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Volumn 2013, Issue , 2013, Pages

From notochord formation to hereditary chordoma: The many roles of brachyury

Author keywords

[No Author keywords available]

Indexed keywords

BRACHYURY PROTEIN; CETUXIMAB; EPITHELIAL MEMBRANE ANTIGEN; ERLOTINIB; FIBROBLAST GROWTH FACTOR; GEFITINIB; IMATINIB; PROTEIN S 100; PROTEOCHONDROITIN SULFATE; RAPAMYCIN; RUBITECAN; SMAD PROTEIN; SUNITINIB; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VIMENTIN; FETOPROTEIN; T BOX TRANSCRIPTION FACTOR;

EID: 84877275234     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/826435     Document Type: Review
Times cited : (84)

References (181)
  • 1
    • 0035141448 scopus 로고    scopus 로고
    • Chordoma: Incidence and survival patterns in the United States, 1973-1995
    • DOI 10.1023/A:1008947301735
    • McMaster M. L., Goldstein A. M., Bromley C. M., Ishibe N., Parry D. M., Chordoma: incidence and survival patterns in the United States, 1973-1995. Cancer Causes and Control 2001 12 1 1 11 2-s2.0-0035141448 10.1023/A: 1008947301735 (Pubitemid 32125896)
    • (2001) Cancer Causes and Control , vol.12 , Issue.1 , pp. 1-11
    • McMaster, M.L.1    Goldstein, A.M.2    Bromley, C.M.3    Ishibe, N.4    Parry, D.M.5
  • 3
    • 36849044547 scopus 로고    scopus 로고
    • Chordoma: The nonsarcoma primary bone tumor
    • DOI 10.1634/theoncologist.12-11-1344
    • Chugh R., Tawbi H., Lucas D. R., Biermann J. S., Schuetze S. M., Baker L. H., Chordoma: the nonsarcoma primary bone tumor. Oncologist 2007 12 11 1344 1350 2-s2.0-36849044547 10.1634/theoncologist.12-11-1344 (Pubitemid 350232608)
    • (2007) Oncologist , vol.12 , Issue.11 , pp. 1344-1350
    • Chugh, R.1    Tawbi, H.2    Lucas, D.R.3    Biermann, J.S.4    Schuetze, S.M.5    Baker, L.H.6
  • 4
    • 77954426772 scopus 로고    scopus 로고
    • Pediatric cervical chordoma: Report of two cases and a review of the current literature
    • Choi G. H., Yang -S M., Yoon D. H., Pediatric cervical chordoma: report of two cases and a review of the current literature. Child's Nervous System 2010 26 835 840
    • (2010) Child's Nervous System , vol.26 , pp. 835-840
    • Choi, G.H.1    Yang, M.-S.2    Yoon, D.H.3
  • 5
    • 67651163603 scopus 로고    scopus 로고
    • Cervical chordoma in childhood without typical vertebral bony destruction: Case report and review of the literature
    • 2-s2.0-67651163603 10.1097/BRS.0b013e3181a8ced8
    • Zhou H., Liu Z., Liu C., Ma Q., Liu X., Jiang L., Wei F., Cervical chordoma in childhood without typical vertebral bony destruction: case report and review of the literature. Spine 2009 34 14 E493 E497 2-s2.0-67651163603 10.1097/BRS.0b013e3181a8ced8
    • (2009) Spine , vol.34 , Issue.14
    • Zhou, H.1    Liu, Z.2    Liu, C.3    Ma, Q.4    Liu, X.5    Jiang, L.6    Wei, F.7
  • 6
    • 84863138255 scopus 로고    scopus 로고
    • Analysis of prognostic factors for patients with chordoma with use of the California Cancer Registry
    • Lee J., Bhatia N. N., Hoang B. H., Ziogas A., Zell J. A., Analysis of prognostic factors for patients with chordoma with use of the California Cancer Registry. The Journal of Bone & Joint Surgery 2012 94 356 363
    • (2012) The Journal of Bone & Joint Surgery , vol.94 , pp. 356-363
    • Lee, J.1    Bhatia, N.N.2    Hoang, B.H.3    Ziogas, A.4    Zell, J.A.5
  • 8
    • 79955482649 scopus 로고    scopus 로고
    • Extra-axial soft tissue chordoma of wrist
    • 2-s2.0-79955482649 10.1016/j.prp.2011.02.001
    • Suzuki H., Yamashiro K., Takeda H., Nojima T., Usui M., Extra-axial soft tissue chordoma of wrist. Pathology Research and Practice 2011 207 5 327 331 2-s2.0-79955482649 10.1016/j.prp.2011.02.001
    • (2011) Pathology Research and Practice , vol.207 , Issue.5 , pp. 327-331
    • Suzuki, H.1    Yamashiro, K.2    Takeda, H.3    Nojima, T.4    Usui, M.5
  • 10
    • 0027693687 scopus 로고
    • Extra-axial chordoma. Report of a case with immunohistochemical study
    • 2-s2.0-0027693687
    • Cesinaro A. M., Maiorana A., Collina G., Fano R. A., Extra-axial chordoma. Report of a case with immunohistochemical study. Pathologica 1993 85 1100 755 760 2-s2.0-0027693687
    • (1993) Pathologica , vol.85 , Issue.1100 , pp. 755-760
    • Cesinaro, A.M.1    Maiorana, A.2    Collina, G.3    Fano, R.A.4
  • 11
    • 2442647461 scopus 로고    scopus 로고
    • Chordoma mimicking the trigeminal schwannoma: A case report
    • DOI 10.1016/S0899-7071(03)00236-5, PII S0899707103002365
    • Lu C. Y., Chai C. Y., Chiang I. C., Chordoma mimicking the trigeminal schwannoma: a case report. Clinical Imaging 2004 28 3 187 190 2-s2.0-2442647461 10.1016/S0899-7071(03)00236-5 (Pubitemid 38670246)
    • (2004) Clinical Imaging , vol.28 , Issue.3 , pp. 187-190
    • Lu, C.-Y.1    Chai, C.-Y.2    Chiang, I.-C.3
  • 12
    • 33751558611 scopus 로고    scopus 로고
    • Diagnosing an extra-axial chordoma of the proximal tibia with the help of brachyury, a molecule required for notochordal differentiation
    • DOI 10.1007/s00256-006-0167-4
    • O'Donnell P., Tirabosco R., Vujovic S., Bartlett W., Briggs T. W. R., Henderson S., Boshoff C., Flanagan A. M., Diagnosing an extra-axial chordoma of the proximal tibia with the help of Brachyury, a molecule required for notochordal differentiation. Skeletal Radiology 2007 36 1 59 65 2-s2.0-33751558611 10.1007/s00256-006-0167-4 (Pubitemid 44843170)
    • (2007) Skeletal Radiology , vol.36 , Issue.1 , pp. 59-65
    • O'Donnell, P.1    Tirabosco, R.2    Vujovic, S.3    Bartlett, W.4    Briggs, T.W.R.5    Henderson, S.6    Boshoff, C.7    Flanagan, A.M.8
  • 14
    • 0008050121 scopus 로고
    • The fine structure of chordoma with particular reference to the physaliphorous cell
    • 2-s2.0-0008050121
    • Friedmann I., Harrison D. F., Bird E. S., The fine structure of chordoma with particular reference to the physaliphorous cell. Journal of Clinical Pathology 1962 15 116 125 2-s2.0-0008050121
    • (1962) Journal of Clinical Pathology , vol.15 , pp. 116-125
    • Friedmann, I.1    Harrison, D.F.2    Bird, E.S.3
  • 15
    • 0026074108 scopus 로고
    • Fine-needle aspiration biopsy in the preoperative diagnosis of chordoma: A study of 17 cases with application of electron microscopic, histochemical, and immunocytochemical examination
    • 2-s2.0-0026074108 10.1016/0046-8177(91)90056-U
    • Walaas L., Kindblom L. G., Fine-needle aspiration biopsy in the preoperative diagnosis of chordoma: a study of 17 cases with application of electron microscopic, histochemical, and immunocytochemical examination. Human Pathology 1991 22 1 22 28 2-s2.0-0026074108 10.1016/0046-8177(91)90056-U
    • (1991) Human Pathology , vol.22 , Issue.1 , pp. 22-28
    • Walaas, L.1    Kindblom, L.G.2
  • 16
    • 0000327822 scopus 로고
    • Ueber das Vorkommen von Resten der Chorda dorsalis bei Menschen nach der Geburt und über ihr Verhältniss zu den Gallertgeschwülsten am Clivus
    • Müller H., Ueber das Vorkommen von Resten der Chorda dorsalis bei Menschen nach der Geburt und über ihr Verhältniss zu den Gallertgeschwülsten am Clivus. Zeitung Für Rationelle Medizin 1858 2 202
    • (1858) Zeitung für Rationelle Medizin , vol.2 , pp. 202
    • Müller, H.1
  • 18
    • 0021992159 scopus 로고
    • Ecchordosis physaliphora and chordoma: A comparative ultrastructural study
    • Ho K. L., Ecchordosis physaliphora and chordoma: a comparative ultrastructural study. Clinical Neuropathology 1985 4 2 77 86 2-s2.0-0021992159 (Pubitemid 15117449)
    • (1985) Clinical Neuropathology , vol.4 , Issue.2 , pp. 77-86
    • Ho, K.L.1
  • 19
    • 56649117465 scopus 로고    scopus 로고
    • Cerebrospinal fluid rhinorrhea secondary to ecchordosis physaliphora
    • 2-s2.0-56649117465 10.1055/s-0028-1087221
    • Alli A., Clark M., Mansell N. J., Cerebrospinal fluid rhinorrhea secondary to ecchordosis physaliphora. Skull Base 2008 18 6 395 400 2-s2.0-56649117465 10.1055/s-0028-1087221
    • (2008) Skull Base , vol.18 , Issue.6 , pp. 395-400
    • Alli, A.1    Clark, M.2    Mansell, N.J.3
  • 21
    • 85014845330 scopus 로고    scopus 로고
    • Primary clear cell chondrosarcoma of the spine: A case report of a rare entity and a review of the literature
    • 693137 10.1155/2012/693137
