Making mesoderm - Upstream and downstream of Xbra

International Journal of Developmental Biology

Volumn 45, Issue 1, 2001, Pages 219-224

  Smith, J C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Brachyury; Induction; Mesoderm; Transcription; Xenopus

Indexed keywords

FIBROBLAST GROWTH FACTOR;

ARTICLE; EMBRYO; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE FUNCTION; MESODERM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; XENOPUS;

ANIMALS; BASE SEQUENCE; BINDING SITES; BODY PATTERNING; DNA; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MESODERM; PROTO-ONCOGENE PROTEINS; T-BOX DOMAIN PROTEINS; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS; ZEBRAFISH PROTEINS;

AMPHIBIA; VERTEBRATA; XENOPUS BRACHYURY;

EID: 0035072541     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. The genetic control of tissue polarity in Drosophila
2. A method for generating transgenic frog embryos
3. A short loop on the ALK-2 and ALK-4 activin receptors regulates signaling specificity but cannot account for all their effects on early Xenopus development
4. The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm- inducing signals during early Xenopus development but do not co-operate to establish thresholds
5. Interaction of goosecoid and brachyury in Xenopus mesoderm patterning
6. Dishevelled: At the crossroads of divergent intracellular signaling pathways
7. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
8. Wnt signaling: A common theme in animal development
9. The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element
10. Bix4 is activated directly by VegT and mediates endoderm formation in Xenopus development
11. Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm
12. Interference with Bachyury function inhibits convergent extension, causes apoptosis, and reveals separate requirements in the FGF and activin signalling pathways
13. Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue
14. Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8
15. Sur la mortification spontanée de la queue chez la souris nouveau-née et sur l'existence d'un caractère heriditaire "nonviable"
16. A novel Xenopus mix-like gene milk involved in the control of the endomesodermal fates
17. XSIP1, a member of two-handed zinc finger proteins, induced anterior neural markers in Xenopus laevis animal cap
18. Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif
19. The development of two tailless mutants in the house mouse
20. Involvement of the MAP kinase cascade in Xenopus mesoderm induction
21. Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
22. Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern
23. Activin signalling and response to a morphogen gradient
24. Direct and continuous assessment by cells of their position in a morphogen gradient
25. Formation and function of Spemann's organizer
26. Genes involved in forebrain development in the zebrafish, Danio rerio
27. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
28. Mixer, a homeobox gene required for endoderm development
29. Cloning of the T gene required in mesoderm formation in the mouse
30. Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos
31. A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation
32. eFGF regulates Xbra expression during Xenopus gastrulation
33. eFGF is expressed in the dorsal midline of Xenopus laevis
34. Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification
35. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
36. Xnr4: A Xenopus nodal-related gene expressed in the Spemann organizer
37. The Brachyury gene encodes a novel DNA binding protein
38. The T protein encoded by Brachyury is a tissue-specific transcription factor
39. Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors
40. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation
41. Xwnt-11, a maternally expressed Xenopus wnt gene
42. Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development
43. Goosecoid and Mix.1 repress Brachyury expression and are required for head formation in Xenopus
44. The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins
45. Region-specific activation of the Xenopus Brachyury promoter involves active repression in ectoderm and endoderm: A study using transgenic frog embryos
46. Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation
47. Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins
48. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
49. Patterning of the mesoderm in Xenopus: Dose-dependent and synergistic effects of Brachyury and Pintallavis
50. The T-box gene family
51. Gradual refinement of activin-induced thresholds requires protein synthesis
52. New mode of DNA binding of multi-zinc finger transcription factors: DeltaEF1 family members bind with two hands to two target sites
53. Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos
54. A screen for targets of the Xenopus T-box gene Xbra
55. Mesoderm formation in response to Brachyury requires FGF signalling
56. Two mechanisms in the action of repressor deltaEF1: Binding site competition with an activator and active repression
57. T-box genes: What they do and how they do it
58. Brachyury and the T-box genes
59. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
60. A nodal-related gene defines a physical and functional domain within the Spemann organizer
61. The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation
62. The role of RhoA in tissue polarity and Frizzled signalling
63. Derrière: A TGF-beta family member required for posterior development in Xenopus
64. Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm
65. Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra
66. Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via dishevelled, but not through the canonical Wnt pathway
67. Mesoderm induction in Xenopus caused by activation of MAP kinase
68. XSIP1, a Xenopus zinc finger/homeodomain encoding gene highly expressed during early neural development
69. SIP1, a novel zinc finger/homeodomain repressor, interacts with smad proteins and binds to 5′-CACCT sequences in candidate target genes
70. DNA sequences mediating the transcriptional response of the Mix.2 homeobox gene to mesoderm induction
71. Dishevelled controls cell polarity during Xenopus gastrulation
72. Expression pattern of the mouse T gene and its role in mesoderm formation
73. The role of maternal VegT in establishing the primary germ layers in Xenopus embryos
74. Xenopus VegT RNA is localized to the vegetal codex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning