-
1
-
-
0017643758
-
Unconventional viruses and the origin and disappearance of kuru
-
Gajdusek, D. C. Unconventional viruses and the origin and disappearance of kuru. Science197 (1977) 943-960.
-
(1977)
Science
, vol.197
, pp. 943-960
-
-
Gajdusek, D.C.1
-
2
-
-
0024262335
-
Molecular structure, biology, and genetics of prions
-
Prusiner, S. B. Molecular structure, biology, and genetics of prions. Adv. Virus. Res. 35 (1988) 83-136.
-
(1988)
Adv. Virus. Res.
, vol.35
, pp. 83-136
-
-
Prusiner, S.B.1
-
3
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
Pan, K. M., Baldwin, M., Nguyen, J., Gasset, M., Serban, A., Groth, D., Mehlhorn, I., Huang, Z., Fletterick, R. J. and Cohen, F. E. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA90 (1993) 10962-10966.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
-
4
-
-
74249084312
-
De novo mammalian prion synthesis
-
Benetti, F. and Legname, G. De novo mammalian prion synthesis. Prion3 (2009) 213-219.
-
(2009)
Prion
, vol.3
, pp. 213-219
-
-
Benetti, F.1
Legname, G.2
-
5
-
-
0028338441
-
Structural clues to prion replication
-
Cohen, F. E., Pan, K. M., Huang, Z., Baldwin, M., Fletterick, R. J. and Prusiner, S. B. Structural clues to prion replication. Science264 (1994) 530-531.
-
(1994)
Science
, vol.264
, pp. 530-531
-
-
Cohen, F.E.1
Pan, K.M.2
Huang, Z.3
Baldwin, M.4
Fletterick, R.J.5
Prusiner, S.B.6
-
6
-
-
0021752457
-
Purification and structural studies of a major scrapie prion protein
-
Prusiner, S. B., Groth, D. F., Bolton, D. C., Kent, S. B. and Hood, L. E. Purification and structural studies of a major scrapie prion protein. Cell38 (1984) 127-134.
-
(1984)
Cell
, vol.38
, pp. 127-134
-
-
Prusiner, S.B.1
Groth, D.F.2
Bolton, D.C.3
Kent, S.B.4
Hood, L.E.5
-
7
-
-
0022005315
-
A cellular gene encodes scrapie PrP 27-30 protein
-
Oesch, B., Westaway, D., Wälchli, M., McKinley, M. P., Kent, S. B., Aebersold, R., Barry, R. A., Tempst, P., Teplow, D. B., Hood, L. E., Prusiner, S. B. and Weissmann, C. A cellular gene encodes scrapie PrP 27-30 protein. Cell40 (1985) 735-746.
-
(1985)
Cell
, vol.40
, pp. 735-746
-
-
Oesch, B.1
Westaway, D.2
Wälchli, M.3
McKinley, M.P.4
Kent, S.B.5
Aebersold, R.6
Barry, R.A.7
Tempst, P.8
Teplow, D.B.9
Hood, L.E.10
Prusiner, S.B.11
Weissmann, C.12
-
8
-
-
0026757763
-
Molecular cloning of a candidate chicken prion protein
-
Gabriel, J. M., Oesch, B., Kretzschmar, H., Scott, M. and Prusiner, S. B. Molecular cloning of a candidate chicken prion protein. Proc. Natl. Acad. Sci. USA89 (1992) 9097-9101.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9097-9101
-
-
Gabriel, J.M.1
Oesch, B.2
Kretzschmar, H.3
Scott, M.4
Prusiner, S.B.5
-
9
-
-
0028962532
-
Prion protein gene variation among primates
-
Schatzl, H. M., Da Costa, M., Taylor, L., Cohen, F. E. and Prusiner, S. B. Prion protein gene variation among primates. J. Mol. Biol. 245 (1995) 362-374.
-
(1995)
J. Mol. Biol.
, vol.245
, pp. 362-374
-
-
Schatzl, H.M.1
Da Costa, M.2
Taylor, L.3
Cohen, F.E.4
Prusiner, S.B.5
-
10
-
-
0022476747
-
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
-
Basler, K., Oesch, B., Scott, M., Westaway, D., Wälchli, M., Groth, D. F., McKinley, M. P., Prusiner, S. B. and Weissmann, C. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell46 (1986) 417-428.
-
(1986)
Cell
, vol.46
, pp. 417-428
-
-
Basler, K.1
Oesch, B.2
Scott, M.3
Westaway, D.4
Wälchli, M.5
Groth, D.F.6
McKinley, M.P.7
Prusiner, S.B.8
Weissmann, C.9
-
11
-
-
0022569404
-
Scrapie prion proteins are synthesized in neurons
-
Kretzschmar, H. A., Prusiner, S. B., Stowring, L. E. and DeArmond, S. J. Scrapie prion proteins are synthesized in neurons. Am. J. Pathol. 122 (1986) 1-5.
-
(1986)
Am. J. Pathol.
, vol.122
, pp. 1-5
-
-
Kretzschmar, H.A.1
Prusiner, S.B.2
Stowring, L.E.3
DeArmond, S.J.4
-
12
-
-
0033515029
-
Copper binding to the prion protein: structural implications of four identical cooperative binding sites
-
Viles, J. H., Cohen, F. E., Prusiner, S. B., Goodin, D. B., Wright, P. E. and Dyson, H. J. Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proc. Natl. Acad. Sci. USA96 (1999) 2042-2047.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2042-2047
-
-
Viles, J.H.1
Cohen, F.E.2
Prusiner, S.B.3
Goodin, D.B.4
Wright, P.E.5
Dyson, H.J.6
-
13
-
-
0012710491
-
NMR solution structure of the human prion protein
-
Zahn, R., Liu, A., Luhrs, T., Riek, R., von Schroetter, C., Garcia, F. L., Billeter, M., Calzolai, L., Wider, G. and Wüthrich, K. NMR solution structure of the human prion protein. Proc. Natl. Acad. Sci. USA97 (2000) 145-150.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 145-150
-
-
Zahn, R.1
Liu, A.2
Luhrs, T.3
Riek, R.4
von Schroetter, C.5
Garcia, F.L.6
Billeter, M.7
Calzolai, L.8
Wider, G.9
Wüthrich, K.10
-
14
-
-
0025091084
-
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein
-
Stahl, N., Baldwin, M. A., Burlingame, A. L. and Prusiner, S. B. Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein. Biochemistry29 (1990) 8879-8884.