    • Paidakakos N. A., Rovlias A., Rokas E., Theodoropoulos S., Katafygiotis P., Primary clear cell chondrosarcoma of the spine: a case report of a rare entity and a review of the literature. Case Reports in Oncological Medicine 2012 2012 4 693137 10.1155/2012/693137
    • (2012) Case Reports in Oncological Medicine , vol.2012 , pp. 4
    • Paidakakos, N.A.1    Rovlias, A.2    Rokas, E.3    Theodoropoulos, S.4    Katafygiotis, P.5
  • 22
    • 0028957881 scopus 로고
    • Chondroid chordoma: A hyalinized chordoma without cartilaginous differentiation
    • 2-s2.0-0028957881
    • Jeffrey P. B., Biava C. G., Davis R. L., Chondroid chordoma: a hyalinized chordoma without cartilaginous differentiation. American Journal of Clinical Pathology 1995 103 3 271 279 2-s2.0-0028957881
    • (1995) American Journal of Clinical Pathology , vol.103 , Issue.3 , pp. 271-279
    • Jeffrey, P.B.1    Biava, C.G.2    Davis, R.L.3
  • 24
    • 77949693187 scopus 로고    scopus 로고
    • Clinical and histopathologic features of chordomas in children and young adults
    • 2-s2.0-77949693187 10.2350/09-01-0584.1
    • Ridenour R. V., Ahrens W. A., Folpe A. L., Miller D. V., Clinical and histopathologic features of chordomas in children and young adults. Pediatric and Developmental Pathology 2010 13 1 9 17 2-s2.0-77949693187 10.2350/09-01-0584.1
    • (2010) Pediatric and Developmental Pathology , vol.13 , Issue.1 , pp. 9-17
    • Ridenour, R.V.1    Ahrens, W.A.2    Folpe, A.L.3    Miller, D.V.4
  • 25
    • 0018113113 scopus 로고
    • High amputation of the sacrum for extirpation of tumors. Principles and technique
    • 2-s2.0-0018113113
    • Stener B., Gunterberg B., High amputation of the sacrum for extirpation of tumors. Principles and technique. Spine 1978 3 4 351 366 2-s2.0-0018113113
    • (1978) Spine , vol.3 , Issue.4 , pp. 351-366
    • Stener, B.1    Gunterberg, B.2
  • 26
    • 0021271729 scopus 로고
    • Clinicopathologic study of sacrococcygeal chordoma
    • Kaiser T. E., Pritchard D. J., Unni K. K., Clinicopathologic study of sacrococcygeal chordoma. Cancer 1984 53 11 2574 2578 2-s2.0-0021271729 (Pubitemid 14102506)
    • (1984) Cancer , vol.53 , Issue.11 , pp. 2574-2578
    • Kaiser, T.E.1    Pritchard, D.J.2    Unni, K.K.3
  • 28
    • 33748307482 scopus 로고    scopus 로고
    • Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chordomas
    • DOI 10.1227/01.NEU.0000223441.51012.9D, PII 0000612320060800000003
    • Tzortzidis F., Elahi F., Wright D., Natarajan S. K., Sekhar L. N., Patient outcome at long-term follow-up after aggressive microsurgical resection of cranial base chordomas. Neurosurgery 2006 59 2 230 236 2-s2.0-33748307482 10.1227/01.NEU.0000223441.51012.9D (Pubitemid 44325841)
    • (2006) Neurosurgery , vol.59 , Issue.2 , pp. 230-236
    • Tzortzidis, F.1    Elahi, F.2    Wright, D.3    Natarajan, S.K.4    Sekhar, L.N.5
  • 29
    • 0032254622 scopus 로고    scopus 로고
    • CT and MRI appearances of a thoracic chordoma
    • Murphy J. M., Wallis F., Toland J., Toner M., Wilson G. F., CT and MRI appearances of a thoracic chordoma. European Radiology 1998 8 9 1677 1679 2-s2.0-0032254622 (Pubitemid 128662718)
    • (1998) European Radiology , vol.8 , Issue.9 , pp. 1677-1679
    • Murphy, J.M.1    Wallis, F.2    Toland, J.3    Toner, M.4    Wilson, G.F.5
  • 31
    • 0032716554 scopus 로고    scopus 로고
    • Proton therapy for tumors of the skull base
    • Munzenrider J. E., Liebsch N. J., Proton therapy for tumors of the skull base. Strahlentherapie und Onkologie 1999 175 2 57 63 2-s2.0-0032716554 (Pubitemid 29533454)
    • (1999) Strahlentherapie und Onkologie , vol.175 , Issue.SUPPL. 2 , pp. 57-63
    • Munzenrider, J.E.1    Liebsch, N.J.2
  • 32
    • 0021807145 scopus 로고
    • Precision, high dose radiotherapy. II. Helium ion treatment of tumors adjacent to critical central nervous system structures
    • Saunders W. M., Chen G. T. Y., Austin-Seymour M., Precision, high dose radiotherapy. II. Helium ion treatment of tumors adjacent to critical central nervous system structures. International Journal of Radiation Oncology Biology Physics 1985 11 7 1339 1347 2-s2.0-0021807145 (Pubitemid 15067918)
    • (1985) International Journal of Radiation Oncology Biology Physics , vol.11 , Issue.7 , pp. 1339-1347
    • Saunders, W.M.1    Chen, G.T.Y.2    Austin-Seymour, M.3
  • 34
    • 0032905513 scopus 로고    scopus 로고
    • Sacral chordoma: 40-Year experience at a major cancer center
    • DOI 10.1097/00006123-199901000-00041
    • York J. E., Kaczaraj A., Abi-Said D., Fuller G. N., Skibber J. M., Janjan N. A., Gokaslan Z. L., Sacral chordoma: 40-Year experience at a major cancer center. Neurosurgery 1999 44 1 74 80 2-s2.0-0032905513 10.1097/00006123- 199901000-00041 (Pubitemid 29016169)
    • (1999) Neurosurgery , vol.44 , Issue.1 , pp. 74-80
    • York, J.E.1    Kaczaraj, A.2    Abi-Said, D.3    Fuller, G.N.4    Skibber, J.M.5    Janjan, N.A.6    Gokaslan, Z.L.7
  • 39
    • 34447260736 scopus 로고    scopus 로고
    • Sunitinib, a multitargeted tyrosine kinase inhibitor, in the management of gastrointestinal stromal tumor
    • DOI 10.1007/s11912-007-0040-1
    • George S., Sunitinib, a multitargeted tyrosine kinase inhibitor, in the management of gastrointestinal stromal tumor. Current Oncology Reports 2007 9 4 323 327 2-s2.0-34447260736 10.1007/s11912-007-0040-1 (Pubitemid 47045167)
    • (2007) Current Oncology Reports , vol.9 , Issue.4 , pp. 323-327
    • George, S.1
  • 42
    • 33845787013 scopus 로고    scopus 로고
    • Effectiveness of cetuximab/gefitinib in the therapy of a sacral chordoma
    • DOI 10.1159/000096283
    • Hof H., Welzel T., Debus J., Effectiveness of cetuximab/gefitinib in the therapy of a sacral chordoma. Onkologie 2006 29 12 572 574 2-s2.0-33845787013 10.1159/000096283 (Pubitemid 46005781)
    • (2006) Onkologie , vol.29 , Issue.12 , pp. 572-574
    • Hof, H.1    Welzel, T.2    Debus, J.3
  • 43
    • 73349107416 scopus 로고    scopus 로고
    • Response to erlotinib in a patient with treatment refractory chordoma
    • 2-s2.0-73349107416 10.1097/CAD.0b013e328330c7f0
    • Singhal N., Kotasek D., Parnis F. X., Response to erlotinib in a patient with treatment refractory chordoma. Anti-Cancer Drugs 2009 20 10 953 955 2-s2.0-73349107416 10.1097/CAD.0b013e328330c7f0
    • (2009) Anti-Cancer Drugs , vol.20 , Issue.10 , pp. 953-955
    • Singhal, N.1    Kotasek, D.2    Parnis, F.X.3
  • 44
  • 45
    • 0034792246 scopus 로고    scopus 로고
    • Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CHI
    • DOI 10.1002/gcc.1184
    • Scheil S., Brüderlein S., Liehr T., Starke H., Herms J., Schulte M., Möller P., Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CHI. Genes Chromosomes and Cancer 2001 32 3 203 211 2-s2.0-0034792246 10.1002/gcc.1184 (Pubitemid 32953974)
    • (2001) Genes Chromosomes and Cancer , vol.32 , Issue.3 , pp. 203-211
    • Scheil, S.1    Bruderlein, S.2    Liehr, T.3    Starke, H.4    Herms, J.5    Schulte, M.6    Moller, P.7
  • 46
    • 80052655562 scopus 로고    scopus 로고
    • In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs
    • 10.1186/1748-717X-6-116, ARTICLE 116
    • Kato T. A., Tsuda A., Uesaka M., Fujimori A., Tsujii H., Okayasu R., In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs. Radiation Oncology 2011 6 1, article 116 10.1186/1748-717X-6-116
    • (2011) Radiation Oncology , vol.6 , Issue.1
    • Kato, T.A.1    Tsuda, A.2    Uesaka, M.3    Fujimori, A.4    Tsujii, H.5    Okayasu, R.6
  • 47
    • 84865505198 scopus 로고    scopus 로고
    • Establishment and characterization of a novel chordoma cell line: CH22
    • Liu X., Nielsen G. P., Rosenberg A. E., Establishment and characterization of a novel chordoma cell line: CH22. Journal of Orthopaedic Research 2012 30 1666 1673
    • (2012) Journal of Orthopaedic Research , vol.30 , pp. 1666-1673
    • Liu, X.1    Nielsen, G.P.2    Rosenberg, A.E.3
  • 48
    • 77952469589 scopus 로고    scopus 로고
    • Derivation and characterization of an extra-axial chordoma cell line (EACH-1) from a scapular tumor
    • 2-s2.0-77952469589 10.2106/JBJS.I.00594
