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Volumn 46, Issue 5, 2009, Pages 917-926

Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1

Author keywords

Anti HIV 1 antibodies; Human monoclonal antibodies; Immunoglobulin gene usage

Indexed keywords

ANTI V3 MONOCLONAL ANTIBODY; CD4 ANTIBODY; EPITOPE; GLYCOPROTEIN; GP41; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 59249105235     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.09.005     Document Type: Article
Times cited : (84)

References (61)
  • 1
    • 0025868277 scopus 로고
    • Molecular characterization of five human anti-HIV-1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response
    • Andris J.S., Johnson S., Zolla-Pazner S., and Capra J.D. Molecular characterization of five human anti-HIV-1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 7783-7787
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 7783-7787
    • Andris, J.S.1    Johnson, S.2    Zolla-Pazner, S.3    Capra, J.D.4
  • 2
    • 0031968725 scopus 로고    scopus 로고
    • Passive immunization with a human immunodeficiency virus type-1 neutralizing monoclonal antibody in Hu-PBL-SCID mice: isolation of a neutralization escape variant
    • Andrus L., Prince A.M., Bernal I., McCormack P., Lee D.H., Gorny M.K., and Zolla-Pazner S. Passive immunization with a human immunodeficiency virus type-1 neutralizing monoclonal antibody in Hu-PBL-SCID mice: isolation of a neutralization escape variant. J. Infect. Dis. 177 (1998) 889-897
    • (1998) J. Infect. Dis. , vol.177 , pp. 889-897
    • Andrus, L.1    Prince, A.M.2    Bernal, I.3    McCormack, P.4    Lee, D.H.5    Gorny, M.K.6    Zolla-Pazner, S.7
  • 3
    • 0028001662 scopus 로고
    • Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120
    • Bagley J., Dillon P.J., Rosen C., Robinson J., Sodroski J., and Marasco W.A. Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120. Mol. Immunol. 31 (1994) 1149-1160
    • (1994) Mol. Immunol. , vol.31 , pp. 1149-1160
    • Bagley, J.1    Dillon, P.J.2    Rosen, C.3    Robinson, J.4    Sodroski, J.5    Marasco, W.A.6
  • 5
    • 31844455573 scopus 로고    scopus 로고
    • Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies
    • Baxendale H.E., and Goldblatt D. Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies. Infect. Immun. 74 (2006) 1025-1031
    • (2006) Infect. Immun. , vol.74 , pp. 1025-1031
    • Baxendale, H.E.1    Goldblatt, D.2
  • 6
    • 0027340737 scopus 로고
    • Immunoglobulin VH3 gene products: natural ligands for HIV gp120
    • Berberian L., Goodglick L., Kipps T.J., and Braun J. Immunoglobulin VH3 gene products: natural ligands for HIV gp120. Science 261 (1993) 1588-1591
    • (1993) Science , vol.261 , pp. 1588-1591
    • Berberian, L.1    Goodglick, L.2    Kipps, T.J.3    Braun, J.4
  • 8
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek H.P., Brezinschek R.I., and Lipsky P.E. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J. Immunol. 155 (1995) 190-202
    • (1995) J. Immunol. , vol.155 , pp. 190-202
    • Brezinschek, H.P.1    Brezinschek, R.I.2    Lipsky, P.E.3
  • 10
    • 0032552454 scopus 로고    scopus 로고
    • Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41
    • Cavacini L.A., Emes C.L., Wisnewski A.V., Power J., Lewis G., Montefiori D., and Posner M.R. Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41. AIDS Res. Hum. Retroviruses 14 (1998) 1271-1280
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1271-1280
    • Cavacini, L.A.1    Emes, C.L.2    Wisnewski, A.V.3    Power, J.4    Lewis, G.5    Montefiori, D.6    Posner, M.R.7
  • 11
