
6. Levine RJ, Hauth JC, Curet LB, Sibai BM, Catalano PM, Morris CD, DerSimonian R, Esterlitz JR, Raymond EG, Bild DE, Clemens JD, Culter JA 1997 Trial of calcium to prevent preeclampsia. N Engl J Med 337:69-76
7. Chappell LC, Seed PT, Briley AL, Kelley FJ, Lee R, Hunt BJ, Parmar K, Bewley SJ, Shennan AH, Steer PJ, Poston L 1999 Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomized trial. Lancet 354:810-816
8. Conde-Agudelo A, Lede R, Belizan J 1994 Evaluation of methods used in the prediction of hypertensive disorders of pregnancy. Obstet Gynecol Surv 49:210-222
9. Dekker GA, Sibai BM 1991 Early detection of preeclampsia. Am J Obstet Gynecol 165:160-172
10. Thadhani R, Ecker J, Kettyle E, Sandler L, Frigoletto F 2001 Pulse pressure and risk of preeclampsia: a prospective study. Obstet Gynecol 97:515-520
11. Wolf M, Sandler L, Munoz K, Hsu K, Ecker JL, Thadhani R 2002 First trimester insulin resistance and subsequent preeclampsia: a prospective study. J Clin Endocrinol Metab 87:1563-1568
12. Wolf M, Kettyle E, Sandler L, Ecker JL, Roberts J, Thadhani R 2001 Obesity and preeclampsia: the potential role of inflammation. Obstet Gynecol 98:757-762
13. Djurovic S, Clausen T, Wergeland R, Brosstad F, Berg K, Henriksen T 2002 Absence of enhanced systemic inflammatory response at 18 weeks of gestation in women with subsequent pre-eclampsia. BJOG 109:759-764
14. Redman CW, Beilin LJ, Bonnar J, Wilkinson RH 1976 Plasma-urate measurements in predicting fetal death in hypertensive pregnancy. Lancet 1:1370-1373
15. Taylor RN, Grimwood J, Taylor RS, McMaster MT, Fisher SJ, North RA 2003 Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol 188:177-182
16. Dechend R, Homuth V, Wallukat G, Kreuzer J, Park JK, Theuer J, Juepner A, Gulba DC, Mackman N, Haller H, Luft FC 2000 AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor. Circulation 101:2382-2387
17. Roberts JM, Cooper DW 2001 Pathogenesis and genetics of pre-eclampsia. Lancet 357:53-56
18. Roberts JM, Redman CW 1993 Pre-eclampsia: more than pregnancy-induced hypertension. Lancet 341:1447-1451
19. Kauma SW, Bae-Jump V, Walsh SW 1999 Hepatocyte growth factor stimulates trophoblast invasion: a potential mechanism for abnormal placentation in preeclampsia. J Clin Endocrinol Metab 84:4092-4096
20. Zhou Y, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, Alitalo K, Damsky C, Fisher SJ 2002 Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am J Pathol 160:1405-1423
21. Neale D, Demasio K, Illuzi J, Chaiworapongsa T, Romero R, Mor G 2003 Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis. J Matern Fetal Neonatal Med 13:39-44
22. Genbacev O, Zhou Y, Ludlow JW, Fisher SJ 1997 Regulation of human placental development by oxygen tension. Science 277:1669-1672
23. Khong TY, De Wolf F, Robertson WB, Brosens I 1986 Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants. Br J Obstet Gynaecol 93:1049-1059
24. Anson-Cartwright L, Dawson K, Holmyard D, Fisher SJ, Lazzarini RA, Cross JC 2000 The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta. Nat Genet 25:311-314
25. Ziche M, Maglione D, Ribatti D, Morbidelli L, Lago CT, Battisti M, Paoletti I, Barra A, Tucci M, Parise G, Vincenti V, Granger HJ, Viglietto G, Persico MG 1997 Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Invest 76:517-531
26. Torry DS, Wang HS, Wang TH, Caudle MR, Torry RJ 1998 Preeclampsia is associated with reduced serum levels of placenta growth factor. Am J Obstet Gynecol 179:1539-1544
27. Pascoal IF, Lindheimer MD, Nalbantian-Brandt C, Umans JG 1998 Preeclampsia selectively impairs endothelium-dependent relaxation and leads to oscillatory activity in small omental arteries. J Clin Invest 101:464-470
28. Ong CY, Liao AW, Cacho AM, Spencer K, Nicolaides KH 2001 First-trimester maternal serum levels of placenta growth factor as predictor of preeclampsia and fetal growth restriction. Obstet Gynecol 98:608-611
29. Livingston JC, Haddad B, Gorski LA, Neblett P, Ahokas RA, Ramsey R, Sibai BM 2001 Placenta growth factor is not an early marker for the development of severe preeclampsia. Am J Obstet Gynecol 184:1218-1220
