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Volumn 177, Issue 6, 2010, Pages 2950-2962

Effects of hypoxia-inducible factor-1α overexpression in pregnant mice: Possible implications for preeclampsia and intrauterine growth restriction

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALBUMIN; CREATININE; ENDOGLIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIVER ENZYME; LUCIFERASE; VASCULOTROPIN RECEPTOR 1;

EID: 78650222706     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090800     Document Type: Article
Times cited : (123)

References (50)
  • 2
    • 33745272281 scopus 로고    scopus 로고
    • Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia
    • DOI 10.1016/j.ajog.2005.07.049, PII S0002937805011336
    • Ness RB, Sibai BM: Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am J Obstet Gynecol 2006, 195:40-49 (Pubitemid 43927490)
    • (2006) American Journal of Obstetrics and Gynecology , vol.195 , Issue.1 , pp. 40-49
    • Ness, R.B.1    Sibai, B.M.2
  • 3
    • 0038113155 scopus 로고    scopus 로고
    • Endovascular trophoblast invasion: Implications for the pathogenesis of intrauterine growth retardation and preeclampsia
    • Kaufmann P, Black S, Huppertz B: Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod 2003, 69:1-7
    • (2003) Biol Reprod , vol.69 , pp. 1-7
    • Kaufmann, P.1    Black, S.2    Huppertz, B.3
  • 4
    • 20444409135 scopus 로고    scopus 로고
    • Latest advances in understanding preeclampsia
    • Redman CW, Sargent IL: Latest advances in understanding preeclampsia. Science 2005, 308:1592-1594
    • (2005) Science , vol.308 , pp. 1592-1594
    • Redman, C.W.1    Sargent, I.L.2
  • 5
    • 0030935503 scopus 로고    scopus 로고
    • Placental cytokines and the pathogenesis of preeclampsia
    • Conrad KP, Benyo DF: Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol 1997, 37:240-249
    • (1997) Am J Reprod Immunol , vol.37 , pp. 240-249
    • Conrad, K.P.1    Benyo, D.F.2
  • 8
    • 33846267013 scopus 로고    scopus 로고
    • Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction
    • Lond
    • Wallner W, Sengenberger R, Strick R, Strissel PL, Meurer B, Beckmann MW, Schlembach D: Angiogenic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. Clin Sci (Lond) 2007, 112:51-57
    • (2007) Clin Sci , vol.112 , pp. 51-57
    • Wallner, W.1    Sengenberger, R.2    Strick, R.3    Strissel, P.L.4    Meurer, B.5    Beckmann, M.W.6    Schlembach, D.7
  • 9
    • 38349087878 scopus 로고    scopus 로고
    • Circulatory soluble endoglin and its predictive value for preeclampsia in second-trimester pregnancies with abnormal uterine perfusion
    • e171-176
    • Stepan H, Geipel A, Schwarz F, Kramer T, Wessel N, Faber R: Circulatory soluble endoglin and its predictive value for preeclampsia in second-trimester pregnancies with abnormal uterine perfusion, Am J Obstet Gynecol 2008, 198:175 e171-176
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 175
    • Stepan, H.1    Geipel, A.2    Schwarz, F.3    Kramer, T.4    Wessel, N.5    Faber, R.6
  • 10
    • 37849021866 scopus 로고    scopus 로고
    • A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate
    • Romero R, Nien JK, Espinoza J, Todem D, Fu W, Chung H, Kusanovic JP, Gotsch F, Erez O, Mazaki-Tovi S, Gomez R, Edwin S, Chaiworapongsa T, Levine RJ, Karumanchi SA: A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. J Matern Fetal Neonatal Med 2008, 21:9-23
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 9-23
    • Romero, R.1    Nien, J.K.2    Espinoza, J.3    Todem, D.4    Fu, W.5    Chung, H.6    Kusanovic, J.P.7    Gotsch, F.8    Erez, O.9    Mazaki-Tovi, S.10    Gomez, R.11    Edwin, S.12    Chaiworapongsa, T.13    Levine, R.J.14    Karumanchi, S.A.15
  • 14
    • 59849106572 scopus 로고    scopus 로고
    • Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression
    • Gilbert JS, Gilbert SA, Arany M, Granger JP: Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression. Hypertension 2009, 53:399-403
    • (2009) Hypertension , vol.53 , pp. 399-403
    • Gilbert, J.S.1    Gilbert, S.A.2    Arany, M.3    Granger, J.P.4
  • 15
    • 36448996940 scopus 로고    scopus 로고
    • Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression
    • Gilbert JS, Babcock SA, Granger JP: Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression. Hypertension 2007, 50:1142-1147
    • (2007) Hypertension , vol.50 , pp. 1142-1147
    • Gilbert, J.S.1    Babcock, S.A.2    Granger, J.P.3
  • 16
    • 0033873636 scopus 로고    scopus 로고
    • Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta
    • Rajakumar A, Conrad KP: Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biol Reprod 2000, 63:559-569 (Pubitemid 30639947)
    • (2000) Biology of Reproduction , vol.63 , Issue.2 , pp. 559-569
    • Rajakumar, A.1    Conrad, K.P.2
  • 18
    • 4644281668 scopus 로고    scopus 로고
    • Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae
    • DOI 10.1016/j.placenta.2004.02.011, PII S0143400404000797
    • Rajakumar A, Brandon HM, Daftary A, Ness R, Conrad KP: Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae. Placenta 2004, 25:763-769 (Pubitemid 39276941)
    • (2004) Placenta , vol.25 , Issue.10 , pp. 763-769
    • Rajakumar, A.1    Brandon, H.M.2    Daftary, A.3    Ness, R.4    Conrad, K.P.5
  • 19
    • 10644283807 scopus 로고    scopus 로고
    • Adriana and Luisa Castellucci Award Lecture 2001. Hypoxia inducible factor-1: Oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies - A review
    • Caniggia I, Winter JL: Adriana and Luisa Castellucci Award Lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies - a review. Placenta 2002, 23(Suppl A):S47-S57
    • (2002) Placenta , vol.23 , Issue.SUPPL. A
    • Caniggia, I.1    Winter, J.L.2
  • 20
    • 38149017731 scopus 로고    scopus 로고
    • Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies
    • Gu Y, Lewis DF, Wang Y: Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies. J Clin Endocrinol Metab 2008, 93:260-266
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 260-266
    • Gu, Y.1    Lewis, D.F.2    Wang, Y.3
  • 21
    • 43849113456 scopus 로고    scopus 로고
    • Circulating and placental endoglin concentrations in pregnancies complicated by intrauterine growth restriction and preeclampsia
    • Jeyabalan A, McGonigal S, Gilmour C, Hubel CA, Rajakumar A: Circulating and placental endoglin concentrations in pregnancies complicated by intrauterine growth restriction and preeclampsia. Placenta 2008, 29:555-563
    • (2008) Placenta , vol.29 , pp. 555-563
    • Jeyabalan, A.1    McGonigal, S.2    Gilmour, C.3    Hubel, C.A.4    Rajakumar, A.5
  • 22
    • 38149044089 scopus 로고    scopus 로고
    • Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction
    • Nevo O, Many A, Xu J, Kingdom J, Piccoli E, Zamudio S, Post M, Bocking A, Todros T, Caniggia I: Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction. J Clin Endocrinol Metab 2008, 93:285-292
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 285-292
    • Nevo, O.1    Many, A.2    Xu, J.3    Kingdom, J.4    Piccoli, E.5    Zamudio, S.6    Post, M.7    Bocking, A.8    Todros, T.9    Caniggia, I.10
  • 23
    • 38749144767 scopus 로고    scopus 로고
    • Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: Hypoxic regulation via transforming growth factor-β 3
    • Yinon Y, Nevo O, Xu J, Many A, Rolfo A, Todros T, Post M, Caniggia I: Severe intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-β 3. Am J Pathol 2008, 172:77-85
    • (2008) Am J Pathol , vol.172 , pp. 77-85
    • Yinon, Y.1    Nevo, O.2    Xu, J.3    Many, A.4    Rolfo, A.5    Todros, T.6    Post, M.7    Caniggia, I.8
  • 25
    • 0037113959 scopus 로고    scopus 로고
    • Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways
    • DOI 10.1074/jbc.M207160200
    • Sánchez-Elsner T, Botella LM, Velasco B, Langa C, Bernabeu C: Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem 2002, 277:43799-43808 (Pubitemid 36157800)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.46 , pp. 43799-43808
    • Sanchez-Elsner, T.1    Botella, L.M.2    Velasco, B.3    Langa, C.4    Bernabeu, C.5
  • 26
    • 34447303822 scopus 로고    scopus 로고
    • Human placental hypoxia-inducible factor-1α expression correlates with clinical outcomes in chronic hypoxia in vivo
    • Zamudio S, Wu Y, Ietta F, Rolfo A, Cross A, Wheeler T, Post M, Illsley NP, Caniggia I: Human placental hypoxia-inducible factor-1α expression correlates with clinical outcomes in chronic hypoxia in vivo. Am J Pathol 2007, 170:2171-2179
    • (2007) Am J Pathol , vol.170 , pp. 2171-2179
    • Zamudio, S.1    Wu, Y.2    Ietta, F.3    Rolfo, A.4    Cross, A.5    Wheeler, T.6    Post, M.7    Illsley, N.P.8    Caniggia, I.9
  • 28
    • 45449089835 scopus 로고    scopus 로고
    • Activation of C-transactivation domain is essential for optimal HIF-1α-mediated transcriptional and angiogenic effects
    • Tal R, Shaish A, Bangio L, Peled M, Breitbart E, Harats D: Activation of C-transactivation domain is essential for optimal HIF-1α-mediated transcriptional and angiogenic effects. Microvasc Res 2008, 76:1-6
    • (2008) Microvasc Res , vol.76 , pp. 1-6
    • Tal, R.1    Shaish, A.2    Bangio, L.3    Peled, M.4    Breitbart, E.5    Harats, D.6
  • 31
    • 0028915634 scopus 로고
    • The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants
    • Huard J, Lochmuller H, Acsadi G, Jani A, Massie B, Karpati G: The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants. Gene Ther 1995, 2:107-115
    • (1995) Gene Ther , vol.2 , pp. 107-115
    • Huard, J.1    Lochmuller, H.2    Acsadi, G.3    Jani, A.4    Massie, B.5    Karpati, G.6
  • 32
    • 0036399622 scopus 로고    scopus 로고
    • Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta
    • Adamson SL, Lu Y, Whiteley KJ, Holmyard D, Hemberger M, Pfarrer C, Cross JC: Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta. Dev Biol 2002, 250:358-373
    • (2002) Dev Biol , vol.250 , pp. 358-373
    • Adamson, S.L.1    Lu, Y.2    Whiteley, K.J.3    Holmyard, D.4    Hemberger, M.5    Pfarrer, C.6    Cross, J.C.7
  • 34
    • 85052978487 scopus 로고    scopus 로고
    • Syndrome of hemolysis, elevated liver enzymes, and low platelet count: A severe consequence of hypertension in pregnancy. 1982
    • discussion 860
    • Weinstein L: Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy. 1982. Am J Obstet Gynecol 2005, 193:859; discussion 860
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 859
    • Weinstein, L.1
  • 35
    • 0026729855 scopus 로고
    • Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count)
    • Barton JR, Riely CA, Adamec TA, Shanklin DR, Khoury AD, Sibai BM: Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). Am J Obstet Gynecol 1992, 167:1538-1543
    • (1992) Am J Obstet Gynecol , vol.167 , pp. 1538-1543
    • Barton, J.R.1    Riely, C.A.2    Adamec, T.A.3    Shanklin, D.R.4    Khoury, A.D.5    Sibai, B.M.6
  • 38
    • 49149095044 scopus 로고    scopus 로고
    • Putting pressure on pre-eclampsia
    • Parikh SM, Karumanchi SA: Putting pressure on pre-eclampsia. Nat Med 2008, 14:810-812
