Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats

Hypertension

Volumn 58, Issue 1, 2011, Pages 77-84

  Wenzel, Katrin ^a,b   Rajakumar, Augustine ^c   Haase, Hannelore ^b   Geusens, Nele ^d   Hubner, Norbert ^b   Schulz, Herbert ^b   Brewer, Justin ^e   Roberts, Lyndsay ^e   Hubel, Carl A ^f   Herse, Florian ^a,b   Hering, Lydia ^b   Qadri, Fatimunnisa ^a,b   Lindschau, Carsten ^g   Wallukat, Gerd ^b   Pijnenborg, Robert ^d   Heidecke, Harald ^h   Riemekasten, Gabriela ^a   Luft, Friedrich C ^a,b   Muller, Dominik N ^b   Lamarca, Babette ^e   Dechend, Ralf ^a,b   more..

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH   (United States)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h CellTrend   (Germany)

Author keywords

angiotensin II; autoimmune disease; immunology; preeclampsia

Indexed keywords

ALANYLPHENYLALANYLHISTIDYLTYROSYLGLUTAMYLSERYLGLUTAMINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; AUTOANTIBODY; ENDOTHELIN 1; EPITOPE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLOSCLEROSIS; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL RABBIT; EXPLANT; FEMALE; HYPERTENSION; INTRAUTERINE GROWTH RETARDATION; NONHUMAN; PLACENTA CIRCULATION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROTEINURIA; UPREGULATION;

ANGIOTENSIN II; ANIMALS; AUTOANTIBODIES; BLOTTING, WESTERN; CELLS, CULTURED; CRICETINAE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY, ANIMAL; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; RNA;

EID: 79959763514     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.171348     Document Type: Article

References (46)

