The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element

Development

Volumn 125, Issue 19, 1998, Pages 3887-3894

  Casey, Elena Silva ^a   O'Reilly, Marie Anne J ^a,b   Conlon, Frank L ^a   Smith, J C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

FGF; Mesoderm; Notochord; T box protein; Transcriptional regulation; Xenopus

Indexed keywords

DNA; FIBROBLAST GROWTH FACTOR; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; EMBRYO; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; TRANSCRIPTION REGULATION; XENOPUS;

ANIMALS; BASE SEQUENCE; BINDING SITES; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; FETAL PROTEINS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MESODERM; MICE; NOTOCHORD; PROMOTER REGIONS (GENETICS); T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS; XENOPUS;

ANIMALIA; VERTEBRATA; XENOPUS BRACHYURY;

EID: 0031792721     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Amaya, E. and Kroll, K. L. (1998). A method for generating transgenic frog embryos. In Methods in Cell Biology. Molecular Embryology: Methods and Protocols (ed. P. Sharpe and I. Mason), pp. Totowa, NJ: Humana Press Inc. (In press).
2. Amaya, E., Musci, T. J. and Kirschner, M. W. (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.
3. Ambrosetti, D. C., Basilico, C. and Dailey, L. (1997). Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol. Cell Biol. 17, 6321-6329.
4. Conlon, F. L., Sedgwick, S. G., Weston, K. M. and Smith, J. C. (1996). Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122, 2427-2435.
5. Cunliffe, V. and Smith, J. C. (1992). Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature 358, 427-430.
6. Dyson, S. and Gurdon, J. B. (1996). Activin signalling has a necessary function in Xenopus early development. Current Biology 7, 81-84.
7. Gotoh, Y., Masuyama, N., Suzuki, A., Ueno, N. and Nishida, E. (1995). Involvement of the MAP kinase cascade in Xenopus mesoderm induction. EMBO J. 14, 2491-2498.
8. Halpern, M. E., Ho, R. K., Walker, C. and Kimmel, C. B. (1993). Induction of muscle pioneers and Moor plate is distinguished by the zebrafish no tail mutation. Cell 75, 99-111.
9. Henikoff, S. (1990). Ordered deletions for DNA sequencing and in vitro mutagenesis by polymerase extension and exonuclease III gapping of circular templates. Nuc. Acids Res, 18, 2961-2966.
10. Herrmann, B. G. and Kispert, A. (1994). The T genes in embryogenesis. Trends Genet. 10, 280-286.
11. Herrmann, B. G., Labeit, S., Poutska, A., King, T. R. and Lehrach, H. (1990). Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622.
12. Isaacs, H. V., Pownall, M. E. and Slack, J. M. W. (1994). eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13, 4469-4481.
13. Isaacs, H. V., Pownall, M. E. and Slack, J. M. W. (1995). eFGF is expressed in the dorsal mid-line of Xenopus laevis. Int. J. Dev Biol. 39, 575-579.
14. Isaacs, H. V., Tannahill, D. and Slack, J. M. W. (1992). Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification. Development 114, 711-720.
15. Kay, B. K. (1991). Injection of oocytes and embryos. In Xenopus laevis: Practical Uses in Cell and Molecular Biology, vol. 36 (ed. B. K. Kay and H. B. Peng), pp. 663-669. San Diego: Academic Press.
16. Kispert, A. and Herrmann, B. G. (1993). The Brachyury gene encodes a novel DNA binding protein. EMBO J. 12, 3211-3220.
17. Kispert, A., Korschorz, B. and Herrmann, B. G. (1995). The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO J. 14, 4763-4772.
18. Kroll, K. L. and Amaya, E. (1996). Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signalling requirements during gastrulation. Development 122, 3173-3183.
19. LaBonne, C., Burke, B. and Whitman, M. (1995). Role of MAP kinase in mesoderm Induction and axial patterning during Xenopus development. Development 121, 1475-1486.
20. Latinkic, B. V., Umbhauer, M., Neal, K. A., Lerchner, W., Smith, J. C. and Cunliffe, V. (1997). The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev. 11, 3265-3267.
21. Modak, S. P., Principaud, E. and Spohr, G. (1993). Regulation of Xenopus c-myc promoter activity in oocytes and embryos. Oncogen 8, 645-654.
22. Mohun, T., Garrett, N. and Treisman, R. (1987). Xenopus cytoskeletal actin and human c-fos promoters share a conserved protein-binding site. EMBO J. 6, 667-673.
23. Muller, C. W. and Herrmann, B. G. (1997). Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature 389, 884-888.
24. Nieuwkoop, P. D. and Faber, J. (1975). Normal Table of Xenopus laevis (Daudin). Amsterdam: North Holland.
25. Papapetrou, C., Edwards, Y. H. and Sowden, J. C. (1997). The T transcription factor functions as a dimer and exhibits a common human polymorphism Gly-177-Asp in the conserved DNA-binding domain. FEBS Lett. 409, 201-206.
26. Schmidt, C., Wilson, V., Stott, D. and Beddington, R. S. P. (1997). T promoter activity in the absence of functional T protein during axis formation and elongation in the mouse. Dev. Biol. 189, 161-173.
27. Schulte-Merker, S. and Smith, J. C. (1995). Mesoderm formation in response to Brachyury requires FGF signalling. Curr. Biol. 5, 62-67.
28. Schulte-Merker, S., van Eeden, F. M., Halpern, M. E., Kimmel, C. B. and Nüsslein-Volhard, C. (1994). No tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development 120, 1009-1015.
29. Sive, H. L. (1993). The frog prince-ss: A molecular formula for dorsoventral patterning in Xenopus. Genes Dev. 7, 1-12.
30. Slack, J. M. W. (1984). Regional biosynthetic markers in the early amphibian embryo. J. Embryol Exp. Morph 80, 289-319.
31. Slack, J. M. W.(1994). Inducing factors in Xenopus early embryos. Curr. Biol. 4, 116-126.
32. Smith, J. (1997). Brachyury and the T-box genes. Curr Opin. Gen. Dev. 7, 474-480.
33. Smith, J. C. (1993). Purifying and assaying mesoderm-inducing factors from vertebrate embryos. In Cellular Interactions in Development - a Practical Approach (ed. D. Hartley), pp. 181-204. Oxford: Oxford University Press.
34. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Herrmann, B. G. (1991). Expression of a Xenopus homolog of Bmchyury (7) is an immediate-earl y response to mesoderm induction. Cell 67, 79-87.
35. Symes, K., Yaqoob, M. and Smith, J. C. (1988). Mesoderm induction in Xenopus laevis: responding cells must be in contact for mesoderm formation but suppression of epidermal differentiation can occur in single cells. Development 104, 609-618.
36. Tada, M., O'Reilly, M.-A. J. and Smith, J. C. (1997). Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra. Development 124, 2225-2234.
37. Umbhauer, M., Marshall, C. J., Mason, C. S., Old, R. W. and Smith, J. C. (1995). Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62.
38. Yuan, H., Corbi, N., Basilico, C. and Dailey, L. (1995). Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev. 9, 2635-2645.