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Volumn 1, Issue 2, 2009, Pages 97-112

Natural history of innate host defense peptides

Author keywords

Cathelicidins; Comparative genomics; Defensins; Innate immunity; Molecular timescale; Vertebrate evolution

Indexed keywords


EID: 84877295920     PISSN: 18671306     EISSN: 18671314     Source Type: Journal    
DOI: 10.1007/s12602-009-9031-x     Document Type: Review
Times cited : (6)

References (156)
  • 1
    • 0037391712 scopus 로고    scopus 로고
    • Amoebapores, archaic effector peptides of protozoan origin, are discharged into phagosomes and kill bacteria by permeabilizing their membranes
    • Andra J, Herbst R, Leippe M (2003) Amoebapores, archaic effector peptides of protozoan origin, are discharged into phagosomes and kill bacteria by permeabilizing their membranes. Dev Comp Immunol 27:291-304
    • (2003) Dev Comp Immunol , vol.27 , pp. 291-304
    • Andra, J.1    Herbst, R.2    Leippe, M.3
  • 3
    • 0041703014 scopus 로고    scopus 로고
    • Origins and evolutionary relationships between the innate and the adaptive arms of immune systems
    • Bayne CJ (2003) Origins and evolutionary relationships between the innate and the adaptive arms of immune systems. Integr Comp Biol 43:293-299
    • (2003) Integr Comp Biol , vol.43 , pp. 293-299
    • Bayne, C.J.1
  • 4
    • 0030293667 scopus 로고    scopus 로고
    • Immunity and the invertebrates
    • Beck G, Habicht GS (1996) Immunity and the invertebrates. Sci Am 275:60-66
    • (1996) Sci Am , vol.275 , pp. 60-66
    • Beck, G.1    Habicht, G.S.2
  • 5
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: All we need to know about danger
    • Bianchi ME (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81:1-5
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 7
    • 34247645414 scopus 로고    scopus 로고
    • Mammalian antimicrobial proteins and peptides: Overview on the RNase A superfamily members involved in innate host defence
    • Boix E, Nogues MV (2007) Mammalian antimicrobial proteins and peptides: overview on the RNase A superfamily members involved in innate host defence. Mol Biosyst 3:317-335
    • (2007) Mol Biosyst , vol.3 , pp. 317-335
    • Boix, E.1    Nogues, M.V.2
  • 8
    • 0029415466 scopus 로고
    • The Earth's early evolution
    • Bowring SA, Housh T (1995) The Earth's early evolution. Science 269:1535-1540
    • (1995) Science , vol.269 , pp. 1535-1540
    • Bowring, S.A.1    Housh, T.2
  • 9
    • 30344480252 scopus 로고    scopus 로고
    • A bacterial sensory system that activates resistance to innate immune defenses: Potential targets for antimicrobial therapeutics
    • Brodsky IE, Gunn JS (2005) A bacterial sensory system that activates resistance to innate immune defenses: potential targets for antimicrobial therapeutics. Mol Interv 5:335-337
    • (2005) Mol Interv , vol.5 , pp. 335-337
    • Brodsky, I.E.1    Gunn, J.S.2
  • 10
    • 0141533076 scopus 로고    scopus 로고
    • Dual function of C-type lectin-like receptors in the immune system
    • Cambi A, Figdor CG (2003) Dual function of C-type lectin-like receptors in the immune system. Curr Opin Cell Biol 15:539-546
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 539-546
    • Cambi, A.1    Figdor, C.G.2
  • 11
    • 29944435671 scopus 로고    scopus 로고
    • Two cathelicidin genes are present in both rainbow trout (Oncorhynchus mykiss) and atlantic salmon (Salmo salar)
    • Chang CI, Zhang YA, Zou J, Nie P, Secombes CJ (2006) Two cathelicidin genes are present in both rainbow trout (Oncorhynchus mykiss) and atlantic salmon (Salmo salar). Antimicrob Agents Chemother 50:185-195
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 185-195
    • Chang, C.I.1    Zhang, Y.A.2    Zou, J.3    Nie, P.4    Secombes, C.J.5
  • 12
    • 33745624822 scopus 로고    scopus 로고
    • Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity
    • Chattopadhyay S, Sinha NK, Banerjee S, Roy D, Chattopadhyay D, Roy S (2006) Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity. Proteins 64:524-531
    • (2006) Proteins , vol.64 , pp. 524-531
    • Chattopadhyay, S.1    Sinha, N.K.2    Banerjee, S.3    Roy, D.4    Chattopadhyay, D.5    Roy, S.6
  • 13
    • 27144543751 scopus 로고    scopus 로고
    • Nisin biosynthesis and its properties
    • Cheigh CI, Pyun YR (2005) Nisin biosynthesis and its properties. Biotechnol Lett 27:1641-1648
    • (2005) Biotechnol Lett , vol.27 , pp. 1641-1648
    • Cheigh, C.I.1    Pyun, Y.R.2
  • 14
    • 67649406168 scopus 로고    scopus 로고
    • Buforins: Histone H2Aderived antimicrobial peptides from toad stomach
    • Cho JH, Sung BH, Kim SC (2009) Buforins: histone H2Aderived antimicrobial peptides from toad stomach. Biochim Biophys Acta 1788:1564-1569
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 1564-1569
    • Cho, J.H.1    Sung, B.H.2    Kim, S.C.3
  • 16
    • 67649289909 scopus 로고    scopus 로고
    • Antimicrobial peptides from the skins of North American frogs
