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Volumn 7, Issue 12, 2012, Pages

Changes in the Molecular Phenotype of Nucleus Pulposus Cells with Intervertebral Disc Aging

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN ABUNDANT MEMBRANE ATTACHED SIGNAL PROTEIN 1; CD155 ANTIGEN; CD221 ANTIGEN; CD24 ANTIGEN; MOLECULAR MARKER; NEUROCHONDRIN; NEUROPILIN 1; THY 1 ANTIGEN; TRANSCRIPTION FACTOR BRACHYURY T; UNCLASSIFIED DRUG;

EID: 84871270841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052020     Document Type: Article
Times cited : (84)

References (75)
  • 1
    • 0023943445 scopus 로고
    • Human intervertebral disc: structure and function
    • Humzah MD, Soames RW, (1988) Human intervertebral disc: structure and function. Anat Rec 220: 337-356.
    • (1988) Anat Rec , vol.220 , pp. 337-356
    • Humzah, M.D.1    Soames, R.W.2
  • 2
    • 0029008944 scopus 로고
    • Aging and degeneration of the human intervertebral disc
    • Buckwalter JA, (1995) Aging and degeneration of the human intervertebral disc. Spine (Phila Pa 1976) 20: 1307-1314.
    • (1995) Spine (Phila Pa 1976) , vol.20 , pp. 1307-1314
    • Buckwalter, J.A.1
  • 3
    • 0036894572 scopus 로고    scopus 로고
    • Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science
    • Boos N, Weissbach S, Rohrbach H, Weiler C, Spratt KF, et al. (2002) Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine (Phila Pa 1976) 27: 2631-2644.
    • (2002) Spine (Phila Pa 1976) , vol.27 , pp. 2631-2644
    • Boos, N.1    Weissbach, S.2    Rohrbach, H.3    Weiler, C.4    Spratt, K.F.5
  • 4
    • 3042819382 scopus 로고    scopus 로고
    • Low back pain: pathophysiology and management
    • Biyani A, Andersson GB, (2004) Low back pain: pathophysiology and management. J Am Acad Orthop Surg 12: 106-115.
    • (2004) J Am Acad Orthop Surg , vol.12 , pp. 106-115
    • Biyani, A.1    Andersson, G.B.2
  • 5
    • 33645556769 scopus 로고    scopus 로고
    • Lumbar disc disorders and low-back pain: socioeconomic factors and consequences
    • Katz JN, (2006) Lumbar disc disorders and low-back pain: socioeconomic factors and consequences. J Bone Joint Surg Am 88Suppl 2: 21-24.
    • (2006) J Bone Joint Surg Am , vol.88 , pp. 21-24
    • Katz, J.N.1
  • 6
    • 41649119847 scopus 로고    scopus 로고
    • Current developments in tissue engineering of nucleus pulposus for the treatment of intervertebral disc degeneration
    • Sebastine IM, Williams DJ, (2007) Current developments in tissue engineering of nucleus pulposus for the treatment of intervertebral disc degeneration. Conf Proc IEEE Eng Med Biol Soc 2007: 6401-6406.
    • (2007) Conf Proc IEEE Eng Med Biol Soc , vol.2007 , pp. 6401-6406
    • Sebastine, I.M.1    Williams, D.J.2
  • 7
    • 80052009188 scopus 로고    scopus 로고
    • Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine
    • Bowles RD, Gebhard HH, Hartl R, Bonassar LJ, (2011) Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine. Proc Natl Acad Sci U S A 108: 13106-13111.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13106-13111
    • Bowles, R.D.1    Gebhard, H.H.2    Hartl, R.3    Bonassar, L.J.4
  • 8
    • 0021147075 scopus 로고
    • Morphologic changes in annulus fibrosus during aging. An ultrastructural study in rats
    • Postacchini F, Bellocci M, Massobrio M, (1984) Morphologic changes in annulus fibrosus during aging. An ultrastructural study in rats. Spine (Phila Pa 1976) 9: 596-603.
    • (1984) Spine (Phila Pa 1976) , vol.9 , pp. 596-603
    • Postacchini, F.1    Bellocci, M.2    Massobrio, M.3
  • 9
    • 0029014260 scopus 로고
    • The development of fibrocartilage in the rat intervertebral disc
    • Rufai A, Benjamin M, Ralphs JR, (1995) The development of fibrocartilage in the rat intervertebral disc. Anat Embryol (Berl) 192: 53-62.
