A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients

International Journal of Oncology

Volumn 41, Issue 4, 2012, Pages 1405-1410

  Dasgupta, Santanu ^a   Pal, Prodipto ^b   Mukhopadhyay, Nitai D ^a   Fu, Yumei ^b   Ratovitski, Edward A ^b   Moon, Chul So ^b   Hoque, Mohammad Obaidul ^b   Fisher, Paul B ^a   Trink, Barry ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

3 ; Colorectal cancer; PIGK; Single nucleotide polymorphism; UTR

Indexed keywords

PHOSPHATIDYLINOSITOL; PROTEIN PHOSPHATIDYLINOSITOL GLYCAN, CLASS A; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARAB; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; COLORECTAL CANCER; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC TRANSFECTION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JEW; PHOSPHATIDYLINOSITOL GLYCAN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM;

3' UNTRANSLATED REGIONS; ALLELES; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; COLORECTAL NEOPLASMS; DISEASE SUSCEPTIBILITY; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC ASSOCIATION STUDIES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MUTATION; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84866514143     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1567     Document Type: Article

References (19)

1. Markowitz SD and Bertagnoli MM: Molecular basis of colorectal cancer. N Engl J Med 361: 2449-2460, 2010.
2. Barchana M, Liphshitz I and Rozen P: Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations. Fam Cancer 3: 207-214, 2004.
3. Rozen P, Rosner G, Liphshitz I and Barchana M: The changing incidence and sites of colorectal cancer in the Israeli Arab population and their clinical implications. Int J Cancer 120: 147-151, 2007.
4. Rozen P, Liphshitz I and Barchana M: Changing sites of colorectal cancer in the Israeli Jewish ethnic populations and its clinical implications. Eur J Cancer Prev 16: 1-9, 2007.
5. Poynter JN, Figueiredo JC, Conti DV, et al: Colon CFR: Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res 67: 11128-11132, 2007.
6. Pittman AM, Webb E, Carvajal-Carmona L, et al: Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. Hum Mol Genet 17: 3720-3727, 2008.
7. Tomlinson IP, Webb E, Carvajal-Carmona L, et al: A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 40: 623-630, 2008.
8. Tenesa A, Farrington SM, Prendergast JG, et al: Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 40: 631-637, 2008.
9. Cheah PY: Recent advances in colorectal cancer genetics and diagnostics. Crit Rev Oncol Hematol 69: 45-55, 2009.
10. Zacks MA and Garg N: Recent developments in the molecular, biochemical and functional characterization of GPI8 and the GPI-anchoring mechanism. Mol Membr Biol 23: 209-225, 2006.
11. Nagpal JK, Dasgupta S, Jadallah S, Chae YK, Ratovitski EA, Toubaji A, Netto GJ, Nissan A, Sidransky D and Trink B: Profiling the expression pattern of GPI transamidase complex subunits in human cancer. Mod Pathol 8: 979-991, 2008.
12. Dasgupta S, Mukherjee N, Roy S, Roy A, Sengupta A, Roychowdhury S and Panda CK: Mapping of the candidate tumor suppressor genes' loci on human chromosome 3 in head and neck squamous cell carcinoma of an Indian patient population. Oral Oncol 38: 6-15, 2002.
13. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW Jr and Chatterjee SK: Reversal of immune suppression in an orthotopic murine model of head and neck squamous cell carcinoma following vaccination with recombinant vaccinia virus expressing IL-2. Cancer Ther 2: 375-388, 2004.
14. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW Jr and Chatterjee SK: Inhibition of NK cell activity through TGF-1 by down regulation of NKG2D in a murine model of head and neck cancer. J Immunol 175: 5541-5550, 2005.
15. Ali MA and Sjoblom T: Molecular pathways in tumor progression: from discovery to functional understanding. Mol Biosyst 5: 902-908, 2009.
16. http://www.ncbi.nlm.nih.gov.
17. Pongsavee M, Yamkamon V, Dakeng S, O-charoenrat P, Smith DR, Saunders GF and Patmasiriwat P: The BRCA1 3′-UTR: 5711+421T/T-5711+1286T/T genotype is a possible breast and ovarian cancer risk factor. Genet Test Mol Biomarkers 13: 307-317, 2009.
18. Olena AF and Patton JG: Genomic organization of microRNAs. J Cell Physiol 222: 540-545, 2010.
19. Iorio MV and Croce CM: MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 27: 5848-5856, 2009.