    • Conlon JM, Kolodziejek J, Nowotny N (2009) Antimicrobial peptides from the skins of North American frogs. Biochim Biophys Acta 1788:1556-1563
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 1556-1563
    • Conlon, J.M.1    Kolodziejek, J.2    Nowotny, N.3
  • 17
    • 67650451500 scopus 로고    scopus 로고
    • Development of an ELISA for quantification of the antimicrobial peptide piscidin 4 and its application to assess stress in fish
    • Corrales J, Gordon WL, Noga EJ (2009) Development of an ELISA for quantification of the antimicrobial peptide piscidin 4 and its application to assess stress in fish. Fish Shellfish Immunol 27:154-163
    • (2009) Fish Shellfish Immunol , vol.27 , pp. 154-163
    • Corrales, J.1    Gordon, W.L.2    Noga, E.J.3
  • 18
    • 58049206826 scopus 로고    scopus 로고
    • Crosstalk between components of the innate immune system: Promoting anti-microbial defenses and avoiding immunopathologies
    • Crozat K, Vivier E, Dalod M (2009) Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies. Immunol Rev 227:129-149
    • (2009) Immunol Rev , vol.227 , pp. 129-149
    • Crozat, K.1    Vivier, E.2    Dalod, M.3
  • 19
    • 33845675830 scopus 로고    scopus 로고
    • The evolution of immune mechanisms
    • Danilova N (2006) The evolution of immune mechanisms. J Exp Zool B Mol Dev Evol 306:496-520
    • (2006) J Exp Zool B Mol Dev Evol , vol.306 , pp. 496-520
    • Danilova, N.1
  • 21
    • 69249096200 scopus 로고    scopus 로고
    • The roles of antimicrobial peptides in innate host defense
    • Diamond G, Beckloff N, Weinberg A, Kisich KO (2009) The roles of antimicrobial peptides in innate host defense. Curr Pharm Des 15:2377-2392
    • (2009) Curr Pharm Des , vol.15 , pp. 2377-2392
    • Diamond, G.1    Beckloff, N.2    Weinberg, A.3    Kisich, K.O.4
  • 22
    • 0029900207 scopus 로고    scopus 로고
    • Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells
    • Diamond G, Russell JP, Bevins CL (1996) Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells. Proc Natl Acad Sci USA 93:5156-5160
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5156-5160
    • Diamond, G.1    Russell, J.P.2    Bevins, C.L.3
  • 23
    • 84894173739 scopus 로고    scopus 로고
    • Human defensins and LL-37 in mucosal immunity
    • Oct 6 [Epub ahead of print]
    • Doss M, White MR, Tecle T, Hartshorn KL (2009) Human defensins and LL-37 in mucosal immunity. J Leukoc Biol Oct 6 [Epub ahead of print]
    • (2009) J Leukoc Biol
    • Doss, M.1    White, M.R.2    Tecle, T.3    Hartshorn, K.L.4
  • 24
    • 67651161910 scopus 로고    scopus 로고
    • Human defensins as cancer biomarkers and antitumour molecules
    • Droin N, Hendra JB, Ducoroy P, Solary E (2009) Human defensins as cancer biomarkers and antitumour molecules. J Proteomics 72:918-927
    • (2009) J Proteomics , vol.72 , pp. 918-927
    • Droin, N.1    Hendra, J.B.2    Ducoroy, P.3    Solary, E.4
  • 25
    • 64049095240 scopus 로고    scopus 로고
    • TREM and TREM-like receptors in inflammation and disease
    • Ford JW, Mcfficar DW (2009) TREM and TREM-like receptors in inflammation and disease. Curr Opin Immunol 21:38-46
    • (2009) Curr Opin Immunol , vol.21 , pp. 38-46
    • Ford, J.W.1    McFficar, D.W.2
  • 26
    • 0034307802 scopus 로고    scopus 로고
    • Antibacterial and hemolytic activity of the skin of the terrestrial salamander, Plethodon cinereus
    • Fredericks LP, Dankert JR (2000) Antibacterial and hemolytic activity of the skin of the terrestrial salamander, Plethodon cinereus. J Exp Zool 287:340-345
    • (2000) J Exp Zool , vol.287 , pp. 340-345
    • Fredericks, L.P.1    Dankert, J.R.2
  • 27
    • 28444459897 scopus 로고    scopus 로고
    • How Toll-like receptors and Nodlike receptors contribute to innate immunity in mammals
    • Fritz JH, Girardin SE (2005) How Toll-like receptors and Nodlike receptors contribute to innate immunity in mammals. J Endotoxin Res 11:390-394
    • (2005) J Endotoxin Res , vol.11 , pp. 390-394
    • Fritz, J.H.1    Girardin, S.E.2
  • 28
    • 1642463804 scopus 로고    scopus 로고
    • The lectin-complement pathway-its role in innate immunity and evolution
    • Fujita T, Matsushita M, Endo Y (2004) The lectin-complement pathway-its role in innate immunity and evolution. Immunol Rev 198:185-202
    • (2004) Immunol Rev , vol.198 , pp. 185-202
    • Fujita, T.1    Matsushita, M.2    Endo, Y.3
  • 29
    • 16844377323 scopus 로고    scopus 로고
    • Defensins and other antimicrobial peptides: A historical perspective and an update
    • Ganz T (2005) Defensins and other antimicrobial peptides: a historical perspective and an update. Comb Chem High Throughput Screen 8:209-217
    • (2005) Comb Chem High Throughput Screen , vol.8 , pp. 209-217
    • Ganz, T.1
  • 30
    • 0033168860 scopus 로고    scopus 로고
    • Antibiotic peptides from higher eukaryotes: Biology and applications
    • Ganz T, Lehrer RI (1999) Antibiotic peptides from higher eukaryotes: biology and applications. Mol Med Today 5:292-297
