17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway

Cellular and Molecular Biology Letters

Volumn 16, Issue 4, 2011, Pages 564-575

  Huang, Jia Gu ^a,b   Xia, Chun ^a   Zheng, Xin Peng ^a   Yi, Ting Ting ^a   Wang, Xiao Yong ^b   Song, Gang ^a   Zhang, Bing ^a  

^a XIAMEN UNIVERSITY   (China)

^b Ningde Municipal Hospital   (China)

Author keywords

17 estradiol; Akt; Cell proliferation; Estrogen receptor; Osteoarthritis; PI3K Akt pathway; Rat osteoarthritis model chondrocyte

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; INTERLEUKIN 1BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HORMONE ACTION; MALE; NEWBORN; NONHUMAN; OSTEOARTHRITIS; PROTEIN EXPRESSION; RAT; SEX HORMONE DETERMINATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; WESTERN BLOTTING;

RATTUS;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; ESTRADIOL; GENE EXPRESSION; INTERLEUKIN-1BETA; OSTEOARTHRITIS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

EID: 84855718266     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-011-0023-y     Document Type: Article

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