Simian immunodeficiency virus (SIV) envelope-specific Fabs with high- level homologous neutralizing activity: Recovery from a long-term- nonprogressor SIV-infected macaque

Journal of Virology

Volumn 72, Issue 1, 1998, Pages 585-592

  Glamann, Joakim ^a   Burton, Dennis R ^b   Parren, Paul W H I ^b   Ditzel, Henrik J ^b   Kent, Karen A ^c   Arnold, Caroline ^c   Montefiori, David ^d   Hirsch, Vanessa M ^a,e  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; MACACA; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CELL INTERACTION; VIRUS ENVELOPE; VIRUS ISOLATION;

EID: 0031964765     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.1.585-592.1998     Document Type: Article

References (53)

1. Almond, N., A. Jenkins, A. Slade, H. A. M. Cranage, and P. Kitchin. 1992. Population sequence analysis of simian immunodeficiency (32H reisolate of SIVmac251): a virus stock used for international vaccine studies. AIDS Res. Hum. Retroviruses 8:77-88.
2. Barbas, C. F., III, A. S. Rang, R. A. Lerner, and S. J. Benkovic. 1991. Assembly of combinatorial antibody libraries on phagc surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88:7978-7982.
3. Benichou, S., R. Legrand, N. Nakagawa, T. Taure, F. Traincard, G. Vogt, D. Dormont, P. Tiollais, M.-P. Kieny, and P. Madaule. 1992. Identification of a neutralizing domain in the external envelope glycoprotein of simian immunodeficiency virus. AIDS Res. Hum. Retroviruses 8:1165-1170.
4. Benos, D. J., B. H. Hahn, J. K. Bubien, S. K. Ghosh, N. A. Mashburn, M. A. Chaikin, G. M. Shaw, and E. N. Benveniste. 1994. Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc. Natl. Acad. Sci. USA 91:494-498.
5. Binley, J. M., H. J. Ditzel, C. F. Barbas III, N. Sullivan, J. Sodroski, P. W. Parren, and D. R. Burton. 1996. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding. AIDS Res. Hum. Retroviruses 12:911-924.
6. Buchbinder, S. P., M. H. Katz, N. A. Hessol, P. M. O'Malley, and S. D. Holmberg. 1994. Lone-term HIV-1 infection without immunological progression. AIDS 8:1123-1128.
7. Burton, D. R., C. F. Barbas III, M. A. A. Persson, S. Koening, R. M. Chanock, and R. A. Lerner. 1991. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc. Natl. Acad. Sci. USA 88:10134-10137.
8. Choi, W. S., C. Collignon, C. Thiriart, D. P. W. Burns, E. J. Stott, K. A. Kent, and R. C. Desrosiers. 1994. Effects of natural sequence variation on recognition by monoclonal antibodies that neutralize simian immunodeficiency virus infectivity. J. Virol. 68:5395-5402.
9. Clement, J. E., R. C. Montelaro, M. C. Zink, A. M. Amedee, S. Miller, A. M. Trichel, B. Jagerski, D. Hauer, L. N. Martin, R. P. Bohm, and M. Murphey-Corb. 1995. Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus. J. Virol. 69:2737-2744.
10. Cook, G. P., and I. M. Tomlinson. 1995. The human immunoglobulin VH repertoire. Immunol. Today 16:237-242.
11. Desrosiers, R. C. 1990. The simian immunodeficiency viruses. Annu. Rev. Immunol. 8:557-578.
12. Fouts, T. R., J. M. Binley, A. Trkola, J. E. Robinson, and J. P. Moore. 1997. Neutralization of the human immunodeficiency virus type 1 primary isolate JR-FL by human monoclonal antibodies correlates with antibody binding to the oligomeric form of the envelope glycoprotein complex. J. Virol. 71:2779-2785.
13. Gardner, M., A. Rosenthal, M. Jennings, J. Yee, L. Antipa, and E. Robinson. 1995. Passive immunization of rhesus macaques against SIV infection and disease. AIDS Res. Hum. Retroviruses 11:843-854.
14. Haigwood, N. L., A. Watson, W. F. Sutton, J. McClure, A. Lewis, J. Ranchis, B. Travis, G. Voss, N. Letvin, S.-L. Hu, V. M. Hirsch, and P. R. Johnson. 1996. Passive immune globulin therapy in the SIV/macaque model: early intervention can alter disease profile. Immunol. Lett. 51:107-114.
15. Hirsch, V., D. Adger-Johnson, B. Campbell, S. Goldstein, C. Brown, W. R. Elkins, and D. C. Montefiori. 1997. A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3. J. Virol. 71:1608-1620.
16. Huse, W. D., L. Sastry, S. A. Iverson, A. S. Kang, M. Alting-Mees, D. R. Burton, S. J. Benkovic, and R. A. Lerner. 1989. Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science 246:1275-1281.