    • (1999) Mol Med Today , vol.5 , pp. 292-297
    • Ganz, T.1    Lehrer, R.I.2
  • 32
    • 0032005344 scopus 로고    scopus 로고
    • Antimicrobial peptides of vertebrates
    • Ganz T, Lehrer RI (1998) Antimicrobial peptides of vertebrates. Curr Opin Immunol 10:41-44
    • (1998) Curr Opin Immunol , vol.10 , pp. 41-44
    • Ganz, T.1    Lehrer, R.I.2
  • 34
    • 0030861378 scopus 로고    scopus 로고
    • Antimicrobial peptides of phagocytes and epithelia
    • Ganz T, Weiss J (1997) Antimicrobial peptides of phagocytes and epithelia. Semin Hematol 34:343-354
    • (1997) Semin Hematol , vol.34 , pp. 343-354
    • Ganz, T.1    Weiss, J.2
  • 35
  • 36
    • 0033973411 scopus 로고    scopus 로고
    • Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens
    • Goraya J, Wang Y, Li Z, O'Flaherty M, Knoop FC, Platz JE, Conlon JM (2000) Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. Eur J Biochem 267:894-900
    • (2000) Eur J Biochem , vol.267 , pp. 894-900
    • Goraya, J.1    Wang, Y.2    Li, Z.3    O'Flaherty, M.4    Knoop, F.C.5    Platz, J.E.6    Conlon, J.M.7
  • 37
    • 0037184995 scopus 로고    scopus 로고
    • Pattern recognition receptors: Doubling up for the innate immune response
    • Gordon S (2002) Pattern recognition receptors: doubling up for the innate immune response. Cell 111:927-930
    • (2002) Cell , vol.111 , pp. 927-930
    • Gordon, S.1
  • 39
    • 33644852494 scopus 로고    scopus 로고
    • Characterization of a defensin from the oyster Crassostrea gigas. Recombinant production, folding, solution structure, antimicrobial activities, and gene expression
    • Gueguen Y, Herpin A, Aumelas A, Garnier J, Fievet J, Escoubas JM, Bulet P, Gonzalez M, Lelong C, Favrel P, Bachere E (2006) Characterization of a defensin from the oyster Crassostrea gigas. Recombinant production, folding, solution structure, antimicrobial activities, and gene expression. J Biol Chem 281:313-323
    • (2006) J Biol Chem , vol.281 , pp. 313-323
    • Gueguen, Y.1    Herpin, A.2    Aumelas, A.3    Garnier, J.4    Fievet, J.5    Escoubas, J.M.6    Bulet, P.7    Gonzalez, M.8    Lelong, C.9    Favrel, P.10    Bachere, E.11
  • 40
    • 33845699790 scopus 로고    scopus 로고
    • Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
    • Hancock RE, Sahl HG (2006) Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 24:1551-1557
    • (2006) Nat Biotechnol , vol.24 , pp. 1551-1557
    • Hancock, R.E.1    Sahl, H.G.2
  • 43
    • 0036167107 scopus 로고    scopus 로고
    • Drosophila innate immunity: An evolutionary perspective
    • Hoffmann JA, Reichhart JM (2002) Drosophila innate immunity: an evolutionary perspective. Nat Immunol 3:121-126
    • (2002) Nat Immunol , vol.3 , pp. 121-126
    • Hoffmann, J.A.1    Reichhart, J.M.2
  • 46
    • 0033214579 scopus 로고    scopus 로고
    • Evolutionary diversification of the mammalian defensins
    • Hughes AL (1999) Evolutionary diversification of the mammalian defensins. Cell Mol Life Sci 56:94-103
    • (1999) Cell Mol Life Sci , vol.56 , pp. 94-103
    • Hughes, A.L.1
  • 47
    • 0030990203 scopus 로고    scopus 로고
    • Coordinated amino acid changes in the evolution of mammalian defensins
    • Hughes AL, Yeager M (1997) Coordinated amino acid changes in the evolution of mammalian defensins. J Mol Evol 44:675-682
    • (1997) J Mol Evol , vol.44 , pp. 675-682
    • Hughes, A.L.1    Yeager, M.2
  • 50
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti TD, Lamkanfi M, Nunez G (2007) Intracellular NOD-like receptors in host defense and disease. Immunity 27:549-559
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 51
    • 34548716455 scopus 로고    scopus 로고
    • Microbial oceanography: Paradigms, processes and promise
    • Karl DM (2007) Microbial oceanography: paradigms, processes and promise. Nat Rev Microbiol 5:759-769
    • (2007) Nat Rev Microbiol , vol.5 , pp. 759-769
    • Karl, D.M.1
  • 52
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like receptor and RIG-I-like receptor signaling
    • Kawai T, Akira S (2008) Toll-like receptor and RIG-I-like receptor signaling. Ann NY Acad Sci 1143:1-20
    • (2008) Ann NY Acad Sci , vol.1143 , pp. 1-20
    • Kawai, T.1    Akira, S.2
  • 53
    • 63649108380 scopus 로고    scopus 로고
    • The roles of TLRs, RLRs and NLRs in pathogen recognition
    • Kawai T, Akira S (2009) The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 21:317-337
    • (2009) Int Immunol , vol.21 , pp. 317-337
    • Kawai, T.1    Akira, S.2
  • 55
    • 33846316333 scopus 로고    scopus 로고
    • The TREM receptor family and signal integration
    • Klesney-Tait J, Turnbull IR, Colonna M (2006) The TREM receptor family and signal integration. Nat Immunol 7:1266-1273
    • (2006) Nat Immunol , vol.7 , pp. 1266-1273
    • Klesney-Tait, J.1    Turnbull, I.R.2    Colonna, M.3
  • 56
    • 84894236121 scopus 로고    scopus 로고
    • at Harvard University
    • Knoll, AH (2003) Paleontology & geobiology at Harvard University http://www.fas.harvard.edu/*knollgrp/research.htm