    • (1995) Anat Embryol (Berl) , vol.192 , pp. 53-62
    • Rufai, A.1    Benjamin, M.2    Ralphs, J.R.3
  • 10
    • 57149118250 scopus 로고    scopus 로고
    • Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation
    • Choi KS, Cohn MJ, Harfe BD, (2008) Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn 237: 3953-3958.
    • (2008) Dev Dyn , vol.237 , pp. 3953-3958
    • Choi, K.S.1    Cohn, M.J.2    Harfe, B.D.3
  • 11
    • 0020461748 scopus 로고
    • Ultrastructure of the human intervertebral disc: II. Cells of the nucleus pulposus
    • Trout JJ, Buckwalter JA, Moore KC, (1982) Ultrastructure of the human intervertebral disc: II. Cells of the nucleus pulposus. Anat Rec 204: 307-314.
    • (1982) Anat Rec , vol.204 , pp. 307-314
    • Trout, J.J.1    Buckwalter, J.A.2    Moore, K.C.3
  • 12
    • 33748564012 scopus 로고    scopus 로고
    • Molecular phenotypes of notochordal cells purified from immature nucleus pulposus
    • Chen J, Yan W, Setton LA, (2006) Molecular phenotypes of notochordal cells purified from immature nucleus pulposus. Eur Spine J 15Suppl 15: 303-311.
    • (2006) Eur Spine J , vol.15 , pp. 303-311
    • Chen, J.1    Yan, W.2    Setton, L.A.3
  • 13
    • 0033406327 scopus 로고    scopus 로고
    • Viscoelastic properties of intervertebral disc cells. Identification of two biomechanically distinct cell populations
    • Guilak F, Ting-Beall HP, Baer AE, Trickey WR, Erickson GR, et al. (1999) Viscoelastic properties of intervertebral disc cells. Identification of two biomechanically distinct cell populations. Spine 24: 2475-2483.
    • (1999) Spine , vol.24 , pp. 2475-2483
    • Guilak, F.1    Ting-Beall, H.P.2    Baer, A.E.3    Trickey, W.R.4    Erickson, G.R.5
  • 14
    • 10344267546 scopus 로고    scopus 로고
    • Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison
    • Hunter CJ, Matyas JR, Duncan NA, (2004) Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison. Journal of Anatomy 205: 357-362.
    • (2004) Journal of Anatomy , vol.205 , pp. 357-362
    • Hunter, C.J.1    Matyas, J.R.2    Duncan, N.A.3
  • 15
    • 0002714538 scopus 로고
    • The development of the human intervertebral disc
    • In: Ghosh P, editor, Boca Raton, FL: CRC Press
    • Taylor JR, Twomey LT (1988) The development of the human intervertebral disc. In: Ghosh P, editor. The Biology of the Intervertebral Disc. Boca Raton, FL: CRC Press. 39-82.
    • (1988) The Biology of the Intervertebral Disc , pp. 39-82
    • Taylor, J.R.1    Twomey, L.T.2
  • 16
    • 18744399818 scopus 로고    scopus 로고
    • Elastic fibre organization in the intervertebral discs of the bovine tail
    • Yu J, Winlove PC, Roberts S, Urban JP, (2002) Elastic fibre organization in the intervertebral discs of the bovine tail. Journal of Anatomy 201: 465-475.
    • (2002) Journal of Anatomy , vol.201 , pp. 465-475
    • Yu, J.1    Winlove, P.C.2    Roberts, S.3    Urban, J.P.4
  • 17
    • 0026326160 scopus 로고
    • 1991 Volvo Award in basic sciences. Collagen types around the cells of the intervertebral disc and cartilage end plate: an immunolocalization study
    • Roberts S, Menage J, Duance V, Wotton S, Ayad S, (1991) 1991 Volvo Award in basic sciences. Collagen types around the cells of the intervertebral disc and cartilage end plate: an immunolocalization study. Spine 16: 1030-1038.