-
(1990)
Biochemistry
, vol.29
, pp. 8879-8884
-
-
Stahl, N.1
Baldwin, M.A.2
Burlingame, A.L.3
Prusiner, S.B.4
-
15
-
-
0029962468
-
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
-
Vey, M., Pilkuhn, S., Wille, H., Nixon, R., DeArmond, S. J., Smart, E. J., Anderson, R. G. W., Taraboulos, A. and Prusiner, S. B. Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc. Natl. Acad. Sci. USA93 (1996) 14945-14949.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14945-14949
-
-
Vey, M.1
Pilkuhn, S.2
Wille, H.3
Nixon, R.4
DeArmond, S.J.5
Smart, E.J.6
Anderson, R.G.W.7
Taraboulos, A.8
Prusiner, S.B.9
-
16
-
-
0030894380
-
Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform
-
Naslavsky, N., Stein, R., Yanai, A., Friedlander, G. and Taraboulos, A. Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J. Biol. Chem. 272 (1997) 6324-6331.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6324-6331
-
-
Naslavsky, N.1
Stein, R.2
Yanai, A.3
Friedlander, G.4
Taraboulos, A.5
-
17
-
-
0027204276
-
A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells
-
Shyng, S. L., Huber, M. T. and Harris, D. A. A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells. J. Biol. Chem. 268 (1993) 15922-15928.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15922-15928
-
-
Shyng, S.L.1
Huber, M.T.2
Harris, D.A.3
-
18
-
-
0031692336
-
The caveolae membrane system
-
Anderson, R. G. The caveolae membrane system. Annu. Rev. Biochem. 67 (1998) 199-225.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 199-225
-
-
Anderson, R.G.1
-
19
-
-
33645290776
-
The prion protein and lipid rafts
-
Taylor, D. R. and Hooper, N. M. The prion protein and lipid rafts. Mol. Membr. Biol. 23 (2006) 89-99.
-
(2006)
Mol. Membr. Biol.
, vol.23
, pp. 89-99
-
-
Taylor, D.R.1
Hooper, N.M.2
-
20
-
-
0026775909
-
Evidence for synthesis of scrapie prion proteins in the endocytic pathway
-
Borchelt, D. R., Taraboulos, A. and Prusiner, S. B. Evidence for synthesis of scrapie prion proteins in the endocytic pathway. J. Biol. Chem. 267 (1992) 16188-16199.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16188-16199
-
-
Borchelt, D.R.1
Taraboulos, A.2
Prusiner, S.B.3
-
21
-
-
79952795300
-
Infrared microspectroscopy: a multiple-screening platform for investigating singlecell biochemical perturbations upon prion infection
-
Didonna, A., Vaccari, L., Bek, A. and Legname, G. Infrared microspectroscopy: a multiple-screening platform for investigating singlecell biochemical perturbations upon prion infection. ACS Chem. Neurosci. 2 (2011) 160-174.
-
(2011)
ACS Chem. Neurosci.
, vol.2
, pp. 160-174
-
-
Didonna, A.1
Vaccari, L.2
Bek, A.3
Legname, G.4
-
22
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Bueler, H., Fischer, M., Lang, Y., Bluethmann, H., Lipp, H. P., DeArmond, S. J., Prusiner, S. B., Aguet, M. and Weissmann, C. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature356 (1992) 577-582.
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Bueler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.P.5
DeArmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
23
-
-
0028420937
-
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
-
Manson, J. C., Clarke, A. R., Hooper, M. L., Aitchison, L., McConnell, I. and Hope, J. 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol. Neurobiol. 8 (1994) 121-127.
-
(1994)
Mol. Neurobiol.
, vol.8
, pp. 121-127
-
-
Manson, J.C.1
Clarke, A.R.2
Hooper, M.L.3
Aitchison, L.4
McConnell, I.5
Hope, J.6
-
24
-
-
15844421385
-
Altered circadian activity rhythms and sleep in mice devoid of prion protein
-
Tobler, I., Gaus, S. E., Deboer, T., Achermann, P., Fischer, M., Rülicke, T., Moser, M., Oesch, B., McBride, P. A. and Manson, J. C. Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature380 (1996) 639-642.
-
(1996)
Nature
, vol.380
, pp. 639-642
-
-
Tobler, I.1
Gaus, S.E.2
Deboer, T.3
Achermann, P.4
Fischer, M.5
Rülicke, T.6
Moser, M.7
Oesch, B.8
McBride, P.A.9
Manson, J.C.10
-
25
-
-
0042200243
-
Cellular prion protein ablation impairs behavior as a function of age
-
Coitinho, A. S., Roesler, R., Martins, V. R., Brentani, R. R. and Izquierdo, I. Cellular prion protein ablation impairs behavior as a function of age. Neuroreport14 (2003) 1375-1379.
-
(2003)
Neuroreport
, vol.14
, pp. 1375-1379
-
-
Coitinho, A.S.1
Roesler, R.2
Martins, V.R.3
Brentani, R.R.4
Izquierdo, I.5
-
26
-
-
20244371991
-
Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons
-
Criado, J. R., Sánchez-Alavez, M., Conti, B., Giacchino, J. L., Wills, D. N., Henriksen, S. J., Race, R., Manson, J. C., Chesebro, B. and Oldstone, M. B. Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol. Dis. 19 (2005) 255-265.
-
(2005)
Neurobiol. Dis.
, vol.19
, pp. 255-265
-
-
Criado, J.R.1
Sánchez-Alavez, M.2
Conti, B.3
Giacchino, J.L.4
Wills, D.N.5
Henriksen, S.J.6
Race, R.7
Manson, J.C.8
Chesebro, B.9
Oldstone, M.B.10
-
27
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
Sakaguchi, S., Katamine, S., Nishida, N., Moriuchi, R., Shigematsu, K., Sugimoto, T., Nakatani, A., Kataoka, Y., Houtani, T., Shirabe, S., Okada, H., Hasegawa, S., Miyamoto, T. and Noda, T. Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature380 (1996) 528-531.
-
(1996)
Nature
, vol.380
, pp. 528-531
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
Moriuchi, R.4
Shigematsu, K.5
Sugimoto, T.6
Nakatani, A.7
Kataoka, Y.8
Houtani, T.9
Shirabe, S.10
Okada, H.11
Hasegawa, S.12
Miyamoto, T.13
Noda, T.14
-
28
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
Moore, R. C., Lee, I. Y., Silverman, G. L., Harrison, P. M., Strome, R., Heinrich, C., Karunaratne, A., Pasternak, S. H., Chishti, M. A., Liang, Y., Mastrangelo, P., Wang, K., Smit, A. F., Katamine, S., Carlson, G. A., Cohen, F. E., Prusiner, S. B., Melton, D. W., Tremblay, P., Hood, L. E. and Westaway, D. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J. Mol. Biol. 292 (1999) 797-817.
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 797-817
-
-
Moore, R.C.1
Lee, I.Y.2
Silverman, G.L.3
Harrison, P.M.4
Strome, R.5
Heinrich, C.6
Karunaratne, A.7
Pasternak, S.H.8
Chishti, M.A.9
Liang, Y.10
Mastrangelo, P.11
Wang, K.12
Smit, A.F.13
Katamine, S.14
Carlson, G.A.15
Cohen, F.E.16
Prusiner, S.B.17
Melton, D.W.18
Tremblay, P.19
Hood, L.E.20
Westaway, D.21
more..
-
29
-
-
84863714721
-
The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells
-
Didonna, A., Sussman, J., Benetti, F. and Legname, G. The role of Bax and caspase-3 in doppel-induced apoptosis of cerebellar granule cells. Prion6 (2012) 309-316.
-
(2012)
Prion
, vol.6
, pp. 309-316
-
-
Didonna, A.1
Sussman, J.2
Benetti, F.3
Legname, G.4
-
30
-
-
0036470471
-
Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
-
Mallucci, G. R., Ratte, S., Asante, E. A., Linehan, J., Gowland, I., Jefferys, J. G. and Collinge, J. Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. EMBO J. 21 (2002) 202-210.