    • (2003) Paleontology & geobiology
    • Knoll, A.H.1
  • 57
    • 54949142477 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of antimicrobial proteins
    • Kolls JK, McCray PB Jr, Chan YR (2008) Cytokine-mediated regulation of antimicrobial proteins. Nat Rev Immunol 8:829-835
    • (2008) Nat Rev Immunol , vol.8 , pp. 829-835
    • Kolls, J.K.1    McCray Jr., P.B.2    Chan, Y.R.3
  • 58
    • 33845431988 scopus 로고    scopus 로고
    • RNA-and virus-independent inhibition of antiviral signaling by RNA helicase LGP2
    • Komuro A, Horvath CM (2006) RNA-and virus-independent inhibition of antiviral signaling by RNA helicase LGP2. J Virol 80:12332-12342
    • (2006) J Virol , vol.80 , pp. 12332-12342
    • Komuro, A.1    Horvath, C.M.2
  • 59
    • 0036136328 scopus 로고    scopus 로고
    • Regulation of human beta-defensin-2 in gingival epithelial cells: The involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family
    • Krisanaprakornkit S, Kimball JR, Dale BA (2002) Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family. J Immunol 168:316-324
    • (2002) J Immunol , vol.168 , pp. 316-324
    • Krisanaprakornkit, S.1    Kimball, J.R.2    Dale, B.A.3
  • 62
    • 0032580152 scopus 로고    scopus 로고
    • A molecular timescale for vertebrate evolution
    • Kumar S, Hedges SB (1998) A molecular timescale for vertebrate evolution. Nature 392:917-920
    • (1998) Nature , vol.392 , pp. 917-920
    • Kumar, S.1    Hedges, S.B.2
  • 64
    • 3142779216 scopus 로고    scopus 로고
    • Solution structure of spheniscin, a beta-defensin from the penguin stomach
    • Landon C, Thouzeau C, Labbe H, Bulet P, Vovelle F (2004) Solution structure of spheniscin, a beta-defensin from the penguin stomach. J Biol Chem 279:30433-30439
    • (2004) J Biol Chem , vol.279 , pp. 30433-30439
    • Landon, C.1    Thouzeau, C.2    Labbe, H.3    Bulet, P.4    Vovelle, F.5
  • 66
    • 42549115652 scopus 로고    scopus 로고
    • PRRDB: A comprehensive database of pattern-recognition receptors and their ligands
    • Lata S, Raghava GP (2008) PRRDB: a comprehensive database of pattern-recognition receptors and their ligands. BMC Genomics 9:180
    • (2008) BMC Genomics , vol.9 , pp. 180
    • Lata, S.1    Raghava, G.P.2
  • 67
    • 33750949541 scopus 로고    scopus 로고
    • Linking immune defenses and life history at the levels of the individual and the species
    • Lee KA (2006) Linking immune defenses and life history at the levels of the individual and the species. Integr Comp Biol 46(6):1000-1015
    • (2006) Integr Comp Biol , vol.46 , Issue.6 , pp. 1000-1015
    • Lee, K.A.1
  • 68
    • 0002504117 scopus 로고
    • Defensins and protegrins: Vertebrate analogues of arthropod antimicrobial peptides
    • In: Hoffman J, Janeway C Jr, Natori S (eds), R.G. Landes Company, Austin
    • Lehrer R, Harwig S, Ganz T (1994) Defensins and protegrins: vertebrate analogues of arthropod antimicrobial peptides. In: Hoffman J, Janeway C Jr, Natori S (eds) Phylogenetic perspectives in immunity: the insect host defense. R.G. Landes Company, Austin, pp 19-29
    • (1994) Phylogenetic perspectives in immunity: The insect host defense , pp. 19-29
    • Lehrer, R.1    Harwig, S.2    Ganz, T.3
  • 69
    • 34047268684 scopus 로고    scopus 로고
    • The host defense of Drosophila melanogaster
    • Lemaitre B, Hoffmann J (2007) The host defense of Drosophila melanogaster. Annu Rev Immunol 25:697-743
    • (2007) Annu Rev Immunol , vol.25 , pp. 697-743
    • Lemaitre, B.1    Hoffmann, J.2
  • 71
    • 33845595623 scopus 로고    scopus 로고
    • Innate immunity and inflammation-New frontiers in comparative cardiovascular pathology
    • Linde A, Mosier D, Blecha F, Melgarejo T (2007) Innate immunity and inflammation-New frontiers in comparative cardiovascular pathology. Cardiovasc Res 73:26-36
    • (2007) Cardiovasc Res , vol.73 , pp. 26-36
    • Linde, A.1    Mosier, D.2    Blecha, F.3    Melgarejo, T.4
  • 73
    • 0030292686 scopus 로고    scopus 로고
    • Sharks and the origins of vertebrate immunity
    • Litman GW (1996) Sharks and the origins of vertebrate immunity. Sci Am 275:67-71
    • (1996) Sci Am , vol.275 , pp. 67-71
    • Litman, G.W.1
  • 74
    • 67649392454 scopus 로고    scopus 로고
    • Preface to amphibian antimicrobial peptides
    • Mangoni ML (2009) Preface to amphibian antimicrobial peptides. Biochim Biophys Acta 1788:1535-1536
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 1535-1536
    • Mangoni, M.L.1
  • 75
    • 0344412954 scopus 로고    scopus 로고
    • Ranacyclins, a new family of short cyclic antimicrobial peptides: Biological function, mode of action, and parameters involved in target specificity
    • Mangoni ML, Papo N, Mignogna G, Andreu D, Shai Y, Barra D, Simmaco M (2003) Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity. Biochemistry 42:14023-14035
    • (2003) Biochemistry , vol.42 , pp. 14023-14035
    • Mangoni, M.L.1    Papo, N.2    Mignogna, G.3    Andreu, D.4    Shai, Y.5    Barra, D.6    Simmaco, M.7