    • (1991) Spine , vol.16 , pp. 1030-1038
    • Roberts, S.1    Menage, J.2    Duance, V.3    Wotton, S.4    Ayad, S.5
  • 18
    • 0002321529 scopus 로고
    • Biochemistry of the intervertebral disc
    • In: Jayson MIV, editor, New York: Churchill Livingstone
    • Bayliss MT, Johnstone B (1992) Biochemistry of the intervertebral disc. In: Jayson MIV, editor. The Lumbar Spine and Back Pain. New York: Churchill Livingstone. 111-131.
    • (1992) The Lumbar Spine and Back Pain , pp. 111-131
    • Bayliss, M.T.1    Johnstone, B.2
  • 19
    • 0027220026 scopus 로고
    • Biochemistry of the intervertebral disc
    • Oegema TRJ, (1993) Biochemistry of the intervertebral disc. Clinics in Sports Medicine 12: 419-439.
    • (1993) Clinics in Sports Medicine , vol.12 , pp. 419-439
    • Oegema, T.R.J.1
  • 20
    • 0035040548 scopus 로고    scopus 로고
    • Extracellular matrix in development of the intervertebral disc
    • Hayes AJ, Benjamin M, Ralphs JR, (2001) Extracellular matrix in development of the intervertebral disc. Matrix Biol 20: 107-121.
    • (2001) Matrix Biol , vol.20 , pp. 107-121
    • Hayes, A.J.1    Benjamin, M.2    Ralphs, J.R.3
  • 21
    • 0029813162 scopus 로고    scopus 로고
    • The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration
    • Antoniou J, Steffen T, Nelson F, Winterbottom N, Hollander AP, et al. (1996) The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Clin Invest 98: 996-1003.
    • (1996) J Clin Invest , vol.98 , pp. 996-1003
    • Antoniou, J.1    Steffen, T.2    Nelson, F.3    Winterbottom, N.4    Hollander, A.P.5
  • 22
    • 0031573622 scopus 로고    scopus 로고
    • 1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs
    • Nerlich AG, Schleicher ED, Boos N, (1997) 1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs. Spine (Phila Pa 1976) 22: 2781-2795.
    • (1997) Spine (Phila Pa 1976) , vol.22 , pp. 2781-2795
    • Nerlich, A.G.1    Schleicher, E.D.2    Boos, N.3
  • 23
    • 0020326310 scopus 로고
    • Ultrastructure of the human intervertebral disc: I. Changes in notochordal cells with age
    • Trout JJ, Buckwalter JA, Moore KC, Landas SK, (1982) Ultrastructure of the human intervertebral disc: I. Changes in notochordal cells with age. Tissue and Cell 14: 359-369.
    • (1982) Tissue and Cell , vol.14 , pp. 359-369
    • Trout, J.J.1    Buckwalter, J.A.2    Moore, K.C.3    Landas, S.K.4
  • 24
    • 0033540274 scopus 로고    scopus 로고
    • Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis
    • Aguiar DJ, Johnson SL, Oegema TR, (1999) Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis. Exp Cell Res 246: 129-137.
    • (1999) Exp Cell Res , vol.246 , pp. 129-137
    • Aguiar, D.J.1    Johnson, S.L.2    Oegema, T.R.3
  • 25
    • 3042517948 scopus 로고    scopus 로고
    • Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc
    • Boyd LM, Chen J, Kraus VB, Setton LA, (2004) Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. Spine (Phila Pa 1976) 29: 2217-2222.
    • (2004) Spine (Phila Pa 1976) , vol.29 , pp. 2217-2222
    • Boyd, L.M.1    Chen, J.2    Kraus, V.B.3    Setton, L.A.4
  • 26
    • 0037648850 scopus 로고    scopus 로고
    • The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs
    • Kim KW, Lim TH, Kim JG, Jeong ST, Masuda K, et al. (2003) The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs. Spine 28: 982-990.
    • (2003) Spine , vol.28 , pp. 982-990
    • Kim, K.W.1    Lim, T.H.2    Kim, J.G.3    Jeong, S.T.4    Masuda, K.5
  • 27
    • 70350772321 scopus 로고    scopus 로고
    • Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc
    • Chen J, Jing L, Gilchrist CL, Richardson WJ, Fitch RD, et al. (2009) Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. Connect Tissue Res 50: 294-306.
    • (2009) Connect Tissue Res , vol.50 , pp. 294-306
    • Chen, J.1    Jing, L.2    Gilchrist, C.L.3    Richardson, W.J.4    Fitch, R.D.5
  • 29
    • 80455174499 scopus 로고    scopus 로고
    • Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions
    • Gilchrist CL, Darling EM, Chen J, Setton LA, (2011) Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions. PLoS One 6: e27170.