-
(2002)
EMBO J.
, vol.21
, pp. 202-210
-
-
Mallucci, G.R.1
Ratte, S.2
Asante, E.A.3
Linehan, J.4
Gowland, I.5
Jefferys, J.G.6
Collinge, J.7
-
31
-
-
33846172709
-
Production of cattle lacking prion protein
-
Richt, J. A., Kasinathan, P., Hamir, A. N., Castilla, J., Sathiyaseelan, T., Vargas, F., Sathiyaseelan, J., Wu, H., Matsushita, H., Koster, J., Kato, S., Ishida, I., Soto, C., Robl, J. M. and Kuroiwa, Y. Production of cattle lacking prion protein. Nat. Biotechnol. 25 (2007) 132-138.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 132-138
-
-
Richt, J.A.1
Kasinathan, P.2
Hamir, A.N.3
Castilla, J.4
Sathiyaseelan, T.5
Vargas, F.6
Sathiyaseelan, J.7
Wu, H.8
Matsushita, H.9
Koster, J.10
Kato, S.11
Ishida, I.12
Soto, C.13
Robl, J.M.14
Kuroiwa, Y.15
-
32
-
-
58449100797
-
Generation of goats lacking prion protein
-
Yu, G., Chen, J., Xu, Y., Zhu, C., Yu, H., Liu, S., Sha, H., Chen, J., Xu, X., Wu, Y., Zhang, A., Ma, J. and Cheng, G. Generation of goats lacking prion protein. Mol. Reprod. Dev. 76 (2009) 3.
-
(2009)
Mol. Reprod. Dev.
, vol.76
, pp. 3
-
-
Yu, G.1
Chen, J.2
Xu, Y.3
Zhu, C.4
Yu, H.5
Liu, S.6
Sha, H.7
Chen, J.8
Xu, X.9
Wu, Y.10
Zhang, A.11
Ma, J.12
Cheng, G.13
-
33
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Bueler, H., Aguzzi, A., Sailer, A., Greiner, R. A., Autenried, P., Aguet, M. and Weissmann, C. Mice devoid of PrP are resistant to scrapie. Cell73 (1993) 1339-1347.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Bueler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
Aguet, M.6
Weissmann, C.7
-
34
-
-
65949115708
-
Regulation of embryonic cell adhesion by the prion protein
-
Malaga-Trillo, E., Solis, G. P., Schrock, Y., Geiss, C., Luncz, L., Thomanetz, V. and Stuermer, C. A. Regulation of embryonic cell adhesion by the prion protein. PLOS Biol. 7 (2009) e55.
-
(2009)
PLOS Biol.
, vol.7
-
-
Malaga-Trillo, E.1
Solis, G.P.2
Schrock, Y.3
Geiss, C.4
Luncz, L.5
Thomanetz, V.6
Stuermer, C.A.7
-
35
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown, D. R., Qin, K., Herms, J. W., Madlung, A., Manson, J., Strome, R., Fraser, P. E., Kruck, T., von Bohlen, A., Schulz-Schaeffer, W., Giese, A., Westaway, D. and Kretzschmar, H. The cellular prion protein binds copper in vivo. Nature390 (1997) 684-687.
-
(1997)
Nature
, vol.390
, pp. 684-687
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
Madlung, A.4
Manson, J.5
Strome, R.6
Fraser, P.E.7
Kruck, T.8
von Bohlen, A.9
Schulz-Schaeffer, W.10
Giese, A.11
Westaway, D.12
Kretzschmar, H.13
-
36
-
-
0035158321
-
Antioxidant activity related to copper binding of native prion protein
-
Brown, D. R., Clive, C. and Haswell, S. J. Antioxidant activity related to copper binding of native prion protein. J. Neurochem. 76 (2001) 69-76.
-
(2001)
J. Neurochem.
, vol.76
, pp. 69-76
-
-
Brown, D.R.1
Clive, C.2
Haswell, S.J.3
-
37
-
-
0031047646
-
Sleep and sleep regulation in normal and prion protein-deficient mice
-
Tobler, I., Deboer, T. and Fischer, M. Sleep and sleep regulation in normal and prion protein-deficient mice. J. Neurosci. 17 (1997) 1869-1879.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1869-1879
-
-
Tobler, I.1
Deboer, T.2
Fischer, M.3
-
38
-
-
58149108891
-
Olfactory behavior and physiology are disrupted in prion protein knockout mice
-
Le Pichon, C. E., Valley, M. T., Polymenidou, M., Chesler, A. T., Sagdullaev, B. T., Aguzzi, A. and Firestein, S. Olfactory behavior and physiology are disrupted in prion protein knockout mice. Nat. Neurosci. 12 (2009) 60-69.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 60-69
-
-
Le Pichon, C.E.1
Valley, M.T.2
Polymenidou, M.3
Chesler, A.T.4
Sagdullaev, B.T.5
Aguzzi, A.6
Firestein, S.7
-
39
-
-
77649091387
-
Axonal prion protein is required for peripheral myelin maintenance
-
Bremer, J., Baumann, F., Tiberi, C., Wessig, C., Fischer, H., Schwarz, P., Steele, A. D., Toyka, K. V., Nave, K. A., Weis, J. and Aguzzi, A. Axonal prion protein is required for peripheral myelin maintenance. Nat. Neurosci. 13 (2010) 310-318.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 310-318
-
-
Bremer, J.1
Baumann, F.2
Tiberi, C.3
Wessig, C.4
Fischer, H.5
Schwarz, P.6
Steele, A.D.7
Toyka, K.V.8
Nave, K.A.9
Weis, J.10
Aguzzi, A.11
-
40
-
-
33144456321
-
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal
-
Zhang, C. C., Steele, A. D., Lindquist, S. and Lodish, H. F. Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc. Natl. Acad. Sci. USA103 (2006) 2184-2189.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2184-2189
-
-
Zhang, C.C.1
Steele, A.D.2
Lindquist, S.3
Lodish, H.F.4
-
41
-
-
33748713915
-
The role of the cellular prion protein in the immune system
-
Isaacs, J. D., Jackson, G. S. and Altmann, D. M. The role of the cellular prion protein in the immune system. Clin. Exp. Immunol. 146 (2006) 1-8.
-
(2006)
Clin. Exp. Immunol.
, vol.146
, pp. 1-8
-
-
Isaacs, J.D.1
Jackson, G.S.2
Altmann, D.M.3
-
42
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
Shmerling, D., Hegyi, I., Fischer, M., Blättler, T., Brandner, S., Götz, J., Rülicke, T., Flechsig, E., Cozzio, A., von Mering, C., Hangartner, C., Aguzzi, A. and Weissmann, C. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell93 (1998) 203-214.
-
(1998)
Cell
, vol.93
, pp. 203-214
-
-
Shmerling, D.1
Hegyi, I.2
Fischer, M.3
Blättler, T.4
Brandner, S.5
Götz, J.6
Rülicke, T.7
Flechsig, E.8
Cozzio, A.9
von Mering, C.10
Hangartner, C.11
Aguzzi, A.12
Weissmann, C.13
-
44
-
-
0028859279
-
Protein modules and signalling networks
-
Pawson, T. Protein modules and signalling networks. Nature373 (1995) 573-580.