  • 78
    • 0032693639 scopus 로고    scopus 로고
    • Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes
    • Matsuzaki K (1999) Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. Biochim Biophys Acta 1462:1-10
    • (1999) Biochim Biophys Acta , vol.1462 , pp. 1-10
    • Matsuzaki, K.1
  • 79
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P (1994) Tolerance, danger, and the extended family. Annu Rev Immunol 12:991-1045
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 81
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E, Tschopp J, Karin M (2006) Intracellular pattern recognition receptors in the host response. Nature 442:39-44
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 83
    • 46949102571 scopus 로고    scopus 로고
    • Structure and function of LGP2, a DEX(D/ H) helicase that regulates the innate immunity response
    • Murali A, Li X, Ranjith-Kumar CT, Bhardwaj K, Holzenburg A, Li P, Kao CC (2008) Structure and function of LGP2, a DEX(D/ H) helicase that regulates the innate immunity response. J Biol Chem 283:15825-15833
    • (2008) J Biol Chem , vol.283 , pp. 15825-15833
    • Murali, A.1    Li, X.2    Ranjith-Kumar, C.T.3    Bhardwaj, K.4    Holzenburg, A.5    Li, P.6    Kao, C.C.7
  • 85
    • 33846991985 scopus 로고    scopus 로고
    • Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins
    • Nair DG, Fry BG, Alewood P, Kumar PP, Kini RM (2007) Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins. Biochem J 402:93-104
    • (2007) Biochem J , vol.402 , pp. 93-104
    • Nair, D.G.1    Fry, B.G.2    Alewood, P.3    Kumar, P.P.4    Kini, R.M.5
  • 86
    • 1042302158 scopus 로고    scopus 로고
    • Evolution of primate theta-defensins: A serpentine path to a sweet tooth
    • Nguyen TX, Cole AM, Lehrer RI (2003) Evolution of primate theta-defensins: a serpentine path to a sweet tooth. Peptides 24:1647-1654
    • (2003) Peptides , vol.24 , pp. 1647-1654
    • Nguyen, T.X.1    Cole, A.M.2    Lehrer, R.I.3
  • 87
    • 1042290515 scopus 로고    scopus 로고
    • Molecular strategies in biological evolution of antimicrobial peptides
    • Nicolas P, Vanhoye D, Amiche M (2003) Molecular strategies in biological evolution of antimicrobial peptides. Peptides 24:1669-1680
    • (2003) Peptides , vol.24 , pp. 1669-1680
    • Nicolas, P.1    Vanhoye, D.2    Amiche, M.3
  • 88
    • 77950973496 scopus 로고    scopus 로고
    • Host defence peptides: Antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections
    • Nijnik A, Hancock REW (2009) Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections. Emerg Health Threats J 2(e1):1-7
    • (2009) Emerg Health Threats J , vol.2 , Issue.E1 , pp. 1-7
    • Nijnik, A.1    Hancock, R.E.W.2
  • 89
    • 0037595568 scopus 로고    scopus 로고
    • Piscidins: A novel family of peptide antibiotics from fish
    • Noga EJ, Silphaduang U (2003) Piscidins: a novel family of peptide antibiotics from fish. Drug News Perspect 16:87-92
    • (2003) Drug News Perspect , vol.16 , pp. 87-92
    • Noga, E.J.1    Silphaduang, U.2
  • 90
    • 0142218765 scopus 로고    scopus 로고
    • Roles of antimicrobial peptides such as defensins in innate and adaptive immunity
    • Oppenheim JJ, Biragyn A, Kwak LW, Yang D (2003) Roles of antimicrobial peptides such as defensins in innate and adaptive immunity. Ann Rheum Dis 62(Suppl 2):ii17-ii21
    • (2003) Ann Rheum Dis , vol.62 , Issue.SUPPL. 2
    • Oppenheim, J.J.1    Biragyn, A.2    Kwak, L.W.3    Yang, D.4
  • 92
    • 0038667888 scopus 로고    scopus 로고
    • Innate immunity: The unsung heroes
    • Parham P (2003) Innate immunity: the unsung heroes. Nature 423:20
    • (2003) Nature , vol.423 , pp. 20
    • Parham, P.1
  • 93
    • 14644435363 scopus 로고    scopus 로고
    • Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes
    • Patil A, Hughes AL, Zhang G (2004) Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes. Physiol Genomics 20:1-11
    • (2004) Physiol Genomics , vol.20 , pp. 1-11
    • Patil, A.1    Hughes, A.L.2    Zhang, G.3
  • 94
    • 33645469217 scopus 로고    scopus 로고
    • Crossspecies analysis of the mammalian beta-defensin gene family: Presence of syntenic gene clusters and preferential expression in the male reproductive tract
    • Patil AA, Cai Y, Sang Y, Blecha F, Zhang G (2005) Crossspecies analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol Genomics 23:5-17
    • (2005) Physiol Genomics , vol.23 , pp. 5-17
    • Patil, A.A.1    Cai, Y.2    Sang, Y.3    Blecha, F.4    Zhang, G.5
  • 96
    • 33645834508 scopus 로고    scopus 로고
    • Experimental evolution of resistance to an antimicrobial peptide
    • Perron GG, Zasloff M, Bell G (2006) Experimental evolution of resistance to an antimicrobial peptide. Proc Biol Sci 273:251-256
    • (2006) Proc Biol Sci , vol.273 , pp. 251-256
    • Perron, G.G.1    Zasloff, M.2    Bell, G.3
  • 97
    • 0036532403 scopus 로고    scopus 로고
    • How do bacteria resist human antimicrobial peptides?