    • 0028986982 scopus 로고
    • The human immunoglobulin VH repertoire
    • Cook G.P., and Tomlinson I.M. The human immunoglobulin VH repertoire. Immunol. Today 16 (1995) 237-242
    • (1995) Immunol. Today , vol.16 , pp. 237-242
    • Cook, G.P.1    Tomlinson, I.M.2
  • 12
    • 0029068368 scopus 로고
    • Selective variations in vivo of VH3 and VH1 gene family expression in peripheral B cell IgM, IgD and IgG during HIV infection
    • David D., Demaison C., Bani L., Zouali M., and Theze J. Selective variations in vivo of VH3 and VH1 gene family expression in peripheral B cell IgM, IgD and IgG during HIV infection. Eur. J. Immunol. 25 (1995) 1524-1528
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1524-1528
    • David, D.1    Demaison, C.2    Bani, L.3    Zouali, M.4    Theze, J.5
  • 13
    • 0029093328 scopus 로고
    • Molecular characterization of human monoclonal antibodies specific for several HIV proteins: analysis of the VH3 family expression
    • David D., Goossens D., Desgranges C., Theze J., and Zouali M. Molecular characterization of human monoclonal antibodies specific for several HIV proteins: analysis of the VH3 family expression. Immunol. Lett. 47 (1995) 107-112
    • (1995) Immunol. Lett. , vol.47 , pp. 107-112
    • David, D.1    Goossens, D.2    Desgranges, C.3    Theze, J.4    Zouali, M.5
  • 15
    • 0036207634 scopus 로고    scopus 로고
    • Salivary gland B cell lymphoproliferative disorders in Sjogren's syndrome present a restricted use of antigen receptor gene segments similar to those used by hepatitis C virus-associated non-Hodgkins's lymphomas
    • De Re V., De Vita S., Gasparotto D., Marzotto A., Carbone A., Ferraccioli G., and Boiocchi M. Salivary gland B cell lymphoproliferative disorders in Sjogren's syndrome present a restricted use of antigen receptor gene segments similar to those used by hepatitis C virus-associated non-Hodgkins's lymphomas. Eur. J. Immunol. 32 (2002) 903-910
    • (2002) Eur. J. Immunol. , vol.32 , pp. 903-910
    • De Re, V.1    De Vita, S.2    Gasparotto, D.3    Marzotto, A.4    Carbone, A.5    Ferraccioli, G.6    Boiocchi, M.7
  • 17
    • 0031552347 scopus 로고    scopus 로고
    • Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries
    • Ditzel H.J., Parren P.W., Binley J.M., Sodroski J., Moore J.P., Barbas III C.F., and Burton D.R. Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries. J. Mol. Biol. 267 (1997) 684-695
    • (1997) J. Mol. Biol. , vol.267 , pp. 684-695
    • Ditzel, H.J.1    Parren, P.W.2    Binley, J.M.3    Sodroski, J.4    Moore, J.P.5    Barbas III, C.F.6    Burton, D.R.7
  • 19
    • 0025160356 scopus 로고
    • Nucleotide sequences of the cDNAs encoding the V-regions of H- and L-chains of a human monoclonal antibody specific to HIV-1-gp41
    • Felgenhauer M., Kohl J., and Ruker F. Nucleotide sequences of the cDNAs encoding the V-regions of H- and L-chains of a human monoclonal antibody specific to HIV-1-gp41. Nucleic Acids Res. 18 (1990) 4927
    • (1990) Nucleic Acids Res. , vol.18 , pp. 4927
    • Felgenhauer, M.1    Kohl, J.2    Ruker, F.3
  • 20
    • 0005534134 scopus 로고
    • Production of human monoclonal antibodies via fusion of Epstein-Barr virus-transformed lymphocytes with heteromyeloma
    • Celis J.E. (Ed), Academic Press
    • Gorny M.K. Production of human monoclonal antibodies via fusion of Epstein-Barr virus-transformed lymphocytes with heteromyeloma. In: Celis J.E. (Ed). Cell Biology: A Laboratory Handbook vol. 2 (1994), Academic Press 276-281
    • (1994) Cell Biology: A Laboratory Handbook , vol.2 , pp. 276-281
    • Gorny, M.K.1
  • 24
    • 0027311936 scopus 로고
    • Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120
    • Gorny M.K., Xu J.-Y., Karwowska S., Buchbinder A., and Zolla-Pazner S. Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120. J. Immunol. 150 (1993) 635-643
    • (1993) J. Immunol. , vol.150 , pp. 635-643
    • Gorny, M.K.1    Xu, J.-Y.2    Karwowska, S.3    Buchbinder, A.4    Zolla-Pazner, S.5
  • 27
    • 0034652565 scopus 로고    scopus 로고
    • Effects of oligomerization on the epitopes of the human immunodeficiency virus type 1 envelope glycoproteins
    • Gorny M.K., VanCott T.C., Williams C., Revesz K., and Zolla-Pazner S. Effects of oligomerization on the epitopes of the human immunodeficiency virus type 1 envelope glycoproteins. Virology 267 (2000) 220-228
    • (2000) Virology , vol.267 , pp. 220-228
    • Gorny, M.K.1    VanCott, T.C.2    Williams, C.3    Revesz, K.4    Zolla-Pazner, S.5
  • 33
    • 0028097964 scopus 로고
    • Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains
    • Kayman S.C., Wu Z., Revesz K., Chen H., Kopelman R., and Pinter A. Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains. J. Virol. 68 (1994) 400-410
    • (1994) J. Virol. , vol.68 , pp. 400-410
    • Kayman, S.C.1    Wu, Z.2    Revesz, K.3    Chen, H.4    Kopelman, R.5    Pinter, A.6
  • 34
    • 11144233210 scopus 로고    scopus 로고
    • Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade A and clade B V3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking
    • Krachmarov C., Pinter A., Honnen W.J., Gorny M.K., Nyambi P.N., Zolla-Pazner S., and Kayman S.C. Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade A and clade B V3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking. J. Virol. 79 (2005) 780-790
    • (2005) J. Virol. , vol.79 , pp. 780-790
    • Krachmarov, C.1    Pinter, A.2    Honnen, W.J.3    Gorny, M.K.4    Nyambi, P.N.5    Zolla-Pazner, S.6    Kayman, S.C.7
  • 35
    • 0032167410 scopus 로고    scopus 로고
    • Molecular characterization of five neutralizing anti-HIV type 1 antibodies: Identification of nonconventional D segments in the human monoclonal antibodies 2G12 and 2F5
    • Kunert R., Ruker F., and Katinger H. Molecular characterization of five neutralizing anti-HIV type 1 antibodies: Identification of nonconventional D segments in the human monoclonal antibodies 2G12 and 2F5. AIDS Res. Hum. Retroviruses 14 (1998) 1115-1128
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1115-1128
    • Kunert, R.1    Ruker, F.2    Katinger, H.3
  • 36
    • 3843139398 scopus 로고    scopus 로고
    • Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody
    • Kunert R., Wolbank S., Stiegler G., Weik R., and Katinger H. Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody. AIDS Res. Hum. Retroviruses 20 (2004) 755-762
    • (2004) AIDS Res. Hum. Retroviruses , vol.20 , pp. 755-762
    • Kunert, R.1    Wolbank, S.2    Stiegler, G.3    Weik, R.4    Katinger, H.5
  • 37
    • 0028882540 scopus 로고
    • Use of a novel mutagenesis strategy, optimized residue substitution, to decrease the off-rate of an anti-gp120 antibody
    • Lewis C.M., Hollis G.F., Mark III G.E., Tung J.S., and Ludmerer S.W. Use of a novel mutagenesis strategy, optimized residue substitution, to decrease the off-rate of an anti-gp120 antibody. Mol. Immunol. 32 (1995) 1065-1072
    • (1995) Mol. Immunol. , vol.32 , pp. 1065-1072
    • Lewis, C.M.1    Hollis, G.F.2    Mark III, G.E.3    Tung, J.S.4    Ludmerer, S.W.5
  • 38
    • 0042872480 scopus 로고    scopus 로고
    • Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120