    • DeComas A. M., Penfornis P., Harris M. R., Meyer M. S., Pochampally R. R., Derivation and characterization of an extra-axial chordoma cell line (EACH-1) from a scapular tumor. Journal of Bone and Joint Surgery A 2010 92 5 1231 1240 2-s2.0-77952469589 10.2106/JBJS.I.00594
    • (2010) Journal of Bone and Joint Surgery A , vol.92 , Issue.5 , pp. 1231-1240
    • Decomas, A.M.1    Penfornis, P.2    Harris, M.R.3    Meyer, M.S.4    Pochampally, R.R.5
  • 50
    • 80053410072 scopus 로고    scopus 로고
    • Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target: Laboratory investigation
    • 10.3171/2011.5.JNS11185
    • Hsu W., Mohyeldin A., Shah S. R., Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target: laboratory investigation. Journal of Neurosurgery 2011 115 4 760 769 10.3171/2011.5. JNS11185
    • (2011) Journal of Neurosurgery , vol.115 , Issue.4 , pp. 760-769
    • Hsu, W.1    Mohyeldin, A.2    Shah, S.R.3
  • 52
  • 54
    • 33746027560 scopus 로고    scopus 로고
    • Sox9 is required for notochord maintenance in mice
    • DOI 10.1016/j.ydbio.2006.03.014, PII S001216060600203X
    • Barrionuevo F., Taketo M. M., Scherer G., Kispert A., Sox9 is required for notochord maintenance in mice. Developmental Biology 2006 295 1 128 140 2-s2.0-33746027560 10.1016/j.ydbio.2006.03.014 (Pubitemid 44063495)
    • (2006) Developmental Biology , vol.295 , Issue.1 , pp. 128-140
    • Barrionuevo, F.1    Taketo, M.M.2    Scherer, G.3    Kispert, A.4
  • 55
    • 56649094382 scopus 로고    scopus 로고
    • Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: A tissue microarray-based comparative analysis
    • 2-s2.0-56649094382 10.1038/modpathol.2008.144
    • Oakley G. J., Fuhrer K., Seethala R. R., Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis. Modern Pathology 2008 21 12 1461 1469 2-s2.0-56649094382 10.1038/modpathol.2008.144
    • (2008) Modern Pathology , vol.21 , Issue.12 , pp. 1461-1469
    • Oakley, G.J.1    Fuhrer, K.2    Seethala, R.R.3
  • 56
    • 33744503681 scopus 로고    scopus 로고
    • Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas
    • DOI 10.1002/path.1969
    • Vujovic S., Henderson S., Presneau N., Odell E., Jacques T. S., Tirabosco R., Boshoff C., Flanagan A. M., Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas. Journal of Pathology 2006 209 2 157 165 2-s2.0-33744503681 10.1002/path.1969 (Pubitemid 43805410)
    • (2006) Journal of Pathology , vol.209 , Issue.2 , pp. 157-165
    • Vujovic, S.1    Henderson, S.2    Presneau, N.3    Odell, E.4    Jacques, T.S.5    Tirabosco, R.6    Boshoff, C.7    Flanagan, A.M.8
  • 57
    • 76649138588 scopus 로고    scopus 로고
    • The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
    • 2-s2.0-76649138588 10.1172/JCI38379
    • Fernando R. I., Litzinger M., Trono P., Hamilton D. H., Schlom J., Palena C., The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. Journal of Clinical Investigation 2010 120 2 533 544 2-s2.0-76649138588 10.1172/JCI38379
    • (2010) Journal of Clinical Investigation , vol.120 , Issue.2 , pp. 533-544
    • Fernando, R.I.1    Litzinger, M.2    Trono, P.3    Hamilton, D.H.4    Schlom, J.5    Palena, C.6
  • 58
    • 84863955851 scopus 로고    scopus 로고
    • Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: An opportunity for novel interventions against lung cancer
    • Roselli M., Fernando R. I., Guadagni F., Spila A., Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer. Clinical Cancer Research 2012 18 3868 3879
    • (2012) Clinical Cancer Research , vol.18 , pp. 3868-3879
    • Roselli, M.1    Fernando, R.I.2    Guadagni, F.3    Spila, A.4
  • 60
    • 20444391006 scopus 로고    scopus 로고
    • Chromosome 7 abnormalities are common in chordomas
    • DOI 10.1016/j.cancergencyto.2004.11.016, PII S0165460804005874
    • Brandal P., Bjerkehagen B., Danielsen H., Heim S., Chromosome 7 abnormalities are common in chordomas. Cancer Genetics and Cytogenetics 2005 160 1 15 21 2-s2.0-20444391006 10.1016/j.cancergencyto.2004.11.016 (Pubitemid 40798131)
    • (2005) Cancer Genetics and Cytogenetics , vol.160 , Issue.1 , pp. 15-21
    • Brandal, P.1    Bjerkehagen, B.2    Danielsen, H.3    Heim, S.4
  • 61
    • 0033563457 scopus 로고    scopus 로고
    • The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancers
    • 2-s2.0-0033563457
    • Huang S., The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancers. Frontiers in Bioscience 1999 4 D528 532 2-s2.0-0033563457
    • (1999) Frontiers in Bioscience , vol.4
    • Huang, S.1
  • 63
    • 0034920306 scopus 로고    scopus 로고
    • Familial chordoma, a tumor of notochordal remnants, is linked to chromosome 7q33
    • DOI 10.1086/321982
    • Kelley M. J., Korczak J. F., Sheridan E., Yang X., Goldstein A. M., Parry D. M., Familial chordoma, a tumor of notochordal remnants, is linked to chromosome 7q33. American Journal of Human Genetics 2001 69 2 454 460 2-s2.0-0034920306 10.1086/321982 (Pubitemid 32695218)
    • (2001) American Journal of Human Genetics , vol.69 , Issue.2 , pp. 454-460
    • Kelley, M.J.1    Korczak, J.F.2    Sheridan, E.3    Yang, X.4    Goldstein, A.M.5    Parry, D.M.6
  • 64
    • 34648840795 scopus 로고    scopus 로고
    • New candidate chromosomal regions for chordoma development
    • DOI 10.1016/j.surneu.2006.11.046, PII S0090301906011463
    • Bayrakli F., Guney I., Kilic T., Ozek M., Pamir M. N., New candidate chromosomal regions for chordoma development. Surgical Neurology 2007 68 4 425 430 2-s2.0-34648840795 10.1016/j.surneu.2006.11.046 (Pubitemid 47464455)
    • (2007) Surgical Neurology , vol.68 , Issue.4 , pp. 425-430
    • Bayrakli, F.1    Guney, I.2    Kilic, T.3    Ozek, M.4    Pamir, M.N.5
  • 67
    • 22244463527 scopus 로고    scopus 로고
    • Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs)
    • DOI 10.1002/ijc.21006
    • Yang X., Beerman M., Bergen A. W., Parry D. M., Sheridan E., Liebsch N. J., Kelley M. J., Chanock S., Goldstein A. M., Corroboration of a familial chordoma locus on chromosome 7q and evidence of genetic heterogeneity using single nucleotide polymorphisms (SNPs). International Journal of Cancer 2005 116 3 487 491 2-s2.0-22244463527 10.1002/ijc.21006 (Pubitemid 40993348)
    • (2005) International Journal of Cancer , vol.116 , Issue.3 , pp. 487-491
    • Yang, X.1    Beerman, M.2    Bergen, A.W.3    Parry, D.M.4    Sheridan, E.5    Liebsch, N.J.6    Kelley, M.J.7    Chanock, S.8    Goldstein, A.M.9
  • 68
    • 70350654372 scopus 로고    scopus 로고
    • T (Brachyury) gene duplication confers major susceptibility to familial chordoma
    • Yang X. R., Ng D., Alcorta D. A., T (Brachyury) gene duplication confers major susceptibility to familial chordoma. Nature Genetics 2009 41 1176 1178
    • (2009) Nature Genetics , vol.41 , pp. 1176-1178
    • Yang, X.R.1    Ng, D.2    Alcorta, D.A.3
  • 69
    • 0029966604 scopus 로고    scopus 로고
    • The human homolog T of the mouse T (Brachyury) gene; Gene structure, cDNA sequence, and assignment to chromosome 6q27
    • 2-s2.0-0029966604
    • Edwards Y. H., Putt W., Lekoape K. M., Stott D., Fox M., Hopkinson D. A., Sowden J., The human homolog T of the mouse T (Brachyury) gene; gene structure, cDNA sequence, and assignment to chromosome 6q27. Genome Research 1996 6 3 226 233 2-s2.0-0029966604
    • (1996) Genome Research , vol.6 , Issue.3 , pp. 226-233
    • Edwards, Y.H.1    Putt, W.2    Lekoape, K.M.3    Stott, D.4    Fox, M.5    Hopkinson, D.A.6    Sowden, J.7
  • 71
    • 84868213270 scopus 로고    scopus 로고
    • A common single-nucleotide variant in T is strongly associated with chordoma
    • Pillay N., Plagnol V., Tarpey P. S., A common single-nucleotide variant in T is strongly associated with chordoma. Nature Genetics 2012 44 1185 1187
    • (2012) Nature Genetics , vol.44 , pp. 1185-1187
    • Pillay, N.1    Plagnol, V.2    Tarpey, P.S.3
  • 72
    • 0035370901 scopus 로고    scopus 로고
    • Notochord patterning of the endoderm
    • DOI 10.1006/dbio.2001.0214
    • Cleaver O., Krieg P. A., Notochord patterning of the endoderm. Developmental Biology 2001 234 1 1 12 2-s2.0-0035370901 10.1006/dbio.2001.0214 (Pubitemid 32477020)
    • (2001) Developmental Biology , vol.234 , Issue.1 , pp. 1-12
    • Cleaver, O.1    Krieg, P.A.2
  • 73
    • 33744459756 scopus 로고    scopus 로고
    • Brachyury and chordoma: The chondroid-chordoid dilemma resolved?
