Infrared microspectroscopy: A multiple-screening platform for investigating single-cell biochemical perturbations upon prion infection

ACS Chemical Neuroscience

Volumn 2, Issue 3, 2011, Pages 160-174

  Didonna, Alessandro ^a   Vaccari, Lisa ^b   Bek, Alpan ^c   Legname, Giuseppe ^a,b,c,d  

^a SISSA   (Italy)

^b SINCROTRONE TRIESTE   (Italy)

^c CBM Scrl   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

atomic force microscopy; chemical mapping; infrared microspectroscopy; Prion; PrPSc; synchrotron radiation

Indexed keywords

CALCEIN; LIPID; PHOSPHOLIPID; PROTEIN; PROTEINASE K;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOASSAY; CELL CYCLE; CELL INTERACTION; CELL SELECTION; CELL STRUCTURE; CELL VIABILITY; CELL VOLUME; CELLULAR DISTRIBUTION; CLUSTER ANALYSIS; CYTOPLASM; FLOW CYTOMETRY; HIERARCHICAL CLUSTER ANALYSIS; INFRARED RADIATION; INFRARED SPECTROSCOPY; LYSOSOME; MICROSCOPY; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN METABOLISM; SYNCHROTRON; SYNCHROTRON INFRARED SOURCE FOR SPECTROSCOPY AND IMAGING; SYNCHROTRON RADIATION; SYNCHROTRON RADIATION INFRARED MICROSPECTROSCOPY; VIRUS DIAGNOSIS; WHOLE CELL;

ATOMIC FORCE MICROSCOPY; CHEMICAL MAPPING; INFRARED MICROSPECTROSCOPY; PRION; PRPSC; SYNCHROTRON RADIATION;

ANIMALS; MICE; MICROSPECTROPHOTOMETRY; PRION DISEASES; PRPSC PROTEINS; SINGLE-CELL ANALYSIS; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 79952795300     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn1000952     Document Type: Article

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