    • Liu F., Bergami P.L., Duval M., Kuhrt D., Posner M., and Cavacini L. Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120. AIDS Res. Hum. Retroviruses 19 (2003) 597-607
    • (2003) AIDS Res. Hum. Retroviruses , vol.19 , pp. 597-607
    • Liu, F.1    Bergami, P.L.2    Duval, M.3    Kuhrt, D.4    Posner, M.5    Cavacini, L.6
  • 39
    • 0042163216 scopus 로고    scopus 로고
    • Molecular ontogeny of the human antibody repertoire to the Haemophilus influenzae type B polysaccharide: expression of canonical variable regions and their variants in vaccinated infants
    • Lucas A.H., McLean G.R., Reason D.C., O'Connor A.P., Felton M.C., and Moulton K.D. Molecular ontogeny of the human antibody repertoire to the Haemophilus influenzae type B polysaccharide: expression of canonical variable regions and their variants in vaccinated infants. Clin. Immunol. 108 (2003) 119-127
    • (2003) Clin. Immunol. , vol.108 , pp. 119-127
    • Lucas, A.H.1    McLean, G.R.2    Reason, D.C.3    O'Connor, A.P.4    Felton, M.C.5    Moulton, K.D.6
  • 41
    • 0025760317 scopus 로고
    • Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes
    • Marks J.D., Tristem M., Karpas A., and Winter G. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes. Eur. J. Immunol. 21 (1991) 985-991
    • (1991) Eur. J. Immunol. , vol.21 , pp. 985-991
    • Marks, J.D.1    Tristem, M.2    Karpas, A.3    Winter, G.4
  • 42
    • 0027367543 scopus 로고
    • Variable region genes of anti-HIV human monoclonal antibodies: non-restricted use of the V gene repertoire and extensive somatic mutation
    • Moran M.J., Andris J.S., Matsumato Y., Capra J.D., and Hersh E.M. Variable region genes of anti-HIV human monoclonal antibodies: non-restricted use of the V gene repertoire and extensive somatic mutation. Mol. Immunol. 30 (1993) 1543-1551
    • (1993) Mol. Immunol. , vol.30 , pp. 1543-1551
    • Moran, M.J.1    Andris, J.S.2    Matsumato, Y.3    Capra, J.D.4    Hersh, E.M.5
  • 44
    • 0037317611 scopus 로고    scopus 로고
    • Alternative conformations of HIV-1 V3 loops mimic B hairpins in chemokines, suggesting a mechanism for coreceptor selectivity
    • Sharon M., Kessler N., Levy R., Zolla-Pazner S., Gorlach M., and Anglister J. Alternative conformations of HIV-1 V3 loops mimic B hairpins in chemokines, suggesting a mechanism for coreceptor selectivity. Structure (Camb) 11 (2003) 225-236
    • (2003) Structure (Camb) , vol.11 , pp. 225-236
    • Sharon, M.1    Kessler, N.2    Levy, R.3    Zolla-Pazner, S.4    Gorlach, M.5    Anglister, J.6
  • 45
    • 0030221691 scopus 로고    scopus 로고
    • The V4-34 encoded anti-i autoantibodies recognize a large subset of human and mouse B-cells
    • Silberstein L.E., George A., Durdik J.M., and Kipps T.J. The V4-34 encoded anti-i autoantibodies recognize a large subset of human and mouse B-cells. Blood Cells Mol. Dis. 22 (1996) 126-138
    • (1996) Blood Cells Mol. Dis. , vol.22 , pp. 126-138
    • Silberstein, L.E.1    George, A.2    Durdik, J.M.3    Kipps, T.J.4
  • 46
    • 33744933182 scopus 로고    scopus 로고
    • Crystal structures of HIV-1 neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity
    • Stanfield R.L., Gorny M.K., Zolla-Pazner S., and Wilson I.A. Crystal structures of HIV-1 neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J. Virol. 80 (2006) 6093-6105
    • (2006) J. Virol. , vol.80 , pp. 6093-6105
    • Stanfield, R.L.1    Gorny, M.K.2    Zolla-Pazner, S.3    Wilson, I.A.4
  • 47
    • 0033012615 scopus 로고    scopus 로고
    • Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B
    • Sun Y., Park M.K., Kim J., Diamond B., Solomon A., and Nahm M.H. Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B. Infect. Immun. 67 (1999) 1172-1179