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
46
-
-
0035861987
-
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein
-
Schmitt-Ulms, G., Legname, G., Baldwin, M. A., Ball, H. L., Bradon, N., Bosque, P. J., Crossin, K. L., Edelman, G. M., DeArmond, S. J., Cohen, F. E. and Prusiner, S. B. Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J. Mol. Biol. 314 (2001) 1209-1225.
-
(2001)
J. Mol. Biol.
, vol.314
, pp. 1209-1225
-
-
Schmitt-Ulms, G.1
Legname, G.2
Baldwin, M.A.3
Ball, H.L.4
Bradon, N.5
Bosque, P.J.6
Crossin, K.L.7
Edelman, G.M.8
DeArmond, S.J.9
Cohen, F.E.10
Prusiner, S.B.11
-
47
-
-
17944363361
-
The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein
-
Gauczynski, S., Peyrin, J. M., Haïk, S., Leucht, C., Hundt, C., Rieger, R., Krasemann, S., Deslys, J. P., Dormont, D., Lasmézas, C. I. and Weiss, S. The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein. EMBO J. 20 (2001) 5863-5875.
-
(2001)
EMBO J.
, vol.20
, pp. 5863-5875
-
-
Gauczynski, S.1
Peyrin, J.M.2
Haïk, S.3
Leucht, C.4
Hundt, C.5
Rieger, R.6
Krasemann, S.7
Deslys, J.P.8
Dormont, D.9
Lasmézas, C.I.10
Weiss, S.11
-
48
-
-
0034628999
-
Cellular prion protein binds laminin and mediates neuritogenesis
-
Graner, E., Mercadante, A. F., Zanata, S. M., Forlenza, O. V., Cabral, A. L., Veiga, S. S., Juliano, M. A., Roesler, R., Walz, R., Minetti, A., Izquierdo, I., Martins, V. R. and Brentani, R. R. Cellular prion protein binds laminin and mediates neuritogenesis. Brain Res. Mol. Brain Res. 76 (2000) 85-92.
-
(2000)
Brain Res. Mol. Brain Res.
, vol.76
, pp. 85-92
-
-
Graner, E.1
Mercadante, A.F.2
Zanata, S.M.3
Forlenza, O.V.4
Cabral, A.L.5
Veiga, S.S.6
Juliano, M.A.7
Roesler, R.8
Walz, R.9
Minetti, A.10
Izquierdo, I.11
Martins, V.R.12
Brentani, R.R.13
-
49
-
-
0031466157
-
Complementary hydropathy identifies a cellular prion protein receptor
-
Martins, V. R., Graner, E., Garcia-Abreu, J., de Souza, S. J., Mercadante, A. F., Veiga, S. S., Zanata, S. M., Neto, V. M. and Brentani, R. R. Complementary hydropathy identifies a cellular prion protein receptor. Nat. Med. 3 (1997) 1376-1382.
-
(1997)
Nat. Med.
, vol.3
, pp. 1376-1382
-
-
Martins, V.R.1
Graner, E.2
Garcia-Abreu, J.3
de Souza, S.J.4
Mercadante, A.F.5
Veiga, S.S.6
Zanata, S.M.7
Neto, V.M.8
Brentani, R.R.9
-
50
-
-
18444397736
-
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
-
Zanata, S. M., Lopes, M. H., Mercadante, A. F., Hajj, G. N. M., Chiarini, L. B., Nomizo, R., Freitas, A. R. O., Cabral, A. L. B., Lee, K. S., Juliano, M. A., de Oliveira, E., Jachieri, S. G., Burlingame, A., Huang, L., Linden, R., Brentani, R. R. and Martins, V. R. Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J. 21 (2002) 3307-3316.
-
(2002)
EMBO J.
, vol.21
, pp. 3307-3316
-
-
Zanata, S.M.1
Lopes, M.H.2
Mercadante, A.F.3
Hajj, G.N.M.4
Chiarini, L.B.5
Nomizo, R.6
Freitas, A.R.O.7
Cabral, A.L.B.8
Lee, K.S.9
Juliano, M.A.10
de Oliveira, E.11
Jachieri, S.G.12
Burlingame, A.13
Huang, L.14
Linden, R.15
Brentani, R.R.16
Martins, V.R.17
-
51
-
-
84887212358
-
The comprehensive native interactome of a fully functional tagged prion protein
-
Rutishauser, D., Mertz, K. D., Moos, R., Brunner, E., Rulicke, T., Calella, A. M. and Aguzzi, A. The comprehensive native interactome of a fully functional tagged prion protein. PLOS One4 (2009) e4446.
-
(2009)
PLOS One
, vol.4
-
-
Rutishauser, D.1
Mertz, K.D.2
Moos, R.3
Brunner, E.4
Rulicke, T.5
Calella, A.M.6
Aguzzi, A.7
-
52
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
-
Lauren, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W. and Strittmatter, S. M. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature457 (2009) 1128-1132.
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
53
-
-
77955617917
-
The prion protein as a receptor for amyloid-beta
-
Kessels, H. W., Nguyen, L. N., Nabavi, S. and Malinow, R. The prion protein as a receptor for amyloid-beta. Nature466 (2010) E3-4; discussion E4-5.
-
(2010)
Nature
, vol.466
-
-
Kessels, H.W.1
Nguyen, L.N.2
Nabavi, S.3
Malinow, R.4
-
54
-
-
76649093635
-
Synthetic amyloid-beta oligomers impair longterm memory independently of cellular prion protein
-
Balducci, C., Beeg, M., Stravalaci, M., Bastone, A., Sclip, A., Biasini, E., Tapella, L., Colombo, L., Manzoni, C., Borsello, T., Chiesa, R., Gobbi, M., Salmona, M. and Forloni, G. Synthetic amyloid-beta oligomers impair longterm memory independently of cellular prion protein. Proc. Natl. Acad. Sci. USA107 (2010) 2295-2300.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2295-2300
-
-
Balducci, C.1
Beeg, M.2
Stravalaci, M.3
Bastone, A.4
Sclip, A.5
Biasini, E.6
Tapella, L.7
Colombo, L.8
Manzoni, C.9
Borsello, T.10
Chiesa, R.11
Gobbi, M.12
Salmona, M.13
Forloni, G.14
-
55
-
-
77956165325
-
Prion protein and Abeta-related synaptic toxicity impairment
-
Calella, A. M., Farinelli, M., Nuvolone, M., Mirante, O., Moos, R., Falsig, J., Mansuy, I. M. and Aguzzi, A. Prion protein and Abeta-related synaptic toxicity impairment. EMBO Mol. Med. 2 (2010) 306-314.
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 306-314
-
-
Calella, A.M.1
Farinelli, M.2
Nuvolone, M.3
Mirante, O.4
Moos, R.5
Falsig, J.6
Mansuy, I.M.7
Aguzzi, A.8
-
56
-
-
0034665847
-
Signal transduction through prion protein
-
Mouillet-Richard, S., Ermonval, M., Chebassier, C., Laplanche, J. L., Lehmann, S., Launay, J. M. and Kellermann, O. Signal transduction through prion protein. Science289 (2000) 1925-1928.