    • DOI 10.1002/path.1987
    • Romeo S., Hogendoorn P. C. W., Brachyury and chordoma: the chondroid-chordoid dilemma resolved? Journal of Pathology 2006 209 2 143 146 2-s2.0-33744459756 10.1002/path.1987 (Pubitemid 43805408)
    • (2006) Journal of Pathology , vol.209 , Issue.2 , pp. 143-146
    • Romeo, S.1    Hogendoorn, P.C.W.2
  • 74
    • 84855904849 scopus 로고    scopus 로고
    • Tracing notochord-derived cells using a Noto-cre mouse: Implications for intervertebral disc development
    • Mccann M. R., Tamplin O. J., Rossant J., Séguin C. A., Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development. Disease Models & Mechanisms 2012 5 73 82
    • (2012) Disease Models & Mechanisms , vol.5 , pp. 73-82
    • McCann, M.R.1    Tamplin, O.J.2    Rossant, J.3    Séguin, C.A.4
  • 75
    • 84982064361 scopus 로고
    • Development of the short-tailed mutant in the house mouse
    • Chesley P., Development of the short-tailed mutant in the house mouse. Journal of Experimental Zoology 1935 70 429 459
    • (1935) Journal of Experimental Zoology , vol.70 , pp. 429-459
    • Chesley, P.1
  • 76
    • 0000997169 scopus 로고
    • Genetical studies on the skeleton of the mouse. XXIII. The development of Brachyury and anury
    • Gruneberg H., Genetical studies on the skeleton of the mouse. XXIII. The development of Brachyury and anury. Journal of Embryology & Experimental Morphology 1958 6 424 443
    • (1958) Journal of Embryology & Experimental Morphology , vol.6 , pp. 424-443
    • Gruneberg, H.1
  • 78
    • 0025950213 scopus 로고
    • Wis mutant embryos
    • Herrmann B. G., Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development 1991 113 913 917 (Pubitemid 21900329)
    • (1991) Development , vol.113 , Issue.3 , pp. 913-917
    • Herrmann, B.G.1
  • 79
    • 35548971081 scopus 로고    scopus 로고
    • Tint maps to mouse chromosome 6 and may interact with a notochordal enhancer of Brachyury
    • DOI 10.1534/genetics.107.079715
    • Wu J. I., Centilli M. A., Vasquez G., Young S., Scolnick J., Durfee L. A., Spearow J. L., Schwantz S. D., Rennebeck G., Artzt K., tint maps to mouse chromosome 6 and may interact with a notochordal enhancer of Brachyury. Genetics 2007 177 2 1151 1161 2-s2.0-35548971081 10.1534/genetics.107.079715 (Pubitemid 350005662)
    • (2007) Genetics , vol.177 , Issue.2 , pp. 1151-1161
    • Wu, J.I.1    Centilli, M.A.2    Vasquez, G.3    Young, S.4    Scolnick, J.5    Durfee, L.A.6    Spearow, J.L.7    Schwantz, S.D.8    Rennebeck, G.9    Artzt, K.10
  • 80
    • 0025062325 scopus 로고
    • Cloning of the T gene required in mesoderm formation in the mouse
    • DOI 10.1038/343617a0
    • Herrmann B. G., Labeit S., Poustka A., King T. R., Lehrach H., Cloning of the T gene required in mesoderm formation in the mouse. Nature 1990 343 6259 617 622 2-s2.0-0025062325 10.1038/343617a0 (Pubitemid 20075500)
    • (1990) Nature , vol.343 , Issue.6259 , pp. 617-622
    • Herrmann, B.G.1    Labeit, S.2    Poustka, A.3    King, T.R.4    Lehrach, H.5
  • 81
    • 0025054992 scopus 로고
    • Expression pattern of the mouse T gene and its role in mesoderm formation
    • DOI 10.1038/343657a0
    • Wilkinson D. G., Bhatt S., Herrmann B. G., Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 1990 343 6259 657 659 2-s2.0-0025054992 10.1038/343657a0 (Pubitemid 20075515)
    • (1990) Nature , vol.343 , Issue.6259 , pp. 657-659
    • Wilkinson, D.G.1    Bhatt, S.2    Herrmann, B.G.3
  • 82
    • 0027282961 scopus 로고
    • The Brachyury gene encodes a novel DNA binding protein
    • Kispert A., Herrmann B. G., The Brachyury gene encodes a novel DNA binding protein. EMBO Journal 1993 12 8 3211 3220 2-s2.0-0027282961 (Pubitemid 23232752)
    • (1993) EMBO Journal , vol.12 , Issue.8 , pp. 3211-3220
    • Kispert, A.1    Herrmann, B.G.2
  • 83
    • 0025942785 scopus 로고
    • Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
    • Smith J. C., Price B. M. J., Green J. B. A., Weigel D., Herrmann B. G., Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 1991 67 1 79 87 2-s2.0-0025942785 (Pubitemid 121001426)
    • (1991) Cell , vol.67 , Issue.1 , pp. 79-87
    • Smith, J.C.1    Price, B.M.J.2    Green, J.B.A.3    Weigel, D.4    Herrmann, B.G.5
  • 84
    • 0027077930 scopus 로고
    • The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo
    • Schulte-Merker S., Ho R. K., Herrmann B. G., Nusslein-Volhard C., The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development 1992 116 4 1021 1032 2-s2.0-0027077930 (Pubitemid 23042442)
    • (1992) Development , vol.116 , Issue.4 , pp. 1021-1032
    • Schulte-Merker, S.1    Ho, R.K.2    Herrmann, B.G.3    Nusslein-Volhard, C.4
  • 85
    • 0028901934 scopus 로고
    • The chick Brachyury gene: Developmental expression pattern and response to axial induction by localized activin
    • 2-s2.0-0028901934 10.1006/dbio.1995.1090
    • Kispert A., Ortner H., Cooke J., Herrmann B. G., The chick Brachyury gene: developmental expression pattern and response to axial induction by localized activin. Developmental Biology 1995 168 2 406 415 2-s2.0-0028901934 10.1006/dbio.1995.1090
    • (1995) Developmental Biology , vol.168 , Issue.2 , pp. 406-415
    • Kispert, A.1    Ortner, H.2    Cooke, J.3    Herrmann, B.G.4
  • 86
    • 0028344796 scopus 로고
    • No tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene
    • Schulte-Merker S., Van Eeden F. J. M., Halpern M. E., Kimmel C. B., Nusslein-Volhard C., no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development 1994 120 4 1009 1015 2-s2.0-0028344796 (Pubitemid 24111563)
    • (1994) Development , vol.120 , Issue.4 , pp. 1009-1015
    • Schulte-Merker, S.1    Van Eeden, F.J.M.2    Halpern, M.E.3    Kimmel, C.B.4    Nusslein-Volhard, C.5
  • 87
    • 84871270841 scopus 로고    scopus 로고
    • Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging
    • e52020
    • Tang X., Jing L., Chen J., Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging. PLoS ONE 2012 7 e52020
    • (2012) PLoS ONE , vol.7
    • Tang, X.1    Jing, L.2    Chen, J.3
  • 88
    • 0027259166 scopus 로고
    • Function of vertebrate T gene
    • 2-s2.0-0027259166
    • Yasuo H., Satoh N., Function of vertebrate T gene. Nature 1993 364 6438 582 583 2-s2.0-0027259166
    • (1993) Nature , vol.364 , Issue.6438 , pp. 582-583
    • Yasuo, H.1    Satoh, N.2
  • 89
    • 0031055201 scopus 로고    scopus 로고
    • Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis
    • Corbo J. C., Levine M., Zeller R. W., Characterization of a notochord-specific enhancer from the Brachyury promoter region of the ascidian, Ciona intestinalis. Development 1997 124 3 589 602 2-s2.0-0031055201 (Pubitemid 27092425)
    • (1997) Development , vol.124 , Issue.3 , pp. 589-602
    • Corbo, J.C.1    Levine, M.2    Zeller, R.W.3
  • 90
    • 0029561722 scopus 로고
    • Conservation of Brachyury (T) genes in amphioxus and vertebrates: Developmental and evolutionary implications
    • Holland P. W. H., Koschorz B., Holland L. Z., Herrmann B. G., Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications. Development 1995 121 12 4283 4291 2-s2.0-0029561722 (Pubitemid 26007379)
    • (1995) Development , vol.121 , Issue.12 , pp. 4283-4291
    • Holland, P.W.H.1    Koschorz, B.2    Holland, L.Z.3    Herrmann, B.G.4
  • 91
    • 79952143437 scopus 로고    scopus 로고
    • Unexpected repertoire of metazoan transcription factors in the unicellular holozoan capsaspora owczarzaki
    • 2-s2.0-79952143437 10.1093/molbev/msq309
    • Sebé-Pedrós A., De Mendoza A., Lang B. F., Degnan B. M., Ruiz-Trillo I., Unexpected repertoire of metazoan transcription factors in the unicellular holozoan capsaspora owczarzaki. Molecular Biology and Evolution 2011 28 3 1241 1254 2-s2.0-79952143437 10.1093/molbev/msq309
    • (2011) Molecular Biology and Evolution , vol.28 , Issue.3 , pp. 1241-1254
    • Sebé-Pedrós, A.1    De Mendoza, A.2    Lang, B.F.3    Degnan, B.M.4    Ruiz-Trillo, I.5
  • 92
    • 0031914530 scopus 로고    scopus 로고
    • The T-box gene family
    • DOI 10.1002/(SICI)1521-1878(199801)20:1<9::AID-BIES4>3.0.CO;2-Q
    • Papaioannou V. E., Silver L. M., The T-box gene family. Bioessays 1998 20 9 19 (Pubitemid 28111327)
    • (1998) BioEssays , vol.20 , Issue.1 , pp. 9-19
    • Papaioannou, V.E.1    Silver, L.M.2
  • 93
    • 0242636547 scopus 로고    scopus 로고
    • Distinct expression patterns of the two T-box homologues Brachyury and Tbx2/3 in the placozoan Trichoplax adhaerens
    • DOI 10.1007/s00427-003-0353-5
    • Martinelli C., Spring J., Distinct expression patterns of the two T-box homologues Brachyury and Tbx2/3 in the placozoan Trichoplax adhaerens. Development Genes and Evolution 2003 213 10 492 499 2-s2.0-0242636547 10.1007/s00427-003-0353-5 (Pubitemid 37369231)
    • (2003) Development Genes and Evolution , vol.213 , Issue.10 , pp. 492-499
    • Martinelli, C.1    Spring, J.2
  • 94
    • 78651248336 scopus 로고    scopus 로고
    • Expansion, diversification, and expression of T-box family genes in Porifera
    • 2-s2.0-78651248336 10.1007/s00427-010-0344-2
    • Holstien K., Rivera A., Windsor P., Ding S., Leys S. P., Hill M., Hill A., Expansion, diversification, and expression of T-box family genes in Porifera. Development Genes and Evolution 2010 220 9-10 251 262 2-s2.0-78651248336 10.1007/s00427-010-0344-2
    • (2010) Development Genes and Evolution , vol.220 , Issue.9-10 , pp. 251-262
    • Holstien, K.1    Rivera, A.2    Windsor, P.3    Ding, S.4    Leys, S.P.5    Hill, M.6    Hill, A.7
  • 95
    • 24144468934 scopus 로고    scopus 로고
    • T-box and homeobox genes from the ctenophore Pleurobrachia pileus: Comparison of Brachyury, Tbx2/3 and Tlx in basal metazoans and bilaterians