1. ACOG Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin: diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol. 2002;99:159-167.
2. Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science. 2005;308:1592-1594. (Pubitemid 40807500)
3. Bellamy L, Casas JP, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ. 2007;335:974.
4. Staff AC, Dechend R, Pijnenborg R. Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia-novel aspects for atherosclerosis and future cardiovascular health. Hypertension. 2010;56: 1026-1034.
5. Herse F, Staff AC, Hering L, Muller DN, Luft FC, Dechend R. AT1- receptor autoantibodies and uteroplacental RAS in pregnancy and preeclampsia. J Mol Med. 2008;86:697-703.
6. Shah DM. Role of the renin-angiotensin system in the pathogenesis of preeclampsia. Am J Physiol Renal Physiol. 2005;288:F614-F625. (Pubitemid 40381727)
7. Baker PN, Kilby MD, Broughton Pipkin F. The effect of angiotensin II on platelet intracellular free calcium concentration in human pregnancy. J Hypertens. 1992;10:55-60.
8. Gant NF, Daley GL, Chand S, Whalley PJ, MacDonald PC. A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest. 1973;52:2682-2689.
9. Saxena AR, Karumanchi SA, Brown NJ, Royle CM, McElrath TF, Seely EW. Increased sensitivity to angiotensin II is present postpartum in women with a history of hypertensive pregnancy. Hypertension. 2010; 55:1239-1245.
10. Siddiqui AH, Irani RA, Blackwell SC, Ramin SM, Kellems RE, Xia Y. Angiotensin receptor agonistic autoantibody is highly prevalent in preeclampsia: correlation with disease severity. Hypertension. 2010;55: 386-393.
11. Wallukat G, Homuth V, Fischer T, Lindschau C, Horstkamp B, Jupner A, Baur E, Nissen E, Vetter K, Neichel D, Dudenhausen JW, Haller H, Luft FC. Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. J Clin Invest. 1999;103:945-952. (Pubitemid 29169601)
12. Dechend R, Viedt C, Muller DN, Ugele B, Brandes RP, Wallukat G, Park JK, Janke J, Barta P, Theuer J, Fiebeler A, Homuth V, Dietz R, Haller H, Kreuzer J, Luft FC. AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation. 2003;107:1632-1639. (Pubitemid 36401560)
13. Zhou CC, Zhang Y, Irani RA, Zhang H, Mi T, Popek EJ, Hicks MJ, Ramin SM, Kellems RE, Xia Y. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice. Nat Med. 2008;14: 855-862.
14. Xia Y, Ramin SM, Kellems RE. Potential roles of angiotensin receptoractivating autoantibody in the pathophysiology of preeclampsia. Hypertension. 2007;50:269-275. (Pubitemid 47205769)
15. LaMarca B, Parrish M, Ray LF, Murphy SR, Roberts L, Glover P, Wallukat G, Wenzel K, Cockrell K, Martin JN Jr, Ryan MJ, Dechend R. Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1. Hypertension. 2009;54:905-909.
16. Rose NR. Infection, mimics, and autoimmune disease. J Clin Invest. 2001;107:943-944. (Pubitemid 32323402)
17. Jahns R, Boivin V, Hein L, Triebel S, Angermann CE, Ertl G, Lohse MJ. Direct evidence for a 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy. J Clin Invest. 2004;113: 1419-1429. (Pubitemid 39071697)
18. Wenzel K, Wallukat G, Qadri F, Hubner N, Schulz H, Hummel O, Herse F, Heuser A, Fischer R, Heidecke H, Luft FC, Muller DN, Dietz R, Dechend R. 1A-adrenergic receptor-directed autoimmunity induces left ventricular damage and diastolic dysfunction in rats. PLoS One. 2010;5: e9409.
19. Zhang SL, Du YH, Wang J, Yang LH, Yang XL, Zheng RH, Wu Y, Wang K, Zhang MS, Liu HR. Endothelial dysfunction induced by antibodies against angiotensin AT receptor in immunized rats. Acta Pharmacol Sin. 2010;31:1381-1388.
20. Wenzel K, Haase H, Wallukat G, Derer W, Bartel S, Homuth V, Herse F, Hubner N, Schulz H, Janczikowski M, Lindschau C, Schroeder C, Verlohren S, Morano I, Muller DN, Luft FC, Dietz R, Dechend R, Karczewski P. Potential relevance of-(1)-adrenergic receptor autoantibodies in refractory hypertension. PLoS One. 2008;3:e3742.
21. Dechend R, Gratze P, Wallukat G, Shagdarsuren E, Plehm R, Brasen JH, Fiebeler A, Schneider W, Caluwaerts S, Vercruysse L, Pijnenborg R, Luft FC, Muller DN. Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia. Hypertension. 2005;45:742-746. (Pubitemid 40418375)
22. Geusens N, Hering L, Verlohren S, Luyten C, Drijkoningen K, Taube M, Vercruysse L, Hanssens M, Dechend R, Pijnenborg R. Changes in endovascular trophoblast invasion and spiral artery remodelling at term in a transgenic preeclamptic rat model. Placenta;31:320-326.