-
(2000)
Science
, vol.289
, pp. 1925-1928
-
-
Mouillet-Richard, S.1
Ermonval, M.2
Chebassier, C.3
Laplanche, J.L.4
Lehmann, S.5
Launay, J.M.6
Kellermann, O.7
-
57
-
-
2942618768
-
A renaissance for SRC
-
Yeatman, T. J. A renaissance for SRC. Nat. Rev. Cancer4 (2004) 470-480.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 470-480
-
-
Yeatman, T.J.1
-
58
-
-
0027971705
-
NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice
-
Beggs, H. E., Soriano, P. and Maness, P. F. NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice. J. Cell Biol. 127 (1994) 825-833.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 825-833
-
-
Beggs, H.E.1
Soriano, P.2
Maness, P.F.3
-
59
-
-
18544376071
-
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth
-
Santuccione, A., Sytnyk, V., Leshchyns'ka, I. and Schachner, M. Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. J. Cell Biol. 169 (2005) 341-354.
-
(2005)
J. Cell Biol.
, vol.169
, pp. 341-354
-
-
Santuccione, A.1
Sytnyk, V.2
Leshchyns'ka, I.3
Schachner, M.4
-
60
-
-
28844477599
-
Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro
-
Kanaani, J., Prusiner, S. B., Diacovo, J., Baekkeskov, S. and Legname, G. Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro. J. Neurochem. 95 (2005) 1373-1386.
-
(2005)
J. Neurochem.
, vol.95
, pp. 1373-1386
-
-
Kanaani, J.1
Prusiner, S.B.2
Diacovo, J.3
Baekkeskov, S.4
Legname, G.5
-
61
-
-
21844452161
-
Unchanged scrapie pathology in brain tissue of tyrosine kinase Fyn-deficient mice
-
Schwarz, A., Burwinkel, M., Riemer, C., Schultz, J. and Baier, M. Unchanged scrapie pathology in brain tissue of tyrosine kinase Fyn-deficient mice. Neurodegener. Dis. 1 (2004) 266-268.
-
(2004)
Neurodegener. Dis.
, vol.1
, pp. 266-268
-
-
Schwarz, A.1
Burwinkel, M.2
Riemer, C.3
Schultz, J.4
Baier, M.5
-
62
-
-
13244255633
-
Prion-associated increases in Src-family kinases
-
Nixon, R. R. Prion-associated increases in Src-family kinases. J. Biol. Chem. 280 (2005) 2455-2462.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2455-2462
-
-
Nixon, R.R.1
-
63
-
-
33646174831
-
Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapieinfected neuronal cell lines
-
Gyllberg, H., Lofgren, K., Lindegren, H. and Bedecs, K. Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapieinfected neuronal cell lines. FEBS Lett. 580 (2006) 2603-2608.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2603-2608
-
-
Gyllberg, H.1
Lofgren, K.2
Lindegren, H.3
Bedecs, K.4
-
64
-
-
77955296897
-
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells
-
Didonna, A. and Legname, G. Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells. Mol. Neurodegener. 5 (2010) 29.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 29
-
-
Didonna, A.1
Legname, G.2
-
65
-
-
84866065959
-
Alzheimer amyloid-beta oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
-
Um, J. W., Nygaard, H. B., Heiss, J. K., Kostylev, M. A., Stagi, M., Vortmeyer, A., Wisniewski, T., Gunther, E. C. and Strittmatter, S. M. Alzheimer amyloid-beta oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. Nat. Neurosci. 15 (2012) 1227-1235.
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1227-1235
-
-
Um, J.W.1
Nygaard, H.B.2
Heiss, J.K.3
Kostylev, M.A.4
Stagi, M.5
Vortmeyer, A.6
Wisniewski, T.7
Gunther, E.C.8
Strittmatter, S.M.9
-
66
-
-
0345687168
-
NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells
-
Schneider, B., Mutel, V., Pietri, M., Ermonval, M., Mouillet-Richard, S. and Kellermann, O. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc. Natl. Acad. Sci. USA100 (2003) 13326-13331.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13326-13331
-
-
Schneider, B.1
Mutel, V.2
Pietri, M.3
Ermonval, M.4
Mouillet-Richard, S.5
Kellermann, O.6
-
67
-
-
85010209286
-
MAP kinases and histone modification
-
Suganuma, T. and Workman, J. L. MAP kinases and histone modification. J. Mol. Cell. Biol. 34 (2010) 1543-1551.
-
(2010)
J. Mol. Cell. Biol.
, vol.34
, pp. 1543-1551
-
-
Suganuma, T.1
Workman, J.L.2
-
68
-
-
30544444183
-
Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways
-
Lopes, M. H., Hajj, G. N., Muras, A. G., Mancini, G. L., Castro, R. M., Ribeiro, K. C., Brentani, R. R., Linden, R. and Martins, V. R. Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways. J. Neurosci. 25 (2005) 11330-11339.
-
(2005)
J. Neurosci.
, vol.25
, pp. 11330-11339
-
-
Lopes, M.H.1
Hajj, G.N.2
Muras, A.G.3
Mancini, G.L.4
Castro, R.M.5
Ribeiro, K.C.6
Brentani, R.R.7
Linden, R.8
Martins, V.R.9
-
69
-
-
33748776269
-
Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells
-
Pietri, M., Caprini, A., Mouillet-Richard, S., Pradines, E., Ermonval, M., Grassi, J., Kellermann, O. and Schneider, B. Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells. J. Biol. Chem. 281 (2006) 28470-28479.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28470-28479
-
-
Pietri, M.1
Caprini, A.2
Mouillet-Richard, S.3
Pradines, E.4
Ermonval, M.5
Grassi, J.6
Kellermann, O.7
Schneider, B.8
-
70
-
-
12544257289
-
Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment
-
Marella, M., Gaggioli, C., Batoz, M., Deckert, M., Tartare-Deckert, S. and Chabry, J. Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment. J. Biol. Chem. 280 (2005) 1529-1534.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1529-1534
-
-
Marella, M.1
Gaggioli, C.2
Batoz, M.3
Deckert, M.4
Tartare-Deckert, S.5
Chabry, J.6
-
71
-
-
26844548845
-
Activation of mitogen-activated protein kinases in hamster brains infected with 263K scrapie agent
-
Lee, H. P., Jun, Y. C., Choi, J. K., Kim, J. I., Carp, R. I. and Kim, Y. S. Activation of mitogen-activated protein kinases in hamster brains infected with 263K scrapie agent. J. Neurochem. 95 (2005) 584-593.
-
(2005)
J. Neurochem.
, vol.95
, pp. 584-593
-
-
Lee, H.P.1
Jun, Y.C.2
Choi, J.K.3
Kim, J.I.4
Carp, R.I.5
Kim, Y.S.6
-
72
-
-
20444499045
-
Activation of the JNKc-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection
-
Carimalo, J., Cronier, S., Petit, G., Peyrin, J. M., Boukhtouche, F., Arbez, N., Lemaigre-Dubreuil, Y., Brugg, B. and Miquel, M. C. Activation of the JNKc-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection. Eur. J. Neurosci. 21 (2005) 2311-2319.