    • DOI 10.1016/j.febslet.2005.08.008, PII S0014579305009804
    • Martinelli C., Spring J., T-box and homeobox genes from the ctenophore Pleurobrachia pileus: comparison of Brachyury, Tbx2/3 and Tlx in basal metazoans and bilaterians. FEBS Letters 2005 579 22 5024 5028 2-s2.0-24144468934 10.1016/j.febslet.2005.08.008 (Pubitemid 41242847)
    • (2005) FEBS Letters , vol.579 , Issue.22 , pp. 5024-5028
    • Martinelli, C.1    Spring, J.2
  • 97
    • 77649187456 scopus 로고    scopus 로고
    • Highly conserved functions of the Brachyury gene on morphogenetic movements: Insight from the early-diverging phylum Ctenophora
    • 2-s2.0-77649187456 10.1016/j.ydbio.2009.12.019
    • Yamada A., Martindale M. Q., Fukui A., Tochinai S., Highly conserved functions of the Brachyury gene on morphogenetic movements: insight from the early-diverging phylum Ctenophora. Developmental Biology 2010 339 1 212 222 2-s2.0-77649187456 10.1016/j.ydbio.2009.12.019
    • (2010) Developmental Biology , vol.339 , Issue.1 , pp. 212-222
    • Yamada, A.1    Martindale, M.Q.2    Fukui, A.3    Tochinai, S.4
  • 98
    • 0037274767 scopus 로고    scopus 로고
    • The ancestral role of Brachyury: Expression of NemBra1 in the basal cnidarian Nematostella vectensis (Anthozoa)
    • Scholz C. B., Technau U., The ancestral role of Brachyury: expression of NemBra1 in the basal cnidarian Nematostella vectensis (Anthozoa). Development Genes and Evolution 2003 212 12 563 570 2-s2.0-0037274767 (Pubitemid 36221585)
    • (2003) Development Genes and Evolution , vol.212 , Issue.12 , pp. 563-570
    • Scholz, C.B.1    Technau, U.2
  • 99
    • 0030481706 scopus 로고    scopus 로고
    • Drosophila brachyenteron regulates gene activity and morphogenesis in the gut
    • Singer J. B., Harbecke R., Kusch T., Reuter R., Lengyel J. A., Drosophila brachyenteron regulates gene activity and morphogenesis in the gut. Development 1996 122 12 3707 3718 2-s2.0-0030481706 (Pubitemid 27033867)
    • (1996) Development , vol.122 , Issue.12 , pp. 3707-3718
    • Singer, J.B.1    Harbecke, R.2    Kusch, T.3    Reuter, R.4    Lengyel, J.A.5
  • 100
    • 0028071623 scopus 로고
    • Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta
    • Kispert A., Herrmann B. G., Leptin M., Reuter R., Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes and Development 1994 8 18 2137 2150 2-s2.0-0028071623 (Pubitemid 24300090)
    • (1994) Genes and Development , vol.8 , Issue.18 , pp. 2137-2150
    • Kispert, A.1    Herrmann, B.G.2    Leptin, M.3    Reuter, R.4
  • 101
    • 0032841606 scopus 로고    scopus 로고
    • Functions for Drosophila brachyenteron and forkhead in mesoderm specification and cell signalling
    • Kusch T., Reuter R., Functions for Drosophila brachyenteron and forkhead in mesoderm specification and cell signalling. Development 1999 126 18 3991 4003 2-s2.0-0032841606 (Pubitemid 29481557)
    • (1999) Development , vol.126 , Issue.18 , pp. 3991-4003
    • Kusch, T.1    Reuter, R.2
  • 102
    • 70350149709 scopus 로고    scopus 로고
    • Direct activation of a notochord cis-regulatory module by Brachyury and FoxA in the ascidian Ciona intestinalis
    • 2-s2.0-70350149709 10.1242/dev.038141
    • Passamaneck Y. J., Katikala L., Perrone L., Dunn M. P., Oda-Ishii I., Di Gregorio A., Direct activation of a notochord cis-regulatory module by Brachyury and FoxA in the ascidian Ciona intestinalis. Development 2009 136 21 3679 3689 2-s2.0-70350149709 10.1242/dev.038141
    • (2009) Development , vol.136 , Issue.21 , pp. 3679-3689
    • Passamaneck, Y.J.1    Katikala, L.2    Perrone, L.3    Dunn, M.P.4    Oda-Ishii, I.5    Di Gregorio, A.6
  • 103
    • 0035504237 scopus 로고    scopus 로고
    • The role of Brachyury (T) during gastrulation movements in the sea urchin Lytechinus variegatus
    • DOI 10.1006/dbio.2001.0426
    • Gross J. M., McClay D. R., The role of Brachyury (T) during gastrulation movements in the sea urchin Lytechinus variegatus. Developmental Biology 2001 239 1 132 147 2-s2.0-0035504237 10.1006/dbio.2001.0426 (Pubitemid 33052058)
    • (2001) Developmental Biology , vol.239 , Issue.1 , pp. 132-147
    • Gross, J.M.1    McClay, D.R.2
  • 104
    • 0032123479 scopus 로고    scopus 로고
    • Novel pattern of Brachyury gene expression in hemichordate embryos
    • DOI 10.1016/S0925-4773(98)00078-1, PII S0925477398000781
    • Tagawa K., Humphreys T., Satoh N., Novel pattern of Brachyury gene expression in hemichordate embryos. Mechanisms of Development 1998 75 1-2 139 143 2-s2.0-0032123479 10.1016/S0925-4773(98)00078-1 (Pubitemid 28423693)
    • (1998) Mechanisms of Development , vol.75 , Issue.1-2 , pp. 139-143
    • Tagawa, K.1    Humphreys, T.2    Satoh, N.3
  • 105
    • 0034814669 scopus 로고    scopus 로고
    • Brachyury, the blastopore and the evolution of the mesoderm
    • DOI 10.1002/bies.1114
    • Technau U., Brachyury, the blastopore and the evolution of the mesoderm. BioEssays 2001 23 9 788 794 2-s2.0-0034814669 10.1002/bies.1114 (Pubitemid 32901330)
    • (2001) BioEssays , vol.23 , Issue.9 , pp. 788-794
    • Technau, U.1
  • 106
    • 0029165111 scopus 로고
    • The T protein encoded by Brachyury is a tissue-specific transcription factor
    • 2-s2.0-0029165111
    • Kispert A., Koschorz B., Herrmann B. G., The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO Journal 1995 14 19 4763 4772 2-s2.0-0029165111
    • (1995) EMBO Journal , vol.14 , Issue.19 , pp. 4763-4772
    • Kispert, A.1    Koschorz, B.2    Herrmann, B.G.3
  • 107
    • 0039706410 scopus 로고    scopus 로고
    • Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor
    • DOI 10.1038/39929
    • Müller C. W., Herrmann B. G., Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 1997 389 884 888 (Pubitemid 27462986)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 884-888
    • Muller, C.W.1    Herrmann, B.G.2
  • 108
    • 0035115845 scopus 로고    scopus 로고
    • T-targets: Clues to understanding the functions of T-box proteins
    • DOI 10.1046/j.1440-169X.2001.00556.x
    • Tada M., Smith J. C., T-targets: clues to understanding the functions of T-box proteins. Development Growth and Differentiation 2001 43 1 1 11 2-s2.0-0035115845 10.1046/j.1440-169X.2001.00556.x (Pubitemid 32165470)
    • (2001) Development Growth and Differentiation , vol.43 , Issue.1 , pp. 1-11
    • Tada, M.1    Smith, J.C.2
  • 109
    • 0031792721 scopus 로고    scopus 로고
    • The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element
    • Casey E. S., O'Reilly M. A. J., Conlon F. L., Smith J. C., The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element. Development 1998 125 19 3887 3894 2-s2.0-0031792721 (Pubitemid 28488363)
    • (1998) Development , vol.125 , Issue.19 , pp. 3887-3894
    • Casey, E.S.1    O'Reilly, M.-A.J.2    Conlon, F.L.3    Smith, J.C.4
  • 110
    • 0033379141 scopus 로고    scopus 로고
    • Regulation of Ci-tropomyosin-like, a Brachyury target gene in the ascidian, Ciona intestinalis
    • Di Gregorio A., Levine M., Regulation of Ci-tropomyosin-like, a Brachyury target gene in the ascidian, Ciona intestinalis. Development 1999 126 24 5599 5609 2-s2.0-0033379141 (Pubitemid 30035009)
    • (1999) Development , vol.126 , Issue.24 , pp. 5599-5609
    • Di Gregorio, A.1    Levine, M.2
  • 111
    • 63349087979 scopus 로고    scopus 로고
    • The evolutionarily conserved leprecan gene: Its regulation by Brachyury and its role in the developing Ciona notochord
    • 2-s2.0-63349087979 10.1016/j.ydbio.2009.02.007
    • Dunn M. P., Di Gregorio A., The evolutionarily conserved leprecan gene: its regulation by Brachyury and its role in the developing Ciona notochord. Developmental Biology 2009 328 2 561 574 2-s2.0-63349087979 10.1016/j.ydbio. 2009.02.007
    • (2009) Developmental Biology , vol.328 , Issue.2 , pp. 561-574
    • Dunn, M.P.1    Di Gregorio, A.2
  • 112
    • 0037083758 scopus 로고    scopus 로고
    • Brachyury proteins regulate target genes through modular binding sites in a cooperative fashion
    • DOI 10.1101/gad.213002
    • Kusch T., Storck T., Walldorf U., Reuter R., Brachyury proteins regulate target genes through modular binding sites in a cooperative fashion. Genes and Development 2002 16 4 518 529 2-s2.0-0037083758 10.1101/gad.213002 (Pubitemid 34165107)
    • (2002) Genes and Development , vol.16 , Issue.4 , pp. 518-529
    • Kusch, T.1    Storck, T.2    Walldorf, U.3    Reuter, R.4
  • 113
    • 0036608031 scopus 로고    scopus 로고
    • Brachyury target genes in the early sea urchin embryo isolated by differential macroarray screening
    • DOI 10.1006/dbio.2002.0654
    • Rast J. P., Cameron R. A., Poustka A. J., Davidson E. H., Brachyury target genes in the early sea urchin embryo isolated by differential macroarray screening. Developmental Biology 2002 246 1 191 208 2-s2.0-0036608031 10.1006/dbio.2002.0654 (Pubitemid 34625983)
    • (2002) Developmental Biology , vol.246 , Issue.1 , pp. 191-208
    • Rast, J.P.1    Cameron R.Andrew2    Poustka, A.J.3    Davidson, E.H.4
  • 114
    • 0034192048 scopus 로고    scopus 로고
    • A screen for targets of the Xenopus T-box gene Xbra
    • DOI 10.1016/S0925-4773(00)00260-4, PII S0925477300002604
    • Saka Y., Tada M., Smith J. C., A screen for targets of the Xenopus T-box gene Xbra. Mechanisms of Development 2000 93 1-2 27 39 2-s2.0-0034192048 10.1016/S0925-4773(00)00260-4 (Pubitemid 30216493)
    • (2000) Mechanisms of Development , vol.93 , Issue.1-2 , pp. 27-39
    • Saka, Y.1    Tada, M.2    Smith, J.C.3
  • 115
    • 0031736991 scopus 로고    scopus 로고
    • Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm
    • Tada M., Casey E. S., Fairclough L., Smith J. C., Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm. Development 1998 125 20 3997 4006 2-s2.0-0031736991 (Pubitemid 28515438)