    • (2011) PLoS One , vol.6
    • Gilchrist, C.L.1    Darling, E.M.2    Chen, J.3    Setton, L.A.4
  • 30
    • 27844438525 scopus 로고    scopus 로고
    • CD24 is expressed specifically in the nucleus pulposus of intervertebral discs
    • Fujita N, Miyamoto T, Imai J, Hosogane N, Suzuki T, et al. (2005) CD24 is expressed specifically in the nucleus pulposus of intervertebral discs. Biochem Biophys Res Commun 338: 1890-1896.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1890-1896
    • Fujita, N.1    Miyamoto, T.2    Imai, J.3    Hosogane, N.4    Suzuki, T.5
  • 31
    • 37249032718 scopus 로고    scopus 로고
    • A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat
    • Lee CR, Sakai D, Nakai T, Toyama K, Mochida J, et al. (2007) A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat. Eur Spine J 16: 2174-2185.
    • (2007) Eur Spine J , vol.16 , pp. 2174-2185
    • Lee, C.R.1    Sakai, D.2    Nakai, T.3    Toyama, K.4    Mochida, J.5
  • 32
    • 67651151247 scopus 로고    scopus 로고
    • Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus
    • Sakai D, Nakai T, Mochida J, Alini M, Grad S, (2009) Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus. Spine (Phila Pa 1976) 34: 1448-1456.
    • (2009) Spine (Phila Pa 1976) , vol.34 , pp. 1448-1456
    • Sakai, D.1    Nakai, T.2    Mochida, J.3    Alini, M.4    Grad, S.5
  • 33
    • 77949474632 scopus 로고    scopus 로고
    • Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
    • Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA, (2010) Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes. Arthritis Res Ther 12: R22.
    • (2010) Arthritis Res Ther , vol.12
    • Minogue, B.M.1    Richardson, S.M.2    Zeef, L.A.3    Freemont, A.J.4    Hoyland, J.A.5
  • 34
    • 77949455250 scopus 로고    scopus 로고
    • Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers
    • Gilson A, Dreger M, Urban JP, (2010) Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers. Arthritis Res Ther 12: R24.
    • (2010) Arthritis Res Ther , vol.12
    • Gilson, A.1    Dreger, M.2    Urban, J.P.3
  • 35
    • 76549130659 scopus 로고    scopus 로고
    • Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration
    • Rutges J, Creemers LB, Dhert W, Milz S, Sakai D, et al. (2010) Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration. Osteoarthritis Cartilage 18: 416-423.
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 416-423
    • Rutges, J.1    Creemers, L.B.2    Dhert, W.3    Milz, S.4    Sakai, D.5
  • 36
    • 0033767175 scopus 로고    scopus 로고
    • CD44 expression in the developing and growing rat intervertebral disc
    • Stevens JW, Kurriger GL, Carter AS, Maynard JA, (2000) CD44 expression in the developing and growing rat intervertebral disc. Dev Dyn 219: 381-390.
    • (2000) Dev Dyn , vol.219 , pp. 381-390
    • Stevens, J.W.1    Kurriger, G.L.2    Carter, A.S.3    Maynard, J.A.4
  • 37
    • 78649582384 scopus 로고    scopus 로고
    • Interleukin-17 synergizes with IFNgamma or TNFalpha to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells
    • Gabr MA, Jing L, Helbling AR, Sinclair SM, Allen KD, et al. (2011) Interleukin-17 synergizes with IFNgamma or TNFalpha to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells. J Orthop Res 29: 1-7.
    • (2011) J Orthop Res , vol.29 , pp. 1-7
    • Gabr, M.A.1    Jing, L.2    Helbling, A.R.3    Sinclair, S.M.4    Allen, K.D.5
  • 38
    • 84867883651 scopus 로고    scopus 로고
    • Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc
    • Jing L, So S, Lim SW, Richardson WJ, Fitch RD, et al. (2012) Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc. J Orthop Res 30: 1923-1931.
    • (2012) J Orthop Res , vol.30 , pp. 1923-1931
    • Jing, L.1    So, S.2    Lim, S.W.3    Richardson, W.J.4    Fitch, R.D.5
  • 39
    • 0032055960 scopus 로고    scopus 로고
    • Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls
    • Gruber HE, Hanley EN Jr, (1998) Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls. Spine (Phila Pa 1976) 23: 751-757.