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 2311-2319
-
-
Carimalo, J.1
Cronier, S.2
Petit, G.3
Peyrin, J.M.4
Boukhtouche, F.5
Arbez, N.6
Lemaigre-Dubreuil, Y.7
Brugg, B.8
Miquel, M.C.9
-
73
-
-
34648836753
-
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation
-
Thellung, S., Villa, V., Corsaro, A., Pellistri, F., Venezia, V., Russo, C., Aceto, A., Robello, M. and Florio, T. ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation. Glia55 (2007) 1469-1485.
-
(2007)
Glia
, vol.55
, pp. 1469-1485
-
-
Thellung, S.1
Villa, V.2
Corsaro, A.3
Pellistri, F.4
Venezia, V.5
Russo, C.6
Aceto, A.7
Robello, M.8
Florio, T.9
-
74
-
-
0031194455
-
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity
-
Brown, D. R., Schulz-Schaeffer, W. J., Schmidt, B. and Kretzschmar, H. A. Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp. Neurol. 146 (1997) 104-112.
-
(1997)
Exp. Neurol.
, vol.146
, pp. 104-112
-
-
Brown, D.R.1
Schulz-Schaeffer, W.J.2
Schmidt, B.3
Kretzschmar, H.A.4
-
75
-
-
24944524825
-
Inhibitors of the mitogen-activated protein kinase kinase 1/2 signaling pathway clear prion-infected cells from PrPSc
-
Nordstrom, E. K., Luhr, K. M., Ibanez, C. and Kristensson, K. Inhibitors of the mitogen-activated protein kinase kinase 1/2 signaling pathway clear prion-infected cells from PrPSc. J. Neurosci. 25 (2005) 8451-8456.
-
(2005)
J. Neurosci.
, vol.25
, pp. 8451-8456
-
-
Nordstrom, E.K.1
Luhr, K.M.2
Ibanez, C.3
Kristensson, K.4
-
76
-
-
42449102282
-
Resistance of cell lines to prion toxicity aided by phospho-ERK expression
-
Uppington, K. M. and Brown, D. R. Resistance of cell lines to prion toxicity aided by phospho-ERK expression. J. Neurochem. 105 (2008) 842-852.
-
(2008)
J. Neurochem.
, vol.105
, pp. 842-852
-
-
Uppington, K.M.1
Brown, D.R.2
-
77
-
-
77952170820
-
Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins
-
Pidoux, G. and Tasken, K. Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins. J. Mol. Endocrinol. 44 (2010) 271-284.
-
(2010)
J. Mol. Endocrinol.
, vol.44
, pp. 271-284
-
-
Pidoux, G.1
Tasken, K.2
-
78
-
-
80053305618
-
Cross-talk between calcium and protein kinase A in the regulation of cell migration
-
Howe, A. K. Cross-talk between calcium and protein kinase A in the regulation of cell migration. Curr. Opin. Cell Biol. 23 (2011) 554-561.
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 554-561
-
-
Howe, A.K.1
-
79
-
-
0036645677
-
Cellular prion protein transduces neuroprotective signals
-
Chiarini, L. B., Freitas, A. R., Zanata, S. M., Brentani, R. R., Martins, V. R. and Linden, R. Cellular prion protein transduces neuroprotective signals. EMBO J. 21 (2002) 3317-3326.
-
(2002)
EMBO J.
, vol.21
, pp. 3317-3326
-
-
Chiarini, L.B.1
Freitas, A.R.2
Zanata, S.M.3
Brentani, R.R.4
Martins, V.R.5
Linden, R.6
-
80
-
-
33845670034
-
The interaction between prion protein and laminin modulates memory consolidation
-
Coitinho, A. S., Freitas, A. R., Lopes, M. H., Hajj, G. N., Roesler, R., Walz, R., Rossato, J. I., Cammarota, M., Izquierdo, I., Martins, V. R. and Brentani, R. R. The interaction between prion protein and laminin modulates memory consolidation. Eur. J. Neurosci. 24 (2006) 3255-3264.
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 3255-3264
-
-
Coitinho, A.S.1
Freitas, A.R.2
Lopes, M.H.3
Hajj, G.N.4
Roesler, R.5
Walz, R.6
Rossato, J.I.7
Cammarota, M.8
Izquierdo, I.9
Martins, V.R.10
Brentani, R.R.11
-
81
-
-
84867705071
-
Protein kinase C (PKC) isozyme-specific substrates and their design
-
Kang, J. H., Toita, R., Kim, C. W. and Katayama, Y. Protein kinase C (PKC) isozyme-specific substrates and their design. Biotechnol. Adv. 30 (2012) 1662-1672.
-
(2012)
Biotechnol. Adv.
, vol.30
, pp. 1662-1672
-
-
Kang, J.H.1
Toita, R.2
Kim, C.W.3
Katayama, Y.4
-
82
-
-
77956932796
-
12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis
-
Zhang, B. and Xia, C. 12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis. Cell. Mol. Biol. Lett. 15 (2010) 377-394.
-
(2010)
Cell. Mol. Biol. Lett.
, vol.15
, pp. 377-394
-
-
Zhang, B.1
Xia, C.2
-
83
-
-
29144440982
-
Lymphoid signal transduction mechanisms linked to cellular prion protein
-
Mazzoni, I. E., Ledebur, H. C., Jr., Paramithiotis, E. and Cashman, N. Lymphoid signal transduction mechanisms linked to cellular prion protein. Biochem. Cell. Biol. 83 (2005) 644-653.
-
(2005)
Biochem. Cell. Biol.
, vol.83
, pp. 644-653
-
-
Mazzoni, I.E.1
Ledebur Jr., H.C.2
Paramithiotis, E.3
Cashman, N.4
-
84
-
-
1342273153
-
Immunoseparation of prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells
-
Botto, L., Masserini, M., Cassetti, A. and Palestini, P. Immunoseparation of prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells. FEBS Lett. 557 (2004) 143-147.
-
(2004)
FEBS Lett.
, vol.557
, pp. 143-147
-
-
Botto, L.1
Masserini, M.2
Cassetti, A.3
Palestini, P.4
-
85
-
-
33750685959
-
Group I mGluR signaling in BSE-infected bovine-PrP transgenic mice
-
Rodriguez, A., Martin, M., Albasanz, J. L., Barrachina, M., Espinosa, J. C., Torres, J. M. and Ferrer, I. Group I mGluR signaling in BSE-infected bovine-PrP transgenic mice. Neurosci. Lett. 410 (2006) 115-120.
-
(2006)
Neurosci. Lett.
, vol.410
, pp. 115-120
-
-
Rodriguez, A.1
Martin, M.2
Albasanz, J.L.3
Barrachina, M.4
Espinosa, J.C.5
Torres, J.M.6
Ferrer, I.7
-
87
-
-
84855718266
-
17beta-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway
-
Huang, J. G., Xia, C., Zheng, X. P., Yi, T. T., Wang, X. Y., Song, G. and Zhang, B. 17beta-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway. Cell. Mol. Biol. Lett. 16 (2011) 564-575.
-
(2011)
Cell. Mol. Biol. Lett.