    • Peschel A (2002) How do bacteria resist human antimicrobial peptides? Trends Microbiol 10:179-186
    • (2002) Trends Microbiol , vol.10 , pp. 179-186
    • Peschel, A.1
  • 98
    • 36749100831 scopus 로고    scopus 로고
    • The success of the RNase scaffold in the advance of biosciences and in evolution
    • Pizzo E, D'Alessio G (2007) The success of the RNase scaffold in the advance of biosciences and in evolution. Gene 406:8-12
    • (2007) Gene , vol.406 , pp. 8-12
    • Pizzo, E.1    D'Alessio, G.2
  • 99
    • 0346335808 scopus 로고    scopus 로고
    • Immune activation: Death, danger and dendritic cells
    • Pulendran B (2004) Immune activation: death, danger and dendritic cells. Curr Biol 14:R30-R32
    • (2004) Curr Biol , vol.14
    • Pulendran, B.1
  • 101
    • 44649149642 scopus 로고    scopus 로고
    • RNase A ribonucleases and host defense: An evolving story
    • Rosenberg HF (2008) RNase A ribonucleases and host defense: an evolving story. J Leukoc Biol 83:1079-1087
    • (2008) J Leukoc Biol , vol.83 , pp. 1079-1087
    • Rosenberg, H.F.1
  • 102
    • 71549148798 scopus 로고    scopus 로고
    • Tuning the properties of the bacterial membrane with aminoacylated phosphatidylglycerol
    • Roy H (2009) Tuning the properties of the bacterial membrane with aminoacylated phosphatidylglycerol. IUBMB Life 61:940-953
    • (2009) IUBMB Life , vol.61 , pp. 940-953
    • Roy, H.1
  • 104
    • 62249177710 scopus 로고    scopus 로고
    • Antimicrobial peptides and bacteriocins: Alternatives to traditional antibiotics
    • Sang Y, Blecha F (2008) Antimicrobial peptides and bacteriocins: alternatives to traditional antibiotics. Anim Health Res Rev. 9:227-235
    • (2008) Anim Health Res Rev. , vol.9 , pp. 227-235
    • Sang, Y.1    Blecha, F.2
  • 105
    • 57149115580 scopus 로고    scopus 로고
    • Porcine host defense peptides: Expanding repertoire and functions
    • Sang Y, Blecha F (2009) Porcine host defense peptides: expanding repertoire and functions. Dev Comp Immunol 33:334-343
    • (2009) Dev Comp Immunol , vol.33 , pp. 334-343
    • Sang, Y.1    Blecha, F.2
  • 106
    • 17644363748 scopus 로고    scopus 로고
    • Molecular cloning and characterization of three beta-defensins from canine testes
    • Sang Y, Ortega MT, Blecha F, Prakash O, Melgarejo T (2005) Molecular cloning and characterization of three beta-defensins from canine testes. Infect Immun 73:2611-2620
    • (2005) Infect Immun , vol.73 , pp. 2611-2620
    • Sang, Y.1    Ortega, M.T.2    Blecha, F.3    Prakash, O.4    Melgarejo, T.5
  • 109
    • 0032717886 scopus 로고    scopus 로고
    • Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides
    • Shai Y (1999) Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochim Biophys Acta 1462:55-70
    • (1999) Biochim Biophys Acta , vol.1462 , pp. 55-70
    • Shai, Y.1
  • 110
    • 0030456227 scopus 로고    scopus 로고
    • Ecological immunology: Costly parasite defences and trade-offs in evolutionary ecology
    • Sheldon BC, Verhulst S (1996) Ecological immunology: costly parasite defences and trade-offs in evolutionary ecology. Trends Ecol Evol 11(8):317-321
    • (1996) Trends Ecol Evol , vol.11 , Issue.8 , pp. 317-321
    • Sheldon, B.C.1    Verhulst, S.2
  • 111
    • 33746021126 scopus 로고    scopus 로고
    • Hepcidins in amphibians and fishes: Antimicrobial peptides or iron-regulatory hormones?
    • Shi J, Camus AC (2006) Hepcidins in amphibians and fishes: antimicrobial peptides or iron-regulatory hormones? Dev Comp Immunol 30:746-755
    • (2006) Dev Comp Immunol , vol.30 , pp. 746-755
    • Shi, J.1    Camus, A.C.2
  • 112
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y, Evans JE, Rock KL (2003) Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425:516-521
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 113
    • 84894235766 scopus 로고
    • Theories of acquired immunity
    • In: Silverstein A (ed), Academic Press, Inc., San Diego
    • Silverstein A (1989) Theories of acquired immunity. In: Silverstein A (ed) A history of immunology. Academic Press, Inc., San Diego, pp 1-23
    • (1989) A history of immunology , pp. 1-23
    • Silverstein, A.1
  • 114
    • 67650735607 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and arterial thrombosis: Role of the scavenger receptor CD36
    • Silverstein RL (2009) Inflammation, atherosclerosis, and arterial thrombosis: role of the scavenger receptor CD36. Cleve Clin J Med 76(Suppl 2):S27-S30
    • (2009) Cleve Clin J Med , vol.76 , Issue.SUPPL. 2
    • Silverstein, R.L.1
  • 115
    • 67349133120 scopus 로고    scopus 로고
    • Discovery of Anas platyrhynchos avian beta-defensin 2 (Apl_AvBD2) with antibacterial and chemotactic functions
    • Soman SS, Arathy DS, Sreekumar E (2009) Discovery of Anas platyrhynchos avian beta-defensin 2 (Apl_AvBD2) with antibacterial and chemotactic functions. Mol Immunol 46:2029-2038
    • (2009) Mol Immunol , vol.46 , pp. 2029-2038
    • Soman, S.S.1    Arathy, D.S.2    Sreekumar, E.3
  • 117
    • 0019386682 scopus 로고
    • Sequence and specificity of two antibacterial proteins involved in insect immunity
    • Steiner H, Hultmark D, Engstrom A, Bennich H, Boman HG (1981) Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292:246-248
    • (1981) Nature , vol.292 , pp. 246-248
    • Steiner, H.1    Hultmark, D.2    Engstrom, A.3    Bennich, H.4    Boman, H.G.5
  • 120
    • 67449149809 scopus 로고    scopus 로고