17. Ivey-Hoyle, M., J. S. Culp, M. A. Chaikin, B. D. Hellmig, T. J. Matthews, R. W. Sweet, and M. Rosenberg. 1991. Envelope glycoproteins from biologically diverse isolates of human immunodeficiency viruses have widely different affinities for CD4. Proc. Natl. Acad. Sci. USA 88:512-516.
18. Javaherian, K., A. J. Langlois, C. McDanal, K. L. Ross, L. I. Eckler, C. L. Hellis, A. T. Profy, J. R. Rusche, D. P. Bolognesi, S. D. Putney, and T. J. Matthews. 1989. Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein. Proc. Natl. Acad. Sci. USA 86:6768-6772.
19. Javaherian, K., A. J. Langlois, D. C. Montefiori, K. A. Kent, K. A. Ryan, P. D. Wyman, J. Stott, D. P. Bolognesi, M. Murphey-Corb, and G. J. Larosa. 1994. Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein. J. Virol. 68:2624-2631.
20. Javaherian, K., A. J. Langlois, S. Schmidt, M. Kaufmann, N. Cates, J. P. M. Langedijk, R. H. Meloen, R. C. Desrosiers, D. P. W. Burns, D. P. Bolognesi, G. J. LaRosa, and S. D. Putney. 1992. The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 89:1418-1422.
21. Kabat, E. A., T. T. Wu, H. M. Perry, K. S. Gottesman, and C. Foeller. 1991. Sequences of proteins of immunological interest, 5th ed. U.S. Department of Health and Human Services, Bethesda, Md.
22. Kent, K., C. Powell, T. Corcoran, A. Jenkins, N. Almond, I. Jones, J. Robinson, and E. J. Stott. 1993. Characterisation of neutralising epitopes on simian immunodeficiency virus envelope using monoclonal antibodies, p. 167-172. In Huitieme colloque des cent gardes. Fondation Marcel Merieux, Lyon, France.
23. Kent, K. A., L. Gritz, G. Stallard, M. P. Crangage, C. Collignon, C. Thiriart, T. Corcoran, P. Silvera, and E. J. Stott. 1991. Production and characterisation of monoclonal antibodies to simian immunodeficiency virus envelope glycoproteins. AIDS 5:829-836.
24. Kent, K. A., P. Kitchen, K. H. G. Mills, M. Page, F. Taffs, T. Corcoran, P. Silvera, B. Flanagan, C. Powell, J. Rose, C. Ling, A. M. Aubertin, and E. J. Stott. 1994. Passive immunization of cynomolgus macaques with immune sera or a pool of neutralizing monoclonal antibodies failed to protect against challenge with SIVmac251. AIDS Res. Hum. Retroviruses 10:189-194.
25. Kent, K. A., E. Rud, T. Corcoran, C. Powell, C. Thiriart, C. Collignon, and E. J. Stott. 1992. Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodies. AIDS Res. Hum. Retroviruses 8:1147-1151.
26. Kong, L. I., S. Lee, J. C. Kappes, J. S. Parkin, D. Decker, J. A. Hoxie, B. H. Hahn, and G. M. Shaw. 1988. West African HIV-2-related human retrovirus with attenuated cytopathicity. Science 240:1525-1529.
27. Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
28. Kriegler, M. 1990. Gene transfer and expression: a laboratory manual. W. H. Freeman & Company, New York, N.Y.
29. Lewis, M. G., W. R. Elkins, F. McCutchan, R. E. Benveniste, C. Y. Lai, D. C. Montefiori, D. S. Burke, G. A. Eddy, and A. Shafferman. 1993. Passively transferred antibodies directed against conserved regions of SIV envelope protect macaques from SIV infection. Vaccine 11:1347-1355.
30. Marks, J. D., H. R. Hoogenboom, T. P. Bonnert, J. McCafferty, A. D. Griffiths, and G. Winter. 1991. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222:581-597.
31. Miller, M. A., M. Murphey-Corb, and R. C. Montelaro. 1992. Identification of broadly reactive continuous antigenic determinants of simian immunodeficiency virus glycoproteins. AIDS Res. Hum. Retroviruses 8:1153-1164.
32. Montefiori, D. C., W. E. Robinson, Jr., S. S. Schuffman, and W. M. Mitchell. 1988. Evaluation of antiviral drugs and neutralizing antibodies to human immunodeficiency virus by rapid and sensitive microtiter infection assay. J. Clin. Microbiol. 26:231-235.
33. Moore, J. P., Y. Cao, L. Qing, Q. J. Sattentau, J. Pyati, R. Koduri, J. Robinson, C. F. Barbas III, D. R. Burton, and D. D. Ho. 1995. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J. Virol. 69:101-109.