    • (1998) Spine (Phila Pa 1976) , vol.23 , pp. 751-757
    • Gruber, H.E.1    Hanley Jr., E.N.2
  • 40
    • 34548620230 scopus 로고    scopus 로고
    • The cell biology of intervertebral disc aging and degeneration
    • Zhao CQ, Wang LM, Jiang LS, Dai LY, (2007) The cell biology of intervertebral disc aging and degeneration. Ageing Res Rev 6: 247-261.
    • (2007) Ageing Res Rev , vol.6 , pp. 247-261
    • Zhao, C.Q.1    Wang, L.M.2    Jiang, L.S.3    Dai, L.Y.4
  • 41
    • 0023218531 scopus 로고
    • Degeneration and the chemical composition of the human lumbar intervertebral disc
    • Pearce RH, Grimmer BJ, Adams ME, (1987) Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res 5: 198-205.
    • (1987) J Orthop Res , vol.5 , pp. 198-205
    • Pearce, R.H.1    Grimmer, B.J.2    Adams, M.E.3
  • 42
    • 0032928369 scopus 로고    scopus 로고
    • Immunohistochemical localization of a novel acidic calmodulin-binding protein, NAP-22, in the rat brain
    • Iino S, Kobayashi S, Maekawa S, (1999) Immunohistochemical localization of a novel acidic calmodulin-binding protein, NAP-22, in the rat brain. Neuroscience 91: 1435-1444.
    • (1999) Neuroscience , vol.91 , pp. 1435-1444
    • Iino, S.1    Kobayashi, S.2    Maekawa, S.3
  • 44
    • 79952830159 scopus 로고    scopus 로고
    • WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line
    • Goodfellow SJ, Rebello MR, Toska E, Zeef LA, Rudd SG, et al. (2011) WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line. Biochem J 435: 113-125.
    • (2011) Biochem J , vol.435 , pp. 113-125
    • Goodfellow, S.J.1    Rebello, M.R.2    Toska, E.3    Zeef, L.A.4    Rudd, S.G.5
  • 45
    • 65249109840 scopus 로고    scopus 로고
    • Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1)
    • Hartl M, Nist A, Khan MI, Valovka T, Bister K, (2009) Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1). Proc Natl Acad Sci U S A 106: 5604-5609.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5604-5609
    • Hartl, M.1    Nist, A.2    Khan, M.I.3    Valovka, T.4    Bister, K.5
  • 46
    • 2542446346 scopus 로고    scopus 로고
    • Expression of neurochondrin in the developing and adult mouse brain
    • Istvanffy R, Vogt Weisenhorn DM, Floss T, Wurst W, (2004) Expression of neurochondrin in the developing and adult mouse brain. Dev Genes Evol 214: 206-209.
    • (2004) Dev Genes Evol , vol.214 , pp. 206-209
    • Istvanffy, R.1    Vogt Weisenhorn, D.M.2    Floss, T.3    Wurst, W.4
  • 48
    • 1642472772 scopus 로고    scopus 로고
    • Identification of the mouse neurochondrin promoter region and the responsible region for cell type specific gene regulation
    • Dateki M, Mochizuki R, Yanai K, Fukamizu A, (2004) Identification of the mouse neurochondrin promoter region and the responsible region for cell type specific gene regulation. Neurosci Lett 356: 107-110.
    • (2004) Neurosci Lett , vol.356 , pp. 107-110
    • Dateki, M.1    Mochizuki, R.2    Yanai, K.3    Fukamizu, A.4
  • 49
    • 0034871173 scopus 로고    scopus 로고
    • The role of the notochord in vertebral column formation
    • Fleming A, Keynes RJ, Tannahill D, (2001) The role of the notochord in vertebral column formation. Journal of Anatomy 199: 177-180.
    • (2001) Journal of Anatomy , vol.199 , pp. 177-180
    • Fleming, A.1    Keynes, R.J.2    Tannahill, D.3
  • 50
  • 51
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M, (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 52
    • 0036009760 scopus 로고    scopus 로고
    • VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
    • Soker S, Miao HQ, Nomi M, Takashima S, Klagsbrun M, (2002) VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J Cell Biochem 85: 357-368.