    • Animal antimicrobial peptides: Ancient players in innate immunity
    • Strominger JL (2009) Animal antimicrobial peptides: ancient players in innate immunity. J Immunol 182:6633-6634
    • (2009) J Immunol , vol.182 , pp. 6633-6634
    • Strominger, J.L.1
  • 121
    • 4544277845 scopus 로고    scopus 로고
    • Avian antimicrobial peptides: The defense role of beta-defensins
    • Sugiarto H, Yu PL (2004) Avian antimicrobial peptides: the defense role of beta-defensins. Biochem Biophys Res Commun 323:721-727
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 721-727
    • Sugiarto, H.1    Yu, P.L.2
  • 122
    • 34548792911 scopus 로고    scopus 로고
    • Marine viruses-major players in the global ecosystem
    • Suttle CA (2007) Marine viruses-major players in the global ecosystem. Nat Rev Microbiol 5:801-812
    • (2007) Nat Rev Microbiol , vol.5 , pp. 801-812
    • Suttle, C.A.1
  • 123
    • 0033569410 scopus 로고    scopus 로고
    • A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins
    • Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME (1999) A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science 286:498-502
    • (1999) Science , vol.286 , pp. 498-502
    • Tang, Y.Q.1    Yuan, J.2    Osapay, G.3    Osapay, K.4    Tran, D.5    Miller, C.J.6    Ouellette, A.J.7    Selsted, M.E.8
  • 125
    • 0346435102 scopus 로고    scopus 로고
    • Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus
    • Thouzeau C, Le MY, Froget G, Sabatier L, Le BC, Hoffmann JA, Bulet P (2003) Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus. J Biol Chem 278:51053-51058
    • (2003) J Biol Chem , vol.278 , pp. 51053-51058
    • Thouzeau, C.1    Le, M.Y.2    Froget, G.3    Sabatier, L.4    Le, B.C.5    Hoffmann, J.A.6    Bulet, P.7
  • 126
    • 13844322065 scopus 로고    scopus 로고
    • The cathelicidins-structure, function and evolution
    • Tomasinsig L, Zanetti M (2005) The cathelicidins-structure, function and evolution. Curr Protein Pept Sci 6:23-34
    • (2005) Curr Protein Pept Sci , vol.6 , pp. 23-34
    • Tomasinsig, L.1    Zanetti, M.2
  • 127
    • 0036257512 scopus 로고    scopus 로고
    • Molecular diversity in gene-encoded, cationic antimicrobial polypeptides
    • Tossi A, Sandri L (2002) Molecular diversity in gene-encoded, cationic antimicrobial polypeptides. Curr Pharm Des 8:743-761
    • (2002) Curr Pharm Des , vol.8 , pp. 743-761
    • Tossi, A.1    Sandri, L.2
  • 128
    • 84894233243 scopus 로고
    • The historical background to cellular evolution
    • In: Tribe M, Morgan A, Whittaker P (eds), Edwards Arnold Limited, London
    • Tribe M, Morgan A, Whittaker P (1981) The historical background to cellular evolution. In: Tribe M, Morgan A, Whittaker P (eds) The evolution of eukaryotic cells. Edwards Arnold Limited, London, pp 1-15
    • (1981) The evolution of eukaryotic cells , pp. 1-15
    • Tribe, M.1    Morgan, A.2    Whittaker, P.3
  • 129
    • 34548550594 scopus 로고    scopus 로고
    • Collaboration between the innate immune receptors dectin-1, TLRs, and Nods
    • Underhill DM (2007) Collaboration between the innate immune receptors dectin-1, TLRs, and Nods. Immunol Rev 219:75-87
    • (2007) Immunol Rev , vol.219 , pp. 75-87
    • Underhill, D.M.1
  • 130
    • 1042290514 scopus 로고    scopus 로고
    • Hagfish intestinal antimicrobial peptides are ancient cathelicidins
    • Uzzell T, Stolzenberg ED, Shinnar AE, Zasloff M (2003) Hagfish intestinal antimicrobial peptides are ancient cathelicidins. Peptides 24:1655-1667
    • (2003) Peptides , vol.24 , pp. 1655-1667
    • Uzzell, T.1    Stolzenberg, E.D.2    Shinnar, A.E.3    Zasloff, M.4
  • 131
    • 0002027029 scopus 로고
    • A new evolutionary law
    • Van Valen L (1973) A new evolutionary law. Evol Theory 1(1):1-30
    • (1973) Evol Theory , vol.1 , Issue.1 , pp. 1-30
    • Van Valen, L.1
  • 133
    • 33846051382 scopus 로고    scopus 로고
    • Tool developments for structure-function studies of host defense peptides
    • Wang G (2007) Tool developments for structure-function studies of host defense peptides. Protein Pept Lett 14:57-69
    • (2007) Protein Pept Lett , vol.14 , pp. 57-69
    • Wang, G.1
  • 135
    • 0014669335 scopus 로고
    • New concepts of kingdoms or organisms. Evolutionary relations are better represented by new classifications than by the traditional two kingdoms
    • Whittaker RH (1969) New concepts of kingdoms or organisms. Evolutionary relations are better represented by new classifications than by the traditional two kingdoms. Science 163:150-160
    • (1969) Science , vol.163 , pp. 150-160
    • Whittaker, R.H.1
  • 136
    • 0017956171 scopus 로고
    • Protist classification and the kingdoms of organisms
    • Whittaker RH, Margulis L (1978) Protist classification and the kingdoms of organisms. Biosystems 10:3-18
    • (1978) Biosystems , vol.10 , pp. 3-18
    • Whittaker, R.H.1    Margulis, L.2
  • 139
    • 2342559084 scopus 로고    scopus 로고
    • Some scaling principles for the immune system
    • Wiegel FW, Perelson AS (2004) Some scaling principles for the immune system. Immunol Cell Biol 82:127-131
    • (2004) Immunol Cell Biol , vol.82 , pp. 127-131
    • Wiegel, F.W.1    Perelson, A.S.2
  • 140
    • 0025300402 scopus 로고
    • Towards a natural system of organisms: Proposal for the domains Archaea, Bacteria, and Eucarya
    • Woese CR, Kandler O, Wheelis ML (1990) Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya. Proc Natl Acad Sci USA 87:4576-4579