34. Moore, J. P., and D. D. Ho. 1993. Antibodies to discontinuous or conformationallv sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans. J. Virol. 67:863-875.
35. + lymphocytes. J. Acquired Immune Detic. Syndr. 8:496-505.
36. Palker, T. J., M. E. Clark, A. J. Langlois, T. J. Matthews, K. J. Winhold, R. R. Randall, D. P. Bolognesi, and B. F. Haynes. 1988. Type-specific neutralization of the human immunodeficiency virus with antibodies to envencoded synthetic peptides. Proc. Natl. Acad. Sci. USA 85:1932-1936.
37. Planelles, V., N. L. Haigwood, M. L. Marthas, K. A. Mann, C. Scandella, W. D. Lidster, J. R. Schuster, R. van Kuyk, P. A. Marx, M. B. Gardner, and P. A. Luciw. 1991. Functional and immunological characterization of SIV envelope glycoprotein produced in genetically engineered mammalian cells. AIDS Res. Hum. Retroviruses 7:889-896.
38. Putkonen, P., R. Thorstensson, L. Ghavamzadeh, J. Albert, K. Hild, G. Biberfeld, and E. Norrby. 1991. Prevention of HIV-2 and SIVsm infection by passive immunization in cynomolgus monkeys. Nature 352:436-438.
39. Roben, P., J. P. Moore, M. Thali, J. Sodroski, C. F. Barbas III, and D. R. Burton. 1994. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding sites of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1. J. Virol. 68:4821-4828.
40. Samuelsson, A., F. Chiodi, P. Ohman, P. Putkonen, E. Norrby, and M. A. Persson. 1995. Chimeric macaque/human Fab molecules neutralize simian immunodeficiency virus. Virology 207:495-502.
41. Sattentau, Q. J., and J. P. Moore. 1995. Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer. J. Exp. Med. 182:185-196.
42. Scandella, V., J. Kilpatrick, W. Lidster, C. Parker, G. K. Moore, K. A. Mann, P. Brown, S. Coates, B. A. Chapman, F. Maziarz, K. S. Steimer, and N. L. Haigwood. 1993. Non-affinity purification of recombinant gp120 for use in AIDS vaccine development. AIDS Res. Hum. Retroviruses 9:1227-1238.
43. Sheppard, H. W., W. Lang, M. S. Ascher, E. Vittinghoff, and W. Winkelstein. 1993. The characterization of non-progressors: long-term HIV-1 infection with stable CD4 22 T-cell levels. AIDS 7:1159-1166.
44. Silvera, P., B. Flanagan, K. Kent, E. Rud, C. Powell, T. Corcoran, C. Bruck, C. Thiriart, N. L. Haigwood, and E. J. Stott. 1994. Fine analysis of humoral antibody response to envelope glycoprotein of SIV in infected and vaccinated macaques. AIDS Res. Hum. Retroviruses 10:1295-1304.
45. Steimer, K. S., C. J. Scandella, P. V. Skiles, and N. L. Haigwood. 1991. Neutralization of divergent HIV-1 isolates by conformation-dependent human antibodies to gp120. Science 254:105-108.
46. Sullivan, N., Y. Sun, J. Li, W. Hofman, and J. Sodroski. 1995. Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates. J. Virol. 69:4413-4422.
47. Tomlinson, I. M., G. Walter, J. D. Marks, M. B. Llewelyn, and G. Winter. 1992. The repertoire of human germline VH segment reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:776-798.
48. Vancott, T. C., V. R. Polonis, L. D. Loomis, N. L. Michael, P. L. Nara, and D. L. Birx. 1995. Differential role of V3-specific antibodies in neutralization assays involving primary and laboratory-adapted isolates of HIV type 1. AIDS Res. Hum. Retroviruses 11:1379-1390.
49. Van Rompay, K. K. A., M. G. Otsyula, R. P. Tarara, D. R. Canfield, C. Berardi, M. B. McChesney, and M. L. Marthas. 1996. Vaccination of pregnant macaques protects newborns against mucosal simian immunodeficiency virus infection. J. Infect. Dis. 173:1327-1335.
50. Weng, N., J. G. Snyder, L. Yu-Lee, and D. M. Marcus. 1992. Polymorphism of human immunoglobulin VH4 germ-line genes. Eur. J. Immunol. 22:1075-1082.
51. Winkler, T. H., H. Fehr, and J. R. Kalden. 1992. Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas. Eur. J. Immunol. 22:1719-1728.
52. + lymphocyte response in acutely infected rhesus monkeys. J. Virol. 67:1707-1711.
53. Zhang, J., L. N. Martin, E. A. Watson, R. C. Montelaro, M. West, L. Epstein, and M. Murphey-Corb. 1988. Simian immunodeficiency virus/Delta-induced immunodeficiency disease in rhesus monkeys: relation of antibody response and antigenemia. J. Infect. Dis. 158:1277-1286.