    • (2002) J Cell Biochem , vol.85 , pp. 357-368
    • Soker, S.1    Miao, H.Q.2    Nomi, M.3    Takashima, S.4    Klagsbrun, M.5
  • 53
    • 0030847193 scopus 로고    scopus 로고
    • Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
    • He Z, Tessier-Lavigne M, (1997) Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90: 739-751.
    • (1997) Cell , vol.90 , pp. 739-751
    • He, Z.1    Tessier-Lavigne, M.2
  • 54
    • 77955476299 scopus 로고    scopus 로고
    • Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc
    • Tolofari SK, Richardson SM, Freemont AJ, Hoyland JA, (2010) Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc. Arthritis Res Ther 12: R1.
    • (2010) Arthritis Res Ther , vol.12
    • Tolofari, S.K.1    Richardson, S.M.2    Freemont, A.J.3    Hoyland, J.A.4
  • 55
    • 0027282961 scopus 로고
    • The Brachyury gene encodes a novel DNA binding protein
    • Kispert A, Hermann BG, (1993) The Brachyury gene encodes a novel DNA binding protein. EMBO J 12: 4898-4899.
    • (1993) EMBO J , vol.12 , pp. 4898-4899
    • Kispert, A.1    Hermann, B.G.2
  • 56
    • 0028031460 scopus 로고
    • The T genes in embryogenesis
    • Herrmann BG, Kispert A, (1994) The T genes in embryogenesis. Trends Genet 10: 280-286.
    • (1994) Trends Genet , vol.10 , pp. 280-286
    • Herrmann, B.G.1    Kispert, A.2
  • 57
    • 33744503681 scopus 로고    scopus 로고
    • Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas
    • Vujovic S, Henderson S, Presneau N, Odell E, Jacques TS, et al. (2006) Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas. J Pathol 209: 157-165.
    • (2006) J Pathol , vol.209 , pp. 157-165
    • Vujovic, S.1    Henderson, S.2    Presneau, N.3    Odell, E.4    Jacques, T.S.5
  • 58
    • 0020326310 scopus 로고
    • Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age
    • Trout JJ, Buckwalter JA, Moore KC, Landas SK, (1982) Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age. Tissue Cell 14: 359-369.
    • (1982) Tissue Cell , vol.14 , pp. 359-369
    • Trout, J.J.1    Buckwalter, J.A.2    Moore, K.C.3    Landas, S.K.4
  • 59
    • 13544263786 scopus 로고    scopus 로고
    • Tumour biological aspects of CD24, a mucin-like adhesion molecule
    • Kristiansen G, Sammar M, Altevogt P, (2004) Tumour biological aspects of CD24, a mucin-like adhesion molecule. J Mol Histol 35: 255-262.
    • (2004) J Mol Histol , vol.35 , pp. 255-262
    • Kristiansen, G.1    Sammar, M.2    Altevogt, P.3
  • 60
    • 0030981928 scopus 로고    scopus 로고
    • Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice
    • Nielsen PJ, Lorenz B, Muller AM, Wenger RH, Brombacher F, et al. (1997) Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood 89: 1058-1067.
    • (1997) Blood , vol.89 , pp. 1058-1067
    • Nielsen, P.J.1    Lorenz, B.2    Muller, A.M.3    Wenger, R.H.4    Brombacher, F.5
  • 61
    • 33745984808 scopus 로고    scopus 로고
    • Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis
    • Rege TA, Hagood JS, (2006) Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J 20: 1045-1054.
    • (2006) FASEB J , vol.20 , pp. 1045-1054
    • Rege, T.A.1    Hagood, J.S.2
  • 63
  • 64
    • 0024519677 scopus 로고
    • Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily
    • Mendelsohn CL, Wimmer E, Racaniello VR, (1989) Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell 56: 855-865.
    • (1989) Cell , vol.56 , pp. 855-865
    • Mendelsohn, C.L.1    Wimmer, E.2    Racaniello, V.R.3
  • 65
    • 75949093670 scopus 로고    scopus 로고
    • A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions
    • Xu Z, Jin B, (2010) A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions. Cell Mol Immunol 7: 11-19.