    • (1999) Infect. Immun. , vol.67 , pp. 1172-1179
    • Sun, Y.1    Park, M.K.2    Kim, J.3    Diamond, B.4    Solomon, A.5    Nahm, M.H.6
  • 48
    • 0021041087 scopus 로고
    • Construction and testing of mouse-human heteromyelomas for human monoclonal antibody production
    • Teng N.N., Lam K.S., Calvo Riera F., and Kaplan H.S. Construction and testing of mouse-human heteromyelomas for human monoclonal antibody production. Proc. Natl. Acad. Sci. U.S.A. 80 (1983) 7308-7312
    • (1983) Proc. Natl. Acad. Sci. U.S.A. , vol.80 , pp. 7308-7312
    • Teng, N.N.1    Lam, K.S.2    Calvo Riera, F.3    Kaplan, H.S.4
  • 49
    • 0026801056 scopus 로고
    • Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein
    • Thali M., Furman C., Ho D.D., Robinson J., Tilley S., Pinter A., and Sodroski J. Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein. J. Virol. 66 (1992) 5635-5641
    • (1992) J. Virol. , vol.66 , pp. 5635-5641
    • Thali, M.1    Furman, C.2    Ho, D.D.3    Robinson, J.4    Tilley, S.5    Pinter, A.6    Sodroski, J.7
  • 50
    • 0027256814 scopus 로고
    • Characterization of conserved HIV-type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali M., Moore J.P., Furman C., Charles M., Ho D.D., Robinson J., and Sodroski J. Characterization of conserved HIV-type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J. Virol. 67 (1993) 3978-3988
    • (1993) J. Virol. , vol.67 , pp. 3978-3988
    • Thali, M.1    Moore, J.P.2    Furman, C.3    Charles, M.4    Ho, D.D.5    Robinson, J.6    Sodroski, J.7
  • 53
    • 0028609273 scopus 로고
    • Molecular characterization of variable heavy and light chain regions of five HIV type 1-specific human monoclonal antibodies
    • van der Donk E.M., Schutten M., Osterhaus A.D., and van der Heijden R.W. Molecular characterization of variable heavy and light chain regions of five HIV type 1-specific human monoclonal antibodies. AIDS Res. Hum. Retroviruses 10 (1994) 1639-1649
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 1639-1649
    • van der Donk, E.M.1    Schutten, M.2    Osterhaus, A.D.3    van der Heijden, R.W.4
  • 56
    • 0026055421 scopus 로고
    • Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies
    • Xu J.-Y., Gorny M.K., Palker T., Karwowska S., and Zolla-Pazner S. Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodies. J. Virol. 65 (1991) 4832-4838
    • (1991) J. Virol. , vol.65 , pp. 4832-4838
    • Xu, J.-Y.1    Gorny, M.K.2    Palker, T.3    Karwowska, S.4    Zolla-Pazner, S.5
  • 57
    • 0842311270 scopus 로고    scopus 로고
    • Identification of a novel CD4i human monoclonal antibody Fab that neutralizes HIV-1 primary isolates from different clades
    • Zhang M.Y., Shu Y., Sidorov I., and Dimitrov D.S. Identification of a novel CD4i human monoclonal antibody Fab that neutralizes HIV-1 primary isolates from different clades. Antiviral Res. 61 (2004) 161-164
    • (2004) Antiviral Res. , vol.61 , pp. 161-164
    • Zhang, M.Y.1    Shu, Y.2    Sidorov, I.3    Dimitrov, D.S.4
  • 60
    • 0032943087 scopus 로고    scopus 로고
    • Immunotyping of human immunodeficiency virus type 1 (HIV): an approach to immunologic classification of HIV
    • Zolla-Pazner S., Gorny M.K., Nyambi P.N., VanCott T.C., and Nadas A. Immunotyping of human immunodeficiency virus type 1 (HIV): an approach to immunologic classification of HIV. J. Virol. 73 (1999) 4042-4051
    • (1999) J. Virol. , vol.73 , pp. 4042-4051
    • Zolla-Pazner, S.1    Gorny, M.K.2    Nyambi, P.N.3    VanCott, T.C.4    Nadas, A.5


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