, vol.16
, pp. 564-575
-
-
Huang, J.G.1
Xia, C.2
Zheng, X.P.3
Yi, T.T.4
Wang, X.Y.5
Song, G.6
Zhang, B.7
-
88
-
-
0345505687
-
Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival
-
Chen, S., Mange, A., Dong, L., Lehmann, S. and Schachner, M. Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival. Mol. Cell. Neurosci. 22 (2003) 227-233.
-
(2003)
Mol. Cell. Neurosci.
, vol.22
, pp. 227-233
-
-
Chen, S.1
Mange, A.2
Dong, L.3
Lehmann, S.4
Schachner, M.5
-
89
-
-
33646695909
-
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury
-
Weise, J., Sandau, R., Schwarting, S., Crome, O., Wrede, A., Schulz-Schaeffer, W., Zerr, I. and Bahr, M. Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury. Stroke37 (2006) 1296-1300.
-
(2006)
Stroke
, vol.37
, pp. 1296-1300
-
-
Weise, J.1
Sandau, R.2
Schwarting, S.3
Crome, O.4
Wrede, A.5
Schulz-Schaeffer, W.6
Zerr, I.7
Bahr, M.8
-
90
-
-
43049116184
-
Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia
-
Weise, J., Doeppner, T. R., Muller, T., Wrede, A., Schulz-Schaeffer, W., Zerr, I., Witte, O. W. and Bahr, M. Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia. Restor. Neurol. Neurosci. 26 (2008) 57-64.
-
(2008)
Restor. Neurol. Neurosci.
, vol.26
, pp. 57-64
-
-
Weise, J.1
Doeppner, T.R.2
Muller, T.3
Wrede, A.4
Schulz-Schaeffer, W.5
Zerr, I.6
Witte, O.W.7
Bahr, M.8
-
91
-
-
19344370943
-
Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival
-
Vassallo, N., Herms, J., Behrens, C., Krebs, B., Saeki, K., Onodera, T., Windl, O. and Kretzschmar, H. A. Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival. Biochem. Biophys. Res. Commun. 332 (2005) 75-82.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 75-82
-
-
Vassallo, N.1
Herms, J.2
Behrens, C.3
Krebs, B.4
Saeki, K.5
Onodera, T.6
Windl, O.7
Kretzschmar, H.A.8
-
92
-
-
48249155003
-
Evidence for an association of prion protein and sphingolipid-mediated signaling
-
Schmalzbauer, R., Eigenbrod, S., Winoto-Morbach, S., Xiang, W., Schutze, S., Bertsch, U. and Kretzschmar, H. A. Evidence for an association of prion protein and sphingolipid-mediated signaling. J. Neurochem. 106 (2008) 1459-1470.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1459-1470
-
-
Schmalzbauer, R.1
Eigenbrod, S.2
Winoto-Morbach, S.3
Xiang, W.4
Schutze, S.5
Bertsch, U.6
Kretzschmar, H.A.7
-
93
-
-
73949085497
-
Hypoxia protects neuronal cells from human prion protein fragment-induced apoptosis
-
Seo, J. S., Seol, J. W., Moon, M. H., Jeong, J. K., Lee, Y. J. and Park, S. Y. Hypoxia protects neuronal cells from human prion protein fragment-induced apoptosis. J. Neurochem. 112 (2010) 715-722.
-
(2010)
J. Neurochem.
, vol.112
, pp. 715-722
-
-
Seo, J.S.1
Seol, J.W.2
Moon, M.H.3
Jeong, J.K.4
Lee, Y.J.5
Park, S.Y.6
-
94
-
-
77955595618
-
Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR
-
Roffe, M., Beraldo, F. H., Bester, R., Nunziante, M., Bach, C., Mancini, G., Gilch, S., Vorberg, I., Castilho, B. A., Martins, V. R. and Hajj, G. N. Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR. Proc. Natl. Acad. Sci. USA107 (2010) 13147-13152.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 13147-13152
-
-
Roffe, M.1
Beraldo, F.H.2
Bester, R.3
Nunziante, M.4
Bach, C.5
Mancini, G.6
Gilch, S.7
Vorberg, I.8
Castilho, B.A.9
Martins, V.R.10
Hajj, G.N.11
-
95
-
-
84872551479
-
Multilevel complexity of calcium signaling: Modeling angiogenesis
-
Munaron, L. and Scianna, M. Multilevel complexity of calcium signaling: Modeling angiogenesis. World J. Biol. Chem. 3 (2012) 121-126.
-
(2012)
World J. Biol. Chem.
, vol.3
, pp. 121-126
-
-
Munaron, L.1
Scianna, M.2
-
96
-
-
79959519400
-
Possible role for Ca2+ in the pathophysiology of the prion protein?
-
Peggion, C., Bertoli, A. and Sorgato, M. C. Possible role for Ca2+ in the pathophysiology of the prion protein? Biofactors37 (2011) 241-249.
-
(2011)
Biofactors
, vol.37
, pp. 241-249
-
-
Peggion, C.1
Bertoli, A.2
Sorgato, M.C.3
-
97
-
-
0029971378
-
Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents
-
Colling, S. B., Collinge, J. and Jefferys, J. G. Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents. Neurosci. Lett. 209 (1996) 49-52.
-
(1996)
Neurosci. Lett.
, vol.209
, pp. 49-52
-
-
Colling, S.B.1
Collinge, J.2
Jefferys, J.G.3
-
98
-
-
0033817026
-
Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice
-
Herms, J. W., Korte, S., Gall, S., Schneider, I., Dunker, S. and Kretzschmar, H. A. Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice. J. Neurochem. 75 (2000) 1487-1492.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1487-1492
-
-
Herms, J.W.1
Korte, S.2
Gall, S.3
Schneider, I.4
Dunker, S.5
Kretzschmar, H.A.6
-
99
-
-
0035033675
-
Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells
-
Herms, J. W., Tings, T., Dunker, S. and Kretzschmar, H. A. Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells. Neurobiol. Dis. 8 (2001) 324-330.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 324-330
-
-
Herms, J.W.1
Tings, T.2
Dunker, S.3
Kretzschmar, H.A.4
-
100
-
-
33748029508
-
Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons
-
Fuhrmann, M., Bittner, T., Mitteregger, G., Haider, N., Moosmang, S., Kretzschmar, H. and Herms, J. Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons. J. Neurochem. 98 (2006) 1876-1885.
-
(2006)
J. Neurochem.
, vol.98
, pp. 1876-1885
-
-
Fuhrmann, M.1
Bittner, T.2
Mitteregger, G.3
Haider, N.4
Moosmang, S.5
Kretzschmar, H.6
Herms, J.7
-
101
-
-
0029557978
-
Regulation of intracellular free calcium levels by the cellular prion protein
-
Whatley, S. A., Powell, J. F., Politopoulou, G., Campbell, I. C., Brammer, M. J. and Percy, N. S. Regulation of intracellular free calcium levels by the cellular prion protein. Neuroreport6 (1995) 2333-2337.