    • (2010) Cell Mol Immunol , vol.7 , pp. 11-19
    • Xu, Z.1    Jin, B.2
  • 66
    • 79955592674 scopus 로고    scopus 로고
    • CD155 on human vascular endothelial cells attenuates the acquisition of effector functions in CD8 T cells
    • Escalante NK, von Rossum A, Lee M, Choy JC, (2011) CD155 on human vascular endothelial cells attenuates the acquisition of effector functions in CD8 T cells. Arterioscler Thromb Vasc Biol 31: 1177-1184.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1177-1184
    • Escalante, N.K.1    von Rossum, A.2    Lee, M.3    Choy, J.C.4
  • 67
    • 0035811834 scopus 로고    scopus 로고
    • The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin
    • Lange R, Peng X, Wimmer E, Lipp M, Bernhardt G, (2001) The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin. Virology 285: 218-227.
    • (2001) Virology , vol.285 , pp. 218-227
    • Lange, R.1    Peng, X.2    Wimmer, E.3    Lipp, M.4    Bernhardt, G.5
  • 68
    • 0033906634 scopus 로고    scopus 로고
    • Structure and function of the type 1 insulin-like growth factor receptor
    • Adams TE, Epa VC, Garrett TP, Ward CW, (2000) Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci 57: 1050-1093.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1050-1093
    • Adams, T.E.1    Epa, V.C.2    Garrett, T.P.3    Ward, C.W.4
  • 69
    • 0030250337 scopus 로고    scopus 로고
    • Autocrine/paracrine mechanism of insulin-like growth factor-1 secretion, and the effect of insulin-like growth factor-1 on proteoglycan synthesis in bovine intervertebral discs
    • Osada R, Ohshima H, Ishihara H, Yudoh K, Sakai K, et al. (1996) Autocrine/paracrine mechanism of insulin-like growth factor-1 secretion, and the effect of insulin-like growth factor-1 on proteoglycan synthesis in bovine intervertebral discs. J Orthop Res 14: 690-699.
    • (1996) J Orthop Res , vol.14 , pp. 690-699
    • Osada, R.1    Ohshima, H.2    Ishihara, H.3    Yudoh, K.4    Sakai, K.5
  • 70
    • 0035890099 scopus 로고    scopus 로고
    • Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells
    • Okuda S, Myoui A, Ariga K, Nakase T, Yonenobu K, et al. (2001) Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells. Spine (Phila Pa 1976) 26: 2421-2426.
    • (2001) Spine (Phila Pa 1976) , vol.26 , pp. 2421-2426
    • Okuda, S.1    Myoui, A.2    Ariga, K.3    Nakase, T.4    Yonenobu, K.5
  • 71
    • 29744453149 scopus 로고    scopus 로고
    • Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc
    • Le Maitre CL, Richardson SM, Baird P, Freemont AJ, Hoyland JA, (2005) Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc. J Pathol 207: 445-452.
    • (2005) J Pathol , vol.207 , pp. 445-452
    • Le Maitre, C.L.1    Richardson, S.M.2    Baird, P.3    Freemont, A.J.4    Hoyland, J.A.5
  • 72
  • 73
    • 0034282695 scopus 로고    scopus 로고
    • Anti-apoptotic effects of IGF-1 and PDGF on human intervertebral disc cells in vitro
    • Gruber HE, Norton HJ, Hanley EN Jr, (2000) Anti-apoptotic effects of IGF-1 and PDGF on human intervertebral disc cells in vitro. Spine (Phila Pa 1976) 25: 2153-2157.
    • (2000) Spine (Phila Pa 1976) , vol.25 , pp. 2153-2157
    • Gruber, H.E.1    Norton, H.J.2    Hanley Jr., E.N.3
  • 74
    • 0035067622 scopus 로고    scopus 로고
    • Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures
    • Baer AE, Wang JY, Kraus VB, Setton LA, (2001) Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. J Orthop Res 19: 2-10.
    • (2001) J Orthop Res , vol.19 , pp. 2-10
    • Baer, A.E.1    Wang, J.Y.2    Kraus, V.B.3    Setton, L.A.4
  • 75
    • 0036290283 scopus 로고    scopus 로고
    • Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity
    • Chen J, Baer AE, Paik PY, Yan W, Setton LA, (2002) Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. Biochem Biophys Res Commun 293: 932-938.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 932-938
    • Chen, J.1    Baer, A.E.2    Paik, P.Y.3    Yan, W.4    Setton, L.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.