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4576-4579
    • Woese, C.R.1    Kandler, O.2    Wheelis, M.L.3
  • 141
    • 33646367203 scopus 로고    scopus 로고
    • Identification and functional characterization of three chicken cathelicidins with potent antimicrobial activity
    • Xiao Y, Cai Y, Bommineni YR, Fernando SC, Prakash O, Gilliland SE, Zhang G (2006) Identification and functional characterization of three chicken cathelicidins with potent antimicrobial activity. J Biol Chem 281:2858-2867
    • (2006) J Biol Chem , vol.281 , pp. 2858-2867
    • Xiao, Y.1    Cai, Y.2    Bommineni, Y.R.3    Fernando, S.C.4    Prakash, O.5    Gilliland, S.E.6    Zhang, G.7
  • 142
    • 9144261231 scopus 로고    scopus 로고
    • A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: Implications for the origin and evolution of mammalian defensins
    • Xiao Y, Hughes AL, Ando J, Matsuda Y, Cheng JF, Skinner-Noble D, Zhang G (2004) A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins. BMC Genomics 5:56
    • (2004) BMC Genomics , vol.5 , pp. 56
    • Xiao, Y.1    Hughes, A.L.2    Ando, J.3    Matsuda, Y.4    Cheng, J.F.5    Skinner-Noble, D.6    Zhang, G.7
  • 143
    • 0036606951 scopus 로고    scopus 로고
    • Mammalian defensins in immunity: More than just microbicidal
    • Yang D, Biragyn A, Kwak LW, Oppenheim JJ (2002) Mammalian defensins in immunity: more than just microbicidal. Trends Immunol 23:291-296
    • (2002) Trends Immunol , vol.23 , pp. 291-296
    • Yang, D.1    Biragyn, A.2    Kwak, L.W.3    Oppenheim, J.J.4
  • 145
    • 67651101168 scopus 로고    scopus 로고
    • Alarmins and antimicrobial immunity
    • Yang D, Oppenheim JJ (2009) Alarmins and antimicrobial immunity. Med Mycol 47(Suppl 1):S146-S153
    • (2009) Med Mycol , vol.47 , Issue.SUPPL. 1
    • Yang, D.1    Oppenheim, J.J.2
  • 146
    • 0033798839 scopus 로고    scopus 로고
    • Crystallization of antimicrobial pores in membranes: Magainin and protegrin
    • Yang L, Weiss TM, Lehrer RI, Huang HW (2000) Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys J 79:2002-2009
    • (2000) Biophys J , vol.79 , pp. 2002-2009
    • Yang, L.1    Weiss, T.M.2    Lehrer, R.I.3    Huang, H.W.4
  • 147
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
    • Zanetti M, Gennaro R, Romeo D (1995) Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 374:1-5
    • (1995) FEBS Lett , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 148
    • 0009638436 scopus 로고
    • Antibacterial molecules from frogs, sharks and man
    • In: Hoffmann J, Janeway C Jr, Natori S (eds), R.G. Landes Company, Austin
    • Zasloff M (1994) Antibacterial molecules from frogs, sharks and man. In: Hoffmann J, Janeway C Jr, Natori S (eds) Phylogenetic perspectives in immunity: the insect host defense. R.G. Landes Company, Austin, pp 31-41
    • (1994) Phylogenetic perspectives in immunity: The insect host defense , pp. 31-41
    • Zasloff, M.1
  • 149
    • 2042513493 scopus 로고
    • Magainins, a class of antimicrobial peptides from Xenopus skin: Isolation, characterization of two active forms, and partial cDNA sequence of a precursor
    • Zasloff M (1987) Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci USA 84:5449-5453
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5449-5453
    • Zasloff, M.1
  • 151
    • 0034184327 scopus 로고    scopus 로고
    • Porcine antimicrobial peptides: New prospects for ancient molecules of host defense
    • Zhang G, Ross CR, Blecha F (2000) Porcine antimicrobial peptides: new prospects for ancient molecules of host defense. Vet Res 31:277-296
    • (2000) Vet Res , vol.31 , pp. 277-296
    • Zhang, G.1    Ross, C.R.2    Blecha, F.3
  • 152
    • 62249085503 scopus 로고    scopus 로고
    • Host defense peptides for use as potential therapeutics
    • Zhang L, Falla TJ (2009) Host defense peptides for use as potential therapeutics. Curr Opin Investig Drugs 10:164-171
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 164-171
    • Zhang, L.1    Falla, T.J.2
  • 153
    • 52049112301 scopus 로고    scopus 로고
    • Identification and characterization of novel reptile cathelicidins from elapid snakes
    • Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y (2008) Identification and characterization of novel reptile cathelicidins from elapid snakes. Peptides 29:1685-1691
    • (2008) Peptides , vol.29 , pp. 1685-1691
    • Zhao, H.1    Gan, T.X.2    Liu, X.D.3    Jin, Y.4    Lee, W.H.5    Shen, J.H.6    Zhang, Y.7
  • 154
    • 36849005963 scopus 로고    scopus 로고
    • Evidence for myxobacterial origin of eukaryotic defensins
    • Zhu S (2007) Evidence for myxobacterial origin of eukaryotic defensins. Immunogenetics 59:949-954
    • (2007) Immunogenetics , vol.59 , pp. 949-954
    • Zhu, S.1
  • 155
    • 34848836028 scopus 로고    scopus 로고
    • Discovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins
    • Zhu S (2008) Discovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSalphabeta defensins. Mol Immunol 45:828-838
    • (2008) Mol Immunol , vol.45 , pp. 828-838
    • Zhu, S.1
  • 156
    • 66249094862 scopus 로고    scopus 로고
    • Origin and evolution of the RIG-I like RNA helicase gene family
    • Zou J, Chang M, Nie P, Secombes CJ (2009) Origin and evolution of the RIG-I like RNA helicase gene family. BMC Evol Biol 9:85
    • (2009) BMC Evol Biol , vol.9 , pp. 85
    • Zou, J.1    Chang, M.2    Nie, P.3    Secombes, C.J.4


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