-
(1995)
Neuroreport
, vol.6
, pp. 2333-2337
-
-
Whatley, S.A.1
Powell, J.F.2
Politopoulou, G.3
Campbell, I.C.4
Brammer, M.J.5
Percy, N.S.6
-
102
-
-
0345687495
-
Modulation of L-type voltage-gated calcium channels by recombinant prion protein
-
Korte, S., Vassallo, N., Kramer, M. L., Kretzschmar, H. A. and Herms, J. Modulation of L-type voltage-gated calcium channels by recombinant prion protein. J. Neurochem. 87 (2003) 1037-1042.
-
(2003)
J. Neurochem.
, vol.87
, pp. 1037-1042
-
-
Korte, S.1
Vassallo, N.2
Kramer, M.L.3
Kretzschmar, H.A.4
Herms, J.5
-
103
-
-
43049180250
-
Alterations in Ca2+-buffering in prion-null mice: association with reduced afterhyperpolarizations in CA1 hippocampal neurons
-
Powell, A. D., Toescu, E. C., Collinge, J. and Jefferys, J. G. Alterations in Ca2+-buffering in prion-null mice: association with reduced afterhyperpolarizations in CA1 hippocampal neurons. J. Neurosci. 28 (2008) 3877-3886.
-
(2008)
J. Neurosci.
, vol.28
, pp. 3877-3886
-
-
Powell, A.D.1
Toescu, E.C.2
Collinge, J.3
Jefferys, J.G.4
-
104
-
-
79851481136
-
Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons
-
Lazzari, C., Peggion, C., Stella, R., Massimino, M. L., Lim, D., Bertoli, A. and Sorgato, M. C. Cellular prion protein is implicated in the regulation of local Ca2+ movements in cerebellar granule neurons. J. Neurochem. 116 (2011) 881-890.
-
(2011)
J. Neurochem.
, vol.116
, pp. 881-890
-
-
Lazzari, C.1
Peggion, C.2
Stella, R.3
Massimino, M.L.4
Lim, D.5
Bertoli, A.6
Sorgato, M.C.7
-
105
-
-
34249092704
-
Calcium and neurodegeneration
-
Mattson, M. P. Calcium and neurodegeneration. Aging Cell6 (2007) 337-350.
-
(2007)
Aging Cell
, vol.6
, pp. 337-350
-
-
Mattson, M.P.1
-
106
-
-
0027372884
-
Scrapie prions alter receptor-mediated calcium responses in cultured cells
-
Kristensson, K., Feuerstein, B., Taraboulos, A., Hyun, W. C., Prusiner, S. B. and DeArmond, S. J. Scrapie prions alter receptor-mediated calcium responses in cultured cells. Neurology43 (1993) 2335-2341.
-
(1993)
Neurology
, vol.43
, pp. 2335-2341
-
-
Kristensson, K.1
Feuerstein, B.2
Taraboulos, A.3
Hyun, W.C.4
Prusiner, S.B.5
DeArmond, S.J.6
-
107
-
-
0032701489
-
Intrinsic physiological and morphological properties of principal cells of the hippocampus and neocortex in hamsters infected with scrapie
-
Barrow, P. A., Holmgren, C. D., Tapper, A. J. and Jefferys, J. G. Intrinsic physiological and morphological properties of principal cells of the hippocampus and neocortex in hamsters infected with scrapie. Neurobiol. Dis. 6 (1999) 406-423.
-
(1999)
Neurobiol. Dis.
, vol.6
, pp. 406-423
-
-
Barrow, P.A.1
Holmgren, C.D.2
Tapper, A.J.3
Jefferys, J.G.4
-
108
-
-
0032101845
-
Alterations in potassium currents may trigger neurodegeneration in murine scrapie
-
Johnston, A. R., Fraser, J. R., Jeffrey, M. and MacLeod, N. Alterations in potassium currents may trigger neurodegeneration in murine scrapie. Exp. Neurol. 151 (1998) 326-333.
-
(1998)
Exp. Neurol.
, vol.151
, pp. 326-333
-
-
Johnston, A.R.1
Fraser, J.R.2
Jeffrey, M.3
MacLeod, N.4
-
109
-
-
0032213349
-
Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line
-
Florio, T., Thellung, S., Amico, C., Robello, M., Salmona, M., Bugiani, O., Tagliavini, F., Forloni, G. and Schettini, G. Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line. J. Neurosci. Res. 54 (1998) 341-352.
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 341-352
-
-
Florio, T.1
Thellung, S.2
Amico, C.3
Robello, M.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
Forloni, G.8
Schettini, G.9
-
110
-
-
0033826141
-
Apoptotic cell death and impairment of L-type voltagesensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126
-
Thellung, S., Florio, T., Villa, V., Corsaro, A., Arena, S., Amico, C., Robello, M., Salmona, M., Forloni, G., Bugiani, O., Tagliavini, F. and Schettini, G. Apoptotic cell death and impairment of L-type voltagesensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126. Neurobiol. Dis. 7 (2000) 299-309.
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 299-309
-
-
Thellung, S.1
Florio, T.2
Villa, V.3
Corsaro, A.4
Arena, S.5
Amico, C.6
Robello, M.7
Salmona, M.8
Forloni, G.9
Bugiani, O.10
Tagliavini, F.11
Schettini, G.12
-
111
-
-
1642578920
-
Scrapieinfected GT1-1 cells show impaired function of voltage-gated N-type calcium channels (Ca(v) 2.2) which is ameliorated by quinacrine treatment
-
Sandberg, M. K., Wallen, P., Wikstrom, M. A. and Kristensson, K. Scrapieinfected GT1-1 cells show impaired function of voltage-gated N-type calcium channels (Ca(v) 2. 2) which is ameliorated by quinacrine treatment. Neurobiol. Dis. 15 (2004) 143-151.
-
(2004)
Neurobiol. Dis.
, vol.15
, pp. 143-151
-
-
Sandberg, M.K.1
Wallen, P.2
Wikstrom, M.A.3
Kristensson, K.4
-
112
-
-
78650843400
-
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress
-
Torres, M., Castillo, K., Armisen, R., Stutzin, A., Soto, C. and Hetz, C. Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. PLOS One5 (2010) e15658.
-
(2010)
PLOS One
, vol.5
-
-
Torres, M.1
Castillo, K.2
Armisen, R.3
Stutzin, A.4
Soto, C.5
Hetz, C.6
-
113
-
-
0042411243
-
Neuronal apoptosis in human prion diseases
-
Gray, F., Adle-Biassette, H., Chretien, F., Ereau, T., Delisle, M. B. and Vital, C. Neuronal apoptosis in human prion diseases. Bull. Acad. Natl. Med. 183 (1999) 305-320; discussion 320-301.
-
(1999)
Bull. Acad. Natl. Med.
, vol.183
, pp. 305-320
-
-
Gray, F.1
Adle-Biassette, H.2
Chretien, F.3
Ereau, T.4
Delisle, M.B.5
Vital, C.6
-
114
-
-
0036154536
-
MHC and MHCrelated proteins as pleiotropic signal molecules
-
Ojcius, D. M., Delarbre, C., Kourilsky, P. and Gachelin, G. MHC and MHCrelated proteins as pleiotropic signal molecules. FASEB J. 16 (2002) 202-206.
-
(2002)
FASEB J.
, vol.16
, pp. 202-206
-
-
Ojcius, D.M.1
Delarbre, C.2
Kourilsky, P.3
Gachelin, G.4
|