23. Rajakumar A, Michael HM, Daftary A, Jeyabalan A, Gilmour C, Conrad KP. Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF- proteins. Placenta. 2008;29:290-299.
24. Geusens N, Verlohren S, Luyten C, Taube M, Hering L, Vercruysse L, Hanssens M, Dudenhausen JW, Dechend R, Pijnenborg R. Endovascular trophoblast invasion, spiral artery remodelling and uteroplacental haemodynamics in a transgenic rat model of pre-eclampsia. Placenta. 2008;29: 614-623.
25. AbdAlla S, Lother H, el Massiery A, Quitterer U. Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness. Nat Med. 2001;7:1003-1009. (Pubitemid 32937379)
26. Herse F, Dechend R, Harsem NK, Wallukat G, Janke J, Qadri F, Hering L, Muller DN, Luft FC, Staff AC. Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia. Hypertension. 2007;49:604-611.
27. Elies R, Fu LX, Eftekhari P, Wallukat G, Schulze W, Granier C, Hjalmarson A, Hoebeke J. Immunochemical and functional characterization of an agonist-like monoclonal antibody against the M2 acetylcholine receptor. Eur J Biochem. 1998;251:659-666. (Pubitemid 28108959)
28. Cruz MA, Dominguez A, Gallardo V, Carrasco G, Miguel P, Gonzalez C. Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. Gynecol Obstet Invest. 2000;50:247-253.
29. Hubel CA, Wallukat G, Wolf M, Herse F, Rajakumar A, Roberts JM, Markovic N, Thadhani R, Luft FC, Dechend R. Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. Hypertension. 2007;49:612-617.
30. Roberts JM, Gammill HS. Preeclampsia: recent insights. Hypertension. 2005;46:1243-1249. (Pubitemid 43189714)
31. Yu T, Khraibi AA. Renal interstitial hydrostatic pressure and natriuretic response to high doses of angiotensin II in pregnant rats. Am J Hypertens. 2006;19:300-305. (Pubitemid 43261513)
32. Yang X, Wang F, Chang H, Zhang S, Yang L, Wang X, Cheng X, Zhang M, Ma XL, Liu H. Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation. J Hypertens. 2008;26:1629-1635.
33. Doyle HA, Mamula MJ. Post-translational protein modifications in antigen recognition and autoimmunity. Trends Immunol. 2001;22: 443-449. (Pubitemid 32709979)
34. Chiu NM, Wang B, Kerksiek KM, Kurlander R, Pamer EG, Wang CR. The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus. J Exp Med. 1999; 190:1869-1878. (Pubitemid 30013852)
35. Lopez PH, Zhang G, Zhang J, Lehmann HC, Griffin JW, Schnaar RL, Sheikh KA. Passive transfer of IgG anti-GM1 antibodies impairs peripheral nerve repair. J Neurosci;30:9533-9541.
36. Iizuka M, Wakamatsu E, Tsuboi H, Nakamura Y, Hayashi T, Matsui M, Goto D, Ito S, Matsumoto I, Sumida T. Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjogren's syndrome-like sialoadenitis. J Autoimmun. 2010;35:383-389.
37. Monneaux F, Dumortier H, Steiner G, Briand JP, Muller S. Murine models of systemic lupus erythematosus: B and T cell responses to spliceosomal ribonucleoproteins in MRL/Fas(lpr) and (NZB x NZW)F(1) lupus mice. Int Immunol. 2001;13:1155-1163. (Pubitemid 32899158)
38. Jacobson L, Polizzi A, Morriss-Kay G, Vincent A. Plasma from human mothers of fetuses with severe arthrogryposis multiplex congenita causes deformities in mice. J Clin Invest. 1999;103:1031-1038. (Pubitemid 29169611)
39. Merrill DC, Karoly M, Chen K, Ferrario CM, Brosnihan KB. Angiotensin-( 1-7) in normal and preeclamptic pregnancy. Endocrine. 2002;18: 239-245.
40. Dragun D, Scornik J, Meier-Kriesche HU. Kidney-transplant rejection and anti-MICA antibodies. N Engl J Med. 2008;358:196; author reply 196.
41. Riemekasten G, Philippe A, Nather M, Slowinski T, Muller DN, Heidecke H, Matucci-Cerinic M, Czirjak L, Lukitsch I, Becker M, Kill A, van Laar JM, Catar R, Luft FC, Burmester GR, Hegner B, Dragun D. Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis. 2011;70:530-536.
42. Schofield CJ, Ratcliffe PJ. Signalling hypoxia by HIF hydroxylases. Biochem Biophys Res Commun. 2005;338:617-626. (Pubitemid 41541972)
43. Burton GJ, Woods AW, Jauniaux E, Kingdom JC. Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy. Placenta. 2009; 30:473-482.
44. Liu Q, Berchner-Pfannschmidt U, Moller U, Brecht M, Wotzlaw C, Acker H, Jungermann K, Kietzmann T. A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression. Proc Natl Acad Sci USA. 2004;101:4302-4307. (Pubitemid 38405924)
45. Giordano FJ. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest. 2005;115:500-508. (Pubitemid 40322219)
46. Roberts L, LaMarca BB, Fournier L, Bain J, Cockrell K, Granger JP. Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusion. Hypertension. 2006;47: 615-618. (Pubitemid 43843885)