    • (1998) Development , vol.125 , Issue.20 , pp. 3997-4006
    • Tada, M.1    Casey, E.S.2    Fairclough, L.3    Smith, J.C.4
  • 116
    • 0034130385 scopus 로고    scopus 로고
    • Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway
    • Tada M., Smith J. C., Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 2000 127 10 2227 2238 2-s2.0-0034130385 (Pubitemid 30386686)
    • (2000) Development , vol.127 , Issue.10 , pp. 2227-2238
    • Tada, M.1    Smith, J.C.2
  • 117
    • 0035072541 scopus 로고    scopus 로고
    • Making mesoderm - Upstream and downstream of Xbra
    • 2-s2.0-0035072541
    • Smith J. C., Making mesoderm-upstream and downstream of Xbra. International Journal of Developmental Biology 2001 45 1 219 224 2-s2.0-0035072541
    • (2001) International Journal of Developmental Biology , vol.45 , Issue.1 , pp. 219-224
    • Smith, J.C.1
  • 119
    • 34447575733 scopus 로고    scopus 로고
    • Lineage-independent mosaic expression and regulation of the Ciona multidom gene in the ancestral notochord
    • DOI 10.1002/dvdy.21213
    • Oda-Ishii I., Di Gregorio A., Lineage-independent mosaic expression and regulation of the Ciona multidom gene in the ancestral notochord. Developmental Dynamics 2007 236 7 1806 1819 2-s2.0-34447575733 10.1002/dvdy.21213 (Pubitemid 47076013)
    • (2007) Developmental Dynamics , vol.236 , Issue.7 , pp. 1806-1819
    • Oda-Ishii, I.1    Di Gregorio, A.2
  • 120
    • 0034254484 scopus 로고    scopus 로고
    • Characterization of Brachyury-downstream notochord genes in the Ciona intestinalis embryo
    • DOI 10.1006/dbio.2000.9765
    • Hotta K., Takahashi H., Asakura T., Saitoh B., Takatori N., Satou Y., Satoh N., Characterization of Brachyury -downstream notochord genes in the Ciona intestinalis embryo. Developmental Biology 2000 224 1 69 80 2-s2.0-0034254484 10.1006/dbio.2000.9765 (Pubitemid 30602821)
    • (2000) Developmental Biology , vol.224 , Issue.1 , pp. 69-80
    • Hotta, K.1    Takahashi, H.2    Asakura, T.3    Saitoh, B.4    Takatori, N.5    Satou, Y.6    Satoh, N.7
  • 121
    • 37749042201 scopus 로고    scopus 로고
    • Brachyury -downstream gene sets in a chordate, Ciona intestinalis: Integrating notochord specification, morphogenesis and chordate evolution
    • 2-s2.0-37749042201 10.1111/j.1525-142X.2007.00212.x
    • Hotta K., Takahashi H., Satoh N., Gojobori T., Brachyury -downstream gene sets in a chordate, Ciona intestinalis: integrating notochord specification, morphogenesis and chordate evolution. Evolution and Development 2008 10 1 37 51 2-s2.0-37749042201 10.1111/j.1525-142X.2007.00212.x
    • (2008) Evolution and Development , vol.10 , Issue.1 , pp. 37-51
    • Hotta, K.1    Takahashi, H.2    Satoh, N.3    Gojobori, T.4
  • 122
    • 63349112380 scopus 로고    scopus 로고
    • Evolutionary conservation of vertebrate notochord genes in the ascidian Ciona intestinalis
    • 2-s2.0-63349112380 10.1002/dvg.20403
    • Kugler J. E., Passamaneck Y. J., Feldman T. J., Beh J., Regnier T. W., Di Gregorio A., Evolutionary conservation of vertebrate notochord genes in the ascidian Ciona intestinalis. Genesis 2008 46 11 697 710 2-s2.0-63349112380 10.1002/dvg.20403
    • (2008) Genesis , vol.46 , Issue.11 , pp. 697-710
    • Kugler, J.E.1    Passamaneck, Y.J.2    Feldman, T.J.3    Beh, J.4    Regnier, T.W.5    Di Gregorio, A.6
  • 123
    • 77954948485 scopus 로고    scopus 로고
    • Temporal regulation of the muscle gene cascade by Macho1 and Tbx6 transcription factors in Ciona intestinalis
    • 2-s2.0-77954948485 10.1242/jcs.066910
    • Kugler J. E., Gazdoiu S., Oda-Ishii I., Passamaneck Y. J., Erives A. J., Di Gregorio A., Temporal regulation of the muscle gene cascade by Macho1 and Tbx6 transcription factors in Ciona intestinalis. Journal of Cell Science 2010 123 14 2453 2463 2-s2.0-77954948485 10.1242/jcs.066910
    • (2010) Journal of Cell Science , vol.123 , Issue.14 , pp. 2453-2463
    • Kugler, J.E.1    Gazdoiu, S.2    Oda-Ishii, I.3    Passamaneck, Y.J.4    Erives, A.J.5    Di Gregorio, A.6
  • 124
    • 77952173326 scopus 로고    scopus 로고
    • Genomic cis-regulatory networks in the early Ciona intestinalis embryo
    • 2-s2.0-77952173326 10.1242/dev.046789
    • Kubo A., Suzuki N., Yuan X., Nakai K., Satoh N., Imai K. S., Satou Y., Genomic cis-regulatory networks in the early Ciona intestinalis embryo. Development 2010 137 10 1613 1623 2-s2.0-77952173326 10.1242/dev.046789
    • (2010) Development , vol.137 , Issue.10 , pp. 1613-1623
    • Kubo, A.1    Suzuki, N.2    Yuan, X.3    Nakai, K.4    Satoh, N.5    Imai, K.S.6    Satou, Y.7
  • 125
    • 79958800756 scopus 로고    scopus 로고
    • The identification of transcription factors expressed in the notochord of Ciona intestinalis adds new potential players to the Brachyury gene regulatory network
    • 2-s2.0-79958800756 10.1002/dvdy.22656
    • José-Edwards D. S., Kerner P., Kugler J. E., Deng W., Jiang D., Di Gregorio A., The identification of transcription factors expressed in the notochord of Ciona intestinalis adds new potential players to the Brachyury gene regulatory network. Developmental Dynamics 2011 240 7 1793 1805 2-s2.0-79958800756 10.1002/dvdy.22656
    • (2011) Developmental Dynamics , vol.240 , Issue.7 , pp. 1793-1805
    • José-Edwards, D.S.1    Kerner, P.2    Kugler, J.E.3    Deng, W.4    Jiang, D.5    Di Gregorio, A.6
  • 126
    • 33748756124 scopus 로고    scopus 로고
    • TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc
    • DOI 10.1074/jbc.M601969200
    • Tsai T. T., Danielson K. G., Guttapalli A., Oguz E., Albert T. J., Shapiro I. M., Risbud M. V., TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc. Journal of Biological Chemistry 2006 281 35 25416 25424 2-s2.0-33748756124 10.1074/jbc.M601969200 (Pubitemid 44401930)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.35 , pp. 25416-25424
    • Tsai, T.-T.1    Danielson, K.G.2    Guttapalli, A.3    Oguz, E.4    Albert, T.J.5    Shapiro, I.M.6    Risbud, M.V.7
  • 129
    • 84859116916 scopus 로고    scopus 로고
    • Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells
    • e33346
    • Evans A. L., Faial T., Gilchrist M. J., Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells. PLoS ONE 2012 7 e33346
    • (2012) PLoS ONE , vol.7
    • Evans, A.L.1    Faial, T.2    Gilchrist, M.J.3
  • 130
    • 84861157570 scopus 로고    scopus 로고
    • Cancer vaccines targeting the epithelial-mesenchymal transition: Tissue distribution of Brachyury and other drivers of the mesenchymal-like phenotype of carcinomas
    • Hamilton D. H., Litzinger M. T., Fernando R. I., Huang B., Palena C., Cancer vaccines targeting the epithelial-mesenchymal transition: tissue distribution of Brachyury and other drivers of the mesenchymal-like phenotype of carcinomas. Seminars in Oncology 2012 39 358 366
    • (2012) Seminars in Oncology , vol.39 , pp. 358-366
    • Hamilton, D.H.1    Litzinger, M.T.2    Fernando, R.I.3    Huang, B.4    Palena, C.5
  • 132
    • 0027939990 scopus 로고
    • EFGF regulates Xbra expression during Xenopus gastrulation
    • Isaacs H. V., Pownall M. E., Slack J. M. W., eFGF regulates Xbra expression during Xenopus gastrulation. EMBO Journal 1994 13 19 4469 4481 2-s2.0-0027939990 (Pubitemid 24310197)
    • (1994) EMBO Journal , vol.13 , Issue.19 , pp. 4469-4481
    • Isaacs, H.V.1    Pownall, M.E.2    Slack, J.M.W.3
  • 133
    • 0344494808 scopus 로고    scopus 로고
    • Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development
    • DOI 10.1016/j.ydbio.2003.09.008
    • Griffin K. J. P., Kimelman D., Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development. Developmental Biology 2003 264 2 456 466 2-s2.0-0344494808 10.1016/j.ydbio.2003. 09.008 (Pubitemid 37490981)
    • (2003) Developmental Biology , vol.264 , Issue.2 , pp. 456-466
    • Griffin, K.J.P.1    Kimelman, D.2
  • 134
    • 34249893689 scopus 로고    scopus 로고
    • Direct activation by Ets and Zic is required for initial expression of the Brachyury gene in the ascidian notochord
    • DOI 10.1016/j.ydbio.2007.03.034, PII S0012160607002345
    • Matsumoto J., Kumano G., Nishida H., Direct activation by Ets and Zic is required for initial expression of the Brachyury gene in the ascidian notochord. Developmental Biology 2007 306 2 870 882 2-s2.0-34249893689 10.1016/j.ydbio.2007.03.034 (Pubitemid 46873532)
    • (2007) Developmental Biology , vol.306 , Issue.2 , pp. 870-882
    • Matsumoto, J.1    Kumano, G.2    Nishida, H.3
  • 135
    • 33846215631 scopus 로고    scopus 로고
    • FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos
    • DOI 10.1016/j.ydbio.2006.08.075, PII S0012160606011869
    • Yasuo H., Hudson C., FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos. Developmental Biology 2007 302 1 92 103 2-s2.0-33846215631 10.1016/j.ydbio.2006.08.075 (Pubitemid 46096927)
    • (2007) Developmental Biology , vol.302 , Issue.1 , pp. 92-103
    • Yasuo, H.1    Hudson, C.2
  • 136
    • 84867573028 scopus 로고    scopus 로고
    • An integrated functional genomics approach identifies the regulatory network directed by Brachyury (T) in chordoma
    • Nelson A. C., Pillay N., Henderson S., An integrated functional genomics approach identifies the regulatory network directed by Brachyury (T) in chordoma. Journal of Pathology 2012 228 274 285
    • (2012) Journal of Pathology , vol.228 , pp. 274-285
    • Nelson, A.C.1    Pillay, N.2    Henderson, S.3
  • 138
    • 80655123645 scopus 로고    scopus 로고
    • Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation
    • Ricke R. M., van Deursen J. M., Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation. Cell Cycle 2011 10 3645 3651