    • (2008) Nat Med , vol.14 , pp. 810-812
    • Parikh, S.M.1    Karumanchi, S.A.2
  • 40
    • 76149146741 scopus 로고    scopus 로고
    • Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions
    • Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R: Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions, Am J Pathol 176:710-720
    • Am J Pathol , vol.176 , pp. 710-720
    • Lee, S.B.1    Wong, A.P.2    Kanasaki, K.3    Xu, Y.4    Shenoy, V.K.5    McElrath, T.F.6    Whitesides, G.M.7    Kalluri, R.8
  • 41
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α
    • Elson DA, Thurston G, Huang LE, Ginzinger DG, McDonald DM, Johnson RS, Arbeit JM: Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α. Genes Dev 2001, 15:2520-2532
    • (2001) Genes Dev , vol.15 , pp. 2520-2532
    • Elson, D.A.1    Thurston, G.2    Huang, L.E.3    Ginzinger, D.G.4    McDonald, D.M.5    Johnson, R.S.6    Arbeit, J.M.7
  • 42
    • 18644376701 scopus 로고    scopus 로고
    • In utero angiopoietin-2 gene delivery remodels placental blood vessel phenotype: A murine model for studying placental angiogenesis
    • Geva E, Ginzinger DG, Moore DH, 2nd, Ursell PC, Jaffe RB: In utero angiopoietin-2 gene delivery remodels placental blood vessel phenotype: a murine model for studying placental angiogenesis. Mol Hum Reprod 2005, 11:253-260
    • (2005) Mol Hum Reprod , vol.11 , pp. 253-260
    • Geva, E.1    Ginzinger, D.G.2    Moore II, D.H.3    Ursell, P.C.4    Jaffe, R.B.5
  • 45
    • 33947619480 scopus 로고    scopus 로고
    • The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice
    • discussion 396.e7
    • Lu F, Longo M, Tamayo E, Maner W, Al-Hendy A, Anderson GD, Hankins GD, Saade GR: The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice, Am J Obstet Gynecol 2007, 196:396.e1-396.e7; discussion 396.e7
    • (2007) Am J Obstet Gynecol , vol.196
    • Lu, F.1    Longo, M.2    Tamayo, E.3    Maner, W.4    Al-Hendy, A.5    Anderson, G.D.6    Hankins, G.D.7    Saade, G.R.8
  • 47
    • 0027243395 scopus 로고
    • HELLP syndrome-like biochemical parameters obtained with endothelin-1 injections in rabbits
    • Halim A, Kanayama N, Maehara K, Takahashi M, Terao T: HELLP syndrome-like biochemical parameters obtained with endothelin-1 injections in rabbits. Gynecol Obstet Invest 1993, 35:193-198
    • (1993) Gynecol Obstet Invest , vol.35 , pp. 193-198
    • Halim, A.1    Kanayama, N.2    Maehara, K.3    Takahashi, M.4    Terao, T.5
  • 48
    • 0035918213 scopus 로고    scopus 로고
    • Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP
    • Yamashita K, Discher DJ, Hu J, Bishopric NH, Webster KA: Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, and p300/CBP. J Biol Chem 2001, 276:12645-12653
    • (2001) J Biol Chem , vol.276 , pp. 12645-12653
    • Yamashita, K.1    Discher, D.J.2    Hu, J.3    Bishopric, N.H.4    Webster, K.A.5
  • 49
    • 0032576971 scopus 로고    scopus 로고
    • Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand
    • Hu J, Discher DJ, Bishopric NH, Webster KA: Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand. Biochem Biophys Res Commun 1998, 245:894-899
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 894-899
    • Hu, J.1    Discher, D.J.2    Bishopric, N.H.3    Webster, K.A.4
  • 50
    • 0033936370 scopus 로고    scopus 로고
    • Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: Role of hypoxia responsive element
    • Minchenko A, Caro J: Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element. Mol Cell Biochem 2000, 208:53-62
    • (2000) Mol Cell Biochem , vol.208 , pp. 53-62
    • Minchenko, A.1    Caro, J.2


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