30. Polliotti BM, Fry AG, Saller DN, Mooney RA, Cox C, Miller RK 2003 Second-trimester maternal serum placental growth factor and vascular endothelial growth factor for predicting severe, early-onset preeclampsia. Obstet Gynecol 101:1266-1274
31. Tjoa ML, van Vugt JM, Mulders MA, Schutgens RB, Oudejans CB, van Wijk IJ 2001 Plasma placenta growth factor levels in midtrimester pregnancies. Obstet Gynecol 98:600-607
32. Su YN, Lee CN, Cheng WF, Shau WY, Chow SN, Hsieh FJ 2001 Decreased maternal serum placenta growth factor in early second trimester and preeclampsia. Obstet Gynecol 97:898-904
33. Tidwell SC, Ho HN, Chiu WH, Torry RJ, Torry DS 2001 Low maternal serum levels of placenta growth factor as an antecedent of clinical preeclampsia. Am J Obstet Gynecol 184:1267-1272
34. Cooper JC, Sharkey AM, Charnock-Jones DS, Palmer CR, Smith SK 1996 VEGF mRNA levels in placentae from pregnancies complicated by preeclampsia. Br J Obstet Gynaecol 103:1191-1196
35. Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Selke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA 2003 Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111:649-658
36. Koga K, Osuga Y, Yoshino O, Hirota Y, Ruimeng X, Hirata T, Takeda S, Yano T, Tsutsumi O, Taketani Y 2003 Elevated serum soluble vascular endothelial growth factor receptor 1 (sVEGFR-1) levels in women with preeclampsia. J Clin Endocrinol Metab 88:2348-2351
37. American College of Obstericians and Gynecologists 2000 Intrauterine growth restriction. ACOG Practice Bulletin No. 12. Washington, DC: ACOG
38. Rothman KJ, Greenland S 1998 Modern epidemiology. Boston: Little, Brown
39. Livingston JC, Chin R, Haddad B, McKinney ET, Ahokas R, Sibai BM 2000 Reductions of vascular endothelial growth factor and placental growth factor concentrations in severe preeclampsia. Am J Obstet Gynecol 183:1554-1557
40. Reuvekamp A, Velsing-Aarts FV, Poulina IE, Capello JJ, Duits AJ 1999 Selective deficit of angiogenic growth factors characterises pregnancies complicated by pre-eclampsia. Br J Obstet Gynaecol 106:1019-1022
41. Rosner BA 1995 Fundamentals of biostatistics. Belmont, CA: Duxbury Press
42. Roberts JM 2001 Preeclampsia: is there value in assessing before clinically evident disease? Obstet Gynecol 98:596-599
43. Eskenazi B, Fenster L, Sidney S 1991 A multivariate analysis of risk factors for preeclampsia. JAMA 266:237-241
44. Thadhani R, Stampfer MJ, Hunter DJ, Manson JE, Solomon CG, Curhan GC 1999 High body mass index and hypercholesterolemia: risk of hypertensive disorders of pregnancy. Obstet Gynecol 94:543-550
45. Walker JJ 2000 Pre-eclampsia. Lancet 356:1260-1265
46. Geva E, Ginzinger DG, Zaloudek CJ, Moore DH, Byrne A, Jaffe RB 2002 Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2. J Clin Endocrinol Metab 87:4213-4224
47. Jaffe R, Friedman Z 1998 Changes in uterine artery Doppler velocimetry in pregnant patients undergoing glucose tolerance test may predict adverse outcome in later pregnancy: a preliminary study. Fetal Diagn Ther 13:241-243
48. Dawson LM, Parfrey PS, Hefferton D, Dicks EL, Cooper MJ, Young D, Marsden PA 2002 Familial risk of preeclampsia in Newfoundland: a population-based study. J Am Soc Nephrol 13:1901-1906
49. Seely EW, Solomon CG 2003 Insulin resistance and its potential role in pregnancy-induced hypertension. J Clin Endocrinol Metab 88:2393-2398
50. Kaaja R 1998 Insulin resistance syndrome in preeclampsia. Semin Reprod Endocrinol 16:41-46
51. Taufield PA, Ales KL, Resnick LM, Druzin ML, Gertner JM, Laragh JH 1987 Hypocalciuria in preeclampsia. N Engl J Med 316:715-718
52. Kauma S, Takacs P, Scordalakes C, Walsh S, Green K, Peng T 2002 Increased endothelial monocyte chemoattractant protein-1 and interleukin-8 in preeclampsia. Obstet Gynecol 100:706-714
53. Conrad KP, Miles TM, Benyo DF 1998 Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol 40:102-111
54. Benyo DF, Smarason A, Redman CW, Sims C, Conrad KP 2001 Expression of inflammatory cytokines in placentas from women with preeclampsia. J Clin Endocrinol Metab 86:2505-2512
55. Johnson RD, Sadovsky Y, Graham C, Anteby EY, Polakoski KL, Huang X, Nelson DM 1997 The expression and activity of prostaglandin H synthase-2 is enhanced in trophoblast from women with preeclampsia. J Clin Endocrinol Metab 82:3059-3062