    • (2011) Cell Cycle , vol.10 , pp. 3645-3651
    • Ricke, R.M.1    Van Deursen, J.M.2
  • 139
    • 61549094059 scopus 로고    scopus 로고
    • The Notochord, Notochordal cell and CTGF/CCN-2: Ongoing activity from development through maturation
    • 2-s2.0-61549094059 10.1007/s12079-008-0031-5
    • Erwin W. M., The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation. Journal of Cell Communication and Signaling 2008 2 3-4 59 65 2-s2.0-61549094059 10.1007/s12079-008-0031-5
    • (2008) Journal of Cell Communication and Signaling , vol.2 , Issue.3-4 , pp. 59-65
    • Erwin, W.M.1
  • 140
    • 0029087408 scopus 로고
    • The emerging molecular genetics of sarcoma translocations
    • Ladanyi M., The emerging molecular genetics of sarcoma translocations. Diagnostic Molecular Pathology 1995 4 162 173
    • (1995) Diagnostic Molecular Pathology , vol.4 , pp. 162-173
    • Ladanyi, M.1
  • 141
    • 80054699756 scopus 로고    scopus 로고
    • Citron kinase controls abscission through RhoA and anillin
    • Gai M., Camera P., Dema A., Citron kinase controls abscission through RhoA and anillin. Molecular Biology of the Cell 2011 22 3768 3778
    • (2011) Molecular Biology of the Cell , vol.22 , pp. 3768-3778
    • Gai, M.1    Camera, P.2    Dema, A.3
  • 142
    • 41849138303 scopus 로고    scopus 로고
    • Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells
    • 2-s2.0-41849138303 10.1007/s12185-007-0013-z
    • Koldehoff M., Zakrzewski J. L., Klein-Hitpass L., Beelen D. W., Elmaagacli A. H., Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells. International Journal of Hematology 2008 87 1 39 47 2-s2.0-41849138303 10.1007/s12185-007-0013-z
    • (2008) International Journal of Hematology , vol.87 , Issue.1 , pp. 39-47
    • Koldehoff, M.1    Zakrzewski, J.L.2    Klein-Hitpass, L.3    Beelen, D.W.4    Elmaagacli, A.H.5
  • 143
    • 84866514143 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients
    • Dasgupta S., Pal P., Mukhopadhyay N. D., A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients. International Journal of Oncology 2012 41 1405 1410
    • (2012) International Journal of Oncology , vol.41 , pp. 1405-1410
    • Dasgupta, S.1    Pal, P.2    Mukhopadhyay, N.D.3
  • 144
    • 78649640148 scopus 로고    scopus 로고
    • TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling
    • 2-s2.0-78649640148 10.1158/1541-7786.MCR-10-0334
    • Paulino V. M., Yang Z., Kloss J., Ennis M. J., Armstrong B. A., Loftus J. C., Tran N. L., TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. Molecular Cancer Research 2010 8 11 1558 1567 2-s2.0-78649640148 10.1158/1541-7786.MCR-10-0334
    • (2010) Molecular Cancer Research , vol.8 , Issue.11 , pp. 1558-1567
    • Paulino, V.M.1    Yang, Z.2    Kloss, J.3    Ennis, M.J.4    Armstrong, B.A.5    Loftus, J.C.6    Tran, N.L.7
  • 145
    • 4544270602 scopus 로고    scopus 로고
    • Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates
    • DOI 10.1016/j.biochi.2004.07.010, PII S0300908404001178
    • Muto E., Tabata Y., Taneda T., Aoki Y., Muto A., Arai K. I., Watanabe S., Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates. Biochimie 2004 86 8 523 531 2-s2.0-4544270602 10.1016/j.biochi. 2004.07.010 (Pubitemid 39237650)
    • (2004) Biochimie , vol.86 , Issue.8 , pp. 523-531
    • Muto, E.1    Tabata, Y.2    Taneda, T.3    Aoki, Y.4    Muto, A.5    Arai, K.-I.6    Watanabe, S.7
  • 147
    • 29844433852 scopus 로고    scopus 로고
    • A predominantly articular cartilage-associated gene, SCRG1, is induced by glucocorticoid and stimulates chondrogenesis in vitro
    • DOI 10.1016/j.joca.2005.07.015, PII S1063458405001998
    • Ochi K., Derfoul A., Tuan R. S., A predominantly articular cartilage-associated gene, SCRG1, is induced by glucocorticoid and stimulates chondrogenesis in vitro. Osteoarthritis and Cartilage 2006 14 1 30 38 2-s2.0-29844433852 10.1016/j.joca.2005.07.015 (Pubitemid 43034087)
    • (2006) Osteoarthritis and Cartilage , vol.14 , Issue.1 , pp. 30-38
    • Ochi, K.1    Derfoul, A.2    Tuan, R.S.3
  • 148
    • 36049030602 scopus 로고    scopus 로고
    • Transforming growth factor α suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis
    • DOI 10.1002/art.22968
    • Appleton C. T. G., Usmani S. E., Bernier S. M., Aigner T., Beier F., Transforming growth factor α suppression of articular chondrocyte phenotype and Sox9 expression in a rat model of osteoarthritis. Arthritis and Rheumatism 2007 56 11 3693 3705 2-s2.0-36049030602 10.1002/art.22968 (Pubitemid 350100704)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.11 , pp. 3693-3705
    • Appleton, C.T.G.1    Usmani, S.E.2    Bernier, S.M.3    Aigner, T.4    Beier, F.5
  • 149
    • 0030918366 scopus 로고    scopus 로고
    • The T transcription factor functions as a dimer and exhibits a common human polymorphism Gly-177-Asp in the conserved DNA-binding domain
    • DOI 10.1016/S0014-5793(97)00506-1, PII S0014579397005061
    • Papapetrou C., Edwards Y. H., Sowden J. C., The T transcription factor functions as a dimer and exhibits a common human polymorphism Gly-177-Asp in the conserved DNA-binding domain. FEBS Letters 1997 409 2 201 206 2-s2.0-0030918366 10.1016/S0014-5793(97)00506-1 (Pubitemid 27273876)
    • (1997) FEBS Letters , vol.409 , Issue.2 , pp. 201-206
    • Papapetrou, C.1    Edwards, Y.H.2    Sowden, J.C.3
  • 150
    • 0042062219 scopus 로고    scopus 로고
    • Evolution of Brachyury proteins: Identification of a novel regulatory domain conserved within Bilateria
    • DOI 10.1016/S0012-1606(03)00244-6
    • Marcellini S., Technau U., Smith J. C., Lemaire P., Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria. Developmental Biology 2003 260 2 352 361 2-s2.0-0042062219 10.1016/S0012-1606(03)00244-6 (Pubitemid 36960084)
    • (2003) Developmental Biology , vol.260 , Issue.2 , pp. 352-361
    • Marcellini, S.1    Technau, U.2    Smith, J.C.3    Lemaire, P.4
  • 151
    • 33645832195 scopus 로고    scopus 로고
    • When Brachyury meets Smad1: The evolution of bilateral symmetry during gastrulation
    • 2-s2.0-33645832195 10.1002/bies.20387
    • Marcellini S., When Brachyury meets Smad1: the evolution of bilateral symmetry during gastrulation. BioEssays 2006 28 4 413 420 2-s2.0-33645832195 10.1002/bies.20387
    • (2006) BioEssays , vol.28 , Issue.4 , pp. 413-420
    • Marcellini, S.1
  • 152
    • 82555187462 scopus 로고    scopus 로고
    • Brachyury and related tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity
    • e28394 10.1371/journal.pone.0028394
    • Pereira L. A., Wong M. S., Lim S. M., Brachyury and related tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity. PLoS ONE 2011 6 12 e28394 10.1371/journal.pone.0028394
    • (2011) PLoS ONE , vol.6 , Issue.12
    • Pereira, L.A.1    Wong, M.S.2    Lim, S.M.3
  • 153
    • 43249111060 scopus 로고    scopus 로고
    • Activator-to-repressor conversion of T-box transcription factors by the ripply family of Groucho/TLE-associated mediators
    • DOI 10.1128/MCB.01754-07
    • Kawamura A., Koshida S., Takada S., Activator-to-repressor conversion of T-box transcription factors by the ripply family of Groucho/TLE-associated mediators. Molecular and Cellular Biology 2008 28 10 3236 3244 2-s2.0-43249111060 10.1128/MCB.01754-07 (Pubitemid 351657088)
    • (2008) Molecular and Cellular Biology , vol.28 , Issue.10 , pp. 3236-3244
    • Kawamura, A.1    Koshida, S.2    Takada, S.3
  • 154
    • 0029061553 scopus 로고
    • Patterning of the mesoderm in Xenopus: Dose-dependent and synergistic effects of Brachyury and Pintallavis
    • 2-s2.0-0029061553
    • O'Reilly M. A. J., Smith J. C., Cunliffe V., Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis. Development 1995 121 5 1351 1359 2-s2.0-0029061553
    • (1995) Development , vol.121 , Issue.5 , pp. 1351-1359
    • O'Reilly, M.A.J.1    Smith, J.C.2    Cunliffe, V.3
  • 156
    • 17444397689 scopus 로고    scopus 로고
    • Ciona intestinalis: Chordate development made simple
    • DOI 10.1002/dvdy.20300
    • Passamaneck Y. J., Di Gregorio A., Ciona intestinalis: chordate development made simple. Developmental Dynamics 2005 233 1 1 19 2-s2.0-17444397689 10.1002/dvdy.20300 (Pubitemid 40548019)
    • (2005) Developmental Dynamics , vol.233 , Issue.1 , pp. 1-19
    • Passamaneck, Y.J.1    Di Gregorio, A.2
  • 157
    • 38349028678 scopus 로고    scopus 로고
    • Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction
    • 2-s2.0-38349028678 10.1242/dev.010173
    • Bielen H., Oberleitner S., Marcellini S., Gee L., Lemaire P., Bode H. R., Rupp R., Technau U., Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction. Development 2007 134 23 4187 4197 2-s2.0-38349028678 10.1242/dev.010173
    • (2007) Development , vol.134 , Issue.23 , pp. 4187-4197
    • Bielen, H.1    Oberleitner, S.2    Marcellini, S.3    Gee, L.4    Lemaire, P.5    Bode, H.R.6    Rupp, R.7    Technau, U.8
  • 158
    • 0030967671 scopus 로고    scopus 로고
    • Formation of the chordamesoderm in the amphioxus embryo: Analysis with Brachyury and fork head/HNF-3 genes
    • DOI 10.1007/s004270050086
    • Terazawa K., Satoh N., Formation of the chordamesoderm in the amphioxus embryo: analysis with Brachyury and fork head/HNF-3 genes. Development Genes and Evolution 1997 207 1 1 11 2-s2.0-0030967671 10.1007/s004270050086 (Pubitemid 27272003)
    • (1997) Development Genes and Evolution , vol.207 , Issue.1 , pp. 1-11
    • Terazawa, K.1    Satoh, N.2
  • 159
    • 46049114470 scopus 로고    scopus 로고
    • Regulation of Canonical Wnt Signaling by Brachyury Is Essential for Posterior Mesoderm Formation
    • DOI 10.1016/j.devcel.2008.04.013, PII S1534580708001767
    • Martin B. L., Kimelman D., Regulation of canonical wnt signaling by Brachyury is essential for posterior mesoderm formation. Developmental Cell 2008 15 1 121 133 2-s2.0-46049114470 10.1016/j.devcel.2008.04.013 (Pubitemid 351895595)
    • (2008) Developmental Cell , vol.15 , Issue.1 , pp. 121-133
    • Martin, B.L.1    Kimelman, D.2
  • 160
    • 0031771624 scopus 로고    scopus 로고
    • Mouse Brachyury the second (T2) is a gene next to classical T and a candidate gene for tct
    • Rennebeck G., Lader E., Fujimoto A., Lei E. P., Artzt K., Mouse Brachyury the second (T2) is a gene next to classical T and a candidate gene for tct. Genetics 1998 150 3 1125 1131 2-s2.0-0031771624 (Pubitemid 28510040)
    • (1998) Genetics , vol.150 , Issue.3 , pp. 1125-1131
    • Rennebeck, G.1    Lader, E.2    Fujimoto, A.3    Lei, E.P.4    Artzt, K.5
  • 161
    • 0027404718 scopus 로고
    • Rescue of the tail defect of Brachyury mice
    • Stott D., Kispert L. A., Herrmann B. G., Rescue of the tail defect of Brachyury mice. Genes and Development 1993 7 2 197 203 2-s2.0-0027404718 (Pubitemid 23084396)
    • (1993) Genes and Development , vol.7 , Issue.2 , pp. 197-203
    • Stott, D.1    Kispert, L.A.2    Herrmann, B.G.3
  • 162
    • 77950461913 scopus 로고    scopus 로고
    • No tail integrates two modes of mesoderm induction
    • 2-s2.0-77950461913 10.1242/dev.046318
    • Harvey S. A., Tümpel S., Dubrulle J., Schier A. F., Smith J. C., No tail integrates two modes of mesoderm induction. Development 2010 137 7 1127 1135 2-s2.0-77950461913 10.1242/dev.046318
    • (2010) Development , vol.137 , Issue.7 , pp. 1127-1135
    • Harvey, S.A.1    Tümpel, S.2    Dubrulle, J.3    Schier, A.F.4    Smith, J.C.5
  • 163
    • 0028848499 scopus 로고
    • BMP-4 regulates the dorsal-ventral differences in FGF/MAPKK-mediated mesoderm induction in Xenopus
    • 2-s2.0-0028848499 10.1006/dbio.1995.0019
    • Northrop J., Woods A., Seger R., Suzuki A., Ueno N., Krebs E., Kimelman D., BMP-4 regulates the dorsal-ventral differences in FGF/MAPKK-mediated mesoderm induction in Xenopus. Developmental Biology 1995 172 1 242 252 2-s2.0-0028848499 10.1006/dbio.1995.0019
    • (1995) Developmental Biology , vol.172 , Issue.1 , pp. 242-252
    • Northrop, J.1    Woods, A.2    Seger, R.3    Suzuki, A.4    Ueno, N.5    Krebs, E.6    Kimelman, D.7
  • 164
    • 0036387287 scopus 로고    scopus 로고
    • Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryo
    • 2-s2.0-0036387287 10.1006/dbio.2002.0786
    • Vonica A., Gumbiner B. M., Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryo. Developmental Biology 2002 250 1 112 127 2-s2.0-0036387287 10.1006/dbio.2002.0786
    • (2002) Developmental Biology , vol.250 , Issue.1 , pp. 112-127
    • Vonica, A.1    Gumbiner, B.M.2
  • 165
    • 39349091570 scopus 로고    scopus 로고
    • Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells
    • DOI 10.1182/blood-2007-02-074120
    • Zhang P., Li J., Tan Z., Wang C., Liu T., Chen L., Yong J., Jiang W., Sun X., Du L., Ding M., Deng H., Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood 2008 111 4 1933 1941 2-s2.0-39349091570 10.1182/blood-2007-02-074120 (Pubitemid 351451502)
    • (2008) Blood , vol.111 , Issue.4 , pp. 1933-1941
    • Zhang, P.1    Li, J.2    Tan, Z.3    Wang, C.4    Liu, T.5    Chen, L.6    Yong, J.7    Jiang, W.8    Sun, X.9    Du, L.10    Ding, M.11    Deng, H.12
  • 166
    • 0036638233 scopus 로고    scopus 로고
    • An essential role of a FoxD gene in notochord induction in Ciona embryos
    • 2-s2.0-0036638233
    • Imai K. S., Satoh N., Satou Y., An essential role of a FoxD gene in notochord induction in Ciona embryos. Development 2002 129 14 3441 3453 2-s2.0-0036638233
    • (2002) Development , vol.129 , Issue.14 , pp. 3441-3453
    • Imai, K.S.1    Satoh, N.2    Satou, Y.3
  • 167
    • 1842454958 scopus 로고    scopus 로고
    • A zinc finger transcription factor, ZicL, is a direct activator of Brachyury in the notochord specification of Ciona intestinalis
    • DOI 10.1242/dev.01011
    • Yagi K., Satou Y., Satoh N., A zinc finger transcription factor, ZicL, is a direct activator of Brachyury in the notochord specification of Ciona intestinalis. Development 2004 131 6 1279 1288 2-s2.0-1842454958 10.1242/dev.01011 (Pubitemid 38443882)
    • (2004) Development , vol.131 , Issue.6 , pp. 1279-1288
    • Yagi, K.1    Satou, Y.2    Satoh, N.3
  • 168
    • 33748167867 scopus 로고    scopus 로고
    • A signalling relay involving Nodal and Delta ligands acts during secondary notochord induction in Ciona embryos
    • DOI 10.1242/dev.02466
    • Hudson C., Yasuo H., A signalling relay involving Nodal and Delta ligands acts during secondary notochord induction in Ciona embryos. Development 2006 133 15 2855 2864 2-s2.0-33748167867 10.1242/dev.02466 (Pubitemid 44314263)
    • (2006) Development , vol.133 , Issue.15 , pp. 2855-2864
    • Hudson, C.1    Yasuo, H.2
  • 169
    • 33744458441 scopus 로고    scopus 로고
    • Regulatory blueprint for a chordate embryo
    • DOI 10.1126/science.1123404
    • Imai K. S., Levine M., Satoh N., Satou Y., Regulatory blueprint for a chordate embryo. Science 2006 312 5777 1183 1187 2-s2.0-33744458441 10.1126/science.1123404 (Pubitemid 43801138)
    • (2006) Science , vol.312 , Issue.5777 , pp. 1183-1187
    • Imai, K.S.1    Levine, M.2    Satoh, N.3    Satou, Y.4
  • 171
    • 0029831088 scopus 로고    scopus 로고
    • Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm
    • Conlon F. L., Sedgwick S. G., Weston K. M., Smith J. C., Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 1996 122 8 2427 2435 2-s2.0-0029831088 (Pubitemid 26265602)
    • (1996) Development , vol.122 , Issue.8 , pp. 2427-2435
    • Conlon, F.L.1    Sedgwick, S.G.2    Weston, K.M.3    Smith, J.C.4
  • 172
    • 0031572183 scopus 로고    scopus 로고
    • T promoter activity in the absence of functional T protein during axis formation and elongation in the mouse
    • DOI 10.1006/dbio.1997.8661
    • Schmidt C., Wilson V., Stott D., Beddington R. S. P., T promoter activity in the absence of functional T protein during axis formation and elongation in the mouse. Developmental Biology 1997 189 2 161 173 2-s2.0-0031572183 10.1006/dbio.1997.8661 (Pubitemid 27428360)
    • (1997) Developmental Biology , vol.189 , Issue.2 , pp. 161-173
    • Schmidt, C.1    Wilson, V.2    Stott, D.3    Beddington, R.S.P.4
  • 173
    • 0031903097 scopus 로고    scopus 로고
    • The snail repressor establishes a muscle/notochord boundary in the Ciona embryo
    • Fujiwara S., Corbo J. C., Levine M., The snail repressor establishes a muscle/notochord boundary in the Ciona embryo. Development 1998 125 13 2511 2520 2-s2.0-0031903097 (Pubitemid 28362411)
    • (1998) Development , vol.125 , Issue.13 , pp. 2511-2520
    • Fujiwara, S.1    Corbo, J.C.2    Levine, M.3
  • 175
    • 38348998668 scopus 로고    scopus 로고
    • Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus
    • 2-s2.0-38348998668 10.1242/dev.010645
    • Saka Y., Hagemann A. I., Piepenburg O., Smith J. C., Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus. Development 2007 134 23 4209 4218 2-s2.0-38348998668 10.1242/dev.010645
    • (2007) Development , vol.134 , Issue.23 , pp. 4209-4218
    • Saka, Y.1    Hagemann, A.I.2    Piepenburg, O.3    Smith, J.C.4
  • 177
    • 79960074830 scopus 로고    scopus 로고
    • Smek promotes histone deacetylation to suppress transcription of Wnt target gene Brachyury in pluripotent embryonic stem cells
    • 2-s2.0-79960074830 10.1038/cr.2011.47
    • Lyu J., Jho E. H., Lu W., Smek promotes histone deacetylation to suppress transcription of Wnt target gene Brachyury in pluripotent embryonic stem cells. Cell Research 2011 21 6 911 921 2-s2.0-79960074830 10.1038/cr.2011.47
    • (2011) Cell Research , vol.21 , Issue.6 , pp. 911-921
    • Lyu, J.1    Jho, E.H.2    Lu, W.3
  • 178
    • 84859302972 scopus 로고    scopus 로고
    • Characterization of cancer stem-like cells in chordoma
    • Aydemir E., Bayrak O. F., Sahin F., Characterization of cancer stem-like cells in chordoma. Journal of Neurosurgery 2012 116 810 820
    • (2012) Journal of Neurosurgery , vol.116 , pp. 810-820
    • Aydemir, E.1    Bayrak, O.F.2    Sahin, F.3
  • 179
    • 84865418683 scopus 로고    scopus 로고
    • The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells
    • article 377
    • Shimoda M., Sugiura T., Imajyo I., Ishii K., Chigita S., The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells. BMC Cancer 2012 12 article 377
    • (2012) BMC Cancer , vol.12
    • Shimoda, M.1    Sugiura, T.2    Imajyo, I.3    Ishii, K.4    Chigita, S.5
  • 180
    • 34247887629 scopus 로고    scopus 로고
    • The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell - Mediated cancer immunotherapy
    • DOI 10.1158/1078-0432.CCR-06-2353
    • Palena C., Polev D. E., Tsang K. Y., Fernando R. I., Litzinger M., Krukovskaya L. L., Baranova A. V., Kozlov A. P., Schlom J., The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy. Clinical Cancer Research 2007 13 8 2471 2478 2-s2.0-34247887629 10.1158/1078-0432.CCR-06-2353 (Pubitemid 46698599)
    • (2007) Clinical Cancer Research , vol.13 , Issue.8 , pp. 2471-2478
    • Palena, C.1    Polev, D.E.2    Tsang, K.Y.3    Fernando, R.I.4    Litzinger, M.5    Krukovskaya, L.L.6    Baranova, A.V.7    Kozlov, A.P.8    Schlom, J.9
  • 181
    • 80855144189 scopus 로고    scopus 로고
    • Increasing vaccine potency through exosome antigen targeting
    • Hartman Z. C., Wei J., Glass O. K., Increasing vaccine potency through exosome antigen targeting. Vaccine 2011 29 9361 9367
    • (2011) Vaccine , vol.29 , pp. 9361-9367
    • Hartman, Z.C.1    Wei, J.